A TRAF3-NIK module differentially regulates DNA vs RNA pathways in innate immune signaling (Q59356620)

2

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Anurupa Dev

3

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Saba Roghiyh Aliyari

4

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Shivam A Zaver

5

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Hoda Gerami

6

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Maxime Chapon

7

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Amir A Ghaffari

8

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Anant Dhingra

9

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Genhong Cheng

Creative Commons Attribution 4.0 International

10

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language of work or name

English

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publication date

17 July 2018

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published in

Nature Communications

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volume

9

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issue

1

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page(s)

2770

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copyright license

start time

17 July 2018

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April 2022 Public Data File from Crossref

copyright status

copyrighted

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describes a project that uses

ImageJ

1 reference

Europe PubMed Central

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC6050272/fullTextXML

inferred from PubMed Central ID database lookup

exact match

https://scigraph.springernature.com/pub.10.1038/s41467-018-05168-7

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c-di-AMP secreted by intracellular Listeria monocytogenes activates a host type I interferon response

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ERIS, an endoplasmic reticulum IFN stimulator, activates innate immune signaling through dimerization

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The ubiquitin ligase TRIM56 regulates innate immune responses to intracellular double-stranded DNA

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PPM1A regulates antiviral signaling by antagonizing TBK1-mediated STING phosphorylation and aggregation

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STING specifies IRF3 phosphorylation by TBK1 in the cytosolic DNA signaling pathway

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Targeting signaling factors for degradation, an emerging mechanism for TRAF functions

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STING Activation by Translocation from the ER Is Associated with Infection and Autoinflammatory Disease

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The ubiquitin ligase RNF5 regulates antiviral responses by mediating degradation of the adaptor protein MITA

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Negative feedback regulation of NF-κB-inducing kinase is proteasome-dependent but does not require cellular inhibitors of apoptosis

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Rescue of TRAF3-null mice by p100 NF-kappa B deficiency

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Targeted disruption of TRAF3 leads to postnatal lethality and defective T-dependent immune responses.

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TAX1BP1 and A20 inhibit antiviral signaling by targeting TBK1-IKKi kinases

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