Positive and Negative Roles of p85α and p85β Regulatory Subunits of Phosphoinositide 3-Kinase in Insulin Signaling (Q28506865)

Continued use of retracted papers: Temporal trends in citations and (lack of) awareness of retractions shown in citation contexts in biomedicine

title

Positive and negative roles of p85 alpha and p85 beta regulatory subunits of phosphoinositide 3-kinase in insulin signaling (English)

1 reference

24 January 2017

Positive and Negative Roles of p85α and p85β Regulatory Subunits of Phosphoinositide 3-Kinase in Insulin Signaling (English)

1 reference

https://api.crossref.org/works/10.1074/JBC.M305602200

13 March 2024

1 reference

1 reference

https://api.crossref.org/works/10.1074/JBC.M305602200

13 March 2024

1 reference

https://api.crossref.org/works/10.1074/JBC.M305602200

13 March 2024

4

Mathias Fasshauer

1 reference

24 January 2017

1

Kohjiro Ueki

1 reference

24 January 2017

8

C. Ronald Kahn

1 reference

24 January 2017

7

Lewis C. Cantley

1 reference

Europe PubMed Central

PubMed ID

14504291

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A14504291

13 March 2024

author name string

David A. Fruman

2

1 reference

24 January 2017

Claudine M. Yballe

3

1 reference

24 January 2017

Johannes Klein

5

1 reference

24 January 2017

Tomoichiro Asano

6

1 reference

24 January 2017

language of work or name

English

0 references

publication date

28 November 2003

1 reference

24 January 2017

22 September 2003

1 reference

Europe PubMed Central

PubMed ID

14504291

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A14504291

full work available at URL

13 March 2024

http://www.jbc.org/content/278/48/48453.full.pdf

file format

Portable Document Format

online access status

open access

1 reference

Europe PubMed Central

PubMed ID

14504291

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A14504291

https://api.elsevier.com/content/article/PII:S0021925820758837?httpAccept=text/xml

13 March 2024

1 reference

https://api.crossref.org/works/10.1074/JBC.M305602200

https://api.elsevier.com/content/article/PII:S0021925820758837?httpAccept=text/plain

13 March 2024

1 reference

https://api.crossref.org/works/10.1074/JBC.M305602200

https://syndication.highwire.org/content/doi/10.1074/jbc.M305602200

13 March 2024

1 reference

https://api.crossref.org/works/10.1074/JBC.M305602200

Journal of Biological Chemistry

13 March 2024

published in

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24 January 2017

278

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24 January 2017

48453–48466

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24 January 2017

48

1 reference

24 January 2017

Phosphoinositide 3-kinase: the key switch mechanism in insulin signalling

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M305602200

Protein-protein interaction in insulin signaling and the molecular mechanisms of insulin resistance

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M305602200

Protein kinase B (c-Akt): a multifunctional mediator of phosphatidylinositol 3-kinase activation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M305602200

Characterization of two 85 kd proteins that associate with receptor tyrosine kinases, middle-T/pp60c-src complexes, and PI3-kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M305602200

Insulin receptor substrate 1 binds two novel splice variants of the regulatory subunit of phosphatidylinositol 3-kinase in muscle and brain

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M305602200

Structural organization and alternative splicing of the murine phosphoinositide 3-kinase p85 alpha gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M305602200

p85alpha gene generates three isoforms of regulatory subunit for phosphatidylinositol 3-kinase (PI 3-Kinase), p50alpha, p55alpha, and p85alpha, with different PI 3-kinase activity elevating responses to insulin

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M305602200

The structure and function of p55PIK reveal a new regulatory subunit for phosphatidylinositol 3-kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M305602200

Molecular balance between the regulatory and catalytic subunits of phosphoinositide 3-kinase regulates cell signaling and survival.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M305602200

Increased insulin sensitivity in mice lacking p85beta subunit of phosphoinositide 3-kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M305602200

Increased insulin sensitivity and hypoglycaemia in mice lacking the p85 alpha subunit of phosphoinositide 3-kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M305602200

Impaired B cell development and proliferation in absence of phosphoinositide 3-kinase p85alpha.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M305602200

Essential role of insulin receptor substrate 1 in differentiation of brown adipocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M305602200

The fat-derived hormone adiponectin reverses insulin resistance associated with both lipoatrophy and obesity

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M305602200

Potential role of protein kinase B in insulin-induced glucose transport, glycogen synthesis, and protein synthesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M305602200

Positive and negative regulation of phosphoinositide 3-kinase-dependent signaling pathways by three different gene products of the p85alpha regulatory subunit

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M305602200

Posttranscriptional control of adipocyte differentiation through activation of phosphoinositide 3-kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M305602200

Essential role of insulin receptor substrate-2 in insulin stimulation of Glut4 translocation and glucose uptake in brown adipocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M305602200

Regulation of the p85/p110 phosphatidylinositol 3'-kinase: stabilization and inhibition of the p110alpha catalytic subunit by the p85 regulatory subunit

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M305602200

Phosphatidylinositol 3-kinase activation is required for insulin stimulation of pp70 S6 kinase, DNA synthesis, and glucose transporter translocation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M305602200

The activation of glycogen synthase by insulin switches from kinase inhibition to phosphatase activation during adipogenesis in 3T3-L1 cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M305602200

Overexpression of SH2-containing inositol phosphatase 2 results in negative regulation of insulin-induced metabolic actions in 3T3-L1 adipocytes via its 5'-phosphatase catalytic activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M305602200

Cellular survival: a play in three Akts

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M305602200

Akt promotes cell survival by phosphorylating and inhibiting a Forkhead transcription factor

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M305602200

The small GTP-binding proteins Rac1 and Cdc42 regulate the activity of the JNK/SAPK signaling pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M305602200

Selective activation of the JNK signaling cascade and c-Jun transcriptional activity by the small GTPases Rac and Cdc42Hs

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M305602200

MEK kinases are regulated by EGF and selectively interact with Rac/Cdc42

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M305602200

The Ras/Rac1/Cdc42/SEK/JNK/c-Jun cascade is a key pathway by which agonists stimulate DNA synthesis in primary cultures of rat hepatocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M305602200

Role of substrates and products of PI 3-kinase in regulating activation of Rac-related guanosine triphosphatases by Vav

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M305602200

The c-Jun NH(2)-terminal kinase promotes insulin resistance during association with insulin receptor substrate-1 and phosphorylation of Ser(307)

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M305602200

c-Jun N-terminal kinase (JNK) mediates feedback inhibition of the insulin signaling cascade

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M305602200

A central role for JNK in obesity and insulin resistance

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M305602200

1-Phosphatidylinositol 3-kinase activity is required for insulin-stimulated glucose transport but not for RAS activation in CHO cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M305602200

Ras-independent and wortmannin-sensitive activation of glycogen synthase by insulin in Chinese hamster ovary cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M305602200

The adipocyte-secreted protein Acrp30 enhances hepatic insulin action

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M305602200

Proteolytic cleavage product of 30-kDa adipocyte complement-related protein increases fatty acid oxidation in muscle and causes weight loss in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M305602200

Inhibition of glycogen synthase kinase-3 by insulin mediated by protein kinase B

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M305602200

Expression of a constitutively active Akt Ser/Thr kinase in 3T3-L1 adipocytes stimulates glucose uptake and glucose transporter 4 translocation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M305602200

Insulin resistance and a diabetes mellitus-like syndrome in mice lacking the protein kinase Akt2 (PKB beta)

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M305602200

Requirement for activation of the serine-threonine kinase Akt (protein kinase B) in insulin stimulation of protein synthesis but not of glucose transport

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M305602200

Akt phosphorylation of BAD couples survival signals to the cell-intrinsic death machinery

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M305602200

Cell survival promoted by the Ras-MAPK signaling pathway by transcription-dependent and -independent mechanisms

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M305602200

The sentrin-conjugating enzyme mUbc9 interacts with GLUT4 and GLUT1 glucose transporters and regulates transporter levels in skeletal muscle cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M305602200

Phosphatidylinositol 3-kinase p85 adaptor function in T-cells. Co-stimulation and regulation of cytokine transcription independent of associated p110.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M305602200

Activation of the Ras Mitogen-activated Protein Kinase-Ribosomal Protein Kinase Pathway Is Not Required for the Repression of Phosphoenolpyruvate Carboxykinase Gene Transcription by Insulin

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M305602200

The molecular mechanism by which insulin stimulates glycogen synthesis in mammalian skeletal muscle

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M305602200