Protein phosphatase 2Calpha dephosphorylates axin and activates LEF-1-dependent transcription (Q22011145)

Protein phosphatase, Mg2+/Mn2+ dependent 1A

1 reference

Lymphoid enhancer binding factor 1

1 reference

Dishevelled segment polarity protein 3

1 reference

Wnt family member 1

1 reference

catenin beta 1

1 reference

canonical Wnt signaling pathway

1 reference

Journal of Biological Chemistry

E T Strovel

1

E T

Strovel

1 reference

7 February 2023

D Wu

series ordinal

2

author given names

D

author last names

Wu

1 reference

7 February 2023

D J Sussman

series ordinal

3

author given names

D J

author last names

Sussman

1 reference

7 February 2023

language of work or name

English

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publication date

28 January 2000

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published in

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volume

275

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page(s)

2399-403

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issue

4

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1 reference

https://api.crossref.org/works/10.1074%2FJBC.275.4.2399

WNTs modulate cell fate and behavior during vertebrate development

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.275.4.2399

Signal transduction by the Wnt family of ligands

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.275.4.2399

The mouse Fused locus encodes Axin, an inhibitor of the Wnt signaling pathway that regulates embryonic axis formation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.275.4.2399

Functional interaction of an axin homolog, conductin, with beta-catenin, APC, and GSK3beta

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.275.4.2399

Axin, a negative regulator of the wnt signaling pathway, directly interacts with adenomatous polyposis coli and regulates the stabilization of beta-catenin

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.275.4.2399

Axil, a member of the Axin family, interacts with both glycogen synthase kinase 3beta and beta-catenin and inhibits axis formation of Xenopus embryos

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.275.4.2399

Bridging of beta-catenin and glycogen synthase kinase-3beta by axin and inhibition of beta-catenin-mediated transcription

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.275.4.2399

Axin, a negative regulator of the Wnt signaling pathway, forms a complex with GSK-3beta and beta-catenin and promotes GSK-3beta-dependent phosphorylation of beta-catenin

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.275.4.2399

Functional interaction of beta-catenin with the transcription factor LEF-1

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.275.4.2399

Downregulation of beta-catenin by human Axin and its association with the APC tumor suppressor, beta-catenin and GSK3 beta

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.275.4.2399

The Drosophila segment polarity gene dishevelled encodes a novel protein required for response to the wingless signal

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.275.4.2399

Isolation and characterization of a mouse homolog of the Drosophila segment polarity gene dishevelled.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.275.4.2399

The dishevelled protein is modified by wingless signaling in Drosophila

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.275.4.2399

Analysis of Dishevelled signalling pathways during Xenopus development.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.275.4.2399

Differential recruitment of Dishevelled provides signaling specificity in the planar cell polarity and Wingless signaling pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.275.4.2399

Dishevelled activates JNK and discriminates between JNK pathways in planar polarity and wingless signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.275.4.2399

Dishevelled proteins lead to two signaling pathways. Regulation of LEF-1 and c-Jun N-terminal kinase in mammalian cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.275.4.2399

DIX domains of Dvl and axin are necessary for protein interactions and their ability to regulate beta-catenin stability

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.275.4.2399

Interaction of axin and Dvl-2 proteins regulates Dvl-2-stimulated TCF-dependent transcription.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.275.4.2399

Axin and Frat1 interact with dvl and GSK, bridging Dvl to GSK in Wnt-mediated regulation of LEF-1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.275.4.2399

Cdi1, a human G1 and S phase protein phosphatase that associates with Cdk2

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.275.4.2399

Phosphorylation of axin, a Wnt signal negative regulator, by glycogen synthase kinase-3beta regulates its stability

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.275.4.2399

Human beta-filamin is a new protein that interacts with the cytoplasmic tail of glycoprotein Ibalpha

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.275.4.2399

The structure and regulation of protein phosphatases

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.275.4.2399

Caenorhabditis elegans sex-determining protein FEM-2 is a protein phosphatase that promotes male development and interacts directly with FEM-3.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.275.4.2399

Wnt-mediated relocalization of dishevelled proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.275.4.2399

Characterization of mouse dishevelled (Dvl) proteins in Wnt/Wingless signaling pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.275.4.2399

Signal transduction through beta-catenin and specification of cell fate during embryogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.275.4.2399

Overexpression of the mouse dishevelled-1 protein inhibits GSK-3beta-mediated phosphorylation of tau in transfected mammalian cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.275.4.2399

Binding of GSK3beta to the APC-beta-catenin complex and regulation of complex assembly

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.275.4.2399

Inhibitory effect of a marine-sponge toxin, okadaic acid, on protein phosphatases. Specificity and kinetics

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.275.4.2399

The role of RhoA in tissue polarity and Frizzled signalling

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.275.4.2399

Protein phosphatase 2Calpha inhibits the human stress-responsive p38 and JNK MAPK pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.275.4.2399

Identification of a domain of Axin that binds to the serine/threonine protein phosphatase 2A and a self-binding domain

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.275.4.2399

Regulation of beta-catenin signaling by the B56 subunit of protein phosphatase 2A

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.275.4.2399

Serine/threonine protein phosphatases in the control of cell function

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.275.4.2399

inferred from DOI database lookup

7 January 2021

based on heuristic

Identifiers

DOI

10.1074/JBC.275.4.2399

0 references

Fatcat ID

release_2a37ipj5xrf65lo4vwe77ns4te

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/2a37ipj5xrf65lo4vwe77ns4te