Transcriptional/epigenetic regulator CBP/p300 in tumorigenesis: structural and functional versatility in target recognition. (Q34035076)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23307074%20AND%20SRC:MED&resulttype=core&format=json

22 February 2020

review article

1 reference

title

Transcriptional/epigenetic regulator CBP/p300 in tumorigenesis: structural and functional versatility in target recognition (English)

1 reference

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22 February 2020

1

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22 February 2020

Christopher B Marshall

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23307074%20AND%20SRC:MED&resulttype=core&format=json

22 February 2020

Mitsuhiko Ikura

3

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22 February 2020

author name string

Feng Wang

1

1 reference

30 July 2017

Christopher B Marshall

2

1 reference

30 July 2017

Mitsuhiko Ikura

3

1 reference

30 July 2017

11 January 2013

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23307074%20AND%20SRC:MED&resulttype=core&format=json

Cellular and Molecular Life Sciences

22 February 2020

published in

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23307074%20AND%20SRC:MED&resulttype=core&format=json

22 February 2020

volume

70

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22 February 2020

issue

21

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22 February 2020

page(s)

3989-4008

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https://scigraph.springernature.com/pub.10.1007/s00018-012-1254-4

22 February 2020

exact match

0 references

cites work

Transcriptional coactivators in yeast and beyond

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-1254-4

The general transcription machinery and general cofactors

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-1254-4

Transcriptional activation by recruitment

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-1254-4

Transcription factor ATF interacts with the TATA factor to facilitate establishment of a preinitiation complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-1254-4

TAFII mutations disrupt Dorsal activation in the Drosophila embryo

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-1254-4

Family of proteins that interact with TFIID and regulate promoter activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-1254-4

Isolation of coactivators associated with the TATA-binding protein that mediate transcriptional activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-1254-4

A multiprotein mediator of transcriptional activation and its interaction with the C-terminal repeat domain of RNA polymerase II.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-1254-4

Nucleosomes, linker DNA, and linker histone form a unique structural motif that directs the higher-order folding and compaction of chromatin

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-1254-4

Transcriptional coactivator complexes

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-1254-4

Biological control through regulated transcriptional coactivators

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-1254-4

The CBP co-activator is a histone acetyltransferase

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-1254-4

The transcriptional coactivators p300 and CBP are histone acetyltransferases

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-1254-4

The p300/CBP family: integrating signals with transcription factors and chromatin

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-1254-4

CBP and p300: HATs for different occasions

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-1254-4

Cellular targets for transformation by the adenovirus E1A proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-1254-4

Molecular cloning and functional analysis of the adenovirus E1A-associated 300-kD protein (p300) reveals a protein with properties of a transcriptional adaptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-1254-4

Phosphorylated CREB binds specifically to the nuclear protein CBP

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-1254-4

Nuclear protein CBP is a coactivator for the transcription factor CREB

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-1254-4

Activation of cAMP and mitogen responsive genes relies on a common nuclear factor

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-1254-4

Functional role of p35srj, a novel p300/CBP binding protein, during transactivation by HIF-1

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-1254-4

Solution structure of the TAZ2 (CH3) domain of the transcriptional adaptor protein CBP

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-1254-4

Phosphorylation of CREB at Ser-133 induces complex formation with CREB-binding protein via a direct mechanism

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-1254-4

Activation of the cyclin D1 gene by the E1A-associated protein p300 through AP-1 inhibits cellular apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-1254-4

A small domain of CBP/p300 binds diverse proteins: solution structure and functional studies

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-1254-4

Mutual synergistic folding in recruitment of CBP/p300 by p160 nuclear receptor coactivators

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-1254-4

Nucleosome binding by the bromodomain and PHD finger of the transcriptional cofactor p300.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-1254-4

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-1254-4

Stimulation of c-MYC transcriptional activity and acetylation by recruitment of the cofactor CBP.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-1254-4

The E6 protein of human papillomavirus type 16 binds to and inhibits co-activation by CBP and p300.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-1254-4

Recruitment of p300/CBP in p53-dependent signal pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-1254-4

Binding and modulation of p53 by p300/CBP coactivators

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-1254-4

DAF-16 recruits the CREB-binding protein coactivator complex to the insulin-like growth factor binding protein 1 promoter in HepG2 cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-1254-4

MLL-AFX requires the transcriptional effector domains of AFX to transform myeloid progenitors and transdominantly interfere with forkhead protein function

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-1254-4

Common mechanism for oncogenic activation of MLL by forkhead family proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-1254-4

Two contact regions between Stat1 and CBP/p300 in interferon gamma signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-1254-4

Cooperation of Stat2 and p300/CBP in signalling induced by interferon-alpha

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-1254-4

An essential role for p300/CBP in the cellular response to hypoxia

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-1254-4

Signal transduction in hypoxic cells: inducible nuclear translocation and recruitment of the CBP/p300 coactivator by the hypoxia-inducible factor-1alpha

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-1254-4

CBP/p300 interact with and function as transcriptional coactivators of BRCA1

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-1254-4

MAP kinase-dependent transcriptional coactivation by Elk-1 and its cofactor CBP.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-1254-4

The tumor suppressor Smad4/DPC4 and transcriptional adaptor CBP/p300 are coactivators for smad3 in TGF-beta-induced transcriptional activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-1254-4

Interaction and functional cooperation of the leukemia-associated factors AML1 and p300 in myeloid cell differentiation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-1254-4

CBP/p300 histone acetyl-transferase activity is important for the G1/S transition

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-1254-4

Structural basis of CBP/p300 recruitment in leukemia induction by E2A-PBX1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-1254-4

Four domains of p300 each bind tightly to a sequence spanning both transactivation subdomains of p53

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-1254-4

Structures of KIX domain of CBP in complex with two FOXO3a transactivation domains reveal promiscuity and plasticity in coactivator recruitment

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-1254-4

Role of CBP/P300 in nuclear receptor signalling

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-1254-4

CREB binding protein is a coactivator for the androgen receptor and mediates cross-talk with AP-1

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-1254-4

p300 is a component of an estrogen receptor coactivator complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-1254-4

Adaptor-mediated recruitment of RNA polymerase II to a signal-dependent activator

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-1254-4

RNA helicase A mediates association of CBP with RNA polymerase II

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-1254-4

A human RNA polymerase II complex containing factors that modify chromatin structure

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-1254-4

Efficient recruitment of TFIIB and CBP-RNA polymerase II holoenzyme by an interferon-beta enhanceosome in vitro

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-1254-4

Specificity of cyclin E-Cdk2, TFIIB, and E1A interactions with a common domain of the p300 coactivator

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-1254-4

Acetylation of general transcription factors by histone acetyltransferases

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-1254-4

Distinct GCN5/PCAF-containing complexes function as co-activators and are involved in transcription factor and global histone acetylation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-1254-4

Structural Basis of Site-Specific Histone Recognition by the Bromodomains of Human Coactivators PCAF and CBP/p300

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-1254-4

Distinct roles of GCN5/PCAF-mediated H3K9ac and CBP/p300-mediated H3K18/27ac in nuclear receptor transactivation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-1254-4

The histone acetylase PCAF is a nuclear receptor coactivator.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-1254-4

IFN-Stimulated transcription through a TBP-free acetyltransferase complex escapes viral shutoff

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-1254-4

A p300/CBP-associated factor that competes with the adenoviral oncoprotein E1A

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-1254-4

CBP/p300 is a cell type-specific modulator of CLOCK/BMAL1-mediated transcription

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-1254-4

Mammalian GCN5 and P/CAF acetyltransferases have homologous amino-terminal domains important for recognition of nucleosomal substrates

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-1254-4

Regulation of transforming growth factor-beta and bone morphogenetic protein signalling by transcriptional coactivator GCN5.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-1254-4

GCN5 and p300 share essential functions during early embryogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-1254-4

The phosphorylation status of a cyclic AMP-responsive activator is modulated via a chromatin-dependent mechanism

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-1254-4

Solution Structure of the KIX Domain of CBP Bound to the Transactivation Domain of CREB: A Model for Activator:Coactivator Interactions

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-1254-4

Mechanism of coupled folding and binding of an intrinsically disordered protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-1254-4

Binding-induced folding of a natively unstructured transcription factor.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-1254-4

Roles of phosphorylation and helix propensity in the binding of the KIX domain of CREB-binding protein by constitutive (c-Myb) and inducible (CREB) activators

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-1254-4

Solution structure of the KIX domain of CBP bound to the transactivation domain of c-Myb

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-1254-4

Cooperativity in transcription factor binding to the coactivator CREB-binding protein (CBP). The mixed lineage leukemia protein (MLL) activation domain binds to an allosteric site on the KIX domain

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-1254-4

Structural Basis for Cooperative Transcription Factor Binding to the CBP Coactivator

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-1254-4

Adenovirus E1A proteins inhibit activation of transcription by p53.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-1254-4

Synergistic interplay between promoter recognition and CBP/p300 coactivator recruitment by FOXO3a

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-1254-4

Mapping the interactions of the p53 transactivation domain with the KIX domain of CBP

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-1254-4

HTLV-1 HBZ protein deregulates interactions between cellular factors and the KIX domain of p300/CBP.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-1254-4

Structurally distinct modes of recognition of the KIX domain of CBP by Jun and CREB.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-1254-4

Regulated recruitment of tumor suppressor BRCA1 to the p21 gene by coactivator methylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-1254-4

E2A-PBX1 interacts directly with the KIX domain of CBP/p300 in the induction of proliferation in primary hematopoietic cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-1254-4

Molecular characterization of HTLV-1 Tax interaction with the KIX domain of CBP/p300.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-1254-4

SREBP transcriptional activity is mediated through an interaction with the CREB-binding protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-1254-4

CBP/p300 TAZ1 domain forms a structured scaffold for ligand binding

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-1254-4

ZZ domain of CBP: an unusual zinc finger fold in a protein interaction module

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-1254-4

Structure of the Taz2 domain of p300: insights into ligand binding

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-1254-4

The PHD type zinc finger is an integral part of the CBP acetyltransferase domain

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-1254-4

Structural insights into human KAP1 PHD finger-bromodomain and its role in gene silencing

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-1254-4

The PHD Finger of Human UHRF1 Reveals a New Subgroup of Unmethylated Histone H3 Tail Readers

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-1254-4

Role of CBP in regulating HIF-1-mediated activation of transcription.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-1254-4

Cooperative regulation of p53 by modulation of ternary complex formation with CBP/p300 and HDM2

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-1254-4

Structural basis for p300 Taz2-p53 TAD1 binding and modulation by phosphorylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-1254-4

Two distinct motifs within the p53 transactivation domain bind to the Taz2 domain of p300 and are differentially affected by phosphorylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-1254-4

Quantitative analysis of multisite protein-ligand interactions by NMR: binding of intrinsically disordered p53 transactivation subdomains with the TAZ2 domain of CBP.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-1254-4

Structural basis for Hif-1 alpha /CBP recognition in the cellular hypoxic response

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-1254-4

The essential role of Cited2, a negative regulator for HIF-1alpha, in heart development and neurulation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-1254-4

Interaction of the TAZ1 domain of the CREB-binding protein with the activation domain of CITED2: regulation by competition between intrinsically unstructured ligands for non-identical binding sites

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-1254-4

Structural basis for negative regulation of hypoxia-inducible factor-1alpha by CITED2

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-1254-4

Differential use of CREB binding protein-coactivator complexes

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-1254-4

cAMP-independent activation of the adenovirus type 12 E2 promoter correlates with the recruitment of CREB-1/ATF-1, E1A(12S), and CBP to the E2-CRE

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-1254-4

Structural basis for subversion of cellular control mechanisms by the adenoviral E1A oncoprotein

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-1254-4

Structural basis for recruitment of CBP/p300 coactivators by STAT1 and STAT2 transactivation domains

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-1254-4

MEF2: a calcium-dependent regulator of cell division, differentiation and death

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-1254-4

Molecular mechanisms of myogenic coactivation by p300: direct interaction with the activation domain of MyoD and with the MADS box of MEF2C

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-1254-4

Integration of calcineurin and MEF2 signals by the coactivator p300 during T-cell apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-1254-4

Control of cardiac-specific transcription by p300 through myocyte enhancer factor-2D

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-1254-4

Structure of p300 bound to MEF2 on DNA reveals a mechanism of enhanceosome assembly

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-1254-4

Crystal structure of IRF-3 in complex with CBP.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-1254-4

Structure of the p53 Transactivation Domain in Complex with the Nuclear Receptor Coactivator Binding Domain of CREB Binding Protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-1254-4

Synergistic, p160 coactivator-dependent enhancement of estrogen receptor function by CARM1 and p300.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-1254-4

Packing, specificity, and mutability at the binding interface between the p160 coactivator and CREB-binding protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-1254-4

Conformational selection in the molten globule state of the nuclear coactivator binding domain of CBP

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-1254-4

Conformational selection or induced fit: a flux description of reaction mechanism

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-1254-4

The nuclear receptor ligand-binding domain: structure and function.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-1254-4

A signature motif in transcriptional co-activators mediates binding to nuclear receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-1254-4

Intrinsically unstructured proteins and their functions

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-1254-4

Graded enhancement of p53 binding to CREB-binding protein (CBP) by multisite phosphorylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-1254-4

Structural and functional characterization of an atypical activation domain in erythroid Kruppel-like factor (EKLF)

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-1254-4

Biochemical and structural characterization of an intramolecular interaction in FOXO3a and its binding with p53

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-1254-4

Regulation of transactivation-independent proapoptotic activity of p53 by FOXO3a

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-1254-4

The pro-longevity gene FoxO3 is a direct target of the p53 tumor suppressor.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-1254-4

Modulation of STAT signaling by STAT-interacting proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-1254-4

Integration of Smad and forkhead pathways in the control of neuroepithelial and glioblastoma cell proliferation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-1254-4

Homotypic clusters of transcription factor binding sites are a key component of human promoters and enhancers

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-1254-4

FOXO3a is activated in response to hypoxic stress and inhibits HIF1-induced apoptosis via regulation of CITED2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-1254-4

PTEN regulates p300-dependent hypoxia-inducible factor 1 transcriptional activity through Forkhead transcription factor 3a (FOXO3a).

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-1254-4

Functional anthology of intrinsic disorder. 3. Ligands, post-translational modifications, and diseases associated with intrinsically disordered proteins.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-1254-4

Differential activation of CREB by Ca2+/calmodulin-dependent protein kinases type II and type IV involves phosphorylation of a site that negatively regulates activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-1254-4

Direct regulation of CREB transcriptional activity by ATM in response to genotoxic stress

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-1254-4

Coregulated ataxia telangiectasia-mutated and casein kinase sites modulate cAMP-response element-binding protein-coactivator interactions in response to DNA damage

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-1254-4

CREB and the CRTC co-activators: sensors for hormonal and metabolic signals

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-1254-4

Regulation by phosphorylation of the relative affinities of the N-terminal transactivation domains of p53 for p300 domains and Mdm2

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-1254-4

Modulation of p300 binding by posttranslational modifications of the C-terminal activation domain of hypoxia-inducible factor-1alpha

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-1254-4

A novel mechanism for cyclic adenosine 3',5'-monophosphate regulation of gene expression by CREB-binding protein.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-1254-4

Insulin regulation of hepatic gluconeogenesis through phosphorylation of CREB-binding protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-1254-4

CREB binding protein recruitment to the transcription complex requires growth factor-dependent phosphorylation of its GF box.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-1254-4

A peek into the complex realm of histone phosphorylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-1254-4

Epigenetic regulation by histone methylation and histone variants

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-1254-4

Histone ubiquitination: triggering gene activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-1254-4

Histone sumoylation is associated with transcriptional repression

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-1254-4

Functions of site-specific histone acetylation and deacetylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-1254-4

Translating the Histone Code

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-1254-4

Chromatin remodeling and cancer, Part I: Covalent histone modifications

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-1254-4

Histone acetylation increases chromatin accessibility

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-1254-4

Overlapping but distinct patterns of histone acetylation by the human coactivators p300 and PCAF within nucleosomal substrates

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-1254-4

CBP/p300-mediated acetylation of histone H3 on lysine 56

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-1254-4

The structural basis of protein acetylation by the p300/CBP transcriptional coactivator

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-1254-4

Structure and chemistry of the p300/CBP and Rtt109 histone acetyltransferases: implications for histone acetyltransferase evolution and function

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-1254-4

A viral mechanism for inhibition of p300 and PCAF acetyltransferase activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-1254-4

A novel Rb- and p300-binding protein inhibits transactivation by MyoD

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-1254-4

Cells degrade a novel inhibitor of differentiation with E1A-like properties upon exiting the cell cycle

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-1254-4

Increased EID1 nuclear translocation impairs synaptic plasticity and memory function associated with pathogenesis of Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-1254-4

Structural mechanism of the bromodomain of the coactivator CBP in p53 transcriptional activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-1254-4

Synergistic activation of transcription by CBP and p53

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-1254-4

Myocyte enhancer factor 2 acetylation by p300 enhances its DNA binding activity, transcriptional activity, and myogenic differentiation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-1254-4

Acetylation of Smad2 by the co-activator p300 regulates activin and transforming growth factor beta response

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-1254-4

Regulation of FoxO activity by CBP/p300-mediated acetylation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-1254-4

The coactivator p300 directly acetylates the forkhead transcription factor Foxo1 and stimulates Foxo1-induced transcription

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-1254-4

Drosophila CBP represses the transcription factor TCF to antagonize Wingless signalling.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-1254-4

Broad thumbs and toes and facial abnormalities. A possible mental retardation syndrome

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-1254-4

Rubinstein-Taybi syndrome caused by a De Novo reciprocal translocation t(2;16)(q36.3;p13.3).

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-1254-4

Systematic in vivo structure-function analysis of p300 in hematopoiesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-1254-4

Frequent mutation of histone-modifying genes in non-Hodgkin lymphoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-1254-4

The translocation t(8;16)(p11;p13) of acute myeloid leukaemia fuses a putative acetyltransferase to the CREB-binding protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-1254-4

MOZ is fused to p300 in an acute monocytic leukemia with t(8;22).

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-1254-4

MLL is fused to CBP, a histone acetyltransferase, in therapy-related acute myeloid leukemia with a t(11;16)(q23;p13.3).

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-1254-4

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-1254-4

Selective roles for cAMP response element-binding protein binding protein and p300 protein as coregulators for androgen-regulated gene expression in advanced prostate cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-1254-4

A role for p300/CREB binding protein genes in promoting cancer progression in colon cancer cell lines with microsatellite instability

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-1254-4

Targeted inhibition of β-catenin/CBP signaling ameliorates renal interstitial fibrosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-1254-4

Interactions between β-catenin and transforming growth factor-β signaling pathways mediate epithelial-mesenchymal transition and are dependent on the transcriptional co-activator cAMP-response element-binding protein (CREB)-binding protein (CBP).

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-1254-4

The gamma catenin/CBP complex maintains survivin transcription in β-catenin deficient/depleted cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-1254-4

HIV-1 tat transactivator recruits p300 and CREB-binding protein histone acetyltransferases to the viral promoter

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-1254-4

CBP gene transfer increases BDNF levels and ameliorates learning and memory deficits in a mouse model of Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-1254-4

Pancreas duodenum homeobox-1 transcriptional activation requires interactions with p300

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-1254-4

Spatiotemporal expression of histone acetyltransferases, p300 and CBP, in developing embryonic hearts

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-1254-4

Quantitative control of adaptive cardiac hypertrophy by acetyltransferase p300.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-1254-4

Transcriptional switches: chemical approaches to gene regulation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-1254-4

Curcumin, a novel p300/CREB-binding protein-specific inhibitor of acetyltransferase, represses the acetylation of histone/nonhistone proteins and histone acetyltransferase-dependent chromatin transcription

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-1254-4

21 January 2018

The targets of curcumin.

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-1254-4

Specific inhibition of p300-HAT alters global gene expression and represses HIV replication.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-1254-4

Mechanism of p300 specific histone acetyltransferase inhibition by small molecules

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-1254-4

The bromodomain interaction module

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-1254-4

Histone recognition and large-scale structural analysis of the human bromodomain family

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-1254-4

Interplay of bromodomain and histone acetylation in the regulation of p300-dependent genes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-1254-4

A Small Molecule Binding to the Coactivator CREB-Binding Protein Blocks Apoptosis in Cardiomyocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-1254-4

3,5-dimethylisoxazoles act as acetyl-lysine-mimetic bromodomain ligands

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-1254-4

Small molecule blockade of transcriptional coactivation of the hypoxia-inducible factor pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-1254-4

Direct inhibition of hypoxia-inducible transcription factor complex with designed dimeric epidithiodiketopiperazine

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-1254-4

Identification of small-molecule antagonists that inhibit an activator: coactivator interaction

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-1254-4

Discovery of a small-molecule inhibitor of the KIX-KID interaction

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-1254-4

Amphipathic small molecules mimic the binding mode and function of endogenous transcription factors

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-1254-4

Sekikaic acid and lobaric acid target a dynamic interface of the coactivator CBP/p300.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-1254-4

Prediction and Functional Analysis of Native Disorder in Proteins from the Three Kingdoms of Life

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-1254-4

The LxxLL motif: a multifunctional binding sequence in transcriptional regulation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-1254-4

Mapping acetylation sites in E2A identifies a conserved lysine residue in activation domain 1 that promotes CBP/p300 recruitment and transcriptional activation.

21 January 2018

1 reference

12 December 2020

CREB-binding protein activates transcription through multiple domains

1 reference

12 December 2020

Characterization of an E1A-CBP interaction defines a novel transcriptional adapter motif (TRAM) in CBP/p300

1 reference

12 December 2020

CBP-induced stimulation of c-Fos activity is abrogated by E1A.

1 reference

12 December 2020

Binding of transcription factor TFIID to the major late promoter during in vitro nucleosome assembly potentiates subsequent initiation by RNA polymerase II

1 reference

12 December 2020

CBP as a transcriptional coactivator of c-Myb

1 reference

12 December 2020

Gene dose-dependent control of hematopoiesis and hematologic tumor suppression by CBP

1 reference

12 December 2020

The t(11;16)(q23;p13) translocation in myelodysplastic syndrome fuses the MLL gene to the CBP gene

1 reference

12 December 2020

E2A proteins enhance the histone acetyltransferase activity of the transcriptional co-activators CBP and p300

1 reference

12 December 2020

Arylsulfonamide KCN1 inhibits in vivo glioma growth and interferes with HIF signaling by disrupting HIF-1α interaction with cofactors p300/CBP.

1 reference

12 December 2020

Acetylation of cAMP-responsive element-binding protein (CREB) by CREB-binding protein enhances CREB-dependent transcription

1 reference

12 December 2020

Stimulation of c-Jun activity by CBP: c-Jun residues Ser63/73 are required for CBP induced stimulation in vivo and CBP binding in vitro

1 reference

12 December 2020

All patients with the T(11;16)(q23;p13.3) that involves MLL and CBP have treatment-related hematologic disorders

1 reference

12 December 2020

p300 mediates cellular resistance to doxorubicin in bladder cancer.

1 reference

12 December 2020

Phosphorylation of p53 serine 15 increases interaction with CBP

1 reference

12 December 2020

Phosphorylation-induced transient intrinsic structure in the kinase-inducible domain of CREB facilitates its recognition by the KIX domain of CBP

1 reference

12 December 2020

Protein dynamics and conformational disorder in molecular recognition

1 reference

12 December 2020

p300 in prostate cancer proliferation and progression.

1 reference

12 December 2020

Variation in microdeletions of the cyclic AMP-responsive element-binding protein gene at chromosome band 16p13.3 in the Rubinstein-Taybi syndrome

1 reference

12 December 2020

CREB-binding protein and p300/CBP-associated factor are transcriptional coactivators of the p53 tumor suppressor protein

1 reference

12 December 2020

Inhibition of the acetyltransferases p300 and CBP reveals a targetable function for p300 in the survival and invasion pathways of prostate cancer cell lines

1 reference

12 December 2020

Novel MLL-CBP fusion transcript in therapy-related chronic myelomonocytic leukemia with a t(11;16)(q23;p13) chromosome translocation

1 reference

12 December 2020

10.1007/S00018-012-1254-4

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23307074%20AND%20SRC:MED&resulttype=core&format=json

22 February 2020

1 reference