MEK-ERK-mediated phosphorylation of Mdm2 at Ser-166 in hepatocytes. Mdm2 is activated in response to inhibited Akt signaling (Q28580290)

https://api.crossref.org/works/10.1074%2FJBC.M604953200

Live or let die: the cell's response to p53

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M604953200

p53, the cellular gatekeeper for growth and division

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M604953200

Characterizing the role of MDM2 in diethylnitrosamine induced acute liver damage and development of pre-neoplastic lesions

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M604953200

The mdm-2 oncogene product forms a complex with the p53 protein and inhibits p53-mediated transactivation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M604953200

Mouse bites dogma: how mouse models are changing our views of how P53 is regulated in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M604953200

Cross-talk between Akt, p53 and Mdm2: possible implications for the regulation of apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M604953200

A phosphatidylinositol 3-kinase/Akt pathway promotes translocation of Mdm2 from the cytoplasm to the nucleus

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M604953200

HER-2/neu induces p53 ubiquitination via Akt-mediated MDM2 phosphorylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M604953200

Akt enhances Mdm2-mediated ubiquitination and degradation of p53.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M604953200

HDM2 phosphorylation by MAPKAP kinase 2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M604953200

MEK-ERK signaling controls Hdm2 oncoprotein expression by regulating hdm2 mRNA export to the cytoplasm.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M604953200

The mechanisms of regulation of Hdm2 protein level by serum growth factors

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M604953200

TCDD activates Mdm2 and attenuates the p53 response to DNA damaging agents

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M604953200

HMG-CoA reductase inhibitors, statins, induce phosphorylation of Mdm2 and attenuate the p53 response to DNA damage.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M604953200

Ratliver cells in culture: Effect of storage, long-term culture, and transformation on some enzyme levels

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M604953200

Stabilization of Mdm2 via decreased ubiquitination is mediated by protein kinase B/Akt-dependent phosphorylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M604953200

Cytoplasmic retention of peroxide-activated ERK provides survival in primary cultures of rat hepatocytes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M604953200

Conjugated bile acids promote ERK1/2 and AKT activation via a pertussis toxin-sensitive mechanism in murine and human hepatocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M604953200

p38/RK is essential for stress-induced nuclear responses: JNK/SAPKs and c-Jun/ATF-2 phosphorylation are insufficient

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M604953200

Differentiation stage-specific inhibition of the Raf-MEK-ERK pathway by Akt.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M604953200

Phosphorylation and regulation of Raf by Akt (protein kinase B)

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M604953200

Regulation of Raf by Akt controls growth and differentiation in vascular smooth muscle cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M604953200

Erk1/2 phosphorylation and reactive oxygen species formation via nitric oxide and Akt-1/Raf-1 crosstalk in cultured rat cerebellar granule cells exposed to the organic solvent 1,2,4-trimethylcyclohexane

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M604953200

Leptomycin B inhibition of signal-mediated nuclear export by direct binding to CRM1

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M604953200

Phosphorylation of human p53 at serine 46 determines promoter selection and whether apoptosis is attenuated or amplified.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M604953200

The PI3K inhibitor LY294002 prevents p53 induction by DNA damage and attenuates chemotherapy-induced apoptosis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M604953200

Second nature: biological functions of the Raf-1 "kinase"

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M604953200

Hepatocyte growth factor enhances protein phosphatase Cdc25A inhibitor compound 5-induced hepatoma cell growth inhibition via Akt-mediated MAPK pathway.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M604953200

Negative regulation of the serine/threonine kinase B-Raf by Akt

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M604953200

Rescue of early embryonic lethality in mdm2-deficient mice by deletion of p53

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M604953200

Essential role of B-Raf in ERK activation during extraembryonic development

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M604953200

Mammalian sterile 20-like kinases in tumor suppression: an emerging pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M604953200

PKB binding proteins. Getting in on the Akt.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M604953200

Chronic ethanol intake impairs insulin signaling in rats by disrupting Akt association with the cell membrane. Role of TRB3 in inhibition of Akt/protein kinase B activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M604953200