Epigenetic Regulation of Bone Marrow Stem Cell Aging: Revealing Epigenetic Signatures associated with Hematopoietic and Mesenchymal Stem Cell Aging (Q61801371)

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English	Epigenetic Regulation of Bone Marrow Stem Cell Aging: Revealing Epigenetic Signatures associated with Hematopoietic and Mesenchymal Stem Cell Aging	No description defined

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scholarly article

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Epigenetic Regulation of Bone Marrow Stem Cell Aging: Revealing Epigenetic Signatures associated with Hematopoietic and Mesenchymal Stem Cell Aging (English)

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mesenchymal stem cell

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based on heuristic

inferred from title

author name string

Dimitrios Cakouros

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Stan Gronthos

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language of work or name

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publication date

February 2019

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Aging and Disease

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10

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1

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174-189

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Stromal stem cells: marrow-derived osteogenic precursors

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https://pubmed.ncbi.nlm.nih.gov/30705777

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The development of fibroblast colonies in monolayer cultures of guinea-pig bone marrow and spleen cells

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https://pubmed.ncbi.nlm.nih.gov/30705777

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Characterization of human bone marrow fibroblast colony-forming cells (CFU-F) and their progeny

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https://pubmed.ncbi.nlm.nih.gov/30705777

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Loss of transcriptional silencing causes sterility in old mother cells of S. cerevisiae

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https://pubmed.ncbi.nlm.nih.gov/30705777

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effect of replicative age on transcriptional silencing near telomeres in Saccharomyces cerevisiae

1 reference

https://pubmed.ncbi.nlm.nih.gov/30705777

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The heterochromatin loss model of aging

1 reference

https://pubmed.ncbi.nlm.nih.gov/30705777

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The oncogene and Polycomb-group gene bmi-1 regulates cell proliferation and senescence through the ink4a locus

1 reference

https://pubmed.ncbi.nlm.nih.gov/30705777

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Multilineage potential of adult human mesenchymal stem cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/30705777

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Characterization of five human cDNAs with homology to the yeast SIR2 gene: Sir2-like proteins (sirtuins) metabolize NAD and may have protein ADP-ribosyltransferase activity

1 reference

https://pubmed.ncbi.nlm.nih.gov/30705777

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Age-related osteogenic potential of mesenchymal stromal stem cells from human vertebral bone marrow

1 reference

https://pubmed.ncbi.nlm.nih.gov/30705777

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The SIR2/3/4 complex and SIR2 alone promote longevity in Saccharomyces cerevisiae by two different mechanisms

1 reference

https://pubmed.ncbi.nlm.nih.gov/30705777

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The silencing protein SIR2 and its homologs are NAD-dependent protein deacetylases

1 reference

https://pubmed.ncbi.nlm.nih.gov/30705777

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Age-associated characteristics of murine hematopoietic stem cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/30705777

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Increased dosage of a sir-2 gene extends lifespan in Caenorhabditis elegans

1 reference

https://pubmed.ncbi.nlm.nih.gov/30705777

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Bone formation by human postnatal bone marrow stromal stem cells is enhanced by telomerase expression.

1 reference

https://pubmed.ncbi.nlm.nih.gov/30705777

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Telomerase expression extends the proliferative life-span and maintains the osteogenic potential of human bone marrow stromal cells.

1 reference

https://pubmed.ncbi.nlm.nih.gov/30705777

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Stem cell properties of human dental pulp stem cells.

1 reference

https://pubmed.ncbi.nlm.nih.gov/30705777

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The mammalian SIR2alpha protein has a role in embryogenesis and gametogenesis

1 reference

https://pubmed.ncbi.nlm.nih.gov/30705777

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Molecular and cellular characterisation of highly purified stromal stem cells derived from human bone marrow.

1 reference

https://pubmed.ncbi.nlm.nih.gov/30705777

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Bmi-1 is required for maintenance of adult self-renewing haematopoietic stem cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/30705777

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Rb-mediated heterochromatin formation and silencing of E2F target genes during cellular senescence

1 reference

https://pubmed.ncbi.nlm.nih.gov/30705777

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Developmental defects and p53 hyperacetylation in Sir2 homolog (SIRT1)-deficient mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/30705777

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Age related changes in 5-methylcytosine content in human peripheral leukocytes and placentas: an HPLC-based study

1 reference

https://pubmed.ncbi.nlm.nih.gov/30705777

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Study of telomere length reveals rapid aging of human marrow stromal cells following in vitro expansion

1 reference

https://pubmed.ncbi.nlm.nih.gov/30705777

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Sir2 mediates longevity in the fly through a pathway related to calorie restriction

1 reference

https://pubmed.ncbi.nlm.nih.gov/30705777

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Enhanced self-renewal of hematopoietic stem cells mediated by the polycomb gene product Bmi-1

1 reference

https://pubmed.ncbi.nlm.nih.gov/30705777

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Formation of MacroH2A-containing senescence-associated heterochromatin foci and senescence driven by ASF1a and HIRA

1 reference

https://pubmed.ncbi.nlm.nih.gov/30705777

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Ultrastructure of human embryonic stem cells and spontaneous and retinoic acid-induced differentiating cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/30705777

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Rescue of heterochromatin organization in Hutchinson-Gilford progeria by drug treatment

1 reference

https://pubmed.ncbi.nlm.nih.gov/30705777

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The Polycomb group gene Ezh2 prevents hematopoietic stem cell exhaustion

1 reference

https://pubmed.ncbi.nlm.nih.gov/30705777

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Global analysis of proliferation and cell cycle gene expression in the regulation of hematopoietic stem and progenitor cell fates

1 reference

https://pubmed.ncbi.nlm.nih.gov/30705777

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Reactive oxygen species act through p38 MAPK to limit the lifespan of hematopoietic stem cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/30705777

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mammalian Sir2 homolog SIRT7 is an activator of RNA polymerase I transcription

1 reference

https://pubmed.ncbi.nlm.nih.gov/30705777

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mutant nuclear lamin A leads to progressive alterations of epigenetic control in premature aging

1 reference

https://pubmed.ncbi.nlm.nih.gov/30705777

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Prolonged cell cycle transit is a defining and developmentally conserved hemopoietic stem cell property.

1 reference

https://pubmed.ncbi.nlm.nih.gov/30705777

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Sir2 represses endogenous polymerase II transcription units in the ribosomal DNA nontranscribed spacer

1 reference

https://pubmed.ncbi.nlm.nih.gov/30705777

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Differential impact of Ink4a and Arf on hematopoietic stem cells and their bone marrow microenvironment in Bmi1-deficient mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/30705777

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

pRB family proteins are required for H3K27 trimethylation and Polycomb repression complexes binding to and silencing p16INK4alpha tumor suppressor gene.

1 reference

https://pubmed.ncbi.nlm.nih.gov/30705777

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The Polycomb group proteins bind throughout the INK4A-ARF locus and are disassociated in senescent cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/30705777

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Bmi-1 is essential for the tumorigenicity of neuroblastoma cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/30705777

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

De novo DNA methyltransferase is essential for self-renewal, but not for differentiation, in hematopoietic stem cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/30705777

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Werner and Hutchinson-Gilford progeria syndromes: mechanistic basis of human progeroid diseases.

1 reference

https://pubmed.ncbi.nlm.nih.gov/30705777

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Genome-wide maps of chromatin state in pluripotent and lineage-committed cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/30705777

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Aging hematopoietic stem cells decline in function and exhibit epigenetic dysregulation

1 reference

https://pubmed.ncbi.nlm.nih.gov/30705777

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Increased polycomb-group oncogene Bmi-1 expression correlates with poor prognosis in hepatocellular carcinoma

1 reference

https://pubmed.ncbi.nlm.nih.gov/30705777

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Self-renewing osteoprogenitors in bone marrow sinusoids can organize a hematopoietic microenvironment

1 reference

https://pubmed.ncbi.nlm.nih.gov/30705777

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Pharmacogenetic analysis of lithium-induced delayed aging in Caenorhabditis elegans

1 reference

https://pubmed.ncbi.nlm.nih.gov/30705777

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Age-related changes in human bone marrow-derived mesenchymal stem cells: consequences for cell therapies

1 reference

https://pubmed.ncbi.nlm.nih.gov/30705777

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

SIRT6 is a histone H3 lysine 9 deacetylase that modulates telomeric chromatin

1 reference

https://pubmed.ncbi.nlm.nih.gov/30705777

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Global transcription in pluripotent embryonic stem cells.

1 reference

https://pubmed.ncbi.nlm.nih.gov/30705777

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Differential H3K4 methylation identifies developmentally poised hematopoietic genes

1 reference

https://pubmed.ncbi.nlm.nih.gov/30705777

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Stem cells and aging in the hematopoietic system

1 reference

https://pubmed.ncbi.nlm.nih.gov/30705777

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The clinical characteristics of Werner syndrome: molecular and biochemical diagnosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/30705777

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Impaired DNA damage response, genome instability, and tumorigenesis in SIRT1 mutant mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/30705777

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Large histone H3 lysine 9 dimethylated chromatin blocks distinguish differentiated from embryonic stem cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/30705777

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Conversion of 5-methylcytosine to 5-hydroxymethylcytosine in mammalian DNA by MLL partner TET1

1 reference

https://pubmed.ncbi.nlm.nih.gov/30705777

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Individuality and epigenetics in obesity.

1 reference

https://pubmed.ncbi.nlm.nih.gov/30705777

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Epigenetic landscaping during hESC differentiation to neural cells.

1 reference

https://pubmed.ncbi.nlm.nih.gov/30705777

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Histone H4 lysine 16 acetylation regulates cellular lifespan

1 reference

https://pubmed.ncbi.nlm.nih.gov/30705777

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The sirtuin SIRT6 deacetylates H3 K56Ac in vivo to promote genomic stability

1 reference

https://pubmed.ncbi.nlm.nih.gov/30705777

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

TWIST family of basic helix-loop-helix transcription factors mediate human mesenchymal stem cell growth and commitment

1 reference

https://pubmed.ncbi.nlm.nih.gov/30705777

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

DNA methyltransferase 1 is essential for and uniquely regulates hematopoietic stem and progenitor cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/30705777

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

DNA methylation protects hematopoietic stem cell multipotency from myeloerythroid restriction.

1 reference

https://pubmed.ncbi.nlm.nih.gov/30705777

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

DNA methylation pattern changes upon long-term culture and aging of human mesenchymal stromal cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/30705777

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Inhibitors of class 1 histone deacetylases reverse contextual memory deficits in a mouse model of Alzheimer's disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/30705777

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Polycomb Repressive Complex 2 and Trithorax modulate Drosophila longevity and stress resistance

1 reference

https://pubmed.ncbi.nlm.nih.gov/30705777

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Histone deacetylase controls adult stem cell aging by balancing the expression of polycomb genes and jumonji domain containing 3

1 reference

https://pubmed.ncbi.nlm.nih.gov/30705777

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Principles and challenges of genomewide DNA methylation analysis

1 reference

https://pubmed.ncbi.nlm.nih.gov/30705777

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identification of a common gene expression signature associated with immature clonal mesenchymal cell populations derived from bone marrow and dental tissues.

1 reference

https://pubmed.ncbi.nlm.nih.gov/30705777

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Distinct hematopoietic stem cell subtypes are differentially regulated by TGF-beta1.

1 reference

https://pubmed.ncbi.nlm.nih.gov/30705777

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Human aging-associated DNA hypermethylation occurs preferentially at bivalent chromatin domains

1 reference

https://pubmed.ncbi.nlm.nih.gov/30705777

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Functionally distinct hematopoietic stem cells modulate hematopoietic lineage potential during aging by a mechanism of clonal expansion

1 reference

https://pubmed.ncbi.nlm.nih.gov/30705777

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Epigenetic alterations in aging

1 reference

https://pubmed.ncbi.nlm.nih.gov/30705777

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Altered histone acetylation is associated with age-dependent memory impairment in mice.

1 reference

https://pubmed.ncbi.nlm.nih.gov/30705777

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Members of the H3K4 trimethylation complex regulate lifespan in a germline-dependent manner in C. elegans

1 reference

https://pubmed.ncbi.nlm.nih.gov/30705777

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Role of the polycomb group proteins in hematopoietic stem cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/30705777

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Protein deacetylation by sirtuins: delineating a post-translational regulatory program responsive to nutrient and redox stressors

1 reference

https://pubmed.ncbi.nlm.nih.gov/30705777

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Elevated Histone Expression Promotes Life Span Extension

1 reference

https://pubmed.ncbi.nlm.nih.gov/30705777

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Chromatin remodeling in the aging genome of Drosophila

1 reference

https://pubmed.ncbi.nlm.nih.gov/30705777

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Chromatin structure as a mediator of aging

1 reference

https://pubmed.ncbi.nlm.nih.gov/30705777

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Caloric restriction attenuates age-related changes of DNA methyltransferase 3a in mouse hippocampus.

1 reference

https://pubmed.ncbi.nlm.nih.gov/30705777

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Senescence-associated heterochromatin foci are dispensable for cellular senescence, occur in a cell type- and insult-dependent manner and follow expression of p16(ink4a).

1 reference

https://pubmed.ncbi.nlm.nih.gov/30705777

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Tet1 and Tet2 regulate 5-hydroxymethylcytosine production and cell lineage specification in mouse embryonic stem cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/30705777

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Genome-wide mapping of 5-hydroxymethylcytosine in embryonic stem cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/30705777

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

DNA methyltransferase controls stem cell aging by regulating BMI1 and EZH2 through microRNAs

1 reference

https://pubmed.ncbi.nlm.nih.gov/30705777

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Epigenetic dysregulation in mesenchymal stem cell aging and spontaneous differentiation

1 reference

https://pubmed.ncbi.nlm.nih.gov/30705777

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Tet2 loss leads to increased hematopoietic stem cell self-renewal and myeloid transformation

1 reference

https://pubmed.ncbi.nlm.nih.gov/30705777

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Histone H4 lysine 16 hypoacetylation is associated with defective DNA repair and premature senescence in Zmpste24-deficient mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/30705777

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Histone demethylase UTX-1 regulates C. elegans life span by targeting the insulin/IGF-1 signaling pathway

1 reference

https://pubmed.ncbi.nlm.nih.gov/30705777

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Deletion of Tet2 in mice leads to dysregulated hematopoietic stem cells and subsequent development of myeloid malignancies

1 reference

https://pubmed.ncbi.nlm.nih.gov/30705777

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The H3K27 demethylase UTX-1 regulates C. elegans lifespan in a germline-independent, insulin-dependent manner

1 reference

https://pubmed.ncbi.nlm.nih.gov/30705777

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Ten-Eleven-Translocation 2 (TET2) negatively regulates homeostasis and differentiation of hematopoietic stem cells in mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/30705777

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Evaluation of histone-modifying enzymes in stem cell populations

1 reference

https://pubmed.ncbi.nlm.nih.gov/30705777

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Age-related increase in levels of 5-hydroxymethylcytosine in mouse hippocampus is prevented by caloric restriction

1 reference

https://pubmed.ncbi.nlm.nih.gov/30705777

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Twist-1 induces Ezh2 recruitment regulating histone methylation along the Ink4A/Arf locus in mesenchymal stem cells.

1 reference

https://pubmed.ncbi.nlm.nih.gov/30705777

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Heterochromatin formation promotes longevity and represses ribosomal RNA synthesis

1 reference

https://pubmed.ncbi.nlm.nih.gov/30705777

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Stem cell heterogeneity: implications for aging and regenerative medicine

1 reference

https://pubmed.ncbi.nlm.nih.gov/30705777

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The histone demethylase Kdm3a is essential to progression through differentiation

1 reference

https://pubmed.ncbi.nlm.nih.gov/30705777

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Global heterochromatin loss: a unifying theory of aging?

1 reference

https://pubmed.ncbi.nlm.nih.gov/30705777

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Genome-scale DNA methylation pattern profiling of human bone marrow mesenchymal stem cells in long-term culture

1 reference

https://pubmed.ncbi.nlm.nih.gov/30705777

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Insufficient DNA methylation affects healthy aging and promotes age-related health problems

1 reference

https://pubmed.ncbi.nlm.nih.gov/30705777

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Independence of repressive histone marks and chromatin compaction during senescent heterochromatic layer formation

1 reference

https://pubmed.ncbi.nlm.nih.gov/30705777

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The role of mutations in epigenetic regulators in myeloid malignancies

1 reference

https://pubmed.ncbi.nlm.nih.gov/30705777

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Clonal evolution of preleukemic hematopoietic stem cells precedes human acute myeloid leukemia.

1 reference

https://pubmed.ncbi.nlm.nih.gov/30705777

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Functional roles of pluripotency transcription factors in mesenchymal stem cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/30705777

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The great unravelling: chromatin as a modulator of the aging process

1 reference

https://pubmed.ncbi.nlm.nih.gov/30705777

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Aging effects on DNA methylation modules in human brain and blood tissue

1 reference

https://pubmed.ncbi.nlm.nih.gov/30705777

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Ezh1 Is Required for Hematopoietic Stem Cell Maintenance and Prevents Senescence-like Cell Cycle Arrest

1 reference

https://pubmed.ncbi.nlm.nih.gov/30705777

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Dynamic chromatin remodeling mediated by polycomb proteins orchestrates pancreatic differentiation of human embryonic stem cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/30705777

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The histone demethylase UTX regulates stem cell migration and hematopoiesis

1 reference

https://pubmed.ncbi.nlm.nih.gov/30705777

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

SIRT3 reverses aging-associated degeneration

1 reference

https://pubmed.ncbi.nlm.nih.gov/30705777

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Proliferation-dependent alterations of the DNA methylation landscape underlie hematopoietic stem cell aging

1 reference

https://pubmed.ncbi.nlm.nih.gov/30705777

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Werner syndrome: a changing pattern of clinical manifestations in Japan (1917~2008).

1 reference

https://pubmed.ncbi.nlm.nih.gov/30705777

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The ageing haematopoietic stem cell compartment

1 reference

https://pubmed.ncbi.nlm.nih.gov/30705777

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Sirt1 ablation promotes stress-induced loss of epigenetic and genomic hematopoietic stem and progenitor cell maintenance

1 reference

https://pubmed.ncbi.nlm.nih.gov/30705777

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Chromatin remodeling, DNA damage repair and aging.

1 reference

https://pubmed.ncbi.nlm.nih.gov/30705777

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Transcriptional and epigenetic dynamics during specification of human embryonic stem cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/30705777

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

RNAi screen identifies Jarid1b as a major regulator of mouse HSC activity

1 reference

https://pubmed.ncbi.nlm.nih.gov/30705777

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Lamin B1 depletion in senescent cells triggers large-scale changes in gene expression and the chromatin landscape

1 reference

https://pubmed.ncbi.nlm.nih.gov/30705777

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

DNA methylation analysis of murine hematopoietic side population cells during aging

1 reference

https://pubmed.ncbi.nlm.nih.gov/30705777

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Sirt1 extends life span and delays aging in mice through the regulation of Nk2 homeobox 1 in the DMH and LH.

1 reference

https://pubmed.ncbi.nlm.nih.gov/30705777

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A methylome-wide study of aging using massively parallel sequencing of the methyl-CpG-enriched genomic fraction from blood in over 700 subjects

1 reference

https://pubmed.ncbi.nlm.nih.gov/30705777

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Chromatin modifiers and remodellers: regulators of cellular differentiation

1 reference

https://pubmed.ncbi.nlm.nih.gov/30705777

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Aging and epigenetic drift: a vicious cycle

1 reference

https://pubmed.ncbi.nlm.nih.gov/30705777

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

KDM5B focuses H3K4 methylation near promoters and enhancers during embryonic stem cell self-renewal and differentiation

1 reference

https://pubmed.ncbi.nlm.nih.gov/30705777

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identification of pre-leukaemic haematopoietic stem cells in acute leukaemia

1 reference

https://pubmed.ncbi.nlm.nih.gov/30705777

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Preleukemic mutations in human acute myeloid leukemia affect epigenetic regulators and persist in remission

1 reference

https://pubmed.ncbi.nlm.nih.gov/30705777

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Genome-wide age-related changes in DNA methylation and gene expression in human PBMCs.

1 reference

https://pubmed.ncbi.nlm.nih.gov/30705777

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Epigenomic profiling of young and aged HSCs reveals concerted changes during aging that reinforce self-renewal

1 reference

https://pubmed.ncbi.nlm.nih.gov/30705777

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Genome-wide analysis reveals DNA methylation markers that vary with both age and obesity

1 reference

https://pubmed.ncbi.nlm.nih.gov/30705777

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

D-beta-hydroxybutyrate extends lifespan in C. elegans

1 reference

https://pubmed.ncbi.nlm.nih.gov/30705777

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Dnmt3a and Dnmt3b have overlapping and distinct functions in hematopoietic stem cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/30705777

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

H3K4me1 marks DNA regions hypomethylated during aging in human stem and differentiated cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/30705777

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Age-related mutations associated with clonal hematopoietic expansion and malignancies

1 reference

https://pubmed.ncbi.nlm.nih.gov/30705777

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Clonal hematopoiesis and blood-cancer risk inferred from blood DNA sequence

1 reference

https://pubmed.ncbi.nlm.nih.gov/30705777

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Concise review: hematopoietic stem cell aging and the prospects for rejuvenation

1 reference

https://pubmed.ncbi.nlm.nih.gov/30705777

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Directed targeting of chromatin to the nuclear lamina is mediated by chromatin state and A-type lamins.

1 reference

https://pubmed.ncbi.nlm.nih.gov/30705777

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Aging stem cells. A Werner syndrome stem cell model unveils heterochromatin alterations as a driver of human aging

1 reference

https://pubmed.ncbi.nlm.nih.gov/30705777

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

SIRT6 safeguards human mesenchymal stem cells from oxidative stress by coactivating NRF2.

1 reference

https://pubmed.ncbi.nlm.nih.gov/30705777

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

DNA methylation in human epigenomes depends on local topology of CpG sites

1 reference

https://pubmed.ncbi.nlm.nih.gov/30705777

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Epigenetics of Aging

1 reference

https://pubmed.ncbi.nlm.nih.gov/30705777

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Age-associated hydroxymethylation in human bone-marrow mesenchymal stem cells.

1 reference

https://pubmed.ncbi.nlm.nih.gov/30705777

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Human blood cell levels of 5-hydroxymethylcytosine (5hmC) decline with age, partly related to acquired mutations in TET2.

1 reference

https://pubmed.ncbi.nlm.nih.gov/30705777

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Roles of H3K27me2 and H3K27me3 Examined during Fate Specification of Embryonic Stem Cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/30705777

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.14336/AD.2017.1213

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PubMed publication ID

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