Cell cycle regulation of DNA double-strand break end resection by Cdk1-dependent Dna2 phosphorylation (Q27937625)

PubMed

21841787

1 December 2016

title

Cell cycle regulation of DNA double-strand break end resection by Cdk1-dependent Dna2 phosphorylation (English)

1 reference

PubMed

Cyclin-dependent serine/threonine-protein kinase CDC28 YBR160W

1 December 2016

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1 reference

Protein kinase MEC1 YBR136W

1 reference

Bifunctional ATP-dependent DNA helicase/ssDNA endodeoxyribonuclease DNA2 YHR164C

1 reference

Rad2 family nuclease EXO1 YOR033C

1 reference

1 reference

Xuefeng Chen

1

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Hengyao Niu

2

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Woo-Hyun Chung

3

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Zhu Zhu

4

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Alma Papusha

5

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Eun Yong Shim

6

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Sang Eun Lee

7

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Patrick Sung

8

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Grzegorz Ira

Nature Structural & Molecular Biology

9

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language of work or name

English

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publication date

14 August 2011

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published in

1 reference

PubMed

21841787

describes a project that uses

1 December 2016

volume

18

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issue

9

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page(s)

1015-9

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ImageQuant

1 reference

Europe PubMed Central

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC3168961/fullTextXML

based on heuristic

inferred from PubMed Central ID database lookup

cites work

BLM-DNA2-RPA-MRN and EXO1-BLM-RPA-MRN constitute two DNA end resection machineries for human DNA break repair

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An overview of Cdk1-controlled targets and processes

20 March 2017

1 reference

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Cdk1 targets Srs2 to complete synthesis-dependent strand annealing and to promote recombinational repair

20 March 2017

1 reference

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Multiple pathways regulate 3' overhang generation at S. cerevisiae telomeres.

20 March 2017

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Systematic identification of cell cycle-dependent yeast nucleocytoplasmic shuttling proteins by prediction of composite motifs

20 March 2017

1 reference

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Cell cycle, CDKs and cancer: a changing paradigm

20 March 2017

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Sae2, Exo1 and Sgs1 collaborate in DNA double-strand break processing

20 March 2017

1 reference

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CDK targets Sae2 to control DNA-end resection and homologous recombination

20 March 2017

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A network of multi-tasking proteins at the DNA replication fork preserves genome stability

20 March 2017

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CDK-dependent phosphorylation of BRCA2 as a regulatory mechanism for recombinational repair

20 March 2017

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DNA end resection, homologous recombination and DNA damage checkpoint activation require CDK1

20 March 2017

1 reference

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In vivo roles of Rad52, Rad54, and Rad55 proteins in Rad51-mediated recombination.

20 March 2017

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20 March 2017

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Human CtIP mediates cell cycle control of DNA end resection and double strand break repair

20 March 2017

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Temporally and biochemically distinct activities of Exo1 during meiosis: double-strand break resection and resolution of double Holliday junctions

20 March 2017

1 reference

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Sgs1 helicase and two nucleases Dna2 and Exo1 resect DNA double-strand break ends

20 March 2017

1 reference

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ATM- and cell cycle-dependent regulation of ATR in response to DNA double-strand breaks

7 April 2017

1 reference

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Srs2 and Sgs1-Top3 suppress crossovers during double-strand break repair in yeast

7 April 2017

1 reference

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Targets of the cyclin-dependent kinase Cdk1

7 April 2017

1 reference

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A chemical switch for inhibitor-sensitive alleles of any protein kinase

7 April 2017

1 reference

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DNA end resection by Dna2–Sgs1–RPA and its stimulation by Top3–Rmi1 and Mre11–Rad50–Xrs2

7 April 2017

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Mechanism of the ATP-dependent DNA end-resection machinery from Saccharomyces cerevisiae.

29 September 2017

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Ku prevents Exo1 and Sgs1-dependent resection of DNA ends in the absence of a functional MRX complex or Sae2

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3168961

Dynamics of Rad9 chromatin binding and checkpoint function are mediated by its dimerization and are cell cycle-regulated by CDK1 activity

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3168961

A truncated DNA-damage-signaling response is activated after DSB formation in the G1 phase of Saccharomyces cerevisiae

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3168961

CtIP-BRCA1 modulates the choice of DNA double-strand-break repair pathway throughout the cell cycle.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3168961

Break dosage, cell cycle stage and DNA replication influence DNA double strand break response

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3168961

Differential regulation of the cellular response to DNA double-strand breaks in G1.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3168961

Ctp1 is a cell-cycle-regulated protein that functions with Mre11 complex to control double-strand break repair by homologous recombination

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3168961

Evidence suggesting that Pif1 helicase functions in DNA replication with the Dna2 helicase/nuclease and DNA polymerase delta

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3168961

The CDK regulates repair of double-strand breaks by homologous recombination during the cell cycle

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3168961

Two modes of DNA double-strand break repair are reciprocally regulated through the fission yeast cell cycle

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3168961

Cdc2-cyclin B kinase activity links Crb2 and Rqh1-topoisomerase III

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3168961

Mre11 and Exo1 contribute to the initiation and processivity of resection at meiotic double-strand breaks made independently of Spo11.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3168961

Mre11-Rad50-Xrs2 and Sae2 promote 5' strand resection of DNA double-strand breaks

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3168961

Saccharomyces cerevisiae Mre11/Rad50/Xrs2 and Ku proteins regulate association of Exo1 and Dna2 with DNA breaks

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3168961

Saccharomyces CDK1 phosphorylates Rad53 kinase in metaphase, influencing cellular morphogenesis

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3168961

DNA helicases Sgs1 and BLM promote DNA double-strand break resection

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3168961

The Yku70-Yku80 complex contributes to regulate double-strand break processing and checkpoint activation during the cell cycle

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3168961

Cell-cycle-regulated phosphorylation of DNA replication factor A from human and yeast cells

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3168961

Cell cycle-dependent phosphorylation of Rad53 kinase by Cdc5 and Cdc28 modulates checkpoint adaptation.

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3168961

Separable roles for Exonuclease I in meiotic DNA double-strand break repair.

2 June 2018

1 reference

Exo1 competes with repair synthesis, converts NER intermediates to long ssDNA gaps, and promotes checkpoint activation.

21 January 2018

1 reference

Exo1 processes stalled replication forks and counteracts fork reversal in checkpoint-defective cells

21 January 2018

1 reference

Cyclin specificity in the phosphorylation of cyclin-dependent kinase substrates.

21 January 2018

1 reference

Role of Dnl4-Lif1 in nonhomologous end-joining repair complex assembly and suppression of homologous recombination

21 January 2018

1 reference

31 March 2020

Identifiers

DOI

10.1038/NSMB.2105

1 reference

Dimensions Publication ID

1013853290

0 references

1 reference

1 reference

21841787

1 reference