Multiple tumor suppressor pathways negatively regulate telomerase (Q24306608)

MAX dimerization protein 1

1 reference

Zinc finger E-box binding homeobox 2

1 reference

MYC proto-oncogene, bHLH transcription factor

1 reference

sirtuin 1

1 reference

Microcephalin 1

1 reference

menin

1 reference

Fyn related Src family tyrosine kinase

1 reference

positive regulation of transcription by RNA polymerase II

1 reference

Menin interacts with the AP1 transcription factor JunD and represses JunD-activated transcription

2

Stephen J Elledge

Stephen J

Elledge

1 reference

9 December 2023

Shiaw Yih Lin

1

Shiaw Yih

Lin

1 reference

9 December 2023

language of work or name

English

0 references

publication date

27 June 2003

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published in

Cell

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volume

113

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issue

7

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page(s)

881-9

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cites work

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2803%2900430-6

7 January 2021

Telomerase regulation: not just flipping the switch

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2803%2900430-6

7 January 2021

Mice without telomerase: what can they teach us about human cancer?

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2803%2900430-6

7 January 2021

Mad proteins contain a dominant transcription repression domain.

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2803%2900430-6

7 January 2021

Mouse models to study the role of telomeres in cancer, aging and DNA repair

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2803%2900430-6

7 January 2021

Telomere shortening and tumor formation by mouse cells lacking telomerase RNA

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2803%2900430-6

7 January 2021

A system for stable expression of short interfering RNAs in mammalian cells

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2803%2900430-6

7 January 2021

Evidence for an alternative mechanism for maintaining telomere length in human tumors and tumor-derived cell lines

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2803%2900430-6

7 January 2021

Disruption of p53 in human cancer cells alters the responses to therapeutic agents

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2803%2900430-6

7 January 2021

Association between telomere length in blood and mortality in people aged 60 years or older

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2803%2900430-6

7 January 2021

The two-handed E box binding zinc finger protein SIP1 downregulates E-cadherin and induces invasion

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2803%2900430-6

7 January 2021

Human telomerase and its regulation

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2803%2900430-6

7 January 2021

Dissociation among in vitro telomerase activity, telomere maintenance, and cellular immortalization

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2803%2900430-6

7 January 2021

Activation of telomerase in a human tumor

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2803%2900430-6

7 January 2021

A biomarker that identifies senescent human cells in culture and in aging skin in vivo

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2803%2900430-6

7 January 2021

Regulation of the human telomerase reverse transcriptase gene

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2803%2900430-6

7 January 2021

Duplexes of 21-nucleotide RNAs mediate RNA interference in cultured mammalian cells

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2803%2900430-6

7 January 2021

Telomerase and differentiation in multicellular organisms: turn it off, turn it on, and turn it off again

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2803%2900430-6

7 January 2021

Telomere length regulation

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2803%2900430-6

7 January 2021

Telomerase activity, cell proliferation, and cancer

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2803%2900430-6

7 January 2021

The telomere terminal transferase of Tetrahymena is a ribonucleoprotein enzyme with two kinds of primer specificity

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2803%2900430-6

7 January 2021

Telomeres, telomerase and cancer

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2803%2900430-6

7 January 2021

Genetic pathways that regulate ageing in model organisms

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2803%2900430-6

7 January 2021

Telomerase activation, cellular immortalization and cancer

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2803%2900430-6

7 January 2021

Creation of human tumour cells with defined genetic elements

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2803%2900430-6

7 January 2021

The Hallmarks of Cancer

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2803%2900430-6

7 January 2021

The tumor suppressor protein menin interacts with NF-kappaB proteins and inhibits NF-kappaB-mediated transactivation

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2803%2900430-6

7 January 2021

Telomerase expression in human somatic cells does not induce changes associated with a transformed phenotype

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2803%2900430-6

7 January 2021

Specific association of human telomerase activity with immortal cells and cancer

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2803%2900430-6

7 January 2021

Complex regulatory mechanisms of telomerase activity in normal and cancer cells: how can we apply them for cancer therapy?

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2803%2900430-6

7 January 2021

Essential role of mouse telomerase in highly proliferative organs

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2803%2900430-6

7 January 2021

Genetic screens in mammalian cells by enhanced retroviral mutagens

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2803%2900430-6

7 January 2021

Inhibition of SV40 replication in simian cells by specific pBR322 DNA sequences

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2803%2900430-6

7 January 2021

Stem cells, telomerase and dyskeratosis congenita

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2803%2900430-6

7 January 2021

Multiple endocrine neoplasia type 1: clinical and genetic topics

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2803%2900430-6

7 January 2021

Telomeres and their control

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2803%2900430-6

7 January 2021

hEST2, the putative human telomerase catalytic subunit gene, is up-regulated in tumor cells and during immortalization

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2803%2900430-6

7 January 2021

Hypoxia extends the life span of vascular smooth muscle cells through telomerase activation.

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2803%2900430-6

7 January 2021

Absence of cancer-associated changes in human fibroblasts immortalized with telomerase

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2803%2900430-6

7 January 2021

Telomerase catalytic subunit homologs from fission yeast and human

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2803%2900430-6

7 January 2021

Identification of Mad as a repressor of the human telomerase (hTERT) gene

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2803%2900430-6

7 January 2021

Multiple pathways to cellular senescence: role of telomerase repressors

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2803%2900430-6

7 January 2021

Subsenescent telomere lengths in fibroblasts immortalized by limiting amounts of telomerase

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2803%2900430-6

7 January 2021

Longevity, Stress Response, and Cancer in Aging Telomerase-Deficient Mice

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2803%2900430-6

7 January 2021

Transfer of the human telomerase reverse transcriptase (TERT) gene into T lymphocytes results in extension of replicative potential.

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2803%2900430-6

7 January 2021

A survey of telomerase activity in human cancer

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2803%2900430-6

7 January 2021

Telomerase expression extends the proliferative life-span and maintains the osteogenic potential of human bone marrow stromal cells.

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2803%2900430-6

7 January 2021

p53 null mutations are associated with a telomerase negative phenotype in ovarian carcinoma

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2803%2900430-6

7 January 2021

Expression of the telomerase catalytic subunit, hTERT, induces resistance to transforming growth factor beta growth inhibition in p16INK4A(-) human mammary epithelial cells

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2803%2900430-6

7 January 2021

Telomerase and human tumorigenesis

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2803%2900430-6

7 January 2021

Senescence: does it all happen at the ends?

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2803%2900430-6

7 January 2021

Erosion of the telomeric single-strand overhang at replicative senescence

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2803%2900430-6

7 January 2021

Increased dosage of a sir-2 gene extends lifespan in Caenorhabditis elegans

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2803%2900430-6

7 January 2021

hSIR2(SIRT1) functions as an NAD-dependent p53 deacetylase

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2803%2900430-6

7 January 2021

The RNA component of telomerase is mutated in autosomal dominant dyskeratosis congenita

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2803%2900430-6

7 January 2021

Myc activates telomerase

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2803%2900430-6

7 January 2021

Telomere dysfunction and Atm deficiency compromises organ homeostasis and accelerates ageing

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2803%2900430-6

7 January 2021

Reversible cellular senescence: implications for immortalization of normal human diploid fibroblasts

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2803%2900430-6

7 January 2021

Downregulation of telomerase reverse transcriptase mRNA expression by wild type p53 in human tumor cells

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2803%2900430-6

7 January 2021

Switch from Myc/Max to Mad1/Max binding and decrease in histone acetylation at the telomerase reverse transcriptase promoter during differentiation of HL60 cells.

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2803%2900430-6

7 January 2021

Telomerase extends the lifespan of virus-transformed human cells without net telomere lengthening

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2803%2900430-6

7 January 2021