Neutralization of the γ-secretase activity by monoclonal antibody against extracellular domain of nicastrin. (Q33759792)

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6 February 2020

title

Neutralization of the γ-secretase activity by monoclonal antibody against extracellular domain of nicastrin (English)

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6 February 2020

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2

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6 February 2020

Taisuke Tomita

15

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6 February 2020

author name string

I Hayashi

1

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6 February 2020

Y Urano

3

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6 February 2020

Y Miyake

4

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6 February 2020

J Takagi

5

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6 February 2020

M Sakata-Yanagimoto

6

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6 February 2020

H Iwanari

7

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6 February 2020

S Osawa

8

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6 February 2020

Y Morohashi

9

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6 February 2020

T Li

10

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6 February 2020

P C Wong

11

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6 February 2020

S Chiba

12

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6 February 2020

T Kodama

13

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6 February 2020

T Hamakubo

14

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6 February 2020

T Iwatsubo

16

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6 February 2020

language of work or name

English

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publication date

4 July 2011

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6 February 2020

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6 February 2020

volume

31

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6 February 2020

issue

6

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6 February 2020

page(s)

787-798

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https://scigraph.springernature.com/pub.10.1038/onc.2011.265

6 February 2020

exact match

0 references

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Glu-333 of nicastrin directly participates in gamma-secretase activity

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Glu(332) in the Nicastrin ectodomain is essential for gamma-secretase complex maturation but not for its activity

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21 June 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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ErbB-2 inhibition activates Notch-1 and sensitizes breast cancer cells to a gamma-secretase inhibitor

21 January 2018

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31 March 2020

Identifiers

DOI

10.1038/ONC.2011.265

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21725355%20AND%20SRC:MED&resulttype=core&format=json

Dimensions Publication ID

6 February 2020

0 references

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21725355%20AND%20SRC:MED&resulttype=core&format=json

6 February 2020

1 reference