Fbxw7 acts as an E3 ubiquitin ligase that targets c-Myb for nemo-like kinase (NLK)-induced degradation (Q24651352)

2

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Tsuyoshi Takagi

3

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Nobumoto Watanabe

4

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Keiichi I Nakayama

5

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Shunsuke Ishii

Journal of Biological Chemistry

6

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language of work or name

English

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publication date

7 November 2008

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published in

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volume

283

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issue

45

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page(s)

30540-8

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cites work

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The homeobox gene GBX2, a target of the myb oncogene, mediates autocrine growth and monocyte differentiation

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Structural basis for phosphodependent substrate selection and orientation by the SCFCdc4 ubiquitin ligase

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TRAF7 sequesters c-Myb to the cytoplasm by stimulating its sumoylation

7 April 2017

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Regulation of the cell cycle by SCF-type ubiquitin ligases

7 April 2017

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The ubiquitin ligase SCFFbw7 antagonizes apoptotic JNK signaling

7 April 2017

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Multisite phosphorylation by Cdk2 and GSK3 controls cyclin E degradation

7 April 2017

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Multisite phosphorylation of a CDK inhibitor sets a threshold for the onset of DNA replication

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Human F-box protein hCdc4 targets cyclin E for proteolysis and is mutated in a breast cancer cell line

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Archipelago regulates Cyclin E levels in Drosophila and is mutated in human cancer cell lines

7 April 2017

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The SCFFBW7 ubiquitin ligase complex as a tumor suppressor in T cell leukemia

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Duplication of the MYB oncogene in T cell acute lymphoblastic leukemia

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28 September 2017

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The Wnt-NLK signaling pathway inhibits A-Myb activity by inhibiting the association with coactivator CBP and methylating histone H3.

28 September 2017

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28 September 2017

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28 September 2017

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28 September 2017

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28 September 2017

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28 September 2017

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28 September 2017

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Transcriptional activation of the c-myc gene by the c-myb and B-myb gene products

28 September 2017

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Transactivation and transformation by Myb are negatively regulated by a leucine-zipper structure

28 September 2017

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v-Myb of E26 leukemia virus up-regulates bcl-2 and suppresses apoptosis in myeloid cells

28 September 2017

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Turnover of cyclin E by the ubiquitin-proteasome pathway is regulated by cdk2 binding and cyclin phosphorylation

30 May 2018

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30 May 2018

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Oncogenic activation of c-Myb correlates with a loss of negative regulation by TIF1beta and Ski.

21 January 2018

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A nucleolar isoform of the Fbw7 ubiquitin ligase regulates c-Myc and cell size

21 January 2018

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Recognition of phosphodegron motifs in human cyclin E by the SCF(Fbw7) ubiquitin ligase

21 January 2018

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Fbxw7/Cdc4 is a p53-dependent, haploinsufficient tumour suppressor gene

21 January 2018

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In vitro reconstitution of SCF substrate ubiquitination with purified proteins

21 January 2018

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Increased affinity of c-Myb for CREB-binding protein (CBP) after CBP-induced acetylation

21 January 2018

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Context of multiubiquitin chain attachment influences the rate of Sic1 degradation

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CBP as a transcriptional coactivator of c-Myb

21 January 2018

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https://pubmed.ncbi.nlm.nih.gov/18765672