The influence of genetic background on the induction of oxidative stress and impaired insulin secretion in mouse islets. (Q54611520)

1 June 2018

title

The influence of genetic background on the induction of oxidative stress and impaired insulin secretion in mouse islets. (English)

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1 June 2018

author

Melkam Kebede

4

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1 June 2018

Kathryn Aston-Mourney

object named as

K Aston-Mourney

2

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author name string

S Zraika

1

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D R Laybutt

3

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M E Dunlop

5

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J Proietto

6

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S Andrikopoulos

7

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publication date

29 March 2006

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1 June 2018

published in

Diabetologia

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volume

49

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issue

6

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page(s)

1254-1263

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Mechanisms of pancreatic B-cell dysfunction and glucose toxicity in non-insulin-dependent diabetes

cites work

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Crossref

https://api.crossref.org/works/10.1007%2FS00125-006-0212-9

Hydroxyl radical production and autoxidative glycosylation. Glucose autoxidation as the cause of protein damage in the experimental glycation model of diabetes mellitus and ageing

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Isolation of highly purified mitochondria from rat pancreas

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Sequential inactivation of reactive oxygen species by combined overexpression of SOD isoforms and catalase in insulin-producing cells

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Oxidative stress is a mediator of glucose toxicity in insulin-secreting pancreatic islet cell lines

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Mechanisms by which glucose can control insulin release independently from its action on adenosine triphosphate-sensitive K+ channels in mouse B cells

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Temporal changes in pancreatic islet composition in c57bl/6j-db/db (diabetes) mice

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Chronic hyperglycemia impairs insulin secretion by affecting insulin receptor expression, splicing, and signaling in RIN β‐cell line and human islets of Langerhans

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Beta-cell dysfunction induced by chronic hyperglycemia. Current ideas on mechanism of impaired glucose-induced insulin secretion

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Role of the glucosamine pathway in fat-induced insulin resistance

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Glucose toxicity in beta-cells: type 2 diabetes, good radicals gone bad, and the glutathione connection

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Activation of the hexosamine pathway leads to deterioration of pancreatic beta-cell function through the induction of oxidative stress

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Transgenic mice with increased hexosamine flux specifically targeted to beta-cells exhibit hyperinsulinemia and peripheral insulin resistance.

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Normalizing mitochondrial superoxide production blocks three pathways of hyperglycaemic damage

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Prolonged exposure of human pancreatic islets to high glucose concentrations in vitro impairs the beta-cell function

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Induction of glycation suppresses glucokinase gene expression in HIT-T15 cells

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The dynamic insulin secretory response of isolated pancreatic islets of the diabetic mouse. Evidence for a gene dosage effect on insulin secretion

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Glucosamine inhibits glucokinase in vitro and produces a glucose-specific impairment of in vivo insulin secretion in rats

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Importance of mitochondrial superoxide dismutase expression in insulin-producing cells for the toxicity of reactive oxygen species and proinflammatory cytokines.

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A role for glutathione peroxidase in protecting pancreatic beta cells against oxidative stress in a model of glucose toxicity

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High glucose-induced impairment in insulin secretion is associated with reduction in islet glucokinase in a mouse model of susceptibility to islet dysfunction

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12 December 2020

D-Glyceraldehyde causes production of intracellular peroxide in pancreatic islets, oxidative stress, and defective beta cell function via non-mitochondrial pathways

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Glycan-dependent signaling: O-linked N-acetylglucosamine

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Aberrant function and long-term survival of mouse beta cells exposed in vitro to high glucose concentrations

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Coupling of beta-cell desensitization by hyperglycemia to excessive stimulation and circulating insulin in glucose-infused rats

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Why does SOD overexpression sometimes enhance, sometimes decrease, hydrogen peroxide production? A minimalist explanation.

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Monolayer Culture of Adult Rat Pancreatic Islets on Extracellular Matrix: Modulation of B-Cell Function by Chronic Exposure to High Glucose*

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Role of oxidative stress in development of complications in diabetes

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In vivo glucosamine infusion induces insulin resistance in normoglycemic but not in hyperglycemic conscious rats

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Functional and molecular defects of pancreatic islets in human type 2 diabetes

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Elevated SNAP-25 is associated with fatty acid-induced impairment of mouse islet function

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Discovery of a metabolic pathway mediating glucose-induced desensitization of the glucose transport system. Role of hexosamine biosynthesis in the induction of insulin resistance

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Preservation of insulin mRNA levels and insulin secretion in HIT cells by avoidance of chronic exposure to high glucose concentrations

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Hyperglycemia causes oxidative stress in pancreatic beta-cells of GK rats, a model of type 2 diabetes.

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The influence of genetic background on the expression of mutations at the diabetes locus in the mouse. III. Effect of H-2 haplotype and sex.

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Beneficial effects of antioxidants in diabetes: possible protection of pancreatic beta-cells against glucose toxicity

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Chronic exposure of betaTC-6 cells to supraphysiologic concentrations of glucose decreases binding of the RIPE3b1 insulin gene transcription activator

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Beta-cell glucose toxicity, lipotoxicity, and chronic oxidative stress in type 2 diabetes

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Single-Step Method of RNA Isolation by Acid Guanidinium Thiocyanate–Phenol–Chloroform Extraction

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Protection against the co-operative toxicity of nitric oxide and oxygen free radicals by overexpression of antioxidant enzymes in bioengineered insulin-producing RINm5F cells

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Prevention of glucose toxicity in HIT-T15 cells and Zucker diabetic fatty rats by antioxidants

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12 December 2020

The hexosamine biosynthesis pathway regulates insulin secretion via protein glycosylation in mouse islets

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12 December 2020

Comparison of insulin secretory function in two mouse models with different susceptibility to beta-cell failure

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12 December 2020

Mitochondrial catalase overexpression protects insulin-producing cells against toxicity of reactive oxygen species and proinflammatory cytokines.

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12 December 2020

Dynamic O-linked glycosylation of nuclear and cytoskeletal proteins

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12 December 2020

Purification of the O-glycosylated protein p135 and identification as O-GlcNAc transferase

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12 December 2020

Does the glucose-dependent insulin secretion mechanism itself cause oxidative stress in pancreatic beta-cells?

1 reference

12 December 2020

Low antioxidant enzyme gene expression in pancreatic islets compared with various other mouse tissues.

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12 December 2020

10.1007/S00125-006-0212-9

Identifiers

DOI

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1 June 2018

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1 June 2018