Ezh2 regulates transcriptional and posttranslational expression of T-bet and promotes Th1 cell responses mediating aplastic anemia in mice (Q33824617)

29 July 2017

title

Ezh2 regulates transcriptional and posttranslational expression of T-bet and promotes Th1 cell responses mediating aplastic anemia in mice (English)

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29 July 2017

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11

Elizabeth Hexner

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29 July 2017

Qing Tong

1

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29 July 2017

Shan He

2

1 reference

29 July 2017

Fang Xie

3

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29 July 2017

Kazuhiro Mochizuki

4

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29 July 2017

Yongnian Liu

5

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29 July 2017

Izumi Mochizuki

6

1 reference

29 July 2017

Lijun Meng

7

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29 July 2017

Hongxing Sun

8

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29 July 2017

Yanyun Zhang

9

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29 July 2017

Yajun Guo

10

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29 July 2017

Yi Zhang

12

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29 July 2017

language of work or name

English

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publication date

23 April 2014

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29 July 2017

published in

Journal of Immunology

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29 July 2017

volume

192

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29 July 2017

issue

11

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29 July 2017

page(s)

5012-5022

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The histone methyltransferase Ezh2 is a crucial epigenetic regulator of allogeneic T-cell responses mediating graft-versus-host disease

29 July 2017

cites work

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4 July 2018

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4 July 2018

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4 July 2018

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4 July 2018

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4 July 2018

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4 July 2018

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Coordinated but physically separable interaction with H3K27-demethylase and H3K4-methyltransferase activities are required for T-box protein-mediated activation of developmental gene expression

4 July 2018

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4 July 2018

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4 July 2018

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4 July 2018

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4 July 2018

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4 July 2018

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4 July 2018

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4 July 2018

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4 July 2018

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4 July 2018

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T-bet, a Th1 transcription factor, is up-regulated in T cells from patients with aplastic anemia

4 July 2018

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4 July 2018

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EZH2 and histone 3 trimethyl lysine 27 associated with Il4 and Il13 gene silencing in Th1 cells

4 July 2018

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Conditional deletion of Gata3 shows its essential function in T(H)1-T(H)2 responses.

4 July 2018

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4 July 2018

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NF-Y cooperates with USF1/2 to induce the hematopoietic expression of HOXB4

4 July 2018

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The polycomb group protein EZH2 is involved in progression of prostate cancer

4 July 2018

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STAT4 serine phosphorylation is critical for IL-12-induced IFN-gamma production but not for cell proliferation

4 July 2018

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Preterminal host dendritic cells in irradiated mice prime CD8+ T cell-mediated acute graft-versus-host disease

4 July 2018

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Limited heterogeneity of T cell receptor BV usage in aplastic anemia

4 July 2018

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A novel transcription factor, T-bet, directs Th1 lineage commitment

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4075972

Hematopoietic cell destruction by immune mechanisms in acquired aplastic anemia

4 July 2018

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Involvement of heat shock protein 90 in the degradation of mutant insulin receptors by the proteasome.

4 July 2018

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The pathophysiology of acquired aplastic anemia

4 July 2018

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Cutting edge: Smad2 and Smad4 regulate TGF-β-mediated Il9 gene expression via EZH2 displacement

4 July 2018

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Drugs for ‘protein clouds’: targeting intrinsically disordered transcription factors

29 October 2018

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Dynamic changes in histone-methylation 'marks' across the locus encoding interferon-gamma during the differentiation of T helper type 2 cells

29 October 2018

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Polycomb group protein ezh2 controls actin polymerization and cell signaling.

29 October 2018

1 reference

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Bystander destruction of hematopoietic progenitor and stem cells in a mouse model of infusion-induced bone marrow failure.

29 October 2018

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29 October 2018

1 reference

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Inhibition of Th1 Development Mediated by GATA-3 through an IL-4-Independent Mechanism

29 October 2018

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12 December 2020

Unconventional association of the polycomb group proteins with cytokine genes in differentiated T helper cells

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12 December 2020

GATA-3 suppresses Th1 development by downregulation of Stat4 and not through effects on IL-12Rbeta2 chain or T-bet

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12 December 2020

Efficient and rapid induction of a chronic myelogenous leukemia-like myeloproliferative disease in mice receiving P210 bcr/abl-transduced bone marrow

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The binding activity of Mel-18 at the Il17a promoter is regulated by the integrated signals of the TCR and polarizing cytokines

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12 December 2020

Intracellular interferon-gamma in circulating and marrow T cells detected by flow cytometry and the response to immunosuppressive therapy in patients with aplastic anemia

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12 December 2020

Graft-versus-host disease

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12 December 2020

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12 December 2020

Minor antigen h60-mediated aplastic anemia is ameliorated by immunosuppression and the infusion of regulatory T cells

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12 December 2020

Identifiers

DOI

10.4049/JIMMUNOL.1302943

1 reference

29 July 2017

1 reference

29 July 2017

1 reference