Hes1 potentiates T cell lymphomagenesis by up-regulating a subset of notch target genes (Q33494549)

27 July 2017

title

Hes1 potentiates T cell lymphomagenesis by up-regulating a subset of notch target genes (English)

1 reference

27 July 2017

Darryll D Dudley

1

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27 July 2017

Hong-Cheng Wang

series ordinal

2

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27 July 2017

Xiao-Hong Sun

series ordinal

3

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27 July 2017

language of work or name

English

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publication date

18 August 2009

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27 July 2017

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27 July 2017

volume

4

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27 July 2017

issue

8

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27 July 2017

page(s)

e6678

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Creative Commons Attribution 4.0 International

27 July 2017

copyright license

start time

18 August 2009

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

0 references

cites work

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Launching the T-cell-lineage developmental programme

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NOTCH1 directly regulates c-MYC and activates a feed-forward-loop transcriptional network promoting leukemic cell growth

21 June 2018

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c-Myc is an important direct target of Notch1 in T-cell acute lymphoblastic leukemia/lymphoma

21 June 2018

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Notch1 promotes survival of E2A-deficient T cell lymphomas through pre-T cell receptor-dependent and -independent mechanisms.

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Notch activation is an early and critical event during T-Cell leukemogenesis in Ikaros-deficient mice

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Regulation of lymphoid development, differentiation, and function by the Notch pathway.

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Activating mutations of NOTCH1 in human T cell acute lymphoblastic leukemia

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Hyperresponse to T-cell receptor signaling and apoptosis of Id1 transgenic thymocytes

21 June 2018

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TAL1/SCL induces leukemia by inhibiting the transcriptional activity of E47/HEB.

21 June 2018

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Notch-induced E2A ubiquitination and degradation are controlled by MAP kinase activities

21 June 2018

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Pre-TCR-triggered ERK signalling-dependent downregulation of E2A activity in Notch3-induced T-cell lymphoma

21 June 2018

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Regulation of thymocyte differentiation: pre-TCR signals and beta-selection

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Gene expression signatures define novel oncogenic pathways in T cell acute lymphoblastic leukemia

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Overexpression of the Notch target genes Hes in vivo induces lymphoid and myeloid alterations

21 June 2018

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The Nrarp gene encodes an ankyrin-repeat protein that is transcriptionally regulated by the notch signaling pathway

21 June 2018

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Role for Hes1-induced phosphorylation in Groucho-mediated transcriptional repression

21 June 2018

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Notch signaling in leukemia

21 June 2018

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Early thymocyte development is regulated by modulation of E2A protein activity

21 June 2018

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The DNA binding activity of TAL-1 is not required to induce leukemia/lymphoma in mice

21 June 2018

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Branching out to gain control: how the pre-TCR is linked to multiple functions

21 June 2018

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Constitutive activation of NF-kappaB and T-cell leukemia/lymphoma in Notch3 transgenic mice

21 June 2018

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Massive apoptosis of thymocytes in T-cell-deficient Id1 transgenic mice

21 June 2018

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Overexpression of the Helix-Loop-Helix protein Id2 blocks T cell development at multiple stages.

21 June 2018

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The bHLH gene Hes1 is essential for expansion of early T cell precursors

21 June 2018

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Notch-1 signalling requires ligand-induced proteolytic release of intracellular domain

21 June 2018

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High incidence of T-cell tumors in E2A-null mice and E2A/Id1 double-knockout mice

21 June 2018

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Exclusive development of T cell neoplasms in mice transplanted with bone marrow expressing activated Notch alleles

21 June 2018

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Positive selection of lymphocytes

21 June 2018

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TAL1, TAL2 and LYL1: a family of basic helix-loop-helix proteins implicated in T cell acute leukaemia

21 June 2018

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Groucho is required for Drosophila neurogenesis, segmentation, and sex determination and interacts directly with hairy-related bHLH proteins

21 June 2018

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21 June 2018

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Signalling downstream of activated mammalian Notch

21 June 2018

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Involvement of c-myc in MuLV-induced T cell lymphomas in mice: frequency and mechanisms of activation

21 June 2018

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Breakpoints in the human T-cell antigen receptor alpha-chain locus in two T-cell leukaemia patients with chromosomal translocations.

21 June 2018

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An intermediate cell in thymocyte differentiation that expresses CD8 but not CD4 antigen

21 June 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2722736

The tal gene undergoes chromosome translocation in T cell leukemia and potentially encodes a helix-loop-helix protein

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2722736

Disruption of thymocyte development and lymphomagenesis induced by SV40 T-antigen

21 June 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2722736

TAN-1, the human homolog of the Drosophila Notch gene, is broken by chromosomal translocations in T lymphoblastic neoplasms

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2722736

Molecular characterization of a rat negative regulator with a basic helix-loop-helix structure predominantly expressed in the developing nervous system

21 June 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2722736

Two mammalian helix-loop-helix factors structurally related to Drosophila hairy and Enhancer of split

21 June 2018

1 reference

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The earliest subpopulation of mouse thymocytes contains potent T, significant macrophage, and natural killer cell but no B-lymphocyte potential.

21 June 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0006678

Notch signaling controls the generation and differentiation of early T lineage progenitors

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0006678

Deficient T cell fate specification in mice with an induced inactivation of Notch1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0006678

Notch1 expression in early lymphopoiesis influences B versus T lineage determination

21 January 2018

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https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0006678

Notch signaling is involved in the regulation of Id3 gene transcription during Xenopus embryogenesis.

21 January 2018

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https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0006678

An analysis of T cell intrinsic roles of E2A by conditional gene disruption in the thymus.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0006678

Differentiation potential of 14-day fetal mouse thymocytes in organ culture. Analysis of CD4/CD8-defined single-positive and double-negative cells

21 January 2018

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12 December 2020

Expression and purification of a soluble tissue factor fusion protein with an epitope for an unusual calcium-dependent antibody

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12 December 2020

Identification of Notch target genes in uncommitted T-cell progenitors: No direct induction of a T-cell specific gene program

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12 December 2020

Helix-loop-helix proteins regulate pre-TCR and TCR signaling through modulation of Rel/NF-kappaB activities

1 reference

12 December 2020

A reassessment of the effect of activated Notch1 on CD4 and CD8 T cell development

1 reference

12 December 2020

10.1371/JOURNAL.PONE.0006678

Identifiers

DOI

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27 July 2017

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27 July 2017

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