Hsp70.1 and related lysosomal factors for necrotic neuronal death (Q27012978)

language of work or name

1 reference

February 2012

1 reference

Journal of Neurochemistry

published in

1 reference

volume

120

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issue

4

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page(s)

477-94

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Transacylase and phospholipases in the synthesis of bis(monoacylglycero)phosphate

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Lysosomal biogenesis and function is critical for necrotic cell death in Caenorhabditis elegans

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Oxidatively modified proteins in aging and disease

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Growth arrest and autophagy are required for salivary gland cell degradation in Drosophila

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Mechanistic role of calpains in postischemic neurodegeneration

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Hsp70 protects against UVB induced apoptosis by preventing release of cathepsins and cytochrome c in human melanocytes

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Lysosomal membrane permeabilization in cell death

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Lysosomal membrane permeabilization induces cell death in a mitochondrion-dependent fashion

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Oxidative stress, growth factor starvation and Fas activation may all cause apoptosis through lysosomal leak

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Photo-oxidative disruption of lysosomal membranes causes apoptosis of cultured human fibroblasts

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Lysosomal involvement in apoptosis

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Lipid peroxidation and protein oxidation in Alzheimer's disease brain: potential causes and consequences involving amyloid beta-peptide-associated free radical oxidative stress

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Evidence of oxidative damage in Alzheimer's disease brain: central role for amyloid beta-peptide

21 January 2018

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The effect of mutating arginine-469 on the substrate binding and refolding activities of 70-kDa heat shock cognate protein

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A role for a 70-kilodalton heat shock protein in lysosomal degradation of intracellular proteins

21 January 2018

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Cathepsin-regulated apoptosis

21 January 2018

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Selective disruption of lysosomes in HeLa cells triggers apoptosis mediated by cleavage of Bid by multiple papain-like lysosomal cathepsins

21 January 2018

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Global ischemia activates nuclear factor-kappa B in forebrain neurons of rats.

21 January 2018

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Lysosomes, a meeting point of proteins, chaperones, and proteases

21 January 2018

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The heat shock protein 70 family: Highly homologous proteins with overlapping and distinct functions.

21 January 2018

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NF-kappaB protects neurons from ischemic injury after middle cerebral artery occlusion in mice

21 January 2018

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Oxidized proteins: mechanisms of removal and consequences of accumulation

21 January 2018

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Studies on the mechanisms of autophagy: formation of the autophagic vacuole

21 January 2018

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Studies on the mechanisms of autophagy: maturation of the autophagic vacuole

21 January 2018

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Current insights into the regulation of programmed cell death by NF-kappaB.

21 January 2018

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Proteins as molecular chaperones.

21 January 2018

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New insights on the use of desipramine as an inhibitor for acid ceramidase

21 January 2018

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Chemistry and biochemistry of 4-hydroxynonenal, malonaldehyde and related aldehydes

21 January 2018

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Mitochondrial membrane permeabilization in neuronal injury

21 January 2018

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Regulation of apoptotic and inflammatory cell signaling in cerebral ischemia: the complex roles of heat shock protein 70

21 January 2018

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Necrotic cell death: From reversible mitochondrial uncoupling to irreversible lysosomal permeabilization

21 January 2018

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21 January 2018

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Cell death by necrosis: towards a molecular definition

21 January 2018

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Decreased proteolysis caused by protein aggregates, inclusion bodies, plaques, lipofuscin, ceroid, and 'aggresomes' during oxidative stress, aging, and disease.

21 January 2018

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21 January 2018

Lysosomes in cell death

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Apoptosome-independent activation of the lysosomal cell death pathway by caspase-9.

21 January 2018

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https://api.crossref.org/works/10.1111%2FJ.1471-4159.2011.07596.X

Oxidative stress and neurodegeneration: where are we now?

21 January 2018

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https://api.crossref.org/works/10.1111%2FJ.1471-4159.2011.07596.X

Principles of bioactive lipid signalling: lessons from sphingolipids

21 January 2018

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Biogenesis of multilamellar bodies via autophagy

21 January 2018

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https://api.crossref.org/works/10.1111%2FJ.1471-4159.2011.07596.X

Molecular chaperones in cellular protein folding

21 January 2018

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https://api.crossref.org/works/10.1111%2FJ.1471-4159.2011.07596.X

Shared principles in NF-kappaB signaling

21 January 2018

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https://api.crossref.org/works/10.1111%2FJ.1471-4159.2011.07596.X

A fluorescence-based, high-throughput sphingomyelin assay for the analysis of Niemann-Pick disease and other disorders of sphingomyelin metabolism

21 January 2018

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https://api.crossref.org/works/10.1111%2FJ.1471-4159.2011.07596.X

Ceramide as an activator lipid of cathepsin D.

21 January 2018

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https://api.crossref.org/works/10.1111%2FJ.1471-4159.2011.07596.X

Transacylase formation of bis(monoacylglycerol)phosphate

21 January 2018

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https://api.crossref.org/works/10.1111%2FJ.1471-4159.2011.07596.X

Movement of internalized ligand-receptor complexes along a continuous endosomal reticulum

21 January 2018

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Acid sphingomyelinase deficient mice: a model of types A and B Niemann-Pick disease

21 January 2018

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https://api.crossref.org/works/10.1111%2FJ.1471-4159.2011.07596.X

De novo biosynthesis of the late endosome lipid, bis(monoacylglycero)phosphate

21 January 2018

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https://api.crossref.org/works/10.1111%2FJ.1471-4159.2011.07596.X

Nuclear translocation of NF-kappaB is increased in dopaminergic neurons of patients with parkinson disease

21 January 2018

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https://api.crossref.org/works/10.1111%2FJ.1471-4159.2011.07596.X

Heat shock proteins as cellular lifeguards

21 January 2018

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https://api.crossref.org/works/10.1111%2FJ.1471-4159.2011.07596.X

Tumor suppression by autophagy through the management of metabolic stress

21 January 2018

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https://api.crossref.org/works/10.1111%2FJ.1471-4159.2011.07596.X

Regulation of apoptosis-associated lysosomal membrane permeabilization

21 January 2018

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https://api.crossref.org/works/10.1111%2FJ.1471-4159.2011.07596.X

Metals, oxidative stress and neurodegenerative disorders

21 January 2018

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https://api.crossref.org/works/10.1111%2FJ.1471-4159.2011.07596.X

Sphingosine-induced apoptosis is dependent on lysosomal proteases

21 January 2018

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https://api.crossref.org/works/10.1111%2FJ.1471-4159.2011.07596.X

The preservation of ultrastructure in saturated phosphatidyl cholines by tannic acid in model systems and type II pneumocytes

21 January 2018

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The probable role of phosphatidyl cholines in the tannic acid enhancement of cytomembrane electron contrast

21 January 2018

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Transcription factor NF-kappaB is activated in primary neurons by amyloid beta peptides and in neurons surrounding early plaques from patients with Alzheimer disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2011.07596.X

Apoptosis: A Basic Biological Phenomenon with Wideranging Implications in Tissue Kinetics

21 January 2018

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https://api.crossref.org/works/10.1111%2FJ.1471-4159.2011.07596.X

Lysosomal involvement in cell death and cancer.

21 January 2018

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https://api.crossref.org/works/10.1111%2FJ.1471-4159.2011.07596.X

Hsp70 stabilizes lysosomes and reverts Niemann-Pick disease-associated lysosomal pathology.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2011.07596.X

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2011.07596.X

Principles of lysosomal membrane digestion: stimulation of sphingolipid degradation by sphingolipid activator proteins and anionic lysosomal lipids

21 January 2018

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https://api.crossref.org/works/10.1111%2FJ.1471-4159.2011.07596.X

Lysosomal degradation of membrane lipids

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2011.07596.X

Interactions of acid sphingomyelinase and lipid bilayers in the presence of the tricyclic antidepressant desipramine

21 January 2018

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https://api.crossref.org/works/10.1111%2FJ.1471-4159.2011.07596.X

Impairment of starvation-induced and constitutive autophagy in Atg7-deficient mice

21 January 2018

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https://api.crossref.org/works/10.1111%2FJ.1471-4159.2011.07596.X

Synaptic currents in cerebellar Purkinje cells

21 January 2018

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https://api.crossref.org/works/10.1111%2FJ.1471-4159.2011.07596.X

Stat3 controls lysosomal-mediated cell death in vivo.

21 January 2018

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https://api.crossref.org/works/10.1111%2FJ.1471-4159.2011.07596.X

Autophagic cell death: the story of a misnomer

21 January 2018

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https://api.crossref.org/works/10.1111%2FJ.1471-4159.2011.07596.X

The lipid composition of autophagic vacuoles regulates expression of multilamellar bodies

21 January 2018

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https://api.crossref.org/works/10.1111%2FJ.1471-4159.2011.07596.X

Effects of hsp70.1 gene knockout on the mitochondrial apoptotic pathway after focal cerebral ischemia.

21 January 2018

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https://api.crossref.org/works/10.1111%2FJ.1471-4159.2011.07596.X

Developmental apoptosis in C. elegans: a complex CEDnario

21 January 2018

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https://api.crossref.org/works/10.1111%2FJ.1471-4159.2011.07596.X

Carbonyl modified proteins in cellular regulation, aging, and disease

21 January 2018

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Cholesterol accumulation is associated with lysosomal dysfunction and autophagic stress in Npc1 -/- mouse brain

21 January 2018

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Stimulation of acid sphingomyelinase activity by lysosomal lipids and sphingolipid activator proteins

21 January 2018

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Interfacial regulation of acid ceramidase activity. Stimulation of ceramide degradation by lysosomal lipids and sphingolipid activator proteins

21 January 2018

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https://api.crossref.org/works/10.1111%2FJ.1471-4159.2011.07596.X

Elevated 4-hydroxynonenal in ventricular fluid in Alzheimer's disease.

21 January 2018

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https://api.crossref.org/works/10.1111%2FJ.1471-4159.2011.07596.X

Necrotic cell death: harnessing the Dark side of the Force in mammary gland involution

21 January 2018

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https://api.crossref.org/works/10.1111%2FJ.1471-4159.2011.07596.X

An intracellular serpin regulates necrosis by inhibiting the induction and sequelae of lysosomal injury

21 January 2018

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https://api.crossref.org/works/10.1111%2FJ.1471-4159.2011.07596.X

Neuropathology of the acid sphingomyelinase knockout mouse model of Niemann-Pick A disease including structure-function studies associated with cerebellar Purkinje cell degeneration.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2011.07596.X

Self-eating and self-killing: crosstalk between autophagy and apoptosis

21 January 2018

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https://api.crossref.org/works/10.1111%2FJ.1471-4159.2011.07596.X

Oxyradicals and DNA damage

21 January 2018

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https://api.crossref.org/works/10.1111%2FJ.1471-4159.2011.07596.X

Hsp70 overexpression sequesters AIF and reduces neonatal hypoxic/ischemic brain injury.

21 January 2018

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https://api.crossref.org/works/10.1111%2FJ.1471-4159.2011.07596.X

Stratum corneum lipid abnormalities in UVB-irradiated skin.

21 January 2018

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Molecular chaperones and the stress of oncogenesis.

21 January 2018

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Nuclear factor-kappaB contributes to infarction after permanent focal ischemia

21 January 2018

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Selective depletion of heat shock protein 70 (Hsp70) activates a tumor-specific death program that is independent of caspases and bypasses Bcl-2.

21 January 2018

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https://api.crossref.org/works/10.1111%2FJ.1471-4159.2011.07596.X

Heat shock protein 70 promotes cell survival by inhibiting lysosomal membrane permeabilization

21 January 2018

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https://api.crossref.org/works/10.1111%2FJ.1471-4159.2011.07596.X

Role of oxidative carbonylation in protein quality control and senescence

21 January 2018

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https://api.crossref.org/works/10.1111%2FJ.1471-4159.2011.07596.X

Proteomic identification of carbonylated proteins in the monkey hippocampus after ischemia-reperfusion

21 January 2018

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https://api.crossref.org/works/10.1111%2FJ.1471-4159.2011.07596.X

Cellular injury induced by oxidative stress is mediated through lysosomal damage.

21 January 2018

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https://api.crossref.org/works/10.1111%2FJ.1471-4159.2011.07596.X

Acid sphingomyelinase-deficient mice mimic the neurovisceral form of human lysosomal storage disease (Niemann-Pick disease).

21 January 2018

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https://api.crossref.org/works/10.1111%2FJ.1471-4159.2011.07596.X

HSP70 and lysosomal storage disorders: novel therapeutic opportunities

21 January 2018

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https://api.crossref.org/works/10.1111%2FJ.1471-4159.2011.07596.X

Post-ischemic brain damage: NF-kappaB dimer heterogeneity as a molecular determinant of neuron vulnerability.

21 January 2018

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https://api.crossref.org/works/10.1111%2FJ.1471-4159.2011.07596.X

Delivery of endocytosed membrane proteins to the lysosome

21 January 2018

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https://api.crossref.org/works/10.1111%2FJ.1471-4159.2011.07596.X

Ischemic neuronal death in the rat hippocampus: the calpain-calpastatin-caspase hypothesis

21 January 2018

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https://api.crossref.org/works/10.1111%2FJ.1471-4159.2011.07596.X

Heat-shock protein 70 antagonizes apoptosis-inducing factor

21 January 2018

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https://api.crossref.org/works/10.1111%2FJ.1471-4159.2011.07596.X

Lysosomal-mitochondrial cross-talk during cell death

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2011.07596.X

NF-kappaB signaling in cerebral ischemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2011.07596.X

A new puffing pattern induced by temperature shock and DNP in drosophila

21 January 2018

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https://api.crossref.org/works/10.1111%2FJ.1471-4159.2011.07596.X

Members of the heat-shock protein 70 family promote cancer cell growth by distinct mechanisms

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2011.07596.X

Calpain-mediated Hsp70.1 cleavage in hippocampal CA1 neuronal death

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2011.07596.X

NF-kappaB dimers in the regulation of neuronal survival.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2011.07596.X

Sphingomyelinase deficiency (Niemann-Pick disease) in a Hereford calf

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2011.07596.X

Principles of lysosomal membrane degradation: Cellular topology and biochemistry of lysosomal lipid degradation

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2011.07596.X

Inhibition of receptor internalization by monodansylcadaverine selectively blocks p55 tumor necrosis factor receptor death domain signaling

21 January 2018

1 reference

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3-Methyladenine: specific inhibitor of autophagic/lysosomal protein degradation in isolated rat hepatocytes

21 January 2018

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https://api.crossref.org/works/10.1111%2FJ.1471-4159.2011.07596.X

The unexpected role of acid sphingomyelinase in cell death and the pathophysiology of common diseases

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2011.07596.X

Presence of 4-hydroxynonenal in cerebrospinal fluid of patients with sporadic amyotrophic lateral sclerosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2011.07596.X

Oxidative stress in Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2011.07596.X

Cardiolipin and its metabolites move from mitochondria to other cellular membranes during death receptor-mediated apoptosis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2011.07596.X

Reactive oxygen-mediated protein oxidation in aging and disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2011.07596.X

Reactive oxygen-mediated protein oxidation in aging and disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2011.07596.X

Lysosomal cysteine cathepsins: signaling pathways in apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2011.07596.X

Redox proteomic analysis of carbonylated brain proteins in mild cognitive impairment and early Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2011.07596.X

Specific aspartyl and calpain proteases are required for neurodegeneration in C. elegans

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2011.07596.X

The vacuolar H+ -ATPase mediates intracellular acidification required for neurodegeneration in C. elegans

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2011.07596.X

Calpain-mediated degradation of p35 to p25 in postmortem human and rat brains.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2011.07596.X

21 January 2018

Lysosomal labilization

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2011.07596.X

Protein synthesis in salivary glands of Drosophila melanogaster: relation to chromosome puffs

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2011.07596.X

Proteomic approaches to oxidative protein modifications implicated in the mechanism of aging

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2011.07596.X

Lysosomes as "suicide bags" in cell death: myth or reality?

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2011.07596.X

Molecular mechanisms of necroptosis: an ordered cellular explosion

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2011.07596.X

Lysosomal storage disorders

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2011.07596.X

Implication of cysteine proteases calpain, cathepsin and caspase in ischemic neuronal death of primates

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2011.07596.X

Ca2+-dependent proteases in ischemic neuronal death: a conserved 'calpain-cathepsin cascade' from nematodes to primates

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2011.07596.X

The role of lysosomal rupture in neuronal death

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2011.07596.X

Transient brain ischaemia provokes Ca2+, PIP2 and calpain responses prior to delayed neuronal death in monkeys.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2011.07596.X

Inhibition of ischaemic hippocampal neuronal death in primates with cathepsin B inhibitor CA-074: a novel strategy for neuroprotection based on 'calpain-cathepsin hypothesis'.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2011.07596.X

Sustained calpain activation associated with lysosomal rupture executes necrosis of the postischemic CA1 neurons in primates

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2011.07596.X

Why are hippocampal CA1 neurons vulnerable but motor cortex neurons resistant to transient ischemia?

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2011.07596.X

Necrotic death as a cell fate

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2011.07596.X

Stability in times of stress

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2011.07596.X