Interfacial water molecules in SH3 interactions: Getting the full picture on polyproline recognition by protein-protein interaction domains (Q30010103)

21 May 2017

title

Interfacial water molecules in SH3 interactions: Getting the full picture on polyproline recognition by protein-protein interaction domains (English)

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protein-protein interaction

21 May 2017

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2

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Ana Zafra-Ruano

series ordinal

1

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language of work or name

English

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publication date

11 May 2012

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21 May 2017

number of pages

12

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based on heuristic

inferred from page(s)

published in

FEBS Letters

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21 May 2017

volume

586

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21 May 2017

issue

17

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21 May 2017

page(s)

2619-2630

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Interaction domains: from simple binding events to complex cellular behavior

21 May 2017

cites work

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2012.04.057

Signaling through scaffold, anchoring, and adaptor proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2012.04.057

The identification of short linear motif-mediated interfaces within the human interactome

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2012.04.057

ELM: the status of the 2010 eukaryotic linear motif resource

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2012.04.057

MOTIPS: automated motif analysis for predicting targets of modular protein domains

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2012.04.057

Comparative genomics of the eukaryotes

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2012.04.057

Distribution of proline-rich (PxxP) motifs in distinct proteomes: functional and therapeutic implications for malaria and tuberculosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2012.04.057

The effect of the polyproline II (PPII) conformation on the denatured state entropy.

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2012.04.057

A survey of left-handed polyproline II helices

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2012.04.057

Selectivity and promiscuity in the interaction network mediated by protein recognition modules

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2012.04.057

Recognition of proline-rich motifs by protein-protein-interaction domains

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2012.04.057

Specificity and versatility of SH3 and other proline-recognition domains: structural basis and implications for cellular signal transduction

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2012.04.057

Proline-rich sequence recognition domains (PRD): ligands, function and inhibition

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2012.04.057

The SH3 domain--a family of versatile peptide- and protein-recognition module

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2012.04.057

Searching for specificity in SH domains

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2012.04.057

Evolving specificity from variability for protein interaction domains

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2012.04.057

In vitro evolution of recognition specificity mediated by SH3 domains reveals target recognition rules

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2012.04.057

Energetics of Src homology domain interactions in receptor tyrosine kinase-mediated signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2012.04.057

UCS15A, a novel small molecule, SH3 domain-mediated protein-protein interaction blocking drug

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2012.04.057

Identification of preferred protein interactions by phage-display of the human Src homology-3 proteome

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2012.04.057

WW and SH3 domains, two different scaffolds to recognize proline-rich ligands

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2012.04.057

The role of the Src homology 3-Src homology 2 interface in the regulation of Src kinases

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2012.04.057

An intramolecular SH3-domain interaction regulates c-Abl activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2012.04.057

Critical amino acid substitutions in the Src SH3 domain that convert c-Src to be oncogenic

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2012.04.057

Fyn kinase induces synaptic and cognitive impairments in a transgenic mouse model of Alzheimer's disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2012.04.057

Thermodynamic and kinetic analysis of the SH3 domain of spectrin shows a two-state folding transition.

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2012.04.057

A thermodynamic and kinetic analysis of the folding pathway of an SH3 domain entropically stabilised by a redesigned hydrophobic core

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2012.04.057

The folding transition state between SH3 domains is conformationally restricted and evolutionarily conserved.

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2012.04.057

Obligatory steps in protein folding and the conformational diversity of the transition state

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2012.04.057

Experiment and theory highlight role of native state topology in SH3 folding

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2012.04.057

Conformational analysis of peptides corresponding to beta-hairpins and a beta-sheet that represent the entire sequence of the alpha-spectrin SH3 domain.

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2012.04.057

The native state conformational ensemble of the SH3 domain from alpha-spectrin

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2012.04.057

Solution structure, dynamics, and thermodynamics of the native state ensemble of the Sem-5 C-terminal SH3 domain

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2012.04.057

Cooperative propagation of local stability changes from low-stability and high-stability regions in a SH3 domain

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2012.04.057

Characterizing the role of ensemble modulation in mutation-induced changes in binding affinity

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2012.04.057

Exploiting the basis of proline recognition by SH3 and WW domains: design of N-substituted inhibitors

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2012.04.057

Specific interactions outside the proline-rich core of two classes of Src homology 3 ligands

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2012.04.057

Systematic identification of SH3 domain-mediated human protein-protein interactions by peptide array target screening

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2012.04.057

Versatile retargeting of SH3 domain binding by modification of non-conserved loop residues

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2012.04.057

RT loop flexibility enhances the specificity of Src family SH3 domains for HIV-1 Nef

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2012.04.057

The SH3 domain of Eps8 exists as a novel intertwined dimer

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2012.04.057

A novel peptide-SH3 interaction.

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2012.04.057

Specific oncogenic activity of the Src-family tyrosine kinase c-Yes in colon carcinoma cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2012.04.057

Specificity in signaling by c-Yes

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2012.04.057

Two binding orientations for peptides to the Src SH3 domain: development of a general model for SH3-ligand interactions

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2012.04.057

Structural determinants of peptide-binding orientation and of sequence specificity in SH3 domains

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2012.04.057

The tryptophan switch: changing ligand-binding specificity from type I to type II in SH3 domains

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2012.04.057

Normalization of nomenclature for peptide motifs as ligands of modular protein domains

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2012.04.057

A novel, specific interaction involving the Csk SH3 domain and its natural ligand

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2012.04.057

Diverse recognition of non-PxxP peptide ligands by the SH3 domains from p67(phox), Grb2 and Pex13p

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2012.04.057

Mona/Gads SH3C binding to hematopoietic progenitor kinase 1 (HPK1) combines an atypical SH3 binding motif, R/KXXK, with a classical PXXP motif embedded in a polyproline type II (PPII) helix

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2012.04.057

Atypical polyproline recognition by the CMS N-terminal Src homology 3 domain

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2012.04.057

A noncanonical SH3 domain binding motif links BK channels to the actin cytoskeleton via the SH3 adapter cortactin

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2012.04.057

Structural basis for specific binding of the Gads SH3 domain to an RxxK motif-containing SLP-76 peptide: a novel mode of peptide recognition

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2012.04.057

Efficient T-cell receptor signaling requires a high-affinity interaction between the Gads C-SH3 domain and the SLP-76 RxxK motif

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2012.04.057

SH2 and SH3 domains as targets for anti-proliferative agents

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2012.04.057

SH2 and SH3 domains: potential targets for anti-cancer drug design

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2012.04.057

Inhibitors of Ras signal transduction as antitumor agents

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2012.04.057

Nef surfaces: where to interfere with function

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2012.04.057

Acquisition of Fyn-selective SH3 domain ligands via a combinatorial library strategy

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2012.04.057

Synthetic inhibitors of proline-rich ligand-mediated protein-protein interaction: potent analogs of UCS15A.

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2012.04.057

A combined experimental and computational strategy to define protein interaction networks for peptide recognition modules

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2012.04.057

A miniprotein scaffold used to assemble the polyproline II binding epitope recognized by SH3 domains.

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2012.04.057

Rational design of specific high-affinity peptide ligands for the Abl-SH3 domain

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2012.04.057

Molecular modeling of the interaction of polyproline-based peptides with the Abl-SH3 domain: rational modification of the interaction

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2012.04.057

21 January 2018

Drugging the undruggable

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2012.04.057

Design of peptoid analogue dimers and measure of their affinity for Grb2 SH3 domains.

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2012.04.057

Synthesis of 5-, 6- and 7-substituted-2-aminoquinolines as SH3 domain ligands

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2012.04.057

Identification and specificity studies of small-molecule ligands for SH3 protein domains

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2012.04.057

Improving SH3 domain ligand selectivity using a non-natural scaffold

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2012.04.057

Ligand recognition by SH3 and WW domains: the role of N-alkylation in PPII helices

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2012.04.057

A thermodynamic approach to the affinity optimization of drug candidates

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2012.04.057

Do enthalpy and entropy distinguish first in class from best in class?

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2012.04.057

Compensating enthalpic and entropic changes hinder binding affinity optimization

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2012.04.057

ITC in the post-genomic era...? Priceless

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2012.04.057

Thermodynamics-based drug design: strategies for inhibiting protein-protein interactions

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2012.04.057

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2012.04.057

Adding calorimetric data to decision making in lead discovery: a hot tip

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2012.04.057

Finding a better path to drug selectivity

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2012.04.057

Calorimetry and thermodynamics in drug design

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2012.04.057

Measurements of binding thermodynamics in drug discovery

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2012.04.057

Overcoming drug resistance in HIV-1 chemotherapy: the binding thermodynamics of Amprenavir and TMC-126 to wild-type and drug-resistant mutants of the HIV-1 protease

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2012.04.057

Thermodynamics of binding to SH3 domains: the energetic impact of polyproline II (PII) helix formation

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2012.04.057

Thermodynamic dissection of the binding energetics of proline-rich peptides to the Abl-SH3 domain: implications for rational ligand design

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2012.04.057

Structural and thermodynamic characterization of the interaction of the SH3 domain from Fyn with the proline-rich binding site on the p85 subunit of PI3-kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2012.04.057

The role of backbone motions in ligand binding to the c-Src SH3 domain

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2012.04.057

Orientation of peptide fragments from Sos proteins bound to the N-terminal SH3 domain of Grb2 determined by NMR spectroscopy

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2012.04.057

Recognition of lysine-rich peptide ligands by murine cortactin SH3 domain: CD, ITC, and NMR studies

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2012.04.057

Dynamic Nef and Nef dynamics: how structure could explain the complex activities of this small HIV protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2012.04.057

SAP couples Fyn to SLAM immune receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2012.04.057

Structural basis of PxxDY motif recognition in SH3 binding

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2012.04.057

SH3 domains of Grb2 adaptor bind to PXpsiPXR motifs within the Sos1 nucleotide exchange factor in a discriminate manner

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2012.04.057

Ligand-induced changes in dynamics in the RT loop of the C-terminal SH3 domain of Sem-5 indicate cooperative conformational coupling

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2012.04.057

Ligand-induced strain in hydrogen bonds of the c-Src SH3 domain detected by NMR.

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2012.04.057

Mutational analysis of the regulatory function of the c-Abl Src homology 3 domain

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2012.04.057

Mechanisms of autoinhibition and STI-571/imatinib resistance revealed by mutagenesis of BCR-ABL.

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2012.04.057

Characterization of the interaction of natural proline-rich peptides with five different SH3 domains.

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2012.04.057

Crystal structure of the abl-SH3 domain complexed with a designed high-affinity peptide ligand: implications for SH3-ligand interactions

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2012.04.057

Structural parameterization of the binding enthalpy of small ligands

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2012.04.057

Thermodynamic dissection of the binding energetics of KNI-272, a potent HIV-1 protease inhibitor

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2012.04.057

Role of Interfacial Water Molecules in Proline-rich Ligand Recognition by the Src Homology 3 Domain of Abl

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2012.04.057

Interfacial water molecules in SH3 interactions: a revised paradigm for polyproline recognition.

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2012.04.057

Docking of hydrophobic ligands with interaction-based matching algorithms.

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2012.04.057

Molecular docking with ligand attached water molecules.

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2012.04.057

Ligand-protein cross-docking with water molecules

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2012.04.057

Solvated docking: introducing water into the modelling of biomolecular complexes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2012.04.057

Modeling water molecules in protein-ligand docking using GOLD.

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2012.04.057

De novo ligand design with explicit water molecules: an application to bacterial neuraminidase.

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2012.04.057

The effect of a tightly bound water molecule on scaffold diversity in the computer-aided de novo ligand design of CDK2 inhibitors.

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2012.04.057

Including tightly-bound water molecules in de novo drug design. Exemplification through the in silico generation of poly(ADP-ribose)polymerase ligands.

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2012.04.057

The role of water molecules in computational drug design

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2012.04.057

Win some, lose some: enthalpy-entropy compensation in weak intermolecular interactions

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2012.04.057

The Entropic Cost of Bound Water in Crystals and Biomolecules

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2012.04.057

The role of water in sequence-independent ligand binding by an oligopeptide transporter protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2012.04.057

Just add water! The effect of water on the specificity of protein-ligand binding sites and its potential application to drug design

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2012.04.057

Thermodynamics of buried water clusters at a protein-ligand binding interface

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2012.04.057

Thermodynamic consequences of disrupting a water-mediated hydrogen bond network in a protein:pheromone complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2012.04.057

Rational design of potent, bioavailable, nonpeptide cyclic ureas as HIV protease inhibitors

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2012.04.057

Structure-based design of potent inhibitors of scytalone dehydratase: displacement of a water molecule from the active site

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2012.04.057

Crystallographic and calorimetric analysis of peptide binding to OppA protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2012.04.057

Enthalpy of hydrogen bond formation in a protein-ligand binding reaction

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2012.04.057

Involvement of water in carbohydrate-protein binding.

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2012.04.057

Predicting conserved water-mediated and polar ligand interactions in proteins using a K-nearest-neighbors genetic algorithm.

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2012.04.057

WaterScore: a novel method for distinguishing between bound and displaceable water molecules in the crystal structure of the binding site of protein-ligand complexes

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2012.04.057

HINT: a new method of empirical hydrophobic field calculation for CoMFA.

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2012.04.057

A computational tool to optimize ligand selectivity between two similar biomacromolecular targets

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2012.04.057

A computational procedure for determining energetically favorable binding sites on biologically important macromolecules

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2012.04.057

The statistical-thermodynamic basis for computation of binding affinities: a critical review

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2012.04.057

Standard free energy of releasing a localized water molecule from the binding pockets of proteins: double-decoupling method.

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2012.04.057

Inhibitors to the Src SH2 domain: a lesson in structure--thermodynamic correlation in drug design.

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2012.04.057

The structural basis of sequence-independent peptide binding by OppA protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2012.04.057

Hydration dynamics of the collagen triple helix by NMR.

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2012.04.057

The application of thermodynamic methods in drug design

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2012.04.057

10.1016/J.FEBSLET.2012.04.057

21 January 2018

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DOI

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21 May 2017

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