Autophosphorylation and ATM activation: additional sites add to the complexity (Q30498797)

19 October 2017

Autophosphorylation and ATM activation: additional sites add to the complexity (English)

1 reference

19 October 2017

8

1 reference

19 October 2017

Mark E Graham

2

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Burkhard Jakob

object named as

Burkhard Jakob

3

0 references

Gisela Taucher-Scholz

9

object named as

Gisela Taucher-Scholz

1 reference

19 October 2017

4

Frank Tobias

1 reference

19 October 2017

5

Amanda W Kijas

1 reference

19 October 2017

13

Martin F Lavin

1 reference

19 October 2017

Sergei V Kozlov

1

1 reference

19 October 2017

Marcel Tanuji

6

1 reference

19 October 2017

Philip Chen

7

1 reference

19 October 2017

Keiji Suzuki

10

1 reference

19 October 2017

Sairai So

11

1 reference

19 October 2017

David Chen

12

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19 October 2017

language of work or name

English

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publication date

13 December 2010

1 reference

Journal of Biological Chemistry

19 October 2017

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19 October 2017

286

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19 October 2017

11

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19 October 2017

9107-9119

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ATM-dependent and -independent dynamics of the nuclear phosphoproteome after DNA damage

19 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3059052

ATM activation by oxidative stress

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3059052

Autophosphorylation at serine 1981 stabilizes ATM at DNA damage sites

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3059052

Histone H3 methylation links DNA damage detection to activation of the tumour suppressor Tip60.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3059052

Role of mammalian Mre11 in classical and alternative nonhomologous end joining

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3059052

Role of Mre11 in chromosomal nonhomologous end joining in mammalian cells

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3059052

Common mechanisms of PIKK regulation

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3059052

Human RAD50 deficiency in a Nijmegen breakage syndrome-like disorder

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3059052

Solving the RIDDLE of 53BP1 recruitment to sites of damage

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3059052

Crosstalk between histone modifications during the DNA damage response.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3059052

Tyrosine dephosphorylation of H2AX modulates apoptosis and survival decisions

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3059052

MRN complex function in the repair of chromosomal Rag-mediated DNA double-strand breaks

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3059052

RNF168 binds and amplifies ubiquitin conjugates on damaged chromosomes to allow accumulation of repair proteins

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3059052

Phosphorylation of ATM by Cdk5 mediates DNA damage signalling and regulates neuronal death

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3059052

Multiple autophosphorylation sites are dispensable for murine ATM activation in vivo

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3059052

Ataxia-telangiectasia: from a rare disorder to a paradigm for cell signalling and cancer

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3059052

Activation of ATR and related PIKKs

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3059052

Phospho-dependent interactions between NBS1 and MDC1 mediate chromatin retention of the MRN complex at sites of DNA damage

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3059052

Activation of the cellular DNA damage response in the absence of DNA lesions

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3059052

Phosphorylation of SDT repeats in the MDC1 N terminus triggers retention of NBS1 at the DNA damage-modified chromatin

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3059052

Regulation of DNA double-strand break repair pathway choice

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3059052

Orchestration of the DNA-damage response by the RNF8 ubiquitin ligase

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3059052

RNF8 transduces the DNA-damage signal via histone ubiquitylation and checkpoint protein assembly

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3059052

RNF8 ubiquitylates histones at DNA double-strand breaks and promotes assembly of repair proteins

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3059052

Rapid activation of ATM on DNA flanking double-strand breaks

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3059052

DNA damage-induced acetylation of lysine 3016 of ATM activates ATM kinase activity

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3059052

DNA strand break repair and human genetic disease

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3059052

ATM and ATR substrate analysis reveals extensive protein networks responsive to DNA damage

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3059052

Roles of ATM and NBS1 in chromatin structure modulation and DNA double-strand break repair

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3059052

Function of the ATR N-terminal domain revealed by an ATM/ATR chimera

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3059052

The ATM-dependent DNA damage signaling pathway

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3059052

Involvement of novel autophosphorylation sites in ATM activation

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3059052

ATM stabilizes DNA double-strand-break complexes during V(D)J recombination.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3059052

Imaging of protein movement induced by chromosomal breakage: tiny 'local' lesions pose great 'global' challenges

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3059052

Identification of domains of ataxia-telangiectasia mutated required for nuclear localization and chromatin association.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3059052

ATM activation by DNA double-strand breaks through the Mre11-Rad50-Nbs1 complex

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3059052

Conserved modes of recruitment of ATM, ATR and DNA-PKcs to sites of DNA damage

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3059052

DNA damage-induced association of ATM with its target proteins requires a protein interaction domain in the N terminus of ATM.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3059052

Large-scale characterization of HeLa cell nuclear phosphoproteins

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3059052

The Mre11 complex and the metabolism of chromosome breaks: the importance of communicating and holding things together

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3059052

Independent roles for nibrin and Mre11-Rad50 in the activation and function of Atm.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3059052

Mdc1 couples DNA double-strand break recognition by Nbs1 with its H2AX-dependent chromatin retention

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3059052

Phosphorylation of SMC1 is a critical downstream event in the ATM-NBS1-BRCA1 pathway

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3059052

Direct activation of the ATM protein kinase by the Mre11/Rad50/Nbs1 complex

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3059052

Stable-isotope dimethyl labeling for quantitative proteomics

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3059052

Requirement of the MRN complex for ATM activation by DNA damage

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3059052

ATP activates ataxia-telangiectasia mutated (ATM) in vitro. Importance of autophosphorylation

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3059052

Distinct spatiotemporal dynamics of mammalian checkpoint regulators induced by DNA damage

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3059052

DNA damage activates ATM through intermolecular autophosphorylation and dimer dissociation

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3059052

An ATR- and Chk1-dependent S checkpoint inhibits replicon initiation following UVC-induced DNA damage

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3059052

Functional link between BLM defective in Bloom's syndrome and the ataxia-telangiectasia-mutated protein, ATM

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3059052

Characterization of ataxia telangiectasia fibroblasts with extended life-span through telomerase expression.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3059052

A critical role for histone H2AX in recruitment of repair factors to nuclear foci after DNA damage

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3059052

The DNA double-strand break repair gene hMRE11 is mutated in individuals with an ataxia-telangiectasia-like disorder

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3059052

Requirement of ATM-dependent phosphorylation of brca1 in the DNA damage response to double-strand breaks

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3059052

ATM associates with and phosphorylates p53: mapping the region of interaction

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3059052

The hMre11/hRad50 protein complex and Nijmegen breakage syndrome: linkage of double-strand break repair to the cellular DNA damage response

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3059052

hMre11 and hRad50 nuclear foci are induced during the normal cellular response to DNA double-strand breaks

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3059052

Isolation of full-length ATM cDNA and correction of the ataxia-telangiectasia cellular phenotype

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3059052

The genetic defect in ataxia-telangiectasia

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3059052

Genomic organization of the ATM locus involved in ataxia-telangiectasia.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3059052

A single ataxia telangiectasia gene with a product similar to PI-3 kinase

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3059052

Two-step activation of ATM by DNA and the Mre11-Rad50-Nbs1 complex.

20 June 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.204065

Differential phosphorylation of dynamin I isoforms in subcellular compartments demonstrates the hidden complexity of phosphoproteomes

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.204065

Comparative phosphoproteomics of zebrafish Fyn/Yes morpholino knockdown embryos

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.204065

Live cell imaging of heavy-ion-induced radiation responses by beamline microscopy.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.204065

Kinase-selective enrichment enables quantitative phosphoproteomics of the kinome across the cell cycle

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.204065

Biological imaging of heavy charged-particle tracks

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.204065

Effect of ionizing radiation on synthesis of sub-replicon size DNA in ataxia telangiectasia cells.

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3059052

Autophosphorylation at serine 1987 is dispensable for murine Atm activation in vivo

26 November 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.204065

Autophosphorylation at serine 1987 is dispensable for murine Atm activation in vivo

21 January 2018

1 reference

12 December 2020

Immediate localized CDKN1A (p21) radiation response after damage produced by heavy-ion tracks

1 reference

12 December 2020

DNA double labelling with IdUrd and CldUrd for spatial and temporal analysis of cell proliferation and DNA replication

1 reference

12 December 2020

High resolution visual mapping of stretched DNA by fluorescent hybridization

1 reference

12 December 2020

Identifiers

DOI

10.1074/JBC.M110.204065

1 reference

19 October 2017

1 reference

19 October 2017

1 reference