UTX and UTY demonstrate histone demethylase-independent function in mouse embryonic development (Q28484095)

Retinoblastoma binding protein 5, histone lysine methyltransferase complex subunit

1 reference

Lysine (K)-specific demethylase 6A

1 reference

Histone demethylase UTY

1 reference

NK2 homeobox 5

1 reference

1 reference

T-box 5

1 reference

Creative Commons Attribution 4.0 International

Toru Sengoku

2

0 references

Shigeyuki Yokoyama

object named as

Shigeyuki Yokoyama

series ordinal

3

0 references

Terry Magnuson

series ordinal

4

object named as

Terry Magnuson

0 references

author name string

Karl B Shpargel

series ordinal

1

0 references

language of work or name

English

0 references

publication date

September 2012

0 references

published in

PLOS Genetics

0 references

volume

8

0 references

issue

9

0 references

page(s)

e1002964

0 references

copyright license

start time

27 September 2012

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

0 references

describes a project that uses

ImageJ

1 reference

Europe PubMed Central

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC3459986/fullTextXML

based on heuristic

inferred from PubMed Central ID database lookup

cites work

The C. elegans H3K27 demethylase UTX-1 is essential for normal development, independent of its enzymatic activity

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Structural basis for histone H3 Lys 27 demethylation by UTX/KDM6A

19 March 2017

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EZH1 and EZH2 cogovern histone H3K27 trimethylation and are essential for hair follicle homeostasis and wound repair

19 March 2017

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c-Myc regulates transcriptional pause release

19 March 2017

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The histone demethylase UTX enables RB-dependent cell fate control

19 March 2017

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Histone demethylase JMJD3 contributes to epigenetic control of INK4a/ARF by oncogenic RAS

19 March 2017

1 reference

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The H3K27me3 demethylase JMJD3 contributes to the activation of the INK4A-ARF locus in response to oncogene- and stress-induced senescence

19 March 2017

1 reference

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EZH1 mediates methylation on histone H3 lysine 27 and complements EZH2 in maintaining stem cell identity and executing pluripotency

19 March 2017

1 reference

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Genomewide analysis of PRC1 and PRC2 occupancy identifies two classes of bivalent domains

19 March 2017

1 reference

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The histone H3 lysine 27-specific demethylase Jmjd3 is required for neural commitment

19 March 2017

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19 March 2017

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Mapping and quantifying mammalian transcriptomes by RNA-Seq

19 March 2017

1 reference

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Identification of JmjC domain-containing UTX and JMJD3 as histone H3 lysine 27 demethylases

19 March 2017

1 reference

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A histone H3 lysine 27 demethylase regulates animal posterior development

19 March 2017

1 reference

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The histone H3 lysine-27 demethylase Jmjd3 links inflammation to inhibition of polycomb-mediated gene silencing

19 March 2017

1 reference

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SOX3 activity during pharyngeal segmentation is required for craniofacial morphogenesis

19 March 2017

1 reference

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UTX and JMJD3 are histone H3K27 demethylases involved in HOX gene regulation and development

19 March 2017

1 reference

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PTIP associates with MLL3- and MLL4-containing histone H3 lysine 4 methyltransferase complex

19 March 2017

1 reference

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RBP2 belongs to a family of demethylases, specific for tri-and dimethylated lysine 4 on histone 3

19 March 2017

1 reference

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The X-linked mental retardation gene SMCX/JARID1C defines a family of histone H3 lysine 4 demethylases

19 March 2017

1 reference

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A bivalent chromatin structure marks key developmental genes in embryonic stem cells

19 March 2017

1 reference

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Control of developmental regulators by Polycomb in human embryonic stem cells

19 March 2017

1 reference

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The murine polycomb group protein Eed is required for global histone H3 lysine-27 methylation

19 March 2017

1 reference

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Suz12 is essential for mouse development and for EZH2 histone methyltransferase activity

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3459986

SUZ12 is required for both the histone methyltransferase activity and the silencing function of the EED-EZH2 complex

19 March 2017

1 reference

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Sox3 Is Required for Gonadal Function, but Not Sex Determination, in Males and Females

19 March 2017

1 reference

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GATA4 mutations cause human congenital heart defects and reveal an interaction with TBX5

19 March 2017

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Histone methyltransferase activity associated with a human multiprotein complex containing the Enhancer of Zeste protein

19 March 2017

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Role of histone H3 lysine 27 methylation in Polycomb-group silencing

19 March 2017

1 reference

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Coilin forms the bridge between Cajal bodies and SMN, the spinal muscular atrophy protein

19 March 2017

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Characterization of genes encoding translation initiation factor eIF-2gamma in mouse and human: sex chromosome localization, escape from X-inactivation and evolution

19 March 2017

1 reference

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Zfx mutation results in small animal size and reduced germ cell number in male and female mice

19 March 2017

1 reference

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UTX, a histone H3-lysine 27 demethylase, acts as a critical switch to activate the cardiac developmental program

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3459986

UTX mediates demethylation of H3K27me3 at muscle-specific genes during myogenesis

19 March 2017

1 reference

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Ezh2 orchestrates gene expression for the stepwise differentiation of tissue-specific stem cells

19 March 2017

1 reference

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SOX3 is required during the formation of the hypothalamo-pituitary axis

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3459986

Residual Cajal bodies in coilin knockout mice fail to recruit Sm snRNPs and SMN, the spinal muscular atrophy gene product

19 March 2017

1 reference

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The Polycomb complex PRC2 and its mark in life

19 March 2017

1 reference

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Polycomb complexes repress developmental regulators in murine embryonic stem cells

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3459986

Genome-wide mapping of Polycomb target genes unravels their roles in cell fate transitions

7 April 2017

1 reference

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Chromatin signatures of pluripotent cell lines

7 April 2017

1 reference

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The diverse functions of histone lysine methylation

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3459986

Histone methyltransferase activity of a Drosophila Polycomb group repressor complex

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3459986

Drosophila enhancer of Zeste/ESC complexes have a histone H3 methyltransferase activity that marks chromosomal Polycomb sites

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3459986

The polycomb-group gene Ezh2 is required for early mouse development

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3459986

The histone H3 Lys 27 demethylase JMJD3 regulates gene expression by impacting transcriptional elongation

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3459986

Histone demethylase UTX and chromatin remodeler BRM bind directly to CBP and modulate acetylation of histone H3 lysine 27.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3459986

Jmjd3 and UTX play a demethylase-independent role in chromatin remodeling to regulate T-box family member-dependent gene expression

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3459986

Global survey of escape from X inactivation by RNA-sequencing in mouse

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3459986

A mutation in the mouse Amelx tri-tyrosyl domain results in impaired secretion of amelogenin and phenocopies human X-linked amelogenesis imperfecta

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3459986

Jmjd3 contributes to the control of gene expression in LPS-activated macrophages

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3459986

Transcription factor Zfx controls BCR-induced proliferation and survival of B lymphocytes

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3459986

Targeted inactivation of MLL3 histone H3-Lys-4 methyltransferase activity in the mouse reveals vital roles for MLL3 in adipogenesis

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3459986

Ezh1 and Ezh2 maintain repressive chromatin through different mechanisms

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3459986

Sex-specific differences in expression of histone demethylases Utx and Uty in mouse brain and neurons

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3459986

Demethylation of H3K27 regulates polycomb recruitment and H2A ubiquitination

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3459986

Generation of a germ cell-specific mouse transgenic Cre line, Vasa-Cre

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3459986

Zfx controls the self-renewal of embryonic and hematopoietic stem cells.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3459986

Physical and functional association of a trimethyl H3K4 demethylase and Ring6a/MBLR, a polycomb-like protein

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3459986

A proposed path by which genes common to mammalian X and Y chromosomes evolve to become X inactivated

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3459986

The UTX gene escapes X inactivation in mice and humans

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3459986

Developmental stage-specific regulation of atrial natriuretic factor gene transcription in cardiac cells

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3459986

A novel X gene with a widely transcribed Y-linked homologue escapes X-inactivation in mouse and human.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3459986

Inactivation of the Zfx gene on the mouse X chromosome

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3459986

Control of differentiation in a self-renewing mammalian tissue by the histone demethylase JMJD3

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3459986

Bmp2 transcription in osteoblast progenitors is regulated by a distant 3' enhancer located 156.3 kilobases from the promoter

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3459986

The Jmjd3-Irf4 axis regulates M2 macrophage polarization and host responses against helminth infection

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3459986

Polycomb repressive complex 2 is dispensable for maintenance of embryonic stem cell pluripotency

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3459986

The trithorax-group gene in Drosophila little imaginal discs encodes a trimethylated histone H3 Lys4 demethylase.

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3459986

Efficient gene modulation in mouse epiblast using a Sox2Cre transgenic mouse strain

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3459986

The eed mutation disrupts anterior mesoderm production in mice

27 November 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/23028370

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Extraction, purification and analysis of histones

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/23028370

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1371/JOURNAL.PGEN.1002964

1 reference

1 reference

1 reference

PubMed publication ID

23028370

1 reference