The FTLD risk factor TMEM106B and MAP6 control dendritic trafficking of lysosomes (Q24314869)

Microtubule associated protein 6

GOA release 2020-03-11

1 reference

GOA release 2020-03-11

dendrite morphogenesis

1 reference

GOA release 2020-03-11

10

Christian Haass

0 references

Stefan F Lichtenthaler

7

object named as

Stefan F Lichtenthaler

0 references

Dieter Edbauer

11

object named as

Dieter Edbauer

0 references

Anja Capell

9

object named as

Anja Capell

0 references

author name string

Benjamin M Schwenk

1

0 references

Christina M Lang

2

0 references

Sebastian Hogl

3

0 references

Sabina Tahirovic

4

0 references

Denise Orozco

5

0 references

Kristin Rentzsch

6

0 references

Casper C Hoogenraad

describes a project that uses

8

0 references

language of work or name

English

0 references

publication date

3 March 2014

0 references

published in

The EMBO Journal

0 references

volume

33

0 references

issue

5

0 references

page(s)

450-67

0 references

ImageJ

1 reference

Europe PubMed Central

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC3989627/fullTextXML

based on heuristic

inferred from PubMed Central ID database lookup

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Expanded GGGGCC hexanucleotide repeat in noncoding region of C9ORF72 causes chromosome 9p-linked FTD and ALS

19 March 2017

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The MAP2/Tau family of microtubule-associated proteins

19 March 2017

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A mutation in the vesicle-trafficking protein VAPB causes late-onset spinal muscular atrophy and amyotrophic lateral sclerosis

19 March 2017

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The suppression of brain cold-stable microtubules in mice induces synaptic defects associated with neuroleptic-sensitive behavioral disorders

19 March 2017

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Enhanced microtubule-dependent trafficking and p53 nuclear accumulation by suppression of microtubule dynamics

19 March 2017

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Rab-interacting lysosomal protein (RILP): the Rab7 effector required for transport to lysosomes.

19 March 2017

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Cloning, expression, and properties of the microtubule-stabilizing protein STOP

19 March 2017

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Regulation of synaptic structure and function by FMRP-associated microRNAs miR-125b and miR-132

19 March 2017

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TDP-43 mutations in familial and sporadic amyotrophic lateral sclerosis

19 March 2017

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Ubiquitinated TDP-43 in frontotemporal lobar degeneration and amyotrophic lateral sclerosis

19 March 2017

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Null mutations in progranulin cause ubiquitin-positive frontotemporal dementia linked to chromosome 17q21

19 March 2017

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STOP-like protein 21 is a novel member of the STOP family, revealing a Golgi localization of STOP proteins

19 March 2017

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Stable tubule only polypeptides (STOP) proteins co-aggregate with spheroid neurofilaments in amyotrophic lateral sclerosis

19 March 2017

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Impaired membrane resealing and autoimmune myositis in synaptotagmin VII-deficient mice

19 March 2017

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Plasma membrane repair is mediated by Ca(2+)-regulated exocytosis of lysosomes

19 March 2017

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In-gel digestion for mass spectrometric characterization of proteins and proteomes

19 March 2017

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A guided tour into subcellular colocalization analysis in light microscopy

7 April 2017

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Tracking the ends: a dynamic protein network controls the fate of microtubule tips

7 April 2017

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Dendritic organization in the neurons of the visual and motor cortices of the cat

7 April 2017

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Rab7: a key to lysosome biogenesis

7 April 2017

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Expression of TMEM106B, the frontotemporal lobar degeneration-associated protein, in normal and diseased human brain

7 April 2017

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3989627

TMEM106B p.T185S regulates TMEM106B protein levels: implications for frontotemporal dementia

27 September 2017

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Microtubule plus-ends within a mitotic cell are 'moving platforms' with anchoring, signalling and force-coupling roles.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3989627

TMEM106B, the risk gene for frontotemporal dementia, is regulated by the microRNA-132/212 cluster and affects progranulin pathways

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3989627

TMEM106B risk variant is implicated in the pathologic presentation of Alzheimer disease

27 September 2017

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Endocytic adaptor protein intersectin 1 forms a complex with microtubule stabilizer STOP in neurons.

27 September 2017

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Advances in understanding the molecular basis of frontotemporal dementia

27 September 2017

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Strikingly different clinicopathological phenotypes determined by progranulin-mutation dosage

27 September 2017

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3989627

Bmcc1s, a novel brain-isoform of Bmcc1, affects cell morphology by regulating MAP6/STOP functions

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3989627

Membrane orientation and subcellular localization of transmembrane protein 106B (TMEM106B), a major risk factor for frontotemporal lobar degeneration

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3989627

Endolysosomal sorting of ubiquitylated caveolin-1 is regulated by VCP and UBXD1 and impaired by VCP disease mutations

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3989627

The growth factor progranulin binds to TNF receptors and is therapeutic against inflammatory arthritis in mice

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3989627

TMEM106B is associated with frontotemporal lobar degeneration in a clinically diagnosed patient cohort

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3989627

Association of TMEM106B gene polymorphism with age at onset in granulin mutation carriers and plasma granulin protein levels

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3989627

TMEM106B regulates progranulin levels and the penetrance of FTLD in GRN mutation carriers.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3989627

Risk genotypes at TMEM106B are associated with cognitive impairment in amyotrophic lateral sclerosis

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3989627

Sortilin-mediated endocytosis determines levels of the frontotemporal dementia protein, progranulin.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3989627

Which way to go? Cytoskeletal organization and polarized transport in neurons

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3989627

Synapse loss in dementias

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3989627

Accelerated lipofuscinosis and ubiquitination in granulin knockout mice suggest a role for progranulin in successful aging

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3989627

Branching out: mechanisms of dendritic arborization

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3989627

Disruption of endocytic trafficking in frontotemporal dementia with CHMP2B mutations

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3989627

Common variants at 7p21 are associated with frontotemporal lobar degeneration with TDP-43 inclusions

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3989627

Valosin-containing protein (VCP) is required for autophagy and is disrupted in VCP disease

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3989627

Control of neuronal polarity and plasticity--a renaissance for microtubules?

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3989627

Roles of endosomal trafficking in neurite outgrowth and guidance

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3989627

Thin, stubby or mushroom: spine pathology in Alzheimer's disease

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3989627

Interactions between the juvenile Batten disease gene, CLN3, and the Notch and JNK signalling pathways.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3989627

Docking of axonal mitochondria by syntaphilin controls their mobility and affects short-term facilitation

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3989627

Functional multivesicular bodies are required for autophagic clearance of protein aggregates associated with neurodegenerative disease

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3989627

Defective lysosomal exocytosis and plasma membrane repair in Chediak-Higashi/beige cells.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3989627

The Rab7 effector protein RILP controls lysosomal transport by inducing the recruitment of dynein-dynactin motors

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3989627

Going new places using an old MAP: tau, microtubules and human neurodegenerative disease.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3989627

Mutant Rab7 causes the accumulation of cathepsin D and cation-independent mannose 6-phosphate receptor in an early endocytic compartment

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3989627

Dynein light chain LC8 regulates syntaphilin-mediated mitochondrial docking in axons

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3989627

Loss of fused in sarcoma (FUS) promotes pathological Tau splicing

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3989627

Growing dendrites and axons differ in their reliance on the secretory pathway

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3989627

Rab7 regulates transport from early to late endocytic compartments in Xenopus oocytes

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3989627

Phosphorylation of microtubule-associated protein STOP by calmodulin kinase II.

30 May 2018

1 reference

https://api.crossref.org/works/10.1002%2FEMBJ.201385857

The frontotemporal lobar degeneration risk factor, TMEM106B, regulates lysosomal morphology and function

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEMBJ.201385857

Distance to Nearest Neighbor as a Measure of Spatial Relationships in Populations

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEMBJ.201385857

Both chronic treatments by epothilone D and fluoxetine increase the short-term memory and differentially alter the mood status of STOP/MAP6 KO mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEMBJ.201385857

Polarized secretory trafficking directs cargo for asymmetric dendrite growth and morphogenesis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEMBJ.201385857

Synaptic dysfunction in progranulin-deficient mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEMBJ.201385857

Cellular ageing, increased mortality and FTLD-TDP-associated neuropathology in progranulin knockout mice

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3989627

29 November 2018

Identifiers

DOI

10.1002/EMBJ.201385857

1 reference

1 reference

1 reference

PubMed publication ID

24357581

1 reference