SIRT1 deacetylates and inhibits SREBP-1C activity in regulation of hepatic lipid metabolism (Q24298588)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20817729%20AND%20SRC:MED&resulttype=core&format=json

13 February 2020

title

SIRT1 deacetylates and inhibits SREBP-1C activity in regulation of hepatic lipid metabolism (English)

1 reference

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13 February 2020

0 references

1 reference

GOA release 2020-03-11

Sterol regulatory element binding transcription factor 1

1 reference

GOA release 2020-03-11

author

Mengwei Zang

6

1 reference

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13 February 2020

author name string

Bhaskar Ponugoti

1

1 reference

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13 February 2020

Dong-Hyun Kim

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20817729%20AND%20SRC:MED&resulttype=core&format=json

13 February 2020

Zhen Xiao

3

1 reference

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13 February 2020

Zachary Smith

4

1 reference

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13 February 2020

Ji Miao

5

1 reference

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13 February 2020

Shwu-Yuan Wu

7

1 reference

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13 February 2020

Cheng-Ming Chiang

8

1 reference

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13 February 2020

Timothy D Veenstra

9

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20817729%20AND%20SRC:MED&resulttype=core&format=json

13 February 2020

Jongsook Kim Kemper

10

1 reference

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13 February 2020

language of work or name

English

0 references

publication date

3 September 2010

1 reference

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13 February 2020

number of pages

12

1 reference

Journal of Biological Chemistry

inferred from page(s)

published in

1 reference

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13 February 2020

volume

285

1 reference

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13 February 2020

issue

44

1 reference

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13 February 2020

page(s)

33959-33970

1 reference

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describes a project that uses

13 February 2020

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC2962496/fullTextXML

inferred from PubMed Central ID database lookup

cites work

SIRT1 deacetylates and positively regulates the nuclear receptor LXR

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2962496

Sirtuin functions in health and disease

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2962496

Silent information regulator 2 potentiates Foxo1-mediated transcription through its deacetylase activity

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2962496

Peroxisome proliferator-activated receptor-gamma coactivator 1 alpha (PGC-1 alpha): transcriptional coactivator and metabolic regulator

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2962496

Sterol regulatory element binding protein 1a regulates hepatic fatty acid partitioning by activating acetyl coenzyme A carboxylase 2

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2962496

Salt-inducible kinase regulates hepatic lipogenesis by controlling SREBP-1c phosphorylation

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2962496

Functional interaction of hepatic nuclear factor-4 and peroxisome proliferator-activated receptor-gamma coactivator 1alpha in CYP7A1 regulation is inhibited by a key lipogenic activator, sterol regulatory element-binding protein-1c

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2962496

Resveratrol improves mitochondrial function and protects against metabolic disease by activating SIRT1 and PGC-1alpha

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2962496

Resveratrol improves health and survival of mice on a high-calorie diet

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2962496

Nutrient control of glucose homeostasis through a complex of PGC-1alpha and SIRT1

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2962496

SIRT1 functionally interacts with the metabolic regulator and transcriptional coactivator PGC-1{alpha}

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2962496

Sterol regulatory element-binding proteins (SREBPs): transcriptional regulators of lipid synthetic genes

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2962496

The SREBP pathway: regulation of cholesterol metabolism by proteolysis of a membrane-bound transcription factor

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2962496

PPARs and the complex journey to obesity

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2962496

Acetylation: a regulatory modification to rival phosphorylation?

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2962496

Conserved role of SIRT1 orthologs in fasting-dependent inhibition of the lipid/cholesterol regulator SREBP.

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2962496

FXR acetylation is normally dynamically regulated by p300 and SIRT1 but constitutively elevated in metabolic disease states

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2962496

Bile acid signaling pathways increase stability of Small Heterodimer Partner (SHP) by inhibiting ubiquitin-proteasomal degradation

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2962496

Hepatocyte-specific deletion of SIRT1 alters fatty acid metabolism and results in hepatic steatosis and inflammation.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2962496

The p300 acetylase is critical for ligand-activated farnesoid X receptor (FXR) induction of SHP.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2962496

Sirtuins in aging and disease

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2962496

Involvement of mammalian sirtuin 1 in the action of ethanol in the liver

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2962496

Metabolic adaptations through the PGC-1 alpha and SIRT1 pathways

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2962496

Fasting-dependent glucose and lipid metabolic response through hepatic sirtuin 1

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2962496

Coordinated recruitment of histone methyltransferase G9a and other chromatin-modifying enzymes in SHP-mediated regulation of hepatic bile acid metabolism

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2962496

Insulin regulation of cholesterol 7alpha-hydroxylase expression in human hepatocytes: roles of forkhead box O1 and sterol regulatory element-binding protein 1c.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2962496

Gene disruption by regulated short interfering RNA expression, using a two-adenovirus system.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2962496

Regulatory role of glycogen synthase kinase 3 for transcriptional activity of ADD1/SREBP1c

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2962496

Selective coactivator interactions in gene activation by SREBP-1a and -1c.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2962496

Role of an mSin3A-Swi/Snf chromatin remodeling complex in the feedback repression of bile acid biosynthesis by SHP.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2962496

Coactivator-dependent acetylation stabilizes members of the SREBP family of transcription factors.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2962496

Sterol regulatory element-binding proteins: transcriptional activators of lipid synthesis

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2962496

Sterol regulatory element-binding proteins (SREBPs): key regulators of nutritional homeostasis and insulin action

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2962496

Increased levels of nuclear SREBP-1c associated with fatty livers in two mouse models of diabetes mellitus

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2962496

Regulation of sterol regulatory element binding proteins in livers of fasted and refed mice

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2962496

Nutritional and insulin regulation of fatty acid synthetase and leptin gene expression through ADD1/SREBP1.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2962496

Isoform 1c of sterol regulatory element binding protein is less active than isoform 1a in livers of transgenic mice and in cultured cells

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2962496

Effects of diet and genetic background on sterol regulatory element-binding protein-1c, stearoyl-CoA desaturase 1, and the development of the metabolic syndrome

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2962496

A phosphorylation cascade controls the degradation of active SREBP1.

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2962496

Specific SIRT1 activation mimics low energy levels and protects against diet-induced metabolic disorders by enhancing fat oxidation

29 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2962496

Life-span extension in yeast.

29 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2962496

Control of lipid metabolism by phosphorylation-dependent degradation of the SREBP family of transcription factors by SCF(Fbw7).

29 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2962496

Sterol regulatory element-binding protein-1c mimics the negative effect of insulin on phosphoenolpyruvate carboxykinase (GTP) gene transcription

29 November 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/20817729

12 December 2020

inferred from PubMed ID database lookup

E6 oncoprotein represses p53-dependent gene activation via inhibition of protein acetylation independently of inducing p53 degradation

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/20817729

12 December 2020

inferred from PubMed ID database lookup

GCN5 acetyltransferase complex controls glucose metabolism through transcriptional repression of PGC-1alpha

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/20817729

12 December 2020

inferred from PubMed ID database lookup

Structural basis for double-stranded RNA processing by Dicer

1 reference

Crossref

https://api.crossref.org/works/10.1074%2FJBC.M110.122978

7 January 2021

inferred from DOI database lookup

Identifiers

DOI

10.1074/JBC.M110.122978

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20817729%20AND%20SRC:MED&resulttype=core&format=json

release_jhfau6ttijafdlhoz456rd6q64

13 February 2020

Fatcat ID

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/jhfau6ttijafdlhoz456rd6q64

24 November 2022

mapped directly with Wikidata item

1 reference

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20817729%20AND%20SRC:MED&resulttype=core&format=json

13 February 2020

2 references