Single-cell genome sequencing: current state of the science (Q34045945)

30 July 2017

Single-cell genome sequencing: current state of the science (English)

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30 July 2017

whole genome sequencing

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1

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30 July 2017

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Stephen R Quake

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30 July 2017

2

Winston Koh

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30 July 2017

25 January 2016

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30 July 2017

Nature Reviews Genetics

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30 July 2017

17

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30 July 2017

175-188

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30 July 2017

3

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https://scigraph.springernature.com/pub.10.1038/nrg.2015.16

30 July 2017

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cites work

STUDIES ON THE CHEMICAL NATURE OF THE SUBSTANCE INDUCING TRANSFORMATION OF PNEUMOCOCCAL TYPES: INDUCTION OF TRANSFORMATION BY A DESOXYRIBONUCLEIC ACID FRACTION ISOLATED FROM PNEUMOCOCCUS TYPE III

1 reference

https://api.crossref.org/works/10.1038%2FNRG.2015.16

McKusick's Online Mendelian Inheritance in Man (OMIM)

21 January 2018

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https://api.crossref.org/works/10.1038%2FNRG.2015.16

Comparative metagenomics of microbial communities

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRG.2015.16

Dissecting biological "dark matter" with single-cell genetic analysis of rare and uncultivated TM7 microbes from the human mouth

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRG.2015.16

Mosaic copy number variation in human neurons

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRG.2015.16

Clonal evolution in breast cancer revealed by single nucleus genome sequencing.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRG.2015.16

Laser capture microdissection

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRG.2015.16

Cancer genomics: one cell at a time

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRG.2015.16

CLONAL GROWTH OF MAMMALIAN CELLS IN A CHEMICALLY DEFINED, SYNTHETIC MEDIUM

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRG.2015.16

Genome-wide detection of single-nucleotide and copy-number variations of a single human cell

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRG.2015.16

Massively parallel polymerase cloning and genome sequencing of single cells using nanoliter microwells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRG.2015.16

Optofluidic cell selection from complex microbial communities for single-genome analysis

21 January 2018

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https://api.crossref.org/works/10.1038%2FNRG.2015.16

Tumour evolution inferred by single-cell sequencing

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRG.2015.16

SNES: single nucleus exome sequencing

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRG.2015.16

Obtaining genomes from uncultivated environmental microorganisms using FACS-based single-cell genomics

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRG.2015.16

High-throughput microfluidic single-cell RT-qPCR

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRG.2015.16

A programmable droplet-based microfluidic device applied to multiparameter analysis of single microbes and microbial communities

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRG.2015.16

Highly Parallel Genome-wide Expression Profiling of Individual Cells Using Nanoliter Droplets

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRG.2015.16

The future is now: single-cell genomics of bacteria and archaea

21 January 2018

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https://api.crossref.org/works/10.1038%2FNRG.2015.16

Single-cell sequencing-based technologies will revolutionize whole-organism science

21 January 2018

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https://api.crossref.org/works/10.1038%2FNRG.2015.16

Fluorescence in situ hybridization with Alu and L1 polymerase chain reaction probes for rapid characterization of human chromosomes in hybrid cell lines

21 January 2018

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https://api.crossref.org/works/10.1038%2FNRG.2015.16

Ligation-anchored PCR: a simple amplification technique with single-sided specificity

21 January 2018

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https://api.crossref.org/works/10.1038%2FNRG.2015.16

Whole genome amplification from a single cell: implications for genetic analysis

21 January 2018

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https://api.crossref.org/works/10.1038%2FNRG.2015.16

Rapid amplification of plasmid and phage DNA using Phi 29 DNA polymerase and multiply-primed rolling circle amplification

21 January 2018

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https://api.crossref.org/works/10.1038%2FNRG.2015.16

A quantitative comparison of single-cell whole genome amplification methods

21 January 2018

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https://api.crossref.org/works/10.1038%2FNRG.2015.16

Mechanism of chimera formation during the Multiple Displacement Amplification reaction

21 January 2018

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https://api.crossref.org/works/10.1038%2FNRG.2015.16

Nanoliter reactors improve multiple displacement amplification of genomes from single cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRG.2015.16

Sequencing genomes from single cells by polymerase cloning

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRG.2015.16

21 January 2018

Rubicon Genomics, Inc.

1 reference

https://api.crossref.org/works/10.1038%2FNRG.2015.16

Comparison of variations detection between whole-genome amplification methods used in single-cell resequencing

21 January 2018

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https://api.crossref.org/works/10.1038%2FNRG.2015.16

Single-Cell Whole-Genome Amplification and Sequencing: Methodology and Applications

21 January 2018

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https://api.crossref.org/works/10.1038%2FNRG.2015.16

Digital MDA for enumeration of total nucleic acid contamination

21 January 2018

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https://api.crossref.org/works/10.1038%2FNRG.2015.16

Microfluidic whole genome amplification device for single cell sequencing

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRG.2015.16

Monodisperse Picoliter Droplets for Low-Bias and Contamination-Free Reactions in Single-Cell Whole Genome Amplification

21 January 2018

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https://api.crossref.org/works/10.1038%2FNRG.2015.16

Uniform and accurate single-cell sequencing based on emulsion whole-genome amplification

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRG.2015.16

Dissecting the clonal origins of childhood acute lymphoblastic leukemia by single-cell genomics

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRG.2015.16

Clonal architecture of secondary acute myeloid leukemia defined by single-cell sequencing

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRG.2015.16

Calibrating genomic and allelic coverage bias in single-cell sequencing

21 January 2018

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https://api.crossref.org/works/10.1038%2FNRG.2015.16

Modeling genome coverage in single-cell sequencing

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRG.2015.16

BayesHammer: Bayesian clustering for error correction in single-cell sequencing

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRG.2015.16

Genome-wide copy number analysis of single cells.

21 January 2018

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https://api.crossref.org/works/10.1038%2FNRG.2015.16

A single cell level based method for copy number variation analysis by low coverage massively parallel sequencing

21 January 2018

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https://api.crossref.org/works/10.1038%2FNRG.2015.16

Single-cell copy number variation detection.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRG.2015.16

SPAdes: a new genome assembly algorithm and its applications to single-cell sequencing

21 January 2018

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https://api.crossref.org/works/10.1038%2FNRG.2015.16

IDBA-UD: a de novo assembler for single-cell and metagenomic sequencing data with highly uneven depth

21 January 2018

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https://api.crossref.org/works/10.1038%2FNRG.2015.16

Cluster analysis and display of genome-wide expression patterns

21 January 2018

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https://api.crossref.org/works/10.1038%2FNRG.2015.16

Accurate whole human genome sequencing using reversible terminator chemistry

21 January 2018

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https://api.crossref.org/works/10.1038%2FNRG.2015.16

Using single cell sequencing data to model the evolutionary history of a tumor

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRG.2015.16

Molecular phylogenetics: principles and practice

21 January 2018

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https://api.crossref.org/works/10.1038%2FNRG.2015.16

Targeted access to the genomes of low-abundance organisms in complex microbial communities.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRG.2015.16

Partial genome assembly for a candidate division OP11 single cell from an anoxic spring (Zodletone Spring, Oklahoma).

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRG.2015.16

UGA is an additional glycine codon in uncultured SR1 bacteria from the human microbiota

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRG.2015.16

Candidate phylum TM6 genome recovered from a hospital sink biofilm provides genomic insights into this uncultivated phylum

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRG.2015.16

Single-cell and metagenomic analyses indicate a fermentative and saccharolytic lifestyle for members of the OP9 lineage

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRG.2015.16

Insights into the phylogeny and coding potential of microbial dark matter

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRG.2015.16

CheckM: assessing the quality of microbial genomes recovered from isolates, single cells, and metagenomes

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRG.2015.16

ProDeGe: a computational protocol for fully automated decontamination of genomes

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRG.2015.16

Nearly finished genomes produced using gel microdroplet culturing reveal substantial intraspecies genomic diversity within the human microbiome

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRG.2015.16

One bacterial cell, one complete genome

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRG.2015.16

Efficient de novo assembly of single-cell bacterial genomes from short-read data sets

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRG.2015.16

Metagenome, metatranscriptome and single-cell sequencing reveal microbial response to Deepwater Horizon oil spill

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRG.2015.16

Recent advances in genomic DNA sequencing of microbial species from single cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRG.2015.16

Probing individual environmental bacteria for viruses by using microfluidic digital PCR.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRG.2015.16

Ecology and evolution of viruses infecting uncultivated SUP05 bacteria as revealed by single-cell- and meta-genomics

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRG.2015.16

Viral dark matter and virus-host interactions resolved from publicly available microbial genomes

21 January 2018

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https://api.crossref.org/works/10.1038%2FNRG.2015.16

VirSorter: mining viral signal from microbial genomic data

21 January 2018

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https://api.crossref.org/works/10.1038%2FNRG.2015.16

Single-cell genomics reveals organismal interactions in uncultivated marine protists.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRG.2015.16

Structure, function and diversity of the healthy human microbiome

21 January 2018

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https://api.crossref.org/works/10.1038%2FNRG.2015.16

Unveiling in situ interactions between marine protists and bacteria through single cell sequencing

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRG.2015.16

Mosaicism in human skin. Understanding the patterns and mechanisms

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRG.2015.16

Activating mutations of the stimulatory G protein in the McCune-Albright syndrome

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRG.2015.16

Postzygotic HRAS and KRAS mutations cause nevus sebaceous and Schimmelpenning syndrome.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRG.2015.16

A mosaic activating mutation in AKT1 associated with the Proteus syndrome

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRG.2015.16

Mosaic overgrowth with fibroadipose hyperplasia is caused by somatic activating mutations in PIK3CA

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRG.2015.16

Mechanisms of mosaicism, chimerism and uniparental disomy identified by single nucleotide polymorphism array analysis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRG.2015.16

An estimation of the number of cells in the human body

21 January 2018

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https://api.crossref.org/works/10.1038%2FNRG.2015.16

Genome sequencing of normal cells reveals developmental lineages and mutational processes

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRG.2015.16

Genome-wide single-cell analysis of recombination activity and de novo mutation rates in human sperm

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRG.2015.16

Probing meiotic recombination and aneuploidy of single sperm cells by whole-genome sequencing

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRG.2015.16

Genome analyses of single human oocytes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRG.2015.16

Single-cell, genome-wide sequencing identifies clonal somatic copy-number variation in the human brain

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRG.2015.16

Single cell sequencing reveals low levels of aneuploidy across mammalian tissues

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRG.2015.16

Somatic mutation in single human neurons tracks developmental and transcriptional history

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRG.2015.16

Pregnancies from biopsied human preimplantation embryos sexed by Y-specific DNA amplification

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRG.2015.16

Polar body array CGH for prediction of the status of the corresponding oocyte. Part I: clinical results

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRG.2015.16

The Cancer Genome Atlas Pan-Cancer analysis project

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRG.2015.16

Clonal evolution in relapsed acute myeloid leukaemia revealed by whole-genome sequencing

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRG.2015.16

Intratumor Heterogeneity and Branched Evolution Revealed by Multiregion Sequencing

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRG.2015.16

Single-cell exome sequencing and monoclonal evolution of a JAK2-negative myeloproliferative neoplasm

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRG.2015.16

Single-cell exome sequencing reveals single-nucleotide mutation characteristics of a kidney tumor

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRG.2015.16

Single-cell sequencing analysis characterizes common and cell-lineage-specific mutations in a muscle-invasive bladder cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRG.2015.16

Discovery of biclonal origin and a novel oncogene SLC12A5 in colon cancer by single-cell sequencing

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRG.2015.16

Reproducible copy number variation patterns among single circulating tumor cells of lung cancer patients

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRG.2015.16

Whole-exome sequencing of circulating tumor cells provides a window into metastatic prostate cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRG.2015.16

Single-cell mutational profiling and clonal phylogeny in cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRG.2015.16

RAG-mediated recombination is the predominant driver of oncogenic rearrangement in ETV6-RUNX1 acute lymphoblastic leukemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRG.2015.16

Clonal evolution of preleukemic hematopoietic stem cells precedes human acute myeloid leukemia.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRG.2015.16

On-chip separation and analysis of RNA and DNA from single cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRG.2015.16

G&T-seq: parallel sequencing of single-cell genomes and transcriptomes

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRG.2015.16

Integrated genome and transcriptome sequencing of the same cell

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRG.2015.16

Quantitative PCR analysis of DNA, RNAs, and proteins in the same single cell

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRG.2015.16

Highly multiplexed subcellular RNA sequencing in situ

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRG.2015.16

Spatial reconstruction of single-cell gene expression data

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRG.2015.16

High-throughput spatial mapping of single-cell RNA-seq data to tissue of origin

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRG.2015.16

Evolution and dynamics of pancreatic cancer progression

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRG.2015.16

Degenerate oligonucleotide-primed PCR: General amplification of target DNA by a single degenerate primer

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRG.2015.16

Human intersex with chromosome mosaicism of type XY/XO. Report of a case

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRG.2015.16

Somatic mosaicism for copy number variation in differentiated human tissues

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRG.2015.16

First births after preimplantation genetic diagnosis of structural chromosome abnormalities using comparative genomic hybridization and microarray analysis

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRG.2015.16

Ramification amplification: a novel isothermal DNA amplification method

31 March 2020

1 reference

12 December 2020

Rates of spontaneous mutation

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12 December 2020

Reconstructing each cell's genome within complex microbial communities-dream or reality?

1 reference

12 December 2020

The Cell Theory, Past and Present

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12 December 2020

DNA recovery from soils of diverse composition.

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12 December 2020

Identifiers

DOI

10.1038/NRG.2015.16

1 reference

PubMed ID

26806412

Dimensions Publication ID

30 July 2017

0 references

1 reference

PubMed ID

26806412