tBid undergoes multiple conformational changes at the membrane required for Bax activation (Q24294675)

protein localization to mitochondrion

1 reference

BCL2-associated X protein

1 reference

BH3 interacting domain death agonist

1 reference

Mitochondrial carrier 2

1 reference

Clinton Campbell

5

0 references

David William Andrews

object named as

David W Andrews

8

0 references

author name string

Aisha Shamas-Din

1

0 references

Scott Bindner

2

0 references

Weijia Zhu

3

0 references

Yehudit Zaltsman

4

0 references

Atan Gross

6

0 references

Brian Leber

7

0 references

Cécile Fradin

Journal of Biological Chemistry

9

0 references

language of work or name

English

0 references

publication date

26 July 2013

0 references

published in

0 references

volume

288

0 references

issue

30

0 references

page(s)

22111-27

0 references

describes a project that uses

ImageJ

1 reference

Europe PubMed Central

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC3724664/fullTextXML

inferred from PubMed Central ID database lookup

cites work

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Caspase cleaved BID targets mitochondria and is required for cytochrome c release, while BCL-XL prevents this release but not tumor necrosis factor-R1/Fas death

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tBid elicits a conformational alteration in membrane-bound Bcl-2 such that it inhibits Bax pore formation

30 May 2018

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Interaction of the full-length Bax protein with biomimetic mitochondrial liposomes: a small-angle neutron scattering and fluorescence study.

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The Destabilization of Lipid Membranes Induced by the C-terminal Fragment of Caspase 8-cleaved Bid Is Inhibited by the N-terminal Fragment

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12 December 2020

Helix 6 of tBid is necessary but not sufficient for mitochondrial binding activity

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12 December 2020

A novel BH3-like domain in BID is required for intramolecular interaction and autoinhibition of pro-apoptotic activity

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12 December 2020

Conformational changes in BID, a pro-apoptotic BCL-2 family member, upon membrane binding. A site-directed spin labeling study

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12 December 2020

Mitochondria frozen with trehalose retain a number of biological functions and preserve outer membrane integrity

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12 December 2020

Fluorescence mapping of mitochondrial TIM23 complex reveals a water-facing, substrate-interacting helix surface

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12 December 2020