Dynamic modelling of pathways to cellular senescence reveals strategies for targeted interventions (Q27321555)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25166345%20AND%20SRC:MED&resulttype=core&format=json

31 May 2020

Glyn Nelson

2

1 reference

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31 May 2020

Elsje G Otten

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25166345%20AND%20SRC:MED&resulttype=core&format=json

31 May 2020

Viktor Korolchuk

4

1 reference

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31 May 2020

Thomas von Zglinicki

6

1 reference

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31 May 2020

Daryl P Shanley

7

1 reference

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31 May 2020

author name string

Thomas B L Kirkwood

5

1 reference

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PLOS Computational Biology

31 May 2020

language of work or name

English

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publication date

August 2014

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published in

1 reference

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31 May 2020

volume

10

1 reference

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31 May 2020

issue

8

1 reference

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31 May 2020

page(s)

e1003728

1 reference

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Creative Commons Attribution 4.0 International

31 May 2020

copyright license

start time

28 August 2014

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

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describes a project that uses

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC4159174/fullTextXML

based on heuristic

inferred from PubMed Central ID database lookup

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Resveratrol improves mitochondrial function and protects against metabolic disease by activating SIRT1 and PGC-1alpha

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Prolonged rapamycin treatment inhibits mTORC2 assembly and Akt/PKB

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Nutrient control of glucose homeostasis through a complex of PGC-1alpha and SIRT1

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28 September 2017

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28 September 2017

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28 September 2017

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28 September 2017

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p38MAPK is a novel DNA damage response-independent regulator of the senescence-associated secretory phenotype

28 September 2017

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28 September 2017

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28 September 2017

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The association of AMPK with ULK1 regulates autophagy

28 September 2017

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28 September 2017

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FoxO transcription factors promote autophagy in cardiomyocytes

28 September 2017

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28 September 2017

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28 September 2017

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28 September 2017

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Living on a break: cellular senescence as a DNA-damage response

28 September 2017

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Redox control of cell fate by MAP kinase: physiological roles of ASK1-MAP kinase pathway in stress signaling

28 September 2017

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28 September 2017

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Data-based identifiability analysis of non-linear dynamical models

28 September 2017

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Mitochondrial dysfunction accounts for the stochastic heterogeneity in telomere-dependent senescence

28 September 2017

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Senescent human fibroblasts increase the early growth of xenograft tumors via matrix metalloproteinase secretion

28 September 2017

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28 September 2017

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Senescent fibroblasts promote epithelial cell growth and tumorigenesis: a link between cancer and aging

28 September 2017

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Lipofuscin accumulation in proliferating fibroblasts in vitro: an indicator of oxidative stress.

28 September 2017

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Molecular analysis of H2O2-induced senescent-like growth arrest in normal human fibroblasts: p53 and Rb control G1 arrest but not cell replication

28 September 2017

1 reference

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Adult-onset, short-term dietary restriction reduces cell senescence in mice.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4159174

Dynamical modeling and multi-experiment fitting with PottersWheel

31 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4159174

Modulation of glutamine metabolism by the PI(3)K-PKB-FOXO network regulates autophagy.

31 May 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PCBI.1003728

DAF-16 target genes that control C. elegans life-span and metabolism.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PCBI.1003728

A modelling-experimental approach reveals insulin receptor substrate (IRS)-dependent regulation of adenosine monosphosphate-dependent kinase (AMPK) by insulin

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PCBI.1003728

Inappropriate activation of the TSC/Rheb/mTOR/S6K cassette induces IRS1/2 depletion, insulin resistance, and cell survival deficiencies

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PCBI.1003728

Discovery of 9-(6-aminopyridin-3-yl)-1-(3-(trifluoromethyl)phenyl)benzo[h][1,6]naphthyridin-2(1H)-one (Torin2) as a potent, selective, and orally available mammalian target of rapamycin (mTOR) inhibitor for treatment of cancer.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PCBI.1003728

Principles of the mitochondrial fusion and fission cycle in neurons

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PCBI.1003728

Monitoring mitochondrial dynamics and complex I dysfunction in neurons: implications for Parkinson's disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PCBI.1003728

Synthetic lethal metabolic targeting of cellular senescence in cancer therapy.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PCBI.1003728

DNA damage response and cellular senescence in tissues of aging mice

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/25166345

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1371/JOURNAL.PCBI.1003728

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25166345%20AND%20SRC:MED&resulttype=core&format=json

journals/ploscb/PezzeNOKKZS14

31 May 2020

DBLP publication ID

1 reference

DBLP Dataset 2021-01-02

28 January 2021

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25166345%20AND%20SRC:MED&resulttype=core&format=json

31 May 2020

PubMed publication ID

25166345

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25166345%20AND%20SRC:MED&resulttype=core&format=json