Glutathione-S-transferase P1 is a critical regulator of Cdk5 kinase activity (Q28565510)

31 January 2017

title

Glutathione-S-transferase P1 is a critical regulator of Cdk5 kinase activity (English)

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31 January 2017

Kai-Hui Sun

1

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31 January 2017

Kuei-Hua Chang

2

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31 January 2017

Sara Clawson

3

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31 January 2017

Soumitra Ghosh

4

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31 January 2017

Hamid Mirzaei

5

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31 January 2017

Fred Regnier

6

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31 January 2017

Kavita Shah

7

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31 January 2017

language of work or name

English

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publication date

1 September 2011

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Journal of Neurochemistry

31 January 2017

published in

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31 January 2017

volume

118

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31 January 2017

issue

5

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31 January 2017

page(s)

902–914

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Regulation of JNK signaling by GSTp

31 January 2017

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Cyclin I activates Cdk5 and regulates expression of Bcl-2 and Bcl-XL in postmitotic mouse cells

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Aberrant Cdk5 activation by p25 triggers pathological events leading to neurodegeneration and neurofibrillary tangles

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Cyclin-dependent kinase 5 is a regulator of podocyte differentiation, proliferation, and morphology

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Glutathione transferases

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Regulation and role of cyclin-dependent kinase activity in neuronal survival and death

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Cyclin-dependent kinase 5 modulates the transcriptional activity of the mineralocorticoid receptor and regulates expression of brain-derived neurotrophic factor

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Elevated neuronal Cdc2-like kinase activity in the Alzheimer disease brain.

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Neurotoxicity induces cleavage of p35 to p25 by calpain

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Cdk5 regulates STAT3 activation and cell proliferation in medullary thyroid carcinoma cells

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Decreased glutathione transferase activity in brain and ventricular fluid in Alzheimer's disease

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The proapoptotic function of Noxa in human leukemia cells is regulated by the kinase Cdk5 and by glucose

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Cdk5 phosphorylates Cdh1 and modulates cyclin B1 stability in excitotoxicity

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A lentiviral RNAi library for human and mouse genes applied to an arrayed viral high-content screen

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Targeted disruption of the cyclin-dependent kinase 5 gene results in abnormal corticogenesis, neuronal pathology and perinatal death

21 January 2018

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Cyclin-dependent kinase 5 activity is required for T cell activation and induction of experimental autoimmune encephalomyelitis

21 January 2018

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Conversion of p35 to p25 deregulates Cdk5 activity and promotes neurodegeneration

21 January 2018

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Glutathione S-transferase variants increase susceptibility for late-onset Alzheimer's disease: association study and relationship with apolipoprotein E epsilon4 allele

21 January 2018

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Direct evidence for the formation of a complex between 1-cysteine peroxiredoxin and glutathione S-transferase pi with activity changes in both enzymes

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Extraneuronal roles of cyclin-dependent kinase 5.

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Cdk5 regulates the organization of Nestin and its association with p35

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Cyclin-dependent kinase 5 increases perikaryal neurofilament phosphorylation and inhibits neurofilament axonal transport in response to oxidative stress

21 January 2018

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Identification of glutathione S-transferase pi as a protein involved in Parkinson disease progression

21 January 2018

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Glutathione-S-transferase family of enzymes.

21 January 2018

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Cyclin-dependent kinase 5 activity controls cell motility and metastatic potential of prostate cancer cells

21 January 2018

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Novel genetic tools reveal Cdk5's major role in Golgi fragmentation in Alzheimer's disease

21 January 2018

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Deregulated Cdk5 promotes oxidative stress and mitochondrial dysfunction

21 January 2018

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Direct and indirect roles of cyclin-dependent kinase 5 as an upstream regulator in the c-Jun NH2-terminal kinase cascade: relevance to neurotoxic insults in Alzheimer's disease

21 January 2018

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Brain levels of CDK5 activator p25 are not increased in Alzheimer's or other neurodegenerative diseases with neurofibrillary tangles

21 January 2018

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Cyclin-dependent kinase 5 mediates neurotoxin-induced degradation of the transcription factor myocyte enhancer factor 2.

21 January 2018

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Calpain-mediated degradation of p35 to p25 in postmortem human and rat brains

21 January 2018

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Phosphorylation of ATM by Cdk5 mediates DNA damage signalling and regulates neuronal death

21 January 2018

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A survey of Cdk5 activator p35 and p25 levels in Alzheimer's disease brains

21 January 2018

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Cdk5-dependent regulation of glucose-stimulated insulin secretion.

21 January 2018

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Transcriptional regulation of beta-secretase by p25/cdk5 leads to enhanced amyloidogenic processing

21 January 2018

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Human glutathione S-transferase P1-1 interacts with TRAF2 and regulates TRAF2-ASK1 signals

21 January 2018

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Phosphorylation of p27Kip1 at Thr187 by cyclin-dependent kinase 5 modulates neural stem cell differentiation

21 January 2018

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Neurobiology: p25 protein in neurodegeneration

21 January 2018

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