Influence of CRACC, a SLAM family receptor coupled to the adaptor EAT-2, on natural killer cell function (Q28115588)

Signaling lymphocytic activation molecule family member 1

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SH2 domain-containing protein 1B

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SLAM family member 7

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SH2 domain containing 1A

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5

André Veillette

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3 January 2017

Mario-Ernesto Cruz-Munoz

1

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3 January 2017

Zhongjun Dong

2

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3 January 2017

Xiaochu Shi

3

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3 January 2017

Shaohua Zhang

The SAP and SLAM families in immune responses and X-linked lymphoproliferative disease

4

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3 January 2017

language of work or name

English

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publication date

1 March 2009

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3 January 2017

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3 January 2017

10

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3 January 2017

3

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3 January 2017

297–305

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3 January 2017

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NTB-A [correction of GNTB-A], a novel SH2D1A-associated surface molecule contributing to the inability of natural killer cells to kill Epstein-Barr virus-infected B cells in X-linked lymphoproliferative disease

21 April 2017

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Association of the X-linked lymphoproliferative disease gene product SAP/SH2D1A with 2B4, a natural killer cell-activating molecule, is dependent on phosphoinositide 3-kinase

21 April 2017

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CS1, a novel member of the CD2 family, is homophilic and regulates NK cell function

21 April 2017

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Homotypic interactions mediated by Slamf1 and Slamf6 receptors control NKT cell lineage development

21 April 2017

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Requirement of homotypic NK-cell interactions through 2B4(CD244)/CD48 in the generation of NK effector functions

21 April 2017

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Negative regulation of natural killer cell function by EAT-2, a SAP-related adaptor

21 April 2017

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Regulation of SLAM-mediated signal transduction by SAP, the X-linked lymphoproliferative gene product

21 April 2017

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SAP couples Fyn to SLAM immune receptors

21 April 2017

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The X-linked lymphoproliferative-disease gene product SAP regulates signals induced through the co-receptor SLAM

21 April 2017

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Dual functional roles for the X-linked lymphoproliferative syndrome gene product SAP/SH2D1A in signaling through the signaling lymphocyte activation molecule (SLAM) family of immune receptors

21 April 2017

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Early expression of triggering receptors and regulatory role of 2B4 in human natural killer cell precursors undergoing in vitro differentiation

21 April 2017

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X-linked lymphoproliferative disease. 2B4 molecules displaying inhibitory rather than activating function are responsible for the inability of natural killer cells to kill Epstein-Barr virus-infected cells

21 April 2017

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21 April 2017

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Natural killer cell signaling pathways

21 April 2017

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Roles of the NKG2D immunoreceptor and its ligands

21 January 2018

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Regulation of cellular and humoral immune responses by the SLAM and SAP families of molecules.

21 January 2018

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Consequence of the SLAM-SAP signaling pathway in innate-like and conventional lymphocytes

21 January 2018

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NK cell regulation by SLAM family receptors and SAP-related adapters

21 January 2018

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Control of T lymphocyte signaling by Ly108, a signaling lymphocytic activation molecule family receptor implicated in autoimmunity

21 January 2018

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Functional requirement for SAP in 2B4-mediated activation of human natural killer cells as revealed by the X-linked lymphoproliferative syndrome

21 January 2018

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Patients with X-linked lymphoproliferative disease have a defect in 2B4 receptor-mediated NK cell cytotoxicity

21 January 2018

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Regulation of natural cytotoxicity by the adaptor SAP and the Src-related kinase Fyn.

21 January 2018

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2B4 acts as a non-major histocompatibility complex binding inhibitory receptor on mouse natural killer cells

21 January 2018

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Activation of NK cell-mediated cytotoxicity by a SAP-independent receptor of the CD2 family

21 January 2018

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CS1, a potential new therapeutic antibody target for the treatment of multiple myeloma

21 January 2018

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Anti-CS1 humanized monoclonal antibody HuLuc63 inhibits myeloma cell adhesion and induces antibody-dependent cellular cytotoxicity in the bone marrow milieu

21 January 2018

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2B4 (CD244), NTB-A and CRACC (CS1) stimulate cytotoxicity but no proliferation in human NK cells

21 January 2018

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2B4 (CD244) and CS1: novel members of the CD2 subset of the immunoglobulin superfamily molecules expressed on natural killer cells and other leukocytes

21 January 2018

2 references

21 January 2018

12 December 2020

Rae1 and H60 ligands of the NKG2D receptor stimulate tumour immunity

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SLAM family receptors and SAP-related adaptors: matters arising

21 January 2018

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The SLAM-associated protein signaling pathway is required for development of CD4+ T cells selected by homotypic thymocyte interaction

21 January 2018

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Binding of SAP SH2 domain to FynT SH3 domain reveals a novel mechanism of receptor signalling in immune regulation

21 January 2018

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Mouse novel Ly9: a new member of the expanding CD150 (SLAM) family of leukocyte cell-surface receptors

21 January 2018

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The dual-function CD150 receptor subfamily: the viral attraction

21 January 2018

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Targeted disruption of the 2B4 gene in mice reveals an in vivo role of 2B4 (CD244) in the rejection of B16 melanoma cells.

21 January 2018

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21 January 2018

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SAP expression in T cells, not in B cells, is required for humoral immunity

21 January 2018

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Selective development of CD4+ T cells in transgenic mice expressing a class II MHC-restricted antigen receptor

21 January 2018

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In vivo effects of anti-asialo GM1. I. Reduction of NK activity and enhancement of transplanted tumor growth in nude mice

21 January 2018

1 reference

PubMed

12 December 2020

Cloning and characterization of the 2B4 gene encoding a molecule associated with non-MHC-restricted killing mediated by activated natural killer cells and T cells

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PubMed

12 December 2020

The cytotoxicity receptor CRACC (CS-1) recruits EAT-2 and activates the PI3K and phospholipase Cgamma signaling pathways in human NK cells

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PubMed

12 December 2020