Graded enhancement of p53 binding to CREB-binding protein (CBP) by multisite phosphorylation (Q34320186)

1 August 2017

Graded enhancement of p53 binding to CREB-binding protein (CBP) by multisite phosphorylation (English)

1 reference

1 August 2017

1 reference

5

1 reference

1 August 2017

Josephine C Ferreon

2

0 references

Munehito Arai

object named as

Munehito Arai

series ordinal

4

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author name string

Chul Won Lee

series ordinal

1

1 reference

PubMed ID

20962272

1 August 2017

Allan Chris M Ferreon

series ordinal

3

1 reference

PubMed ID

20962272

1 August 2017

language of work or name

English

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publication date

20 October 2010

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1 August 2017

6

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Proceedings of the National Academy of Sciences of the United States of America

inferred from page(s)

published in

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1 August 2017

107

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1 August 2017

45

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1 August 2017

19290-19295

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Regulation of p53--insights into a complex process

1 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2984141

Structural basis for subversion of cellular control mechanisms by the adenoviral E1A oncoprotein

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2984141

Unlimited multistability in multisite phosphorylation systems

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2984141

6 July 2018

Modes of p53 regulation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2984141

Blinded by the Light: The Growing Complexity of p53

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2984141

Regulation by phosphorylation of the relative affinities of the N-terminal transactivation domains of p53 for p300 domains and Mdm2

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2984141

Cooperative regulation of p53 by modulation of ternary complex formation with CBP/p300 and HDM2

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2984141

Mapping the interactions of the p53 transactivation domain with the KIX domain of CBP

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2984141

Structural basis for recruitment of CBP/p300 coactivators by STAT1 and STAT2 transactivation domains

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2984141

Fundamental aspects of protein-protein association kinetics

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2984141

Two distinct motifs within the p53 transactivation domain bind to the Taz2 domain of p300 and are differentially affected by phosphorylation

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2984141

A complex barcode underlies the heterogeneous response of p53 to stress

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2984141

Acetylation is indispensable for p53 activation

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2984141

Phosphorylation of Thr18 and Ser20 of p53 in Ad-p53-induced apoptosis

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2984141

How important are post-translational modifications in p53 for selectivity in target-gene transcription and tumour suppression?

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2984141

Polyelectrostatic interactions of disordered ligands suggest a physical basis for ultrasensitivity

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2984141

Four domains of p300 each bind tightly to a sequence spanning both transactivation subdomains of p53

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2984141

Graded regulation of the Kv2.1 potassium channel by variable phosphorylation.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2984141

Ser18 and 23 phosphorylation is required for p53-dependent apoptosis and tumor suppression

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2984141

Dissecting p53 tumor suppressor function in vivo through the analysis of genetically modified mice

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2984141

Conditional knockout mice reveal distinct functions for the global transcriptional coactivators CBP and p300 in T-cell development

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2984141

Single-stranded DNA mimicry in the p53 transactivation domain interaction with replication protein A

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2984141

Variable control of Ets-1 DNA binding by multiple phosphates in an unstructured region

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2984141

The role of p53 in hypoxia-induced apoptosis

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2984141

Multisite protein modification and intramolecular signaling

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2984141

Post-translational modification of p53 in tumorigenesis

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2984141

Phosphorylation of p53 on key serines is dispensable for transcriptional activation and apoptosis

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2984141

p300 relieves p53-evoked transcriptional repression of hypoxia-inducible factor-1 (HIF-1).

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2984141

The importance of intrinsic disorder for protein phosphorylation

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2984141

Interaction of the TAZ1 domain of the CREB-binding protein with the activation domain of CITED2: regulation by competition between intrinsically unstructured ligands for non-identical binding sites

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2984141

The N-terminal domain of p53 is natively unfolded.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2984141

Polyubiquitination of p53 by a ubiquitin ligase activity of p300.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2984141

Multisite phosphorylation provides sophisticated regulation of transcription factors

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2984141

Molecular mechanism of the interaction between MDM2 and p53.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2984141

Post-translational modifications and activation of p53 by genotoxic stresses

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2984141

Inhibition of p53-dependent transcription by BOX-I phospho-peptide mimetics that bind to p300.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2984141

HIF-1 and human disease: one highly involved factor

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2984141

Phosphorylation of human p53 on Thr-55.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2984141

Analysis of multisite phosphorylation of the p53 tumor-suppressor protein by tryptic phosphopeptide mapping

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2984141

CBP/p300 in cell growth, transformation, and development

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2984141

Damage-mediated phosphorylation of human p53 threonine 18 through a cascade mediated by a casein 1-like kinase. Effect on Mdm2 binding

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2984141

Serine15 phosphorylation stimulates p53 transactivation but does not directly influence interaction with HDM2.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2984141

Transcriptional cross talk between NF-kappaB and p53.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2984141

CREB-binding protein is a nuclear integrator of nuclear factor-kappaB and p53 signaling

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2984141

Structure of the MDM2 oncoprotein bound to the p53 tumor suppressor transactivation domain

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2984141

Binding of p53-derived ligands to MDM2 induces a variety of long range conformational changes.

6 July 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1013078107

p53 Antiproliferative function is enhanced by aspartate substitution at threonine 18 and serine 20.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1013078107

Mdm-2 binding and TAF(II)31 recruitment is regulated by hydrogen bond disruption between the p53 residues Thr18 and Asp21.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1013078107

Fly-casting in protein-DNA binding: frustration between protein folding and electrostatics facilitates target recognition

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1013078107

p53-dependent transcription can exhibit both on/off and graded response after genotoxic stress

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1013078107

Latent and active p53 are identical in conformation

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1013078107

p53 inhibits hypoxia-inducible factor-stimulated transcription

21 January 2018

1 reference

12 December 2020

Phosphorylation of p53 serine 15 increases interaction with CBP

1 reference

12 December 2020

Structure of the Tfb1/p53 complex: Insights into the interaction between the p62/Tfb1 subunit of TFIIH and the activation domain of p53

1 reference

12 December 2020

Tuning bulk electrostatics to regulate protein function

1 reference

12 December 2020

Differential recognition of phosphorylated transactivation domains of p53 by different p300 domains

1 reference

12 December 2020

Identifiers

DOI

10.1073/PNAS.1013078107

1 reference

1 August 2017

0 references

1 reference

1 August 2017

1 reference

PubMed ID

20962272