Pancreatic β-cells activate a JunB/ATF3-dependent survival pathway during inflammation (Q57503330)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21841823%20AND%20SRC:MED&resulttype=core&format=json

10 February 2020

title

Pancreatic β-cells activate a JunB/ATF3-dependent survival pathway during inflammation (English)

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10 February 2020

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10 February 2020

Fernanda Ortis

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10 February 2020

Piero Marchetti

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10 February 2020

Erwin F. Wagner

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10 February 2020

Mariana Igoillo-Esteve

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M Igoillo-Esteve

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Chantal Mathieu

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C Mathieu

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author name string

J Barthson

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10 February 2020

I Marhfour

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10 February 2020

N Naamane

5

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10 February 2020

C Gysemans

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10 February 2020

S Kitajima

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10 February 2020

T F Ørntoft

11

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10 February 2020

L Bakiri

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10 February 2020

D L Eizirik

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language of work or name

English

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publication date

15 August 2011

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10 February 2020

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10 February 2020

volume

31

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10 February 2020

issue

13

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10 February 2020

page(s)

1723-1732

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Mcl-1 downregulation by pro-inflammatory cytokines and palmitate is an early event contributing to β-cell apoptosis

10 February 2020

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Time for testing incretin therapies in early type 1 diabetes?

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Cytokines downregulate the sarcoendoplasmic reticulum pump Ca2+ ATPase 2b and deplete endoplasmic reticulum Ca2+, leading to induction of endoplasmic reticulum stress in pancreatic beta-cells

21 January 2018

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Islet beta-cells deficient in Bcl-xL develop but are abnormally sensitive to apoptotic stimuli

21 January 2018

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MDA5 and PTPN2, two candidate genes for type 1 diabetes, modify pancreatic beta-cell responses to the viral by-product double-stranded RNA.

21 January 2018

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Initiation and execution of lipotoxic ER stress in pancreatic beta-cells

21 January 2018

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Glucagon-like peptide-1 agonists protect pancreatic beta-cells from lipotoxic endoplasmic reticulum stress through upregulation of BiP and JunB.

21 January 2018

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AP-1: a double-edged sword in tumorigenesis

21 January 2018

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The role of inflammation in insulitis and beta-cell loss in type 1 diabetes

21 January 2018

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A choice of death--the signal-transduction of immune-mediated beta-cell apoptosis

21 January 2018

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Guidelines for the use and interpretation of assays for monitoring cell death in higher eukaryotes.

21 January 2018

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p53 up-regulated modulator of apoptosis (PUMA) activation contributes to pancreatic beta-cell apoptosis induced by proinflammatory cytokines and endoplasmic reticulum stress

21 January 2018

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JunB Inhibits ER Stress and Apoptosis in Pancreatic Beta Cells

21 January 2018

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Activating transcription factor 3 is integral to the eukaryotic initiation factor 2 kinase stress response

21 January 2018

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Expression of stress-response ATF3 is mediated by Nrf2 in astrocytes

21 January 2018

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cAMP-dependent regulation of proenkephalin by JunD and JunB: positive and negative effects of AP-1 proteins

21 January 2018

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Histone modifications defining active genes persist after transcriptional and mitotic inactivation

21 January 2018

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Discovery of Gene Networks Regulating Cytokine-Induced Dysfunction and Apoptosis in Insulin-Producing INS-1 Cells

21 January 2018

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Prolonged exposure to free fatty acids has cytostatic and pro-apoptotic effects on human pancreatic islets: evidence that beta-cell death is caspase mediated, partially dependent on ceramide pathway, and Bcl-2 regulated.

21 January 2018

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The glucagon-like peptide-1 receptor agonist oxyntomodulin enhances beta-cell function but does not inhibit gastric emptying in mice

21 January 2018

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Regulation of MafA expression in pancreatic beta-cells in db/db mice with diabetes

21 January 2018

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Epidermal JunB represses G-CSF transcription and affects haematopoiesis and bone formation

21 January 2018

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PTPN2, a candidate gene for type 1 diabetes, modulates interferon-gamma-induced pancreatic beta-cell apoptosis

21 January 2018

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STAT1 is a master regulator of pancreatic {beta}-cell apoptosis and islet inflammation

21 January 2018

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Transcriptional regulatory elements downstream of the JunB gene

21 January 2018

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Epidermal loss of JunB leads to a SLE phenotype due to hyper IL-6 signaling.

21 January 2018

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Growth factor stimulation induces cell survival by c-Jun. ATF2-dependent activation of Bcl-XL.

21 January 2018

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Critical role for NF-kappaB-induced JunB in VEGF regulation and tumor angiogenesis

21 January 2018

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The human ubiquitin C promoter directs high ubiquitous expression of transgenes in mice

21 January 2018

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AP-1 as a regulator of cell life and death

21 January 2018

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Stress response gene ATF3 is a target of c-myc in serum-induced cell proliferation

21 January 2018

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ATF3 transcription factor and its emerging roles in immunity and cancer

21 January 2018

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Opposing roles for calcineurin and ATF3 in squamous skin cancer

21 January 2018

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Psoriasis-like skin disease and arthritis caused by inducible epidermal deletion of Jun proteins

21 January 2018

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The roles of ATF3, an adaptive-response gene, in high-fat-diet-induced diabetes and pancreatic beta-cell dysfunction.

21 January 2018

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Deficiency of Atf3, an adaptive-response gene, protects islets and ameliorates inflammation in a syngeneic mouse transplantation model.

21 January 2018

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Signaling by IL-1beta+IFN-gamma and ER stress converge on DP5/Hrk activation: a novel mechanism for pancreatic beta-cell apoptosis

21 January 2018

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Inhibition of cytokine-induced NF-kappaB activation by adenovirus-mediated expression of a NF-kappaB super-repressor prevents beta-cell apoptosis

31 March 2020

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A new in vitro model for the study of pancreatic A and B cells

31 March 2020

1 reference

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31 March 2020

Identifiers

DOI

10.1038/ONC.2011.353

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21841823%20AND%20SRC:MED&resulttype=core&format=json

10 February 2020

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