A critical function for TGF-beta signaling in the development of natural CD4+CD25+Foxp3+ regulatory T cells (Q81157115)

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6 January 2020

title

A critical function for TGF-beta signaling in the development of natural CD4+CD25+Foxp3+ regulatory T cells (English)

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6 January 2020

5

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6 January 2020

author name string

Yongzhong Liu

1

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6 January 2020

Pin Zhang

2

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6 January 2020

Jun Li

3

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6 January 2020

Ashok B Kulkarni

4

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6 January 2020

Wanjun Chen

6

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6 January 2020

publication date

27 April 2008

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6 January 2020

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6 January 2020

volume

9

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6 January 2020

issue

6

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6 January 2020

page(s)

632-640

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Natural versus adaptive regulatory T cells

6 January 2020

cites work

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7 January 2021

A well adapted regulatory contrivance: regulatory T cell development and the forkhead family transcription factor Foxp3.

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7 January 2021

Treg cells: guardians for life

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7 January 2021

Regulatory T cells: key controllers of immunologic self-tolerance

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7 January 2021

Emerging challenges in regulatory T cell function and biology

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7 January 2021

Natural regulatory T cells and self-tolerance

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7 January 2021

CD4+ CD25+ suppressor T cells: more questions than answers

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7 January 2021

Mechanisms of suppression by suppressor T cells

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7 January 2021

Infectious tolerance and the long-term acceptance of transplanted tissue

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7 January 2021

Foxp3 programs the development and function of CD4+CD25+ regulatory T cells

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7 January 2021

Control of autoimmunity by naturally arising regulatory CD4+ T cells

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7 January 2021

An essential role for Scurfin in CD4+CD25+ T regulatory cells

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7 January 2021

Origin of regulatory T cells with known specificity for antigen

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7 January 2021

Thymic selection of CD4+CD25+ regulatory T cells induced by an agonist self-peptide

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7 January 2021

Number of T reg cells that differentiate does not increase upon encounter of agonist ligand on thymic epithelial cells.

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7 January 2021

Antigen-dependent proliferation of CD4+ CD25+ regulatory T cells in vivo

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7 January 2021

B7/CD28 costimulation is essential for the homeostasis of the CD4+CD25+ immunoregulatory T cells that control autoimmune diabetes

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7 January 2021

CD28 costimulation of developing thymocytes induces Foxp3 expression and regulatory T cell differentiation independently of interleukin 2.

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7 January 2021

Essential role for interleukin-2 for CD4(+)CD25(+) T regulatory cell development during the neonatal period

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7 January 2021

Development and function of agonist-induced CD25+Foxp3+ regulatory T cells in the absence of interleukin 2 signaling

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7 January 2021

A function for interleukin 2 in Foxp3-expressing regulatory T cells

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7 January 2021

Tolerance, not immunity, crucially depends on IL-2.

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7 January 2021

Transforming growth factor beta 1 null mutation in mice causes excessive inflammatory response and early death

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7 January 2021

Targeted disruption of the mouse transforming growth factor-beta 1 gene results in multifocal inflammatory disease

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7 January 2021

Reciprocal developmental pathways for the generation of pathogenic effector TH17 and regulatory T cells

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7 January 2021

Th3 cells in peripheral tolerance. II. TGF-beta-transgenic Th3 cells rescue IL-2-deficient mice from autoimmunity

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7 January 2021

Conversion of peripheral CD4+CD25- naive T cells to CD4+CD25+ regulatory T cells by TGF-beta induction of transcription factor Foxp3

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7 January 2021

Cutting Edge: IL-2 is essential for TGF-beta-mediated induction of Foxp3+ T regulatory cells

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7 January 2021

Cutting edge: TGF-beta induces a regulatory phenotype in CD4+CD25- T cells through Foxp3 induction and down-regulation of Smad7

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7 January 2021

TGF-beta induces Foxp3 + T-regulatory cells from CD4 + CD25 - precursors

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7 January 2021

Requirement of CD28 signaling in homeostasis/survival of TGF-beta converted CD4+CD25+ Tregs from thymic CD4+CD25- single positive T cells

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7 January 2021

Identifying Foxp3-expressing suppressor T cells with a bicistronic reporter

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7 January 2021

Natural and induced CD4+CD25+ cells educate CD4+CD25- cells to develop suppressive activity: the role of IL-2, TGF-beta, and IL-10.

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7 January 2021

Inducing and expanding regulatory T cell populations by foreign antigen

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7 January 2021

TGF-beta1 maintains suppressor function and Foxp3 expression in CD4+CD25+ regulatory T cells

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7 January 2021

T cells that cannot respond to TGF-beta escape control by CD4(+)CD25(+) regulatory T cells

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7 January 2021

Transforming growth factor-beta controls development, homeostasis, and tolerance of T cells by regulatory T cell-dependent and -independent mechanisms

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7 January 2021

Cellular mechanisms of fatal early-onset autoimmunity in mice with the T cell-specific targeting of transforming growth factor-beta receptor

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7 January 2021

T-cell-specific deletion of a polypeptide N-acetylgalactosaminyl-transferase gene by site-directed recombination

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7 January 2021

TGF-beta signaling-deficient hematopoietic stem cells have normal self-renewal and regenerative ability in vivo despite increased proliferative capacity in vitro

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7 January 2021

Autoimmune disease as a consequence of developmental abnormality of a T cell subpopulation

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7 January 2021

Developmental regulation of Foxp3 expression during ontogeny.

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7 January 2021

CD4+CD25+ immunoregulatory T cells suppress polyclonal T cell activation in vitro by inhibiting interleukin 2 production

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7 January 2021

Exclusion of circulating T cells from the thymus does not apply in the neonatal period

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7 January 2021

Clonal deletion of thymocytes by circulating dendritic cells homing to the thymus

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7 January 2021

Requirement for transforming growth factor beta1 in controlling T cell apoptosis

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7 January 2021

Mechanisms of TGF-beta signaling from cell membrane to the nucleus

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7 January 2021

Maternal rescue of transforming growth factor-beta 1 null mice

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7 January 2021

Transforming growth factor-beta regulation of immune responses

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7 January 2021

Nonredundant roles for Stat5a/b in directly regulating Foxp3

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7 January 2021

Early events in the thymus affect the balance of effector and regulatory T cells

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7 January 2021

Identifiers

DOI

10.1038/NI.1607

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6 January 2020

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