Mutant p53 attenuates the SMAD-dependent transforming growth factor beta1 (TGF-beta1) signaling pathway by repressing the expression of TGF-beta receptor type II (Q24681272)

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English	Mutant p53 attenuates the SMAD-dependent transforming growth factor beta1 (TGF-beta1) signaling pathway by repressing the expression of TGF-beta receptor type II	scientific article

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Mutant p53 attenuates the SMAD-dependent transforming growth factor beta1 (TGF-beta1) signaling pathway by repressing the expression of TGF-beta receptor type II (English)

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9

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Varda Rotter

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author name string

Eyal Kalo

1

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Yosef Buganim

2

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Keren E Shapira

3

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Hilla Besserglick

4

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Naomi Goldfinger

5

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Lilach Weisz

6

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Perry Stambolsky

7

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Yoav I Henis

8

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December 2007

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Molecular and Cellular Biology

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27

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23

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8228-42

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Europe PubMed Central

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC2169171/fullTextXML

based on heuristic

inferred from PubMed Central ID database lookup

TGF-beta signal transduction

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2169171

7 April 2017

Dual role of the Smad4/DPC4 tumor suppressor in TGFbeta-inducible transcriptional complexes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2169171

7 April 2017

TGF beta signals through a heteromeric protein kinase receptor complex

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2169171

7 April 2017

Surfing the p53 network

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2169171

7 April 2017

TGF-beta signalling from cell membrane to nucleus through SMAD proteins

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2169171

7 April 2017

Repression of the MSP/MST-1 gene contributes to the antiapoptotic gain of function of mutant p53

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2169171

7 April 2017

Smad-dependent and Smad-independent pathways in TGF-beta family signalling

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2169171

7 April 2017

Integrity of the N-terminal transcription domain of p53 is required for mutant p53 interference with drug-induced apoptosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2169171

7 April 2017

Controlling TGF-beta signaling

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2169171

7 April 2017

Mechanism of activation of the TGF-beta receptor

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2169171

7 April 2017

How cells read TGF-beta signals

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2169171

7 April 2017

Transcriptional control by the TGF-beta/Smad signaling system

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2169171

7 April 2017

Direct binding of Smad3 and Smad4 to critical TGF beta-inducible elements in the promoter of human plasminogen activator inhibitor-type 1 gene

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2169171

7 April 2017

Wound healing--aiming for perfect skin regeneration

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2169171

7 April 2017

Transcription regulation by mutant p53.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2169171

28 September 2017

Integration of TGF-beta and Ras/MAPK signaling through p53 phosphorylation.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2169171

28 September 2017

Mutant p53 protects cells from 12-O-tetradecanoylphorbol-13-acetate-induced death by attenuating activating transcription factor 3 induction

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2169171

28 September 2017

Clustering of raft-associated proteins in the external membrane leaflet modulates internal leaflet H-ras diffusion and signaling

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2169171

28 September 2017

Transactivation of the EGR1 gene contributes to mutant p53 gain of function

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2169171

28 September 2017

Transcriptional activities of mutant p53: when mutations are more than a loss

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2169171

28 September 2017

Matrix metalloproteinase inhibitor GM 6001 attenuates keratinocyte migration, contraction and myofibroblast formation in skin wounds

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2169171

28 September 2017

Mutant p53 exerts a dominant negative effect by preventing wild-type p53 from binding to the promoter of its target genes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2169171

28 September 2017

The p53 saga: the good, the bad, and the dead

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2169171

28 September 2017

Links between tumor suppressors: p53 is required for TGF-beta gene responses by cooperating with Smads.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2169171

28 September 2017

Decision making by p53: life, death and cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2169171

28 September 2017

Transforming growth factor-beta1 modulates matrix metalloproteinase-9 production through the Ras/MAPK signaling pathway in transformed keratinocytes.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2169171

28 September 2017

The effects of wild-type p53 tumor suppressor activity and mutant p53 gain-of-function on cell growth

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2169171

28 September 2017

Mutant p53 cooperates with ETS and selectively up-regulates human MDR1 not MRP1.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2169171

28 September 2017

Oncogenic mutations of the p53 tumor suppressor: the demons of the guardian of the genome.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2169171

28 September 2017

Inactivation of the transforming growth factor beta type II receptor in human small cell lung cancer cell lines

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2169171

28 September 2017

Activation of c-myc gene expression by tumor-derived p53 mutants requires a discrete C-terminal domain

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2169171

28 September 2017

Tumor suppressor Smad4 is a transforming growth factor beta-inducible DNA binding protein

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2169171

28 September 2017

TbetaRI phosphorylation of Smad2 on Ser465 and Ser467 is required for Smad2-Smad4 complex formation and signaling

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2169171

28 September 2017

Resistance of human squamous carcinoma cells to transforming growth factor beta 1 is a recessive trait

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2169171

28 September 2017

Resistance to inhibition of cell growth by transforming growth factor-beta and its role in oncogenesis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2169171

28 September 2017

The types II and III transforming growth factor-beta receptors form homo-oligomers

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2169171

28 September 2017

Mutant p53 can induce tumorigenic conversion of human bronchial epithelial cells and reduce their responsiveness to a negative growth factor, transforming growth factor beta 1

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2169171

28 September 2017

A single internalization signal from the di-leucine family is critical for constitutive endocytosis of the type II TGF-beta receptor

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2169171

30 May 2018

Gain of function mutations in p53.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2169171

30 May 2018

Mutant p53 tumor suppressor gene causes resistance to transforming growth factor beta 1 in murine keratinocytes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2169171

30 May 2018

Reconstitution of p53 expression in a nonproducer Ab-MuLV-transformed cell line by transfection of a functional p53 gene.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2169171

30 May 2018

Tumor suppressor p53: analysis of wild-type and mutant p53 complexes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2169171

30 May 2018

Correlated abnormalities of transforming growth factor-β1 response and p53 expression in thyroid epithelial cell transformation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2169171

30 May 2018

Gain of function of a p53 hot spot mutation in a mouse model of Li-Fraumeni syndrome.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2169171

28 November 2018

Nerve growth factor mediates activation of the Smad pathway in PC12 cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2169171

28 November 2018

p53 and TGF-beta in development: prelude to tumor suppression?

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2169171

28 November 2018

Mutant p53 gain of function: repression of CD95(Fas/APO-1) gene expression by tumor-associated p53 mutants

1 reference

https://pubmed.ncbi.nlm.nih.gov/17875924

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

WAF1/CIP1 is induced in p53-mediated G1 arrest and apoptosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/17875924

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Specific P53 mutations are associated with de novo resistance to doxorubicin in breast cancer patients

1 reference

https://pubmed.ncbi.nlm.nih.gov/17875924

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Frequent inactivation of the transforming growth factor beta type II receptor in small-cell lung carcinoma cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/17875924

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mutant p53 gain of function: differential effects of different p53 mutants on resistance of cultured cells to chemotherapy

1 reference

https://pubmed.ncbi.nlm.nih.gov/17875924

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mutant p53 gain of function in two mouse models of Li-Fraumeni syndrome

1 reference

https://pubmed.ncbi.nlm.nih.gov/17875924

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The effects of a mutant p53 protein on the proliferation and differentiation of PC12 rat phaeochromocytoma cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/17875924

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

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