Functions of the 19S complex in proteasomal degradation (Q26996345)

Crossref

Andrew D. Jacobson

series ordinal

2

1 reference

Crossref

language of work or name

1 reference

February 2013

1 reference

Trends in Biochemical Sciences

published in

1 reference

volume

38

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issue

2

1 reference

page(s)

103-10

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The proteasomal de-ubiquitinating enzyme POH1 promotes the double-strand DNA break response

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Regulation and cellular roles of ubiquitin-specific deubiquitinating enzymes

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Quantitative proteomics reveals the function of unconventional ubiquitin chains in proteasomal degradation

21 March 2017

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Distinct modes of regulation of the Uch37 deubiquitinating enzyme in the proteasome and in the Ino80 chromatin-remodeling complex

21 March 2017

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Relative structural and functional roles of multiple deubiquitylating proteins associated with mammalian 26S proteasome

21 March 2017

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Regulation of Pax3 by proteasomal degradation of monoubiquitinated protein in skeletal muscle progenitors

21 March 2017

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A ubiquitin ligase transfers preformed polyubiquitin chains from a conjugating enzyme to a substrate

21 March 2017

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hRpn13/ADRM1/GP110 is a novel proteasome subunit that binds the deubiquitinating enzyme, UCH37

21 March 2017

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A novel proteasome interacting protein recruits the deubiquitinating enzyme UCH37 to 26S proteasomes

21 March 2017

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Sem1p is a novel subunit of the 26 S proteasome from Saccharomyces cerevisiae

21 March 2017

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MPN+, a putative catalytic motif found in a subset of MPN domain proteins from eukaryotes and prokaryotes, is critical for Rpn11 function

21 March 2017

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The ubiquitin-proteasome proteolytic pathway: destruction for the sake of construction

21 March 2017

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Recognition of the polyubiquitin proteolytic signal

21 March 2017

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Interaction of hHR23 with S5a. The ubiquitin-like domain of hHR23 mediates interaction with S5a subunit of 26 S proteasome

21 March 2017

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Structure of Proteasome Ubiquitin Receptor hRpn13 and Its Activation by the Scaffolding Protein hRpn2

21 March 2017

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Structure of the S5a:K48-Linked Diubiquitin Complex and Its Interactions with Rpn13

21 March 2017

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Structural Insights into the Regulatory Particle of the Proteasome from Methanocaldococcus jannaschii

21 March 2017

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Ubiquitin docking at the proteasome through a novel pleckstrin-homology domain interaction

21 March 2017

1 reference

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Proteasome subunit Rpn13 is a novel ubiquitin receptor

21 March 2017

1 reference

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Structural basis for the activation of 20S proteasomes by 11S regulators

21 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3557657

Structure of 20S proteasome from yeast at 2.4 A resolution

21 March 2017

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3557657

RING domain E3 ubiquitin ligases

21 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3557657

Lysine 63-linked polyubiquitin chain may serve as a targeting signal for the 26S proteasome

21 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3557657

Deubiquitinating enzyme Ubp6 functions noncatalytically to delay proteasomal degradation.

21 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3557657

Complementary roles for Rpn11 and Ubp6 in deubiquitination and proteolysis by the proteasome

21 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3557657

Multiple associated proteins regulate proteasome structure and function

21 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3557657

A cryptic protease couples deubiquitination and degradation by the proteasome

21 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3557657

Role of Rpn11 metalloprotease in deubiquitination and degradation by the 26S proteasome

21 March 2017

1 reference

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Proteasomal proteomics: identification of nucleotide-sensitive proteasome-interacting proteins by mass spectrometric analysis of affinity-purified proteasomes

21 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3557657

Synaptic defects in ataxia mice result from a mutation in Usp14, encoding a ubiquitin-specific protease

21 March 2017

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3557657

Molecular architecture of the 26S proteasome holocomplex determined by an integrative approach

21 March 2017

1 reference

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Complete subunit architecture of the proteasome regulatory particle

21 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3557657

Localization of the proteasomal ubiquitin receptors Rpn10 and Rpn13 by electron cryomicroscopy

21 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3557657

Characterization of two polyubiquitin binding sites in the 26 S protease subunit 5a

21 March 2017

1 reference

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Editing of ubiquitin conjugates by an isopeptidase in the 26S proteasome

21 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3557657

Regulators of the proteasome pathway, Uch37 and Rpn13, play distinct roles in mouse development

21 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3557657

Recognition and processing of ubiquitin-protein conjugates by the proteasome

21 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3557657

Enhancement of proteasome activity by a small-molecule inhibitor of USP14

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3557657

Physiological functions of the HECT family of ubiquitin ligases

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3557657

A 26 S protease subunit that binds ubiquitin conjugates

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3557657

Near-atomic resolution structural model of the yeast 26S proteasome.

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3557657

Ubiquitination in signaling to and activation of IKK.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3557657

APC/C-mediated multiple monoubiquitylation provides an alternative degradation signal for cyclin B1

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3557657

Ubiquitin homeostasis is critical for synaptic development and function

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3557657

Inhibition of proteasome deubiquitinating activity as a new cancer therapy

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3557657

Deubiquitinases in cancer: new functions and therapeutic options.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3557657

Cellular strategies for making monoubiquitin signals

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3557657

Defining the geometry of the two-component proteasome degron

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3557657

Regulation of NF-kappaB activity and inducible nitric oxide synthase by regulatory particle non-ATPase subunit 13 (Rpn13).

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3557657

Dependence of phospholipase D1 multi-monoubiquitination on its enzymatic activity and palmitoylation

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3557657

Degradation of some polyubiquitinated proteins requires an intrinsic proteasomal binding element in the substrates

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3557657

The lysine 48 and lysine 63 ubiquitin conjugates are processed differently by the 26 s proteasome

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3557657

The unfoldomics decade: an update on intrinsically disordered proteins.

28 September 2017

1 reference

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Dissection of the carboxyl-terminal domain of the proteasomal subunit Rpn11 in maintenance of mitochondrial structure and function.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3557657

Rpn10-mediated degradation of ubiquitinated proteins is essential for mouse development

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3557657

Certain pairs of ubiquitin-conjugating enzymes (E2s) and ubiquitin-protein ligases (E3s) synthesize nondegradable forked ubiquitin chains containing all possible isopeptide linkages.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3557657

ATP binding and ATP hydrolysis play distinct roles in the function of 26S proteasome

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3557657

Proteasome recruitment and activation of the Uch37 deubiquitinating enzyme by Adrm1.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3557657

Adrm1, a putative cell adhesion regulating protein, is a novel proteasome-associated factor.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3557657

Delivery of ubiquitinated substrates to protein-unfolding machines

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3557657

The deubiquitinating enzyme UCH37 interacts with Smads and regulates TGF-beta signalling

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3557657

Induction of lysosomal membrane permeabilization by compounds that activate p53-independent apoptosis

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3557657

Molecular model of the human 26S proteasome

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3557657

Ubiquitin chain trimming recycles the substrate binding sites of the 26 S proteasome and promotes degradation of lysine 48-linked polyubiquitin conjugates

31 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3557657

ATP binds to proteasomal ATPases in pairs with distinct functional effects, implying an ordered reaction cycle

31 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3557657

ATP-dependent steps in the binding of ubiquitin conjugates to the 26S proteasome that commit to degradation

31 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3557657

Mechanism of substrate unfolding and translocation by the regulatory particle of the proteasome from Methanocaldococcus jannaschii

31 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3557657

The size of the proteasomal substrate determines whether its degradation will be mediated by mono- or polyubiquitylation

31 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3557657

Detection of sequential polyubiquitylation on a millisecond timescale

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3557657

A ubiquitin stress response induces altered proteasome composition.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3557657

Quantitative analysis of in vitro ubiquitinated cyclin B1 reveals complex chain topology

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3557657

A conserved processing mechanism regulates the activity of transcription factors Cubitus interruptus and NF-κB

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3557657

Uch2/Uch37 is the major deubiquitinating enzyme associated with the 26S proteasome in fission yeast.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3557657

An unstructured initiation site is required for efficient proteasome-mediated degradation

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3557657

Proteasomes begin ornithine decarboxylase digestion at the C terminus

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3557657

In vitro assembly and recognition of Lys-63 polyubiquitin chains

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3557657

PA700, an ATP-dependent activator of the 20 S proteasome, is an ATPase containing multiple members of a nucleotide-binding protein family

28 November 2018

1 reference

12 December 2020

Structure of S5a bound to monoubiquitin provides a model for polyubiquitin recognition

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12 December 2020

Functional differences between two major ubiquitin receptors in the proteasome; S5a and hRpn13

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12 December 2020

Modification by single ubiquitin moieties rather than polyubiquitination is sufficient for proteasomal processing of the p105 NF-κB precursor

1 reference

12 December 2020