Irradiation specifically sensitises solid tumour cell lines to TRAIL mediated apoptosis (Q24798681)

1

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Angelika Schmid

2

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Verena Jendrossek

3

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Heidrun Faltin

4

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Peter T Daniel

5

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Wilfried Budach

BH4 domain of antiapoptotic Bcl-2 family members closes voltage-dependent anion channel and inhibits apoptotic mitochondrial changes and cell death

6

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language of work or name

English

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publication date

14 January 2005

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published in

BMC Cancer

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volume

5

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issue

1

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page(s)

5

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cites work

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The novel receptor TRAIL-R4 induces NF-kappaB and protects against TRAIL-mediated apoptosis, yet retains an incomplete death domain

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FADD, a novel death domain-containing protein, interacts with the death domain of Fas and initiates apoptosis

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A unique zinc-binding site revealed by a high-resolution X-ray structure of homotrimeric Apo2L/TRAIL

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Death receptor recruitment of endogenous caspase-10 and apoptosis initiation in the absence of caspase-8

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TRAIL receptor-2 signals apoptosis through FADD and caspase-8

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Temperature-sensitive differential affinity of TRAIL for its receptors. DR5 is the highest affinity receptor

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Tumor necrosis factor-related apoptosis-inducing ligand receptors signal NF-kappaB and JNK activation and apoptosis through distinct pathways

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TRUNDD, a new member of the TRAIL receptor family that antagonizes TRAIL signalling

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A novel receptor for Apo2L/TRAIL contains a truncated death domain

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Identification and molecular cloning of two novel receptors for the cytotoxic ligand TRAIL

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TRICK2, a new alternatively spliced receptor that transduces the cytotoxic signal from TRAIL

7 April 2017

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Control of TRAIL-induced apoptosis by a family of signaling and decoy receptors

7 April 2017

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An antagonist decoy receptor and a death domain-containing receptor for TRAIL

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FLICE, a novel FADD-homologous ICE/CED-3-like protease, is recruited to the CD95 (Fas/APO-1) death--inducing signaling complex

7 April 2017

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p53-dependent apoptosis modulates the cytotoxicity of anticancer agents

7 April 2017

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Type I and type II reactions in TRAIL-induced apoptosis -- results from dose-response studies.

7 April 2017

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Multidomain Bcl-2 homolog Bax but not Bak mediates synergistic induction of apoptosis by TRAIL and 5-FU through the mitochondrial apoptosis pathway

28 September 2017

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Ionizing radiation enhances the therapeutic potential of TRAIL in prostate cancer in vitro and in vivo: Intracellular mechanisms

28 September 2017

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DNA damage-induced apoptosis

28 September 2017

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Guardians of cell death: the Bcl-2 family proteins

28 September 2017

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Apoptosis induction in renal cell carcinoma by TRAIL and gamma-radiation is impaired by deficient caspase-9 cleavage

28 September 2017

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Apo2L/TRAIL and its death and decoy receptors

28 September 2017

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Chemotherapy: targeting the mitochondrial cell death pathway

28 September 2017

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28 September 2017

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Chemotherapeutic agents sensitize osteogenic sarcoma cells, but not normal human bone cells, to Apo2L/TRAIL-induced apoptosis.

28 September 2017

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Potential and caveats of TRAIL in cancer therapy

28 September 2017

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Critical role for tumor necrosis factor-related apoptosis-inducing ligand in immune surveillance against tumor development

28 September 2017

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TRAIL/Apo-2L: mechanisms and clinical applications in cancer

28 September 2017

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Adriamycin sensitizes the adriamycin-resistant 8226/Dox40 human multiple myeloma cells to Apo2L/tumor necrosis factor-related apoptosis-inducing ligand-mediated (TRAIL) apoptosis.

28 September 2017

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28 September 2017

Is TRAIL hepatotoxic?

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Activation of caspase-8 in drug-induced apoptosis of B-lymphoid cells is independent of CD95/Fas receptor-ligand interaction and occurs downstream of caspase-3.

28 September 2017

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Pretreatment with paclitaxel enhances apo-2 ligand/tumor necrosis factor-related apoptosis-inducing ligand-induced apoptosis of prostate cancer cells by inducing death receptors 4 and 5 protein levels.

28 September 2017

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Combined effect of tumor necrosis factor-related apoptosis-inducing ligand and ionizing radiation in breast cancer therapy

28 September 2017

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Apaf1 and the apoptotic machinery

28 September 2017

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Safety and antitumor activity of recombinant soluble Apo2 ligand

28 September 2017

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Tumoricidal activity of tumor necrosis factor-related apoptosis-inducing ligand in vivo.

28 September 2017

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Bcl-xL regulates apoptosis by heterodimerization-dependent and -independent mechanisms

28 September 2017

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Osteoprotegerin is a receptor for the cytotoxic ligand TRAIL.

28 September 2017

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Increased death receptor 5 expression by chemotherapeutic agents in human gliomas causes synergistic cytotoxicity with tumor necrosis factor-related apoptosis-inducing ligand in vitro and in vivo

28 September 2017

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A Method for Testing for Synergy with Any Number of Agents

30 May 2018

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Increased susceptibility to tumor initiation and metastasis in TNF-related apoptosis-inducing ligand-deficient mice

30 May 2018

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Molecular requirements for the combined effects of TRAIL and ionising radiation

21 January 2018

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Synergistic induction of apoptosis by the combination of trail and chemotherapy in chemoresistant ovarian cancer cells.

21 January 2018

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Chemotherapeutic agents enhance TRAIL-induced apoptosis in prostate cancer cells

21 January 2018

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Tumor necrosis factor-related apoptosis-inducing ligand cooperates with anticancer drugs to overcome chemoresistance in antiapoptotic Bcl-2 family members expressing jurkat cells.

21 January 2018

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Intracellular regulation of tumor necrosis factor-related apoptosis-inducing ligand-induced apoptosis in human multiple myeloma cells

21 January 2018

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Effects of sequential treatments with chemotherapeutic drugs followed by TRAIL on prostate cancer in vitro and in vivo

21 January 2018

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The sequential treatment with ionizing radiation followed by TRAIL/Apo-2L reduces tumor growth and induces apoptosis of breast tumor xenografts in nude mice

28 November 2018

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Synergistic interactions of chemotherapeutic drugs and tumor necrosis factor-related apoptosis-inducing ligand/Apo-2 ligand on apoptosis and on regression of breast carcinoma in vivo

28 November 2018

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Celecoxib activates a novel mitochondrial apoptosis signaling pathway

28 November 2018

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Differential roles of RelA (p65) and c-Rel subunits of nuclear factor kappa B in tumor necrosis factor-related apoptosis-inducing ligand signaling.

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p53-dependent and -independent regulation of the death receptor KILLER/DR5 gene expression in response to genotoxic stress and tumor necrosis factor alpha

28 November 2018

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12 December 2020

Death by a thousand cuts: an ever increasing list of caspase substrates

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12 December 2020

Bcl-xL prevents cell death following growth factor withdrawal by facilitating mitochondrial ATP/ADP exchange

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12 December 2020

Differential role of caspase-8 and BID activation during radiation- and CD95-induced apoptosis

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12 December 2020

Apoptosis induced in normal human hepatocytes by tumor necrosis factor-related apoptosis-inducing ligand

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12 December 2020

Caspase-8/FLICE functions as an executioner caspase in anticancer drug-induced apoptosis

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12 December 2020

Augmentation of tumor necrosis factor-related apoptosis-inducing ligand (TRAIL)-induced apoptosis by the synthetic retinoid 6-[3-(1-adamantyl)-4-hydroxyphenyl]-2-naphthalene carboxylic acid (CD437) through up-regulation of TRAIL receptors in human l

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12 December 2020

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Regulation of death receptor expression and TRAIL/Apo2L-induced apoptosis by NF-kappaB

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12 December 2020

Ionizing radiation sensitizes erythroleukemic cells but not normal erythroblasts to tumor necrosis factor-related apoptosis-inducing ligand (TRAIL)-mediated cytotoxicity by selective up-regulation of TRAIL-R1

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Sensitization of resistant lymphoma cells to irradiation-induced apoptosis by the death ligand TRAIL

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12 December 2020