Structural insights into RNA processing by the human RISC-loading complex (Q24324404)

TARBP2 subunit of RISC loading complex

GOA release 2020-03-11

1 reference

Argonaute RISC catalytic component 2

GOA release 2020-03-11

1 reference

GOA release 2020-03-11

author

Jennifer Doudna

7

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Eva Nogales

8

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David W Taylor

object named as

David W Taylor

4

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author name string

Hong-Wei Wang

1

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Cameron Noland

2

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Bunpote Siridechadilok

3

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Enbo Ma

5

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Karin Felderer

Nature Structural & Molecular Biology

6

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language of work or name

English

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publication date

November 2009

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published in

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volume

16

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issue

11

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page(s)

1148-53

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on focus list of Wikimedia project

ScienceSource

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cites work

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In vitro reconstitution of the human RISC-loading complex

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Human TRBP and PACT directly interact with each other and associate with dicer to facilitate the production of small interfering RNA

19 March 2017

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The role of PACT in the RNA silencing pathway

19 March 2017

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TRBP, a regulator of cellular PKR and HIV-1 virus expression, interacts with Dicer and functions in RNA silencing

19 March 2017

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TRBP recruits the Dicer complex to Ago2 for microRNA processing and gene silencing

19 March 2017

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Structure of an argonaute silencing complex with a seed-containing guide DNA and target RNA duplex

19 March 2017

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Structure of the guide-strand-containing argonaute silencing complex

19 March 2017

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Asymmetry in the assembly of the RNAi enzyme complex

19 March 2017

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Role for a bidentate ribonuclease in the initiation step of RNA interference

19 March 2017

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19 March 2017

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Passenger-strand cleavage facilitates assembly of siRNA into Ago2-containing RNAi enzyme complexes

19 March 2017

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Evolutionary conservation of a unique amino acid sequence in human DICER protein essential for binding to Argonaute family proteins

19 March 2017

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Structural basis for double-stranded RNA processing by Dicer

19 March 2017

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Purified Argonaute2 and an siRNA form recombinant human RISC

19 March 2017

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Crystal structure of conserved domains 1 and 2 of the human DEAD-box helicase DDX3X in complex with the mononucleotide AMP

19 March 2017

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Crystal structure of Argonaute and its implications for RISC slicer activity

22 April 2017

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Illuminating the silence: understanding the structure and function of small RNAs

7 April 2017

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Structure of the anaphase-promoting complex/cyclosome interacting with a mitotic checkpoint complex

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27 September 2017

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A potential protein-RNA recognition event along the RISC-loading pathway from the structure of A. aeolicus Argonaute with externally bound siRNA.

27 September 2017

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Short interfering RNA strand selection is independent of dsRNA processing polarity during RNAi in Drosophila

27 September 2017

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Argonaute2 cleaves the anti-guide strand of siRNA during RISC activation

27 September 2017

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Crystal structure of A. aeolicus argonaute, a site-specific DNA-guided endoribonuclease, provides insights into RISC-mediated mRNA cleavage

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2845538

A protein sensor for siRNA asymmetry

27 September 2017

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Using situs for flexible and rigid-body fitting of multiresolution single-molecule data

27 September 2017

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Three-dimensional reconstruction from a single-exposure, random conical tilt series applied to the 50S ribosomal subunit of Escherichia coli

27 September 2017

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27 September 2017

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21 January 2018

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The ribosome at improved resolution: new techniques for merging and orientation refinement in 3D cryo-electron microscopy of biological particles

30 May 2018

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Structural determinants of RNA recognition and cleavage by Dicer

30 May 2018

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Disentangling conformational states of macromolecules in 3D-EM through likelihood optimization.

21 January 2018

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Dynamics of EF-G interaction with the ribosome explored by classification of a heterogeneous cryo-EM dataset

21 January 2018

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31 March 2020

Identifiers

DOI

10.1038/NSMB.1673

1 reference

Dimensions Publication ID

1003085478

0 references

1 reference

1 reference

PubMed publication ID

19820710

1 reference