Molecular pathogenesis of acute promyelocytic leukaemia and APL variants (Q28203259)

Best Practice and Research: Clinical Haematology

Europe PubMed Central

title

Molecular pathogenesis of acute promyelocytic leukaemia and APL variants (English)

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Jonathan D Licht

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author name string

Andres Sirulnik

series ordinal

1

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Ari Melnick

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2

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Arthur Zelent

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3

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language of work or name

English

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publication date

September 2003

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published in

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volume

16

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issue

3

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page(s)

387-408

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cites work

Advances in the understanding and management of acute promyelocytic leukemia

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7 January 2021

15/17 translocation, a consistent chromosomal change in acute promyelocytic leukaemia

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7 January 2021

The t(15;17) translocation of acute promyelocytic leukaemia fuses the retinoic acid receptor alpha gene to a novel transcribed locus

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7 January 2021

Chromosomal translocation t(15;17) in human acute promyelocytic leukemia fuses RARα with a novel putative transcription factor, PML

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7 January 2021

The nuclear receptor superfamily: the second decade

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7 January 2021

Characterization of three RXR genes that mediate the action of 9-cis retinoic acid

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7 January 2021

Crystal structure of the RAR-gamma ligand-binding domain bound to all-trans retinoic acid

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7 January 2021

Crystal structure of the ligand-binding domain of the human nuclear receptor RXR-alpha

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7 January 2021

The role of retinoids and retinoic acid receptors in normal hematopoiesis

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7 January 2021

Neutrophil maturation and the role of retinoic acid

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7 January 2021

Function of RARalpha during the maturation of neutrophils

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7 January 2021

Positive and negative regulation of granulopoiesis by endogenous RARalpha

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7 January 2021

A dominant negative retinoic acid receptor blocks neutrophil differentiation at the promyelocyte stage

1 reference

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7 January 2021

Normal development and growth of mice carrying a targeted disruption of the alpha 1 retinoic acid receptor gene

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7 January 2021

Function of retinoic acid receptor gamma in the mouse

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7 January 2021

Translocation breakpoint of acute promyelocytic leukemia lies within the retinoic acid receptor alpha locus

1 reference

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7 January 2021

Fusion of retinoic acid receptor alpha to NuMA, the nuclear mitotic apparatus protein, by a variant translocation in acute promyelocytic leukaemia

1 reference

https://api.crossref.org/works/10.1016%2FS1521-6926%2803%2900062-8

7 January 2021

The signal transducer and activator of transcription STAT5b gene is a new partner of retinoic acid receptor alpha in acute promyelocytic-like leukaemia

1 reference

https://api.crossref.org/works/10.1016%2FS1521-6926%2803%2900062-8

7 January 2021

Amino-terminal protein-protein interaction motif (POZ-domain) is responsible for activities of the promyelocytic leukemia zinc finger-retinoic acid receptor-alpha fusion protein

1 reference

https://api.crossref.org/works/10.1016%2FS1521-6926%2803%2900062-8

7 January 2021

PMLRAR homodimers: distinct DNA binding properties and heteromeric interactions with RXR

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https://api.crossref.org/works/10.1016%2FS1521-6926%2803%2900062-8

7 January 2021

Acquisition of oncogenic potential by RAR chimeras in acute promyelocytic leukemia through formation of homodimers.

1 reference

https://api.crossref.org/works/10.1016%2FS1521-6926%2803%2900062-8

7 January 2021

Oligomerization of RAR and AML1 transcription factors as a novel mechanism of oncogenic activation.

1 reference

https://api.crossref.org/works/10.1016%2FS1521-6926%2803%2900062-8

7 January 2021

A bcr-3 isoform of RARalpha-PML potentiates the development of PML-RARalpha-driven acute promyelocytic leukemia

1 reference

https://api.crossref.org/works/10.1016%2FS1521-6926%2803%2900062-8

7 January 2021

Two critical hits for promyelocytic leukemia

1 reference

https://api.crossref.org/works/10.1016%2FS1521-6926%2803%2900062-8

7 January 2021

In vitro response to all-trans retinoic acid of acute promyelocytic leukemias with nonreciprocal PML/RARA or RARA/PML fusion genes.

1 reference

https://api.crossref.org/works/10.1016%2FS1521-6926%2803%2900062-8

7 January 2021

Reciprocal products of chromosomal translocations in human cancer pathogenesis: key players or innocent bystanders?

1 reference

https://api.crossref.org/works/10.1016%2FS1521-6926%2803%2900062-8

7 January 2021

Translocations of the RARalpha gene in acute promyelocytic leukemia

1 reference

https://api.crossref.org/works/10.1016%2FS1521-6926%2803%2900062-8

7 January 2021

Finding a role for PML in APL pathogenesis: a critical assessment of potential PML activities

1 reference

https://api.crossref.org/works/10.1016%2FS1521-6926%2803%2900062-8

7 January 2021

The role of PML in tumor suppression

1 reference

https://api.crossref.org/works/10.1016%2FS1521-6926%2803%2900062-8

7 January 2021

The function of PML in p53-dependent apoptosis

1 reference

https://api.crossref.org/works/10.1016%2FS1521-6926%2803%2900062-8

7 January 2021

Deconstructing PML-induced premature senescence

1 reference

https://api.crossref.org/works/10.1016%2FS1521-6926%2803%2900062-8

7 January 2021

Atmospheric carbon dioxide concentrations over the past 60 million years

1 reference

https://api.crossref.org/works/10.1016%2FS1521-6926%2803%2900062-8

7 January 2021

DNA damage-induced translocation of the Werner helicase is regulated by acetylation

1 reference

https://api.crossref.org/works/10.1016%2FS1521-6926%2803%2900062-8

7 January 2021

Functional interaction of p53 and BLM DNA helicase in apoptosis

1 reference

https://api.crossref.org/works/10.1016%2FS1521-6926%2803%2900062-8

7 January 2021

UV-C-induced DNA damage leads to p53-dependent nuclear trafficking of PML.

1 reference

https://api.crossref.org/works/10.1016%2FS1521-6926%2803%2900062-8

7 January 2021

Role of PML in cell growth and the retinoic acid pathway

1 reference

https://api.crossref.org/works/10.1016%2FS1521-6926%2803%2900062-8

7 January 2021

The proline-rich homeodomain protein, PRH, is a tissue-specific inhibitor of eIF4E-dependent cyclin D1 mRNA transport and growth

1 reference

https://api.crossref.org/works/10.1016%2FS1521-6926%2803%2900062-8

7 January 2021

PML RING suppresses oncogenic transformation by reducing the affinity of eIF4E for mRNA.

1 reference

https://api.crossref.org/works/10.1016%2FS1521-6926%2803%2900062-8

7 January 2021

The promyelocytic leukemia (PML) protein suppresses cyclin D1 protein production by altering the nuclear cytoplasmic distribution of cyclin D1 mRNA.

1 reference

https://api.crossref.org/works/10.1016%2FS1521-6926%2803%2900062-8

7 January 2021

Transcriptional repression by the promyelocytic leukemia protein, PML.

1 reference

https://api.crossref.org/works/10.1016%2FS1521-6926%2803%2900062-8

7 January 2021

Modulation of Fos-mediated AP-1 transcription by the promyelocytic leukemia protein.

1 reference

https://api.crossref.org/works/10.1016%2FS1521-6926%2803%2900062-8

7 January 2021

Role of PML and PML-RARalpha in Mad-mediated transcriptional repression

1 reference

https://api.crossref.org/works/10.1016%2FS1521-6926%2803%2900062-8

7 January 2021

The growth suppressor PML represses transcription by functionally and physically interacting with histone deacetylases

1 reference

https://api.crossref.org/works/10.1016%2FS1521-6926%2803%2900062-8

7 January 2021

Modulation of CREB binding protein function by the promyelocytic (PML) oncoprotein suggests a role for nuclear bodies in hormone signaling

1 reference

https://api.crossref.org/works/10.1016%2FS1521-6926%2803%2900062-8

7 January 2021

Localization of nascent RNA and CREB binding protein with the PML-containing nuclear body.

1 reference

https://api.crossref.org/works/10.1016%2FS1521-6926%2803%2900062-8

7 January 2021

Secondary cytogenetic changes in acute promyelocytic leukemia--prognostic importance in patients treated with chemotherapy alone and association with the intron 3 breakpoint of the PML gene: a Cancer and Leukemia Group B study

1 reference

https://api.crossref.org/works/10.1016%2FS1521-6926%2803%2900062-8

7 January 2021

Acute promyelocytic leukemia: a model for the role of molecular diagnosis and residual disease monitoring in directing treatment approach in acute myeloid leukemia

1 reference

https://api.crossref.org/works/10.1016%2FS1521-6926%2803%2900062-8

7 January 2021

Methyltransferase recruitment and DNA hypermethylation of target promoters by an oncogenic transcription factor

1 reference

https://api.crossref.org/works/10.1016%2FS1521-6926%2803%2900062-8

7 January 2021

CCAAT/enhancer binding protein epsilon is a potential retinoid target gene in acute promyelocytic leukemia treatment

1 reference

https://api.crossref.org/works/10.1016%2FS1521-6926%2803%2900062-8

7 January 2021

CCAAT/Enhancer binding proteins repress the leukemic phenotype of acute myeloid leukemia

1 reference

https://api.crossref.org/works/10.1016%2FS1521-6926%2803%2900062-8

7 January 2021

Diagnosis of acute promyelocytic leukaemia by RT-PCR: detection of PML-RARA and RARA-PML fusion transcripts

1 reference

https://api.crossref.org/works/10.1016%2FS1521-6926%2803%2900062-8

7 January 2021

Expression pattern of the RAR alpha-PML fusion gene in acute promyelocytic leukemia

1 reference

https://api.crossref.org/works/10.1016%2FS1521-6926%2803%2900062-8

7 January 2021

Acute leukemia with promyelocytic features in PML/RARalpha transgenic mice

1 reference

https://api.crossref.org/works/10.1016%2FS1521-6926%2803%2900062-8

7 January 2021

A PMLRARalpha transgene initiates murine acute promyelocytic leukemia

1 reference

https://api.crossref.org/works/10.1016%2FS1521-6926%2803%2900062-8

7 January 2021

Alterations of the FLT3 gene in acute promyelocytic leukemia: association with diagnostic characteristics and analysis of clinical outcome in patients treated with the Italian AIDA protocol

1 reference

https://api.crossref.org/works/10.1016%2FS1521-6926%2803%2900062-8

7 January 2021

The presence of a FLT3 internal tandem duplication in patients with acute myeloid leukemia (AML) adds important prognostic information to cytogenetic risk group and response to the first cycle of chemotherapy: analysis of 854 patients from the Unite

1 reference

https://api.crossref.org/works/10.1016%2FS1521-6926%2803%2900062-8

7 January 2021

PML/RARalpha and FLT3-ITD induce an APL-like disease in a mouse model

1 reference

https://api.crossref.org/works/10.1016%2FS1521-6926%2803%2900062-8

7 January 2021

Distinct interactions of PML-RARalpha and PLZF-RARalpha with co-repressors determine differential responses to RA in APL.

1 reference

https://api.crossref.org/works/10.1016%2FS1521-6926%2803%2900062-8

7 January 2021

Retinoic acid and arsenic synergize to eradicate leukemic cells in a mouse model of acute promyelocytic leukemia

1 reference

https://api.crossref.org/works/10.1016%2FS1521-6926%2803%2900062-8

7 January 2021

Retinoic acid (RA) and As2O3 treatment in transgenic models of acute promyelocytic leukemia (APL) unravel the distinct nature of the leukemogenic process induced by the PML-RARalpha and PLZF-RARalpha oncoproteins

1 reference

https://api.crossref.org/works/10.1016%2FS1521-6926%2803%2900062-8

7 January 2021

Rearrangements of the retinoic acid receptor alpha and promyelocytic leukemia zinc finger genes resulting from t(11;17)(q23;q21) in a patient with acute promyelocytic leukemia

1 reference

https://api.crossref.org/works/10.1016%2FS1521-6926%2803%2900062-8

7 January 2021

Acute promyelocytic leukaemia with t(11;17)(q23;q12-21) and a good initial response to prolonged ATRA and combination chemotherapy

1 reference

https://api.crossref.org/works/10.1016%2FS1521-6926%2803%2900062-8

7 January 2021

Complete remission through blast cell differentiation in PLZF/RARalpha-positive acute promyelocytic leukemia: in vitro and in vivo studies

1 reference

https://api.crossref.org/works/10.1016%2FS1521-6926%2803%2900062-8

7 January 2021

Sequence-specific DNA binding and transcriptional regulation by the promyelocytic leukemia zinc finger protein.

1 reference

https://api.crossref.org/works/10.1016%2FS1521-6926%2803%2900062-8

7 January 2021

The RAR alpha-PLZF chimera associated with Acute Promyelocytic Leukemia has retained a sequence-specific DNA-binding domain.

1 reference

https://api.crossref.org/works/10.1016%2FS1521-6926%2803%2900062-8

7 January 2021

The promyelocytic leukemia zinc finger (PLZF) protein binds DNA in a high molecular weight complex associated with cdc2 kinase

1 reference

https://api.crossref.org/works/10.1016%2FS1521-6926%2803%2900062-8

7 January 2021

The POZ domain: a conserved protein-protein interaction motif

1 reference

https://api.crossref.org/works/10.1016%2FS1521-6926%2803%2900062-8

7 January 2021

Transcriptional repressor ZF5 identifies a new conserved domain in zinc finger proteins

1 reference

https://api.crossref.org/works/10.1016%2FS1521-6926%2803%2900062-8

7 January 2021

BCL-6, a POZ/zinc-finger protein, is a sequence-specific transcriptional repressor

1 reference

https://api.crossref.org/works/10.1016%2FS1521-6926%2803%2900062-8

7 January 2021

Leukemia-associated retinoic acid receptor alpha fusion partners, PML and PLZF, heterodimerize and colocalize to nuclear bodies

1 reference

https://api.crossref.org/works/10.1016%2FS1521-6926%2803%2900062-8

7 January 2021

The acute promyelocytic leukaemia specific PML and PLZF proteins localize to adjacent and functionally distinct nuclear bodies

1 reference

https://api.crossref.org/works/10.1016%2FS1521-6926%2803%2900062-8

7 January 2021

Deregulation of NPM and PLZF in a variant t(5;17) case of acute promyelocytic leukemia.

1 reference

https://api.crossref.org/works/10.1016%2FS1521-6926%2803%2900062-8

7 January 2021

The acute promyelocytic leukemia-associated protein, promyelocytic leukemia zinc finger, regulates 1,25-dihydroxyvitamin D(3)-induced monocytic differentiation of U937 cells through a physical interaction with vitamin D(3) receptor

1 reference

https://api.crossref.org/works/10.1016%2FS1521-6926%2803%2900062-8

7 January 2021

PLZF induces megakaryocytic development, activates Tpo receptor expression and interacts with GATA1 protein

1 reference

https://api.crossref.org/works/10.1016%2FS1521-6926%2803%2900062-8

7 January 2021

Expression of the zinc-finger gene PLZF at rhombomere boundaries in the vertebrate hindbrain

1 reference

https://api.crossref.org/works/10.1016%2FS1521-6926%2803%2900062-8

7 January 2021

Plzf regulates limb and axial skeletal patterning

1 reference

https://api.crossref.org/works/10.1016%2FS1521-6926%2803%2900062-8

7 January 2021

Plzf mediates transcriptional repression of HoxD gene expression through chromatin remodeling

1 reference

https://api.crossref.org/works/10.1016%2FS1521-6926%2803%2900062-8

7 January 2021

Oncogenic transcription factors in the human acute leukemias

1 reference

https://api.crossref.org/works/10.1016%2FS1521-6926%2803%2900062-8

7 January 2021

Altered Hox expression and segmental identity in Mll-mutant mice

1 reference

https://api.crossref.org/works/10.1016%2FS1521-6926%2803%2900062-8

7 January 2021

The promyelocytic leukemia zinc finger protein affects myeloid cell growth, differentiation, and apoptosis

1 reference

https://api.crossref.org/works/10.1016%2FS1521-6926%2803%2900062-8

7 January 2021

Leukemia translocation protein PLZF inhibits cell growth and expression of cyclin A.

1 reference

https://api.crossref.org/works/10.1016%2FS1521-6926%2803%2900062-8

7 January 2021

Opposite effects of the acute promyelocytic leukemia PML-retinoic acid receptor alpha (RAR alpha) and PLZF-RAR alpha fusion proteins on retinoic acid signalling.

1 reference

https://api.crossref.org/works/10.1016%2FS1521-6926%2803%2900062-8

7 January 2021

Histone deacetylase associated with mSin3A mediates repression by the acute promyelocytic leukemia-associated PLZF protein

1 reference

https://api.crossref.org/works/10.1016%2FS1521-6926%2803%2900062-8

7 January 2021

Fusion proteins of the retinoic acid receptor-alpha recruit histone deacetylase in promyelocytic leukaemia

1 reference

https://api.crossref.org/works/10.1016%2FS1521-6926%2803%2900062-8

7 January 2021

SMRT corepressor interacts with PLZF and with the PML-retinoic acid receptor alpha (RARalpha) and PLZF-RARalpha oncoproteins associated with acute promyelocytic leukemia

1 reference

https://api.crossref.org/works/10.1016%2FS1521-6926%2803%2900062-8

7 January 2021

Role of the histone deacetylase complex in acute promyelocytic leukaemia

1 reference

https://api.crossref.org/works/10.1016%2FS1521-6926%2803%2900062-8

7 January 2021

Components of the SMRT corepressor complex exhibit distinctive interactions with the POZ domain oncoproteins PLZF, PLZF-RARalpha, and BCL-6

1 reference

https://api.crossref.org/works/10.1016%2FS1521-6926%2803%2900062-8

7 January 2021

Identification of a nuclear domain with deacetylase activity.

1 reference

https://api.crossref.org/works/10.1016%2FS1521-6926%2803%2900062-8

7 January 2021

The ETO protein disrupted in t(8;21)-associated acute myeloid leukemia is a corepressor for the promyelocytic leukemia zinc finger protein

1 reference

https://api.crossref.org/works/10.1016%2FS1521-6926%2803%2900062-8

7 January 2021

In-depth mutational analysis of the promyelocytic leukemia zinc finger BTB/POZ domain reveals motifs and residues required for biological and transcriptional functions

1 reference

https://api.crossref.org/works/10.1016%2FS1521-6926%2803%2900062-8

7 January 2021

Critical residues within the BTB domain of PLZF and Bcl-6 modulate interaction with corepressors.

1 reference

https://api.crossref.org/works/10.1016%2FS1521-6926%2803%2900062-8

7 January 2021

Promoter context- and response element-dependent specificity of the transcriptional activation and modulating functions of retinoic acid receptors

1 reference

https://api.crossref.org/works/10.1016%2FS1521-6926%2803%2900062-8

7 January 2021

The impact of differential binding of wild-type RARalpha, PML-, PLZF- and NPM-RARalpha fusion proteins towards transcriptional co-activator, RIP-140, on retinoic acid responses in acute promyelocytic leukemia

1 reference

https://api.crossref.org/works/10.1016%2FS1521-6926%2803%2900062-8

7 January 2021

PLZF-RAR alpha fusion proteins generated from the variant t(11;17)(q23;q21) translocation in acute promyelocytic leukemia inhibit ligand-dependent transactivation of wild-type retinoic acid receptors

1 reference

https://api.crossref.org/works/10.1016%2FS1521-6926%2803%2900062-8

7 January 2021

Retinoic acid, but not arsenic trioxide, degrades the PLZF/RARalpha fusion protein, without inducing terminal differentiation or apoptosis, in a RA-therapy resistant t(11;17)(q23;q21) APL patient

1 reference

https://api.crossref.org/works/10.1016%2FS1521-6926%2803%2900062-8

7 January 2021

Distinct leukemia phenotypes in transgenic mice and different corepressor interactions generated by promyelocytic leukemia variant fusion genes PLZF-RARalpha and NPM-RARalpha

1 reference

https://api.crossref.org/works/10.1016%2FS1521-6926%2803%2900062-8

7 January 2021

Fusion of a kinase gene, ALK, to a nucleolar protein gene, NPM, in non-Hodgkin's lymphoma

1 reference

https://api.crossref.org/works/10.1016%2FS1521-6926%2803%2900062-8

7 January 2021

Molecular characterization of ALK, a receptor tyrosine kinase expressed specifically in the nervous system

1 reference

https://api.crossref.org/works/10.1016%2FS1521-6926%2803%2900062-8

7 January 2021

The morphological relationship in electron microscopy between NOR-silver proteins and intranucleolar chromatin

1 reference

https://api.crossref.org/works/10.1016%2FS1521-6926%2803%2900062-8

7 January 2021

Nucleophosmin/B23 (NPM) oligomer is a major and stable entity in HeLa cells

1 reference

https://api.crossref.org/works/10.1016%2FS1521-6926%2803%2900062-8

7 January 2021

Immunofluorescence studies on proteins B23 and C23 in nucleoli of human lymphocytes

1 reference

https://api.crossref.org/works/10.1016%2FS1521-6926%2803%2900062-8

7 January 2021

Interaction of nucleolar phosphoprotein B23 with nucleic acids

1 reference

https://api.crossref.org/works/10.1016%2FS1521-6926%2803%2900062-8

7 January 2021

Major nucleolar proteins shuttle between nucleus and cytoplasm

1 reference

https://api.crossref.org/works/10.1016%2FS1521-6926%2803%2900062-8

7 January 2021

Nucleolar protein B23 stimulates nuclear import of the HIV-1 Rev protein and NLS-conjugated albumin.

1 reference

https://api.crossref.org/works/10.1016%2FS1521-6926%2803%2900062-8

7 January 2021

Nucleophosmin/B23 is a target of CDK2/cyclin E in centrosome duplication

1 reference

https://api.crossref.org/works/10.1016%2FS1521-6926%2803%2900062-8

7 January 2021

The role of nucleophosmin in centrosome duplication

1 reference

https://api.crossref.org/works/10.1016%2FS1521-6926%2803%2900062-8

7 January 2021

Role of protein phosphorylation in post-translational regulation of protein B23 during programmed cell death in the prostate gland

1 reference

https://api.crossref.org/works/10.1016%2FS1521-6926%2803%2900062-8

7 January 2021

A study of correlation between NPM-translocation and apoptosis in cells induced by daunomycin

1 reference

https://api.crossref.org/works/10.1016%2FS1521-6926%2803%2900062-8

7 January 2021

Effects of actinomycin D analogs on nucleolar phosphoprotein B23 (37,000 daltons/pI 5.1).

1 reference

https://api.crossref.org/works/10.1016%2FS1521-6926%2803%2900062-8

7 January 2021

Translocation of nucleolar phosphoprotein B23 (37 kDa/pI 5.1) induced by selective inhibitors of ribosome synthesis

1 reference

https://api.crossref.org/works/10.1016%2FS1521-6926%2803%2900062-8

7 January 2021

Nucleophosmin regulates the stability and transcriptional activity of p53

1 reference

https://api.crossref.org/works/10.1016%2FS1521-6926%2803%2900062-8

7 January 2021

Oncogenic ras provokes premature cell senescence associated with accumulation of p53 and p16INK4a

1 reference

https://api.crossref.org/works/10.1016%2FS1521-6926%2803%2900062-8

7 January 2021

Differentiation of t(5;17) variant acute promyelocytic leukemic blasts by all-trans retinoic acid

1 reference

https://api.crossref.org/works/10.1016%2FS1521-6926%2803%2900062-8

7 January 2021

Primary structure of NuMA, an intranuclear protein that defines a novel pathway for segregation of proteins at mitosis

1 reference

https://api.crossref.org/works/10.1016%2FS1521-6926%2803%2900062-8

7 January 2021

NuMA, a nuclear protein involved in mitosis and nuclear reformation.

1 reference

https://api.crossref.org/works/10.1016%2FS1521-6926%2803%2900062-8

7 January 2021

Assignment of the nuclear mitotic apparatus protein NuMA gene to human chromosome 11q13

1 reference

https://api.crossref.org/works/10.1016%2FS1521-6926%2803%2900062-8

7 January 2021

NuMA is required for the proper completion of mitosis.

1 reference

https://api.crossref.org/works/10.1016%2FS1521-6926%2803%2900062-8

7 January 2021

Essential role for the dimerization domain of NuMA-RARalpha in its oncogenic activities and localization to NuMA sites within the nucleus

1 reference

https://api.crossref.org/works/10.1016%2FS1521-6926%2803%2900062-8

7 January 2021

Stats: transcriptional control and biological impact

1 reference

https://api.crossref.org/works/10.1016%2FS1521-6926%2803%2900062-8

7 January 2021

Erythropoietin-induced erythroid differentiation of the human erythroleukemia cell line TF-1 correlates with impaired STAT5 activation

1 reference

https://api.crossref.org/works/10.1016%2FS1521-6926%2803%2900062-8

7 January 2021

Suppression of interleukin-3-induced gene expression by a C-terminal truncated Stat5: role of Stat5 in proliferation.

1 reference

https://api.crossref.org/works/10.1016%2FS1521-6926%2803%2900062-8

7 January 2021

The role of Stat5a and Stat5b in signaling by IL-2 family cytokines

1 reference

https://api.crossref.org/works/10.1016%2FS1521-6926%2803%2900062-8

7 January 2021

Stat5a and Stat5b proteins have essential and nonessential, or redundant, roles in cytokine responses

1 reference

https://api.crossref.org/works/10.1016%2FS1521-6926%2803%2900062-8

7 January 2021

Stat5b is essential for natural killer cell-mediated proliferation and cytolytic activity

1 reference

https://api.crossref.org/works/10.1016%2FS1521-6926%2803%2900062-8

7 January 2021

Signal transducer and activator of transcription (STAT)5 activation by BCR/ABL is dependent on intact Src homology (SH)3 and SH2 domains of BCR/ABL and is required for leukemogenesis

1 reference

https://api.crossref.org/works/10.1016%2FS1521-6926%2803%2900062-8

7 January 2021

Constitutively active STAT5 variants induce growth and survival of hematopoietic cells through a PI 3-kinase/Akt dependent pathway.

1 reference

https://api.crossref.org/works/10.1016%2FS1521-6926%2803%2900062-8

7 January 2021

Functional association of Nmi with Stat5 and Stat1 in IL-2- and IFNgamma-mediated signaling

1 reference

https://api.crossref.org/works/10.1016%2FS1521-6926%2803%2900062-8

7 January 2021

Interactions of STAT5b-RARalpha, a novel acute promyelocytic leukemia fusion protein, with retinoic acid receptor and STAT3 signaling pathways

1 reference

https://api.crossref.org/works/10.1016%2FS1521-6926%2803%2900062-8

7 January 2021