Toll-like receptor-mediated IRE1α activation as a therapeutic target for inflammatory arthritis (Q28589300)

TNF receptor-associated factor 6

GOA release 2020-03-11

1 reference

GOA release 2020-03-11

author name string

Quan Qiu

1

1 reference

31 January 2017

Ze Zheng

2

1 reference

31 January 2017

Lin Chang

3

1 reference

31 January 2017

Yuan-Si Zhao

4

1 reference

31 January 2017

Can Tan

5

1 reference

31 January 2017

Aditya Dandekar

6

1 reference

31 January 2017

Zheng Zhang

7

1 reference

31 January 2017

Zhenghong Lin

8

1 reference

31 January 2017

Ming Gui

9

1 reference

31 January 2017

Xiu Li

10

1 reference

31 January 2017

Tongshuai Zhang

11

1 reference

31 January 2017

Qingfei Kong

12

1 reference

31 January 2017

Hulun Li

13

1 reference

31 January 2017

Sha Chen

14

1 reference

31 January 2017

An Chen

15

1 reference

31 January 2017

Randal J. Kaufman

16

1 reference

31 January 2017

Wei-Lei Yang

17

1 reference

31 January 2017

Hui-Kuan Lin

18

1 reference

31 January 2017

Donna Zhang

19

1 reference

31 January 2017

Harris Perlman

20

1 reference

31 January 2017

Edward Thorp

21

1 reference

31 January 2017

Kezhong Zhang

22

1 reference

31 January 2017

Deyu Fang

The molecular basis for selective inhibition of unconventional mRNA splicing by an IRE1-binding small molecule

23

1 reference

31 January 2017

language of work or name

English

0 references

publication date

11 September 2013

1 reference

31 January 2017

1 reference

31 January 2017

32

1 reference

31 January 2017

2477–2490

1 reference

31 January 2017

18

1 reference

31 January 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3770952

The unfolded protein response: integrating stress signals through the stress sensor IRE1α

17 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3770952

Endoplasmic reticulum stress and the inflammatory basis of metabolic disease

17 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3770952

A crucial role for RACK1 in the regulation of glucose-stimulated IRE1alpha activation in pancreatic beta cells

17 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3770952

The E3 ligase TRAF6 regulates Akt ubiquitination and activation

17 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3770952

Regulation of hepatic lipogenesis by the transcription factor XBP1

17 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3770952

Modulation of macrophage differentiation and activation by decoy receptor 3

17 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3770952

IRE1 couples endoplasmic reticulum load to secretory capacity by processing the XBP-1 mRNA

17 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3770952

Complementary signaling pathways regulate the unfolded protein response and are required for C. elegans development

17 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3770952

TAK1 is a ubiquitin-dependent kinase of MKK and IKK

17 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3770952

Activation of the IkappaB kinase complex by TRAF6 requires a dimeric ubiquitin-conjugating enzyme complex and a unique polyubiquitin chain

17 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3770952

Coupling of stress in the ER to activation of JNK protein kinases by transmembrane protein kinase IRE1

17 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3770952

Cutting edge: heat shock protein 60 is a putative endogenous ligand of the toll-like receptor-4 complex

17 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3770952

TRAF6 deficiency results in osteopetrosis and defective interleukin-1, CD40, and LPS signaling

17 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3770952

Toll-like receptors and their crosstalk with other innate receptors in infection and immunity

17 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3770952

Metabolic syndrome in rheumatoid arthritis: case control study

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3770952

TLR2 deletion promotes arthritis through reduction of IL-10

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3770952

Thioredoxin-interacting protein mediates ER stress-induced β cell death through initiation of the inflammasome

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3770952

A novel pathogenic role of the ER chaperone GRP78/BiP in rheumatoid arthritis

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3770952

TLR-dependent T cell activation in autoimmunity.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3770952

Cyclin-dependent kinase inhibitor p21, via its C-terminal domain, is essential for resolution of murine inflammatory arthritis

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3770952

High mobility group box protein 1 in complex with lipopolysaccharide or IL-1 promotes an increased inflammatory phenotype in synovial fibroblasts.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3770952

The unfolded protein response and its role in intestinal homeostasis and inflammation.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3770952

Stressed out about obesity: IRE1α-XBP1 in metabolic disorders

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3770952

Dual and opposing roles of the unfolded protein response regulated by IRE1alpha and XBP1 in proinsulin processing and insulin secretion

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3770952

Detecting and quantitating physiological endoplasmic reticulum stress

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3770952

Regulation of innate immunity by signaling pathways emerging from the endoplasmic reticulum

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3770952

Monocytes/macrophages express chemokine receptor CCR9 in rheumatoid arthritis and CCL25 stimulates their differentiation

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3770952

A Phos-tag-based approach reveals the extent of physiological endoplasmic reticulum stress

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3770952

Deficiency of CXCR2, but not other chemokine receptors, attenuates autoantibody-mediated arthritis in a murine model

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3770952

An unfolded protein response is the initial cellular response to the expression of mutant matrilin-3 in a mouse model of multiple epiphyseal dysplasia.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3770952

Integration of ER stress, oxidative stress and the inflammatory response in health and disease

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3770952

TLR activation of the transcription factor XBP1 regulates innate immune responses in macrophages.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3770952

Autophagy induction and CHOP under-expression promotes survival of fibroblasts from rheumatoid arthritis patients under endoplasmic reticulum stress

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3770952

Bim-Bcl-2 homology 3 mimetic therapy is effective at suppressing inflammatory arthritis through the activation of myeloid cell apoptosis

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3770952

HLA-B27 misfolding and spondyloarthropathies.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3770952

IRE1alpha kinase activation modes control alternate endoribonuclease outputs to determine divergent cell fates.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3770952

Regulated Ire1-dependent decay of messenger RNAs in mammalian cells

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3770952

A subcytotoxic dose of subtilase cytotoxin prevents lipopolysaccharide-induced inflammatory responses, depending on its capacity to induce the unfolded protein response

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3770952

Intersection of the unfolded protein response and hepatic lipid metabolism

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3770952

Heat shock protein 96 is elevated in rheumatoid arthritis and activates macrophages primarily via TLR2 signaling

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3770952

Functional aspects of Toll-like receptor/MyD88 signalling during protozoan infection: focus on Toxoplasma gondii

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3770952

Toll-like receptor-mediated induction of type I interferon in plasmacytoid dendritic cells requires the rapamycin-sensitive PI(3)K-mTOR-p70S6K pathway

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3770952

From endoplasmic-reticulum stress to the inflammatory response

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3770952

Plasmacytoid dendritic cells: sensing nucleic acids in viral infection and autoimmune diseases.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3770952

Anti-inflammatory effects of glycyrol isolated from Glycyrrhiza uralensis in LPS-stimulated RAW264.7 macrophages

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3770952

High-mobility group box protein 1 (HMGB1): an alarmin mediating the pathogenesis of rheumatic disease

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3770952

Convergence and amplification of toll-like receptor (TLR) and receptor for advanced glycation end products (RAGE) signaling pathways via high mobility group B1 (HMGB1).

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3770952

TLR-2-mediated induction of vascular endothelial growth factor (VEGF) in cartilage in septic joint disease

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3770952

Decay of endoplasmic reticulum-localized mRNAs during the unfolded protein response.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3770952

The unfolded protein response: a stress signaling pathway critical for health and disease.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3770952

The unfolded protein response sensor IRE1alpha is required at 2 distinct steps in B cell lymphopoiesis.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3770952

Coumarin and isocoumarin as serine protease inhibitors.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3770952

Therapeutic targeting of Toll-like receptors for inflammatory and infectious diseases.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3770952

Colony-stimulating factor-1-dependent macrophages are responsible for IVIG protection in antibody-induced autoimmune disease

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3770952

Expression and regulation of Toll-like receptor 2 in rheumatoid arthritis synovium

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3770952

Mast cells: a cellular link between autoantibodies and inflammatory arthritis

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3770952

Novel signal transduction pathway utilized by extracellular HSP70: role of toll-like receptor (TLR) 2 and TLR4.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3770952

Regulation of protein kinase cascades by protein phosphatase 2A.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3770952

From systemic T cell self-reactivity to organ-specific autoimmune disease via immunoglobulins

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3770952

The unfolded protein response transducer IRE1α prevents ER stress-induced hepatic steatosis

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3770952

Prolonged activation of jun and collagenase genes by tumour necrosis factor-alpha

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3770952

Immunology in China: the past, present and future

3 June 2018

1 reference

https://api.crossref.org/works/10.1038%2FEMBOJ.2013.183

Conditional gene targeting in macrophages and granulocytes using LysMcre mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FEMBOJ.2013.183

The role of FcgammaR signaling in the K/B x N serum transfer model of arthritis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FEMBOJ.2013.183

A transgenic mouse model for monitoring endoplasmic reticulum stress

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FEMBOJ.2013.183

Arthritis critically dependent on innate immune system players

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FEMBOJ.2013.183

Transgenic mouse model for monitoring endoplasmic reticulum stress in vivo.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FEMBOJ.2013.183

Overexpression of toll-like receptors 3 and 4 in synovial tissue from patients with early rheumatoid arthritis: toll-like receptor expression in early and longstanding arthritis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FEMBOJ.2013.183

Anti-arthritic effect of scopoletin, a coumarin compound occurring in Erycibe obtusifolia Benth stems, is associated with decreased angiogenesis in synovium

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FEMBOJ.2013.183

Synergistic induction of CXCL9 and CXCL11 by Toll-like receptor ligands and interferon-gamma in fibroblasts correlates with elevated levels of CXCR3 ligands in septic arthritis synovial fluids.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FEMBOJ.2013.183

Regulation of transcriptional activation domain function by ubiquitin

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FEMBOJ.2013.183

HLA-B27 misfolding in transgenic rats is associated with activation of the unfolded protein response.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FEMBOJ.2013.183

Essential role of neutrophils in the initiation and progression of a murine model of rheumatoid arthritis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FEMBOJ.2013.183

In vitro inhibitory effects of Daphne oleoides ssp. oleoides on inflammatory cytokines and activity-guided isolation of active constituents

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FEMBOJ.2013.183

Identification of small heat shock protein B8 (HSP22) as a novel TLR4 ligand and potential involvement in the pathogenesis of rheumatoid arthritis

21 January 2018

1 reference

12 December 2020

Regulatory effect of daphnetin, a coumarin extracted from Daphne odora, on the balance of Treg and Th17 in collagen-induced arthritis

1 reference

12 December 2020

Antiinflammatory and antioxidant evaluation of novel coumarin derivatives

1 reference

12 December 2020

Differential expression of toll-like receptor 6 on granulocytes and monocytes implicates the role of microorganisms in Behcet's disease etiopathogenesis

1 reference

12 December 2020

Therapeutic efficacy and safety of chaperonin 10 in patients with rheumatoid arthritis: a double-blind randomised trial

1 reference

12 December 2020

Effect of compound IMMLG5521, a novel coumarin derivative, on carrageenan-induced pleurisy in rats

1 reference

12 December 2020

Identifiers

DOI

10.1038/EMBOJ.2013.183

1 reference

release_gpi5abehhjghjcq73hopsjxw64

3952601

Fatcat ID

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/gpi5abehhjghjcq73hopsjxw64

24 November 2022

mapped directly with Wikidata item

3952601

1 reference

1 reference

1 reference