Is there a biological cost of protein disorder? Analysis of cancer-associated mutations (Q57080287)

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12 February 2020

title

Is there a biological cost of protein disorder? Analysis of cancer-associated mutations (English)

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12 February 2020

2

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12 February 2020

Istvan Simon

series ordinal

3

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12 February 2020

Zsuzsanna Dosztányi

series ordinal

4

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author name string

Mátyás Pajkos

series ordinal

1

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12 February 2020

publication date

14 September 2011

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12 February 2020

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12 February 2020

volume

8

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issue

1

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page(s)

296-307

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Intrinsically disordered protein

12 February 2020

cites work

1 reference

https://api.crossref.org/works/10.1039%2FC1MB05246B

Intrinsically unstructured proteins and their functions

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC1MB05246B

Intrinsically unstructured proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC1MB05246B

Prediction and Functional Analysis of Native Disorder in Proteins from the Three Kingdoms of Life

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC1MB05246B

The interplay between structure and function in intrinsically unstructured proteins.

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC1MB05246B

Extended disordered proteins: targeting function with less scaffold

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC1MB05246B

Coupling of folding and binding for unstructured proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC1MB05246B

Flexible nets: disorder and induced fit in the associations of p53 and 14-3-3 with their partners

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC1MB05246B

The importance of intrinsic disorder for protein phosphorylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC1MB05246B

Regulation of cell division by intrinsically unstructured proteins: intrinsic flexibility, modularity, and signaling conduits

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC1MB05246B

Functional anthology of intrinsic disorder. 1. Biological processes and functions of proteins with long disordered regions.

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC1MB05246B

Intrinsic disorder is a common feature of hub proteins from four eukaryotic interactomes

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC1MB05246B

Disorder and sequence repeats in hub proteins and their implications for network evolution.

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC1MB05246B

Intrinsically Disordered Proteins in Human Diseases: Introducing the D 2 Concept

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC1MB05246B

21 January 2018

Surfing the p53 network

1 reference

https://api.crossref.org/works/10.1039%2FC1MB05246B

Intrinsic disorder in cell-signaling and cancer-associated proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC1MB05246B

Intrinsic structural disorder confers cellular viability on oncogenic fusion proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC1MB05246B

Intrinsic disorder in proteins associated with neurodegenerative diseases

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC1MB05246B

Structural disorder in amyloid fibrils: its implication in dynamic interactions of proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC1MB05246B

dbSNP: the NCBI database of genetic variation

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC1MB05246B

Variation in genome-wide mutation rates within and between human families

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC1MB05246B

A map of human genome variation from population-scale sequencing

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC1MB05246B

Natural selection of protein structural and functional properties: a single nucleotide polymorphism perspective

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC1MB05246B

Mutational analysis of gene families in human cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC1MB05246B

Big science: The cancer genome challenge

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC1MB05246B

The consensus coding sequences of human breast and colorectal cancers

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC1MB05246B

The genomic landscapes of human breast and colorectal cancers

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC1MB05246B

Core signaling pathways in human pancreatic cancers revealed by global genomic analyses

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC1MB05246B

An integrated genomic analysis of human glioblastoma multiforme

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC1MB05246B

Annotating single amino acid polymorphisms in the UniProt/Swiss-Prot knowledgebase.

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC1MB05246B

COSMIC: mining complete cancer genomes in the Catalogue of Somatic Mutations in Cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC1MB05246B

A census of human cancer genes

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC1MB05246B

Ongoing and future developments at the Universal Protein Resource

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC1MB05246B

IUPred: web server for the prediction of intrinsically unstructured regions of proteins based on estimated energy content

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC1MB05246B

The pairwise energy content estimated from amino acid composition discriminates between folded and intrinsically unstructured proteins.

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC1MB05246B

Length-dependent prediction of protein intrinsic disorder.

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC1MB05246B

Structural and functional properties of genes involved in human cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC1MB05246B

Integrated assessment of genomic correlates of protein evolutionary rate

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC1MB05246B

Evolutionary rate heterogeneity in proteins with long disordered regions.

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC1MB05246B

21 January 2018

Evolution and disorder

1 reference

https://api.crossref.org/works/10.1039%2FC1MB05246B

Molecular Principles of the Interactions of Disordered Proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC1MB05246B

The expanding view of protein-protein interactions: complexes involving intrinsically disordered proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC1MB05246B

Prediction of protein binding regions in disordered proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC1MB05246B

ANCHOR: web server for predicting protein binding regions in disordered proteins.

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC1MB05246B

Mining alpha-helix-forming molecular recognition features with cross species sequence alignments

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC1MB05246B

The Pfam protein families database

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC1MB05246B

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC1MB05246B

Shaping genetic alterations in human cancer: the p53 mutation paradigm

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC1MB05246B

Structural biology of the tumor suppressor p53 and cancer-associated mutants

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC1MB05246B

p53 contains large unstructured regions in its native state

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC1MB05246B

PTEN loss in the continuum of common cancers, rare syndromes and mouse models.

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC1MB05246B

PTEN: a tumour suppressor that functions as a phospholipid phosphatase

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC1MB05246B

Par-3-mediated junctional localization of the lipid phosphatase PTEN is required for cell polarity establishment

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC1MB05246B

PTEN tumor suppressor regulates p53 protein levels and activity through phosphatase-dependent and -independent mechanisms

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC1MB05246B

The multi-talented beta-catenin makes its first appearance

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC1MB05246B

Signal transduction of beta-catenin

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC1MB05246B

Structure of a beta-TrCP1-Skp1-beta-catenin complex: destruction motif binding and lysine specificity of the SCF(beta-TrCP1) ubiquitin ligase

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC1MB05246B

Phosphorylation and ubiquitination of oncogenic mutants of beta-catenin containing substitutions at Asp32.

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC1MB05246B

Association of the APC gene product with beta-catenin

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC1MB05246B

Association of the APC tumor suppressor protein with catenins

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC1MB05246B

Crystal structure of a beta-catenin/APC complex reveals a critical role for APC phosphorylation in APC function

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC1MB05246B

Molecular mechanisms of beta-catenin recognition by adenomatous polyposis coli revealed by the structure of an APC-beta-catenin complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC1MB05246B

Conservation and relative importance of residues across protein-protein interfaces

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC1MB05246B

ConSurf 2005: the projection of evolutionary conservation scores of residues on protein structures

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC1MB05246B

Local structural disorder imparts plasticity on linear motifs.

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC1MB05246B

Tight regulation of unstructured proteins: from transcript synthesis to protein degradation

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC1MB05246B

Intrinsically disordered proteins: regulation and disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC1MB05246B

The UCSC Cancer Genomics Browser: update 2011

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC1MB05246B

Gene ontology: tool for the unification of biology

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC1MB05246B

The IntAct molecular interaction database in 2010

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC1MB05246B

Frequent somatic mutations in PTEN and TP53 are mutually exclusive in the stroma of breast carcinomas

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC1MB05246B

21 January 2018

Identifiers

DOI

10.1039/C1MB05246B

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21918772%20AND%20SRC:MED&resulttype=core&format=json

12 February 2020

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