Cathepsin L inhibition prevents murine autoimmune diabetes via suppression of CD8(+) T cell activity (Q33705115)

28 July 2017

Cathepsin L inhibition prevents murine autoimmune diabetes via suppression of CD8(+) T cell activity (English)

1 reference

28 July 2017

Akiko Yamada

1

1 reference

28 July 2017

Naozumi Ishimaru

2

1 reference

28 July 2017

Rieko Arakaki

3

1 reference

28 July 2017

Nobuhiko Katunuma

4

1 reference

28 July 2017

Yoshio Hayashi

5

1 reference

28 July 2017

language of work or name

English

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publication date

22 September 2010

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28 July 2017

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28 July 2017

5

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28 July 2017

9

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28 July 2017

e12894

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Creative Commons Attribution 4.0 International

28 July 2017

start time

22 September 2010

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

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cites work

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Cytokine and cytokine-like inflammation markers, endothelial dysfunction, and imbalanced coagulation in development of diabetes and its complications

21 June 2018

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Cathepsin K-dependent toll-like receptor 9 signaling revealed in experimental arthritis.

21 June 2018

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Cathepsin L activity controls adipogenesis and glucose tolerance

21 June 2018

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Translational mini-review series on type 1 diabetes: Systematic analysis of T cell epitopes in autoimmune diabetes

21 June 2018

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21 June 2018

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Cysteine cathepsins: multifunctional enzymes in cancer

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Foxp3+ CD25+ CD4+ natural regulatory T cells in dominant self-tolerance and autoimmune disease

21 June 2018

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Where CD4+CD25+ T reg cells impinge on autoimmune diabetes

21 June 2018

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Cathepsin L is essential for onset of autoimmune diabetes in NOD mice

21 June 2018

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The relationship between immunodominance, DM editing, and the kinetic stability of MHC class II:peptide complexes

21 June 2018

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The lysosomal cysteine proteases in MHC class II antigen presentation

21 June 2018

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The good turned ugly: immunopathogenic basis for diabetogenic CD8+ T cells in NOD mice

21 June 2018

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Naturally arising Foxp3-expressing CD25+CD4+ regulatory T cells in immunological tolerance to self and non-self

21 June 2018

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Atelocollagen-mediated synthetic small interfering RNA delivery for effective gene silencing in vitro and in vivo

21 June 2018

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CD4+CD25+ T regulatory cells dependent on ICOS promote regulation of effector cells in the prediabetic lesion

21 June 2018

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In vitro-expanded antigen-specific regulatory T cells suppress autoimmune diabetes

21 June 2018

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Processing and activation of lysosomal proteinases

21 June 2018

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Cathepsin S inhibitor prevents autoantigen presentation and autoimmunity

21 June 2018

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Hypoglycaemia: the limiting factor in the glycaemic management of Type I and Type II diabetes

21 June 2018

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Cathepsin L regulates CD4+ T cell selection independently of its effect on invariant chain: a role in the generation of positively selecting peptide ligands

21 June 2018

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A role for cathepsin L and cathepsin S in peptide generation for MHC class II presentation

21 June 2018

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MHC class I-restricted determinants on the glutamic acid decarboxylase 65 molecule induce spontaneous CTL activity

21 June 2018

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B7/CD28 costimulation is essential for the homeostasis of the CD4+CD25+ immunoregulatory T cells that control autoimmune diabetes

21 June 2018

1 reference

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Lysosomal cysteine proteases: more than scavengers

21 June 2018

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Inhibition mechanism of cathepsin L-specific inhibitors based on the crystal structure of papain-CLIK148 complex

21 June 2018

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Dipeptidyl peptidase I is required for the processing and activation of granzymes A and B in vivo

21 June 2018

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The NOD mouse model of type 1 diabetes: as good as it gets?

21 June 2018

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Dipeptidyl peptidase I and granzyme A are coordinately expressed during CD8+ T cell development and differentiation.

21 June 2018

1 reference

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Cathepsin L: critical role in Ii degradation and CD4 T cell selection in the thymus

21 June 2018

1 reference

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The nonobese diabetic mouse as a model of autoimmune diabetes: immune dysregulation gets the NOD.

21 June 2018

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The MHC class II-associated invariant chain: a molecule with multiple roles in MHC class II biosynthesis and antigen presentation to CD4+ T cells

21 June 2018

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Dipeptidyl peptidase I is enriched in granules of in vitro- and in vivo-activated cytotoxic T lymphocytes.

21 June 2018

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Expression of recombinant human granzyme B. A processing and activation role for dipeptidyl peptidase I.

21 June 2018

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Cyclophosphamide-induced diabetes in NOD/WEHI mice. Evidence for suppression in spontaneous autoimmune diabetes mellitus

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2943924

Cathepsin S is required for murine autoimmune myasthenia gravis pathogenesis

21 June 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0012894

Human recombinant pro-dipeptidyl peptidase I (cathepsin C) can be activated by cathepsins L and S but not by autocatalytic processing

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0012894

Splenic cathepsin L is maturated from the proform by interferon-gamma after immunization with exogenous antigens

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0012894

Drak2 overexpression results in increased beta-cell apoptosis after free fatty acid stimulation

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0012894

DcR3/TR6 Effectively Prevents Islet Primary Nonfunction After Transplantation

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0012894

Control of intestinal inflammation by regulatory T cells

21 January 2018

1 reference

12 December 2020

A selective inhibitor of dipeptidyl peptidase I impairs generation of CD8+ T cell cytotoxic effector function

1 reference

12 December 2020

Impaired invariant chain degradation and antigen presentation and diminished collagen-induced arthritis in cathepsin S null mice

1 reference

12 December 2020

Structure based development of novel specific inhibitors for cathepsin L and cathepsin S in vitro and in vivo

1 reference

12 December 2020

Cyclophosphamide-induced type-1 diabetes in the NOD mouse is associated with a reduction of CD4+CD25+Foxp3+ regulatory T cells

1 reference

12 December 2020

Promotion of spontaneous diabetes in non-obese diabetes-prone mice by cyclophosphamide

1 reference

12 December 2020

Prevention of spontaneous autoimmune diabetes in NOD mice by transferring in vitro antigen-pulsed syngeneic dendritic cells

1 reference

12 December 2020

Defective CD8+ T Cell Peripheral Tolerance in Nonobese Diabetic Mice

1 reference

12 December 2020

10.1371/JOURNAL.PONE.0012894

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28 July 2017

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28 July 2017

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