Chikungunya virus: an update on the biology and pathogenesis of this emerging pathogen (Q28599242)

12 June 2017

Chikungunya virus: an update on the biology and pathogenesis of this emerging pathogen (English)

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12 June 2017

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12

Lisa F P Ng

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12 June 2017

Ali Zaid

11

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Andres Merits

object named as

Andres Merits

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5

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Alain Kohl

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7

object named as

Alain Kohl

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12 June 2017

13

Suresh Mahalingam

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12 June 2017

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Jonathan J Miner

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12 June 2017

1

Felicity J Burt

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12 June 2017

4

Deborah J Lenschow

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12 June 2017

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Adam Taylor

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12 June 2017

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Penny A Rudd

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12 June 2017

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Lara J Herrero

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12 June 2017

Weiqiang Chen

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PubMed ID

28159534

12 June 2017

Esther Schnettler

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6

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12 June 2017

31 January 2017

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Lancet Infectious Diseases

12 June 2017

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12 June 2017

e107-e117

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12 June 2017

4

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An epidemic of virus disease in Southern Province, Tanganyika Territory, in 1952-53. I. Clinical features

12 June 2017

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https://api.crossref.org/works/10.1016%2FS1473-3099%2816%2930385-1

7 January 2021

Arthritogenic alphaviruses--an overview

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https://api.crossref.org/works/10.1016%2FS1473-3099%2816%2930385-1

7 January 2021

Chikungunya disease outbreak, Reunion Island.

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https://api.crossref.org/works/10.1016%2FS1473-3099%2816%2930385-1

7 January 2021

Guillain-Barré syndrome complicating a Chikungunya virus infection

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https://api.crossref.org/works/10.1016%2FS1473-3099%2816%2930385-1

7 January 2021

A single mutation in chikungunya virus affects vector specificity and epidemic potential

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https://api.crossref.org/works/10.1016%2FS1473-3099%2816%2930385-1

7 January 2021

Chikungunya: Evolutionary history and recent epidemic spread

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7 January 2021

Infection with chikungunya virus in Italy: an outbreak in a temperate region

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https://api.crossref.org/works/10.1016%2FS1473-3099%2816%2930385-1

7 January 2021

First cases of autochthonous dengue fever and chikungunya fever in France: from bad dream to reality!

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7 January 2021

Chikungunya outbreak in Montpellier, France, September to October 2014.

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7 January 2021

Emergence of chikungunya fever on the French side of Saint Martin island, October to December 2013.

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7 January 2021

Chikungunya in the Americas

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7 January 2021

Chikungunya outbreak in the Caribbean region, December 2013 to March 2014, and the significance for Europe

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7 January 2021

Chikungunya: epidemiology

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https://api.crossref.org/works/10.1016%2FS1473-3099%2816%2930385-1

7 January 2021

Chikungunya virus 3' untranslated region: adaptation to mosquitoes and a population bottleneck as major evolutionary forces

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7 January 2021

Early Events in Chikungunya Virus Infection-From Virus Cell Binding to Membrane Fusion

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https://api.crossref.org/works/10.1016%2FS1473-3099%2816%2930385-1

7 January 2021

Mutations conferring a noncytotoxic phenotype on chikungunya virus replicons compromise enzymatic properties of nonstructural protein 2

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7 January 2021

NTPase and 5'-RNA triphosphatase activities of Chikungunya virus nsP2 protein

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7 January 2021

Functional cross-talk between distant domains of chikungunya virus non-structural protein 2 is decisive for its RNA-modulating activity

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7 January 2021

Evasion of the innate immune response: the Old World alphavirus nsP2 protein induces rapid degradation of Rpb1, a catalytic subunit of RNA polymerase II

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https://api.crossref.org/works/10.1016%2FS1473-3099%2816%2930385-1

7 January 2021

Chikungunya virus nonstructural protein 2 inhibits type I/II interferon-stimulated JAK-STAT signaling

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https://api.crossref.org/works/10.1016%2FS1473-3099%2816%2930385-1

7 January 2021

The C-terminal domain of chikungunya virus nsP2 independently governs viral RNA replication, cytopathicity, and inhibition of interferon signaling

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https://api.crossref.org/works/10.1016%2FS1473-3099%2816%2930385-1

7 January 2021

Chikungunya virus non-structural protein 2-mediated host shut-off disables the unfolded protein response

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7 January 2021

Species-specific impact of the autophagy machinery on Chikungunya virus infection

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https://api.crossref.org/works/10.1016%2FS1473-3099%2816%2930385-1

7 January 2021

The Crystal Structures of Chikungunya and Venezuelan Equine Encephalitis Virus nsP3 Macro Domains Define a Conserved Adenosine Binding Pocket

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7 January 2021

The C-terminal repeat domains of nsP3 from the Old World alphaviruses bind directly to G3BP

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7 January 2021

SH3 domain-mediated recruitment of host cell amphiphysins by alphavirus nsP3 promotes viral RNA replication

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7 January 2021

Mapping of Chikungunya virus interactions with host proteins identified nsP2 as a highly connected viral component

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7 January 2021

Temporal SILAC-based quantitative proteomics identifies host factors involved in chikungunya virus replication.

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7 January 2021

Heat shock protein 90 positively regulates Chikungunya virus replication by stabilizing viral non-structural protein nsP2 during infection

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https://api.crossref.org/works/10.1016%2FS1473-3099%2816%2930385-1

7 January 2021

Chikungunya virus nsP3 & nsP4 interacts with HSP-90 to promote virus replication: HSP-90 inhibitors reduce CHIKV infection and inflammation in vivo.

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https://api.crossref.org/works/10.1016%2FS1473-3099%2816%2930385-1

7 January 2021

Dephosphorylation of HuR protein during alphavirus infection is associated with HuR relocalization to the cytoplasm

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https://api.crossref.org/works/10.1016%2FS1473-3099%2816%2930385-1

7 January 2021

Sequestration of G3BP coupled with efficient translation inhibits stress granules in Semliki Forest virus infection

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https://api.crossref.org/works/10.1016%2FS1473-3099%2816%2930385-1

7 January 2021

Stress granule components G3BP1 and G3BP2 play a proviral role early in Chikungunya virus replication

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7 January 2021

Alphavirus RNA synthesis and non-structural protein functions

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https://api.crossref.org/works/10.1016%2FS1473-3099%2816%2930385-1

7 January 2021

Conservation of a packaging signal and the viral genome RNA packaging mechanism in alphavirus evolution

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7 January 2021

Characterization of synthetic Chikungunya viruses based on the consensus sequence of recent E1-226V isolates

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https://api.crossref.org/works/10.1016%2FS1473-3099%2816%2930385-1

7 January 2021

Chikungunya virus capsid protein contains nuclear import and export signals

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https://api.crossref.org/works/10.1016%2FS1473-3099%2816%2930385-1

7 January 2021

BST2/tetherin inhibition of alphavirus exit

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7 January 2021

BST-2/tetherin-mediated restriction of chikungunya (CHIKV) VLP budding is counteracted by CHIKV non-structural protein 1 (nsP1)

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7 January 2021

A polarized cell model for Chikungunya virus infection: entry and egress of virus occurs at the apical domain of polarized cells

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https://api.crossref.org/works/10.1016%2FS1473-3099%2816%2930385-1

7 January 2021

Seroprevalence of dengue, chikungunya and Sindbis virus infections in German aid workers

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7 January 2021

Seroprevalence and distribution of Flaviviridae, Togaviridae, and Bunyaviridae arboviral infections in rural Cameroonian adults.

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https://api.crossref.org/works/10.1016%2FS1473-3099%2816%2930385-1

7 January 2021

Chikungunya Virus, Cameroon, 2006

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https://api.crossref.org/works/10.1016%2FS1473-3099%2816%2930385-1

7 January 2021

Seroprevalence of five arboviruses in Zebu cattle in the Central African Republic

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https://api.crossref.org/works/10.1016%2FS1473-3099%2816%2930385-1

7 January 2021

Epidemic resurgence of Chikungunya virus in democratic Republic of the Congo: identification of a new central African strain

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7 January 2021

Circulation of Chikungunya virus in Gabon, 2006-2007.

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https://api.crossref.org/works/10.1016%2FS1473-3099%2816%2930385-1

7 January 2021

Acute arboviral infections in Guinea, West Africa, 2006.

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https://api.crossref.org/works/10.1016%2FS1473-3099%2816%2930385-1

7 January 2021

Seroprevalence of Chikungunya virus (CHIKV) infection on Lamu Island, Kenya, October 2004.

1 reference

https://api.crossref.org/works/10.1016%2FS1473-3099%2816%2930385-1

7 January 2021

An imported case of Chikungunya fever from Madagascar: use of the sentinel traveller for detecting emerging arboviral infections in tropical and European countries

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7 January 2021

Chikungunya fever as a risk factor for endemic Burkitt's lymphoma in Malawi

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https://api.crossref.org/works/10.1016%2FS1473-3099%2816%2930385-1

7 January 2021

Arthropod-borne viral infections of man in Nigeria, 1964–1970

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7 January 2021

The occurrence of Chikungunya virus in Uganda. I. Isolation from mosquitoes

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7 January 2021

Cluster of chikungunya virus infection in travelers returning from Senegal, 2006.

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https://api.crossref.org/works/10.1016%2FS1473-3099%2816%2930385-1

7 January 2021

Viral infections in travellers from tropical Africa

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7 January 2021

An outbreak of yellow fever with concurrent chikungunya virus transmission in South Kordofan, Sudan, 2005.

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https://api.crossref.org/works/10.1016%2FS1473-3099%2816%2930385-1

7 January 2021

Chikungunya fever outbreak, Bhutan, 2012

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https://api.crossref.org/works/10.1016%2FS1473-3099%2816%2930385-1

7 January 2021

Co-circulation of Dengue and Chikungunya Viruses, Al Hudaydah, Yemen, 2012.

1 reference

https://api.crossref.org/works/10.1016%2FS1473-3099%2816%2930385-1

7 January 2021

Re-emergence of Chikungunya and O'nyong-nyong viruses: evidence for distinct geographical lineages and distant evolutionary relationships

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7 January 2021

Genome microevolution of chikungunya viruses causing the Indian Ocean outbreak

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https://api.crossref.org/works/10.1016%2FS1473-3099%2816%2930385-1

7 January 2021

Tracking the re-emergence of epidemic chikungunya virus in Indonesia

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7 January 2021

Chikungunya, an epidemic arbovirosis

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7 January 2021

A226V strains of Chikungunya virus, Réunion Island, 2010.

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7 January 2021

Genetic divergence of Chikungunya viruses in India (1963-2006) with special reference to the 2005-2006 explosive epidemic

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https://api.crossref.org/works/10.1016%2FS1473-3099%2816%2930385-1

7 January 2021

Two Chikungunya isolates from the outbreak of La Reunion (Indian Ocean) exhibit different patterns of infection in the mosquito, Aedes albopictus

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7 January 2021

Sequential adaptive mutations enhance efficient vector switching by Chikungunya virus and its epidemic emergence

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https://api.crossref.org/works/10.1016%2FS1473-3099%2816%2930385-1

7 January 2021

Chikungunya virus emergence is constrained in Asia by lineage-specific adaptive landscapes

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https://api.crossref.org/works/10.1016%2FS1473-3099%2816%2930385-1

7 January 2021

Transcontinental movement of Asian genotype chikungunya virus

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7 January 2021

Emergence and potential for spread of Chikungunya virus in Brazil

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7 January 2021

Molecular Characterization of Chikungunya Virus, Philippines, 2011-2013

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7 January 2021

Beyond RNAi: antiviral defense strategies in Drosophila and mosquito

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7 January 2021

Characterization of Aedes aegypti innate-immune pathways that limit Chikungunya virus replication

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7 January 2021

New Insights into Control of Arbovirus Replication and Spread by Insect RNA Interference Pathways

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7 January 2021

Production of virus-derived ping-pong-dependent piRNA-like small RNAs in the mosquito soma

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7 January 2021

MicroRNAs: genomics, biogenesis, mechanism, and function

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7 January 2021

Next generation sequencing reveals regulation of distinct Aedes microRNAs during chikungunya virus development

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7 January 2021

Discovery of mosquito saliva microRNAs during CHIKV infection

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7 January 2021

Chikungunya viral arthritis in the United States: a mimic of seronegative rheumatoid arthritis

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7 January 2021

Chikungunya and the eye: a review

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7 January 2021

Epidemiology, clinical manifestations, and diagnosis of Chikungunya fever: lessons learned from the re-emerging epidemic

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7 January 2021

Chikungunya virus infection

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7 January 2021

Outbreak of chikungunya on Reunion Island: early clinical and laboratory features in 157 adult patients

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7 January 2021

Chikungunya infection in travelers

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7 January 2021

Morbidity and impaired quality of life 30 months after chikungunya infection: comparative cohort of infected and uninfected French military policemen in Reunion Island

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7 January 2021

Chikungunya virus-associated long-term arthralgia: a 36-month prospective longitudinal study

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7 January 2021

Atypical manifestations of chikungunya infection

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7 January 2021

Four cases of acute flaccid paralysis associated with chikungunya virus infection

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7 January 2021

Serious acute chikungunya virus infection requiring intensive care during the Reunion Island outbreak in 2005-2006.

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7 January 2021

Mother-to-child transmission of Chikungunya virus infection

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7 January 2021

Neurocognitive outcome of children exposed to perinatal mother-to-child Chikungunya virus infection: the CHIMERE cohort study on Reunion Island

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7 January 2021

A destructive arthropathy following Chikungunya virus arthritis--a possible association

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7 January 2021

Destructive arthritis in a patient with chikungunya virus infection with persistent specific IgM antibodies

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7 January 2021

Clinical progression of chikungunya fever during acute and chronic arthritic stages and the changes in joint morphology as revealed by imaging

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7 January 2021

Cytokine levels in patients with chikungunya virus infection

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7 January 2021

Inflammatory cytokine expression is associated with chikungunya virus resolution and symptom severity

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7 January 2021

Correlation of plasma viral loads and presence of Chikungunya IgM antibodies with cytokine/chemokine levels during acute Chikungunya virus infection

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7 January 2021

A Systematic Meta-analysis of Immune Signatures in Patients With Acute Chikungunya Virus Infection

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7 January 2021

A pathogenic role for CD4+ T cells during Chikungunya virus infection in mice

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https://api.crossref.org/works/10.1016%2FS1473-3099%2816%2930385-1

7 January 2021

A Rodent Model of Chikungunya Virus Infection in RAG1 -/- Mice, with Features of Persistence, for Vaccine Safety Evaluation

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7 January 2021

Longitudinal analysis of the human antibody response to Chikungunya virus infection: implications for serodiagnosis and vaccine development

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7 January 2021

Isolation and Characterization of Broad and Ultrapotent Human Monoclonal Antibodies with Therapeutic Activity against Chikungunya Virus

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7 January 2021

Interleukin 6, RANKL, and osteoprotegerin expression by chikungunya virus-infected human osteoblasts

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7 January 2021

Chikungunya disease in nonhuman primates involves long-term viral persistence in macrophages

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https://api.crossref.org/works/10.1016%2FS1473-3099%2816%2930385-1

7 January 2021

Comparative pathogenesis of epidemic and enzootic Chikungunya viruses in a pregnant Rhesus macaque model

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7 January 2021

Chikungunya virus infection results in higher and persistent viral replication in aged rhesus macaques due to defects in anti-viral immunity

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7 January 2021

Loss of TLR3 aggravates CHIKV replication and pathology due to an altered virus-specific neutralizing antibody response

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7 January 2021

Bindarit, an inhibitor of monocyte chemotactic protein synthesis, protects against bone loss induced by chikungunya virus infection

1 reference

https://api.crossref.org/works/10.1016%2FS1473-3099%2816%2930385-1

7 January 2021

CCR2 deficiency promotes exacerbated chronic erosive neutrophil-dominated chikungunya virus arthritis

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https://api.crossref.org/works/10.1016%2FS1473-3099%2816%2930385-1

7 January 2021

Interferon response factors 3 and 7 protect against Chikungunya virus hemorrhagic fever and shock

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https://api.crossref.org/works/10.1016%2FS1473-3099%2816%2930385-1

7 January 2021

Chikungunya virus induces IPS-1-dependent innate immune activation and protein kinase R-independent translational shutoff

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7 January 2021

Gene profiling of Chikungunya virus arthritis in a mouse model reveals significant overlap with rheumatoid arthritis

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https://api.crossref.org/works/10.1016%2FS1473-3099%2816%2930385-1

7 January 2021

Chronic joint disease caused by persistent Chikungunya virus infection is controlled by the adaptive immune response

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7 January 2021

Antiviral treatment of chikungunya virus infection

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7 January 2021

In vitro inhibition of Chikungunya and Semliki Forest viruses replication by antiviral compounds: synergistic effect of interferon-alpha and ribavirin combination

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https://api.crossref.org/works/10.1016%2FS1473-3099%2816%2930385-1

7 January 2021

Cellular IMPDH enzyme activity is a potential target for the inhibition of Chikungunya virus replication and virus induced apoptosis in cultured mammalian cells

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7 January 2021

Chikungunya virus: an update on antiviral development and challenges

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7 January 2021

Mutations in the chikungunya virus non-structural proteins cause resistance to favipiravir (T-705), a broad-spectrum antiviral

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7 January 2021

Computer-aided identification, design and synthesis of a novel series of compounds with selective antiviral activity against chikungunya virus

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7 January 2021

Antiviral chlorinated daphnane diterpenoid orthoesters from the bark and wood of Trigonostemon cherrieri

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https://api.crossref.org/works/10.1016%2FS1473-3099%2816%2930385-1

7 January 2021

Prostratin and 12-O-tetradecanoylphorbol 13-acetate are potent and selective inhibitors of Chikungunya virus replication

1 reference

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7 January 2021

Betulin-derived compounds as inhibitors of alphavirus replication

1 reference

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7 January 2021

Identification of novel compounds inhibiting chikungunya virus-induced cell death by high throughput screening of a kinase inhibitor library

1 reference

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7 January 2021

Development of an attenuated strain of chikungunya virus for use in vaccine production

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7 January 2021

US Military contributions to the global response to pandemic chikungunya

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7 January 2021

Deciphering the protective role of adaptive immunity to CHIKV/IRES a novel candidate vaccine against Chikungunya in the A129 mouse model

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7 January 2021

Novel chikungunya vaccine candidate with an IRES-based attenuation and host range alteration mechanism

1 reference

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7 January 2021

Cross-protective immunity against o'nyong-nyong virus afforded by a novel recombinant chikungunya vaccine

1 reference

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7 January 2021

Chikungunya vaccine candidate is highly attenuated and protects nonhuman primates against telemetrically monitored disease following a single dose.

1 reference

https://api.crossref.org/works/10.1016%2FS1473-3099%2816%2930385-1

7 January 2021

Novel attenuated Chikungunya vaccine candidates elicit protective immunity in C57BL/6 mice

1 reference

https://api.crossref.org/works/10.1016%2FS1473-3099%2816%2930385-1

7 January 2021

A virus-like particle vaccine for epidemic Chikungunya virus protects nonhuman primates against infection

1 reference

https://api.crossref.org/works/10.1016%2FS1473-3099%2816%2930385-1

7 January 2021

Arbovirus vaccines; opportunities for the baculovirus-insect cell expression system

1 reference

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7 January 2021

Chikungunya virus-like particles are more immunogenic in a lethal AG129 mouse model compared to glycoprotein E1 or E2 subunits

1 reference

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7 January 2021

A specific domain of the Chikungunya virus E2 protein regulates particle formation in human cells: implications for alphavirus vaccine design

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7 January 2021

A recombinant measles vaccine expressing chikungunya virus-like particles is strongly immunogenic and protects mice from lethal challenge with chikungunya virus

1 reference

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7 January 2021

Safety and tolerability of chikungunya virus-like particle vaccine in healthy adults: a phase 1 dose-escalation trial

1 reference

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7 January 2021

Immunogenicity, safety, and tolerability of a recombinant measles-virus-based chikungunya vaccine: a randomised, double-blind, placebo-controlled, active-comparator, first-in-man trial

1 reference

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7 January 2021

A complex adenovirus vaccine against chikungunya virus provides complete protection against viraemia and arthritis

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7 January 2021

A chimeric vesiculo/alphavirus is an effective alphavirus vaccine

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7 January 2021

A novel poxvirus-based vaccine, MVA-CHIKV, is highly immunogenic and protects mice against chikungunya infection.

1 reference

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7 January 2021

Immunogenicity of novel consensus-based DNA vaccines against Chikungunya virus

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7 January 2021

A DNA vaccine against chikungunya virus is protective in mice and induces neutralizing antibodies in mice and nonhuman primates

1 reference

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7 January 2021

Nonstructural protein 2 (nsP2) of Chikungunya virus (CHIKV) enhances protective immunity mediated by a CHIKV envelope protein expressing DNA Vaccine

1 reference

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7 January 2021

Subunit vaccine formulations based on recombinant envelope proteins of Chikungunya virus elicit balanced Th1/Th2 response and virus-neutralizing antibodies in mice

1 reference

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7 January 2021

Evaluation of recombinant E2 protein-based and whole-virus inactivated candidate vaccines against chikungunya virus

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7 January 2021

Prophylaxis and therapy for Chikungunya virus infection

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7 January 2021

Use of human monoclonal antibodies to treat Chikungunya virus infection

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7 January 2021

A neutralizing monoclonal antibody targeting the acid-sensitive region in chikungunya virus E2 protects from disease

1 reference

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7 January 2021

Broadly Neutralizing Alphavirus Antibodies Bind an Epitope on E2 and Inhibit Entry and Egress

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7 January 2021

10.1016/S1473-3099(16)30385-1

Identifiers

DOI

1 reference

12 June 2017

1 reference

PubMed ID

28159534