Genetics of type 2 diabetes in European populations (Q34032738)

30 July 2017

title

Genetics of type 2 diabetes in European populations (English)

1 reference

30 July 2017

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2

Frank B Hu

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30 July 2017

Qibin Qi

1

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30 July 2017

publication date

1 September 2012

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30 July 2017

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30 July 2017

volume

4

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30 July 2017

issue

3

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30 July 2017

page(s)

203-212

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Gene-environment interactions in the development of type 2 diabetes: recent progress and continuing challenges

30 July 2017

cites work

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5 July 2018

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Combined effects of 19 common variations on type 2 diabetes in Chinese: results from two community-based studies

5 July 2018

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Interactions of dietary whole-grain intake with fasting glucose- and insulin-related genetic loci in individuals of European descent: a meta-analysis of 14 cohort studies

5 July 2018

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Twelve type 2 diabetes susceptibility loci identified through large-scale association analysis

5 July 2018

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Type 2 diabetes risk alleles near ADCY5, CDKAL1 and HHEX-IDE are associated with reduced birthweight.

5 July 2018

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Genetic variants at 2q24 are associated with susceptibility to type 2 diabetes

5 July 2018

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Variants in ADCY5 and near CCNL1 are associated with fetal growth and birth weight

5 July 2018

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Detailed physiologic characterization reveals diverse mechanisms for novel genetic Loci regulating glucose and insulin metabolism in humans

5 July 2018

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New genetic loci implicated in fasting glucose homeostasis and their impact on type 2 diabetes risk

5 July 2018

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Gene variants in the novel type 2 diabetes loci CDC123/CAMK1D, THADA, ADAMTS9, BCL11A, and MTNR1B affect different aspects of pancreatic beta-cell function

5 July 2018

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Variant near ADAMTS9 known to associate with type 2 diabetes is related to insulin resistance in offspring of type 2 diabetes patients--EUGENE2 study

5 July 2018

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Joint effects of common genetic variants on the risk for type 2 diabetes in U.S. men and women of European ancestry

5 July 2018

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Genetic predisposition, Western dietary pattern, and the risk of type 2 diabetes in men.

5 July 2018

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Genetic variant in the IGF2BP2 gene may interact with fetal malnutrition to affect glucose metabolism

5 July 2018

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TCF7L2, dietary carbohydrate, and risk of type 2 diabetes in US women

5 July 2018

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A variant near MTNR1B is associated with increased fasting plasma glucose levels and type 2 diabetes risk

5 July 2018

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Common variant in MTNR1B associated with increased risk of type 2 diabetes and impaired early insulin secretion

5 July 2018

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Variants in MTNR1B influence fasting glucose levels

5 July 2018

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Common variants at 30 loci contribute to polygenic dyslipidemia

5 July 2018

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Clinical risk factors, DNA variants, and the development of type 2 diabetes

5 July 2018

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Genotype score in addition to common risk factors for prediction of type 2 diabetes

5 July 2018

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Predicting type 2 diabetes based on polymorphisms from genome-wide association studies: a population-based study

5 July 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3422419

Common missense variant in the glucokinase regulatory protein gene is associated with increased plasma triglyceride and C-reactive protein but lower fasting glucose concentrations

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3422419

Common variants in CDKAL1, CDKN2A/B, IGF2BP2, SLC30A8, and HHEX/IDE genes are associated with type 2 diabetes and impaired fasting glucose in a Chinese Han population

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3422419

Assessing the combined impact of 18 common genetic variants of modest effect sizes on type 2 diabetes risk

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3422419

Post genome-wide association studies of novel genes associated with type 2 diabetes show gene-gene interaction and high predictive value

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3422419

Meta-analysis of genome-wide association data and large-scale replication identifies additional susceptibility loci for type 2 diabetes

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3422419

Replication of the association between variants in WFS1 and risk of type 2 diabetes in European populations

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3422419

The GCKR rs780094 polymorphism is associated with elevated fasting serum triacylglycerol, reduced fasting and OGTT-related insulinaemia, and reduced risk of type 2 diabetes

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3422419

Common variants of the novel type 2 diabetes genes CDKAL1 and HHEX/IDE are associated with decreased pancreatic beta-cell function

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3422419

Polymorphisms within novel risk loci for type 2 diabetes determine beta-cell function

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3422419

Mechanisms by which common variants in the TCF7L2 gene increase risk of type 2 diabetes

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3422419

Impaired glucagon-like peptide-1-induced insulin secretion in carriers of transcription factor 7-like 2 (TCF7L2) gene polymorphisms.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3422419

Common variants in WFS1 confer risk of type 2 diabetes

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3422419

Genome-wide association study of 14,000 cases of seven common diseases and 3,000 shared controls

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3422419

Variation in FTO contributes to childhood obesity and severe adult obesity

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3422419

Replication of genome-wide association signals in UK samples reveals risk loci for type 2 diabetes

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3422419

A genome-wide association study of type 2 diabetes in Finns detects multiple susceptibility variants

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3422419

Genome-wide association analysis identifies loci for type 2 diabetes and triglyceride levels

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3422419

A variant in CDKAL1 influences insulin response and risk of type 2 diabetes

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3422419

A common variant in the FTO gene is associated with body mass index and predisposes to childhood and adult obesity

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3422419

A genome-wide association study identifies novel risk loci for type 2 diabetes

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3422419

The effects of the Pro12Ala polymorphism of the peroxisome proliferator-activated receptor-gamma2 gene on glucose/insulin metabolism interact with prenatal exposure to famine

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3422419

Diabetic Goto Kakizaki rats as well as type 2 diabetic patients show a decreased diurnal serum melatonin level and an increased pancreatic melatonin-receptor status

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3422419

Variant of transcription factor 7-like 2 (TCF7L2) gene confers risk of type 2 diabetes

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3422419

ZnT-8, a pancreatic beta-cell-specific zinc transporter

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3422419

Dual specificity mitogen-activated protein (MAP) kinase phosphatase-4 plays a potential role in insulin resistance

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3422419

The thrifty phenotype hypothesis

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3422419

Molecular mechanisms and clinical pathophysiology of maturity-onset diabetes of the young

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3422419

The common PPARgamma Pro12Ala polymorphism is associated with decreased risk of type 2 diabetes

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3422419

A Pro12Ala substitution in PPARgamma2 associated with decreased receptor activity, lower body mass index and improved insulin sensitivity

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3422419

A gene encoding a transmembrane protein is mutated in patients with diabetes mellitus and optic atrophy (Wolfram syndrome)

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3422419

The genetics of human noninsulin-dependent (type 2) diabetes mellitus

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3422419

Large-scale association studies of variants in genes encoding the pancreatic beta-cell KATP channel subunits Kir6.2 (KCNJ11) and SUR1 (ABCC8) confirm that the KCNJ11 E23K variant is associated with type 2 diabetes

5 July 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1753-0407.2012.00224.X

Genetic advances of type 2 diabetes in Chinese populations

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1753-0407.2012.00224.X

Two variants on chromosome 17 confer prostate cancer risk and the one in TCF2 protects against type 2 diabetes

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1753-0407.2012.00224.X

The common SLC30A8 Arg325Trp variant is associated with reduced first-phase insulin release in 846 non-diabetic offspring of type 2 diabetes patients--the EUGENE2 study

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1753-0407.2012.00224.X

Studies of association of variants near the HHEX, CDKN2A/B, and IGF2BP2 genes with type 2 diabetes and impaired insulin release in 10,705 Danish subjects: validation and extension of genome-wide association studies.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1753-0407.2012.00224.X

Genetic variant near IRS1 is associated with type 2 diabetes, insulin resistance and hyperinsulinemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1753-0407.2012.00224.X

Variants in KCNQ1 are associated with susceptibility to type 2 diabetes mellitus.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1753-0407.2012.00224.X

Impact of common type 2 diabetes risk polymorphisms in the DESIR prospective study

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1753-0407.2012.00224.X

Association of GCKR rs780094, alone or in combination with GCK rs1799884, with type 2 diabetes and related traits in a Han Chinese population

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1753-0407.2012.00224.X

Variants at DGKB/TMEM195, ADRA2A, GLIS3 and C2CD4B loci are associated with reduced glucose-stimulated beta cell function in middle-aged Danish people

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1753-0407.2012.00224.X

The E23K variant of Kir6.2 associates with impaired post-OGTT serum insulin response and increased risk of type 2 diabetes

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1753-0407.2012.00224.X

Impact of polymorphisms in WFS1 on prediabetic phenotypes in a population-based sample of middle-aged people with normal and abnormal glucose regulation

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1753-0407.2012.00224.X

Common variants in KCNQ1 are associated with type 2 diabetes and impaired fasting glucose in a Chinese Han population.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1753-0407.2012.00224.X

Lack of significant effects of the type 2 diabetes susceptibility loci JAZF1, CDC123/CAMK1D, NOTCH2, ADAMTS9, THADA, and TSPAN8/LGR5 on diabetes and quantitative metabolic traits

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1753-0407.2012.00224.X

Birth weight and subsequent risk of type 2 diabetes: a meta-analysis

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1753-0407.2012.00224.X

Combined effects of 17 common genetic variants on type 2 diabetes risk in a Han Chinese population

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1753-0407.2012.00224.X

Dietary fat intake and polymorphisms at the PPARG locus modulate BMI and type 2 diabetes risk in the D.E.S.I.R. prospective study.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1753-0407.2012.00224.X

Interaction between prenatal growth and high-risk genotypes in the development of type 2 diabetes

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1753-0407.2012.00224.X

Association testing of novel type 2 diabetes risk alleles in the JAZF1, CDC123/CAMK1D, TSPAN8, THADA, ADAMTS9, and NOTCH2 loci with insulin release, insulin sensitivity, and obesity in a population-based sample of 4,516 glucose-tolerant middle-aged D

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3422419

Putative roles of melatonin in glucose regulation.

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3422419

Evaluation of Common Variants in the Six Known Maturity-Onset Diabetes of the Young (MODY) Genes for Association With Type 2 Diabetes

29 October 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1753-0407.2012.00224.X

SNPs in KCNQ1 are associated with susceptibility to type 2 diabetes in East Asian and European populations

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1753-0407.2012.00224.X

Combined analysis of 19 common validated type 2 diabetes susceptibility gene variants shows moderate discriminative value and no evidence of gene–gene interaction

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1753-0407.2012.00224.X

The Effects of the Pro12Ala Polymorphism of the Peroxisome Proliferator-Activated Receptor- 2 Gene on Glucose/Insulin Metabolism Interact With Prenatal Exposure to Famine

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1753-0407.2012.00224.X

The genetics of type 2 diabetes

21 January 2018

1 reference

12 December 2020

Genetics of diabetes in Nauru: Effects of foreign admixture, HLA antigens and the insulin-gene-linked polymorphism

1 reference

12 December 2020

Evidence for a circadian rhythm of insulin secretion

1 reference

12 December 2020

Missense mutations in the pancreatic islet beta cell inwardly rectifying K+ channel gene (KIR6.2/BIR): a meta-analysis suggests a role in the polygenic basis of Type II diabetes mellitus in Caucasians

1 reference

12 December 2020

Analysis of 32 common susceptibility genetic variants and their combined effect in predicting risk of Type 2 diabetes and related traits in Indians

1 reference

12 December 2020

10.1111/J.1753-0407.2012.00224.X

Identifiers

DOI

1 reference

release_ah6huhgm6fgrbh5khznzcl2cwe

30 July 2017

Fatcat ID

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/ah6huhgm6fgrbh5khznzcl2cwe

24 November 2022

mapped directly with Wikidata item

PMC publication ID

3422419

1 reference

30 July 2017

1 reference