Animal models of amyloid-beta-related pathologies in Alzheimer's disease (Q34097190)

31 July 2017

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title

Animal models of amyloid-beta-related pathologies in Alzheimer's disease (English)

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31 July 2017

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5

Lars Lannfelt

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31 July 2017

Ola Philipson

1

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31 July 2017

Anna Lord

2

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31 July 2017

Astrid Gumucio

3

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31 July 2017

Paul O'Callaghan

4

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31 July 2017

Lars N G Nilsson

6

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31 July 2017

language of work or name

English

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publication date

3 February 2010

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31 July 2017

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31 July 2017

277

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31 July 2017

6

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31 July 2017

1389-1409

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Alzheimer's disease: Initial report of the purification and characterization of a novel cerebrovascular amyloid protein

31 July 2017

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2010.07564.X

The precursor of Alzheimer's disease amyloid A4 protein resembles a cell-surface receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2010.07564.X

Segregation of a missense mutation in the amyloid precursor protein gene with familial Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2010.07564.X

Mutation of the beta-amyloid precursor protein in familial Alzheimer's disease increases beta-protein production

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2010.07564.X

Mutant genes in familial Alzheimer's disease and transgenic models

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2010.07564.X

Dominant and differential deposition of distinct beta-amyloid peptide species, A beta N3(pE), in senile plaques.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2010.07564.X

APP locus duplication causes autosomal dominant early-onset Alzheimer disease with cerebral amyloid angiopathy

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2010.07564.X

Presenile dementia and Alzheimer's disease in mongolism.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2010.07564.X

Gene dose of apolipoprotein E type 4 allele and the risk of Alzheimer's disease in late onset families

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2010.07564.X

Apolipoprotein E: high-avidity binding to beta-amyloid and increased frequency of type 4 allele in late-onset familial Alzheimer disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2010.07564.X

The role of apolipoprotein E in Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2010.07564.X

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2010.07564.X

On neurodegenerative diseases, models, and treatment strategies: lessons learned and lessons forgotten a generation following the cholinergic hypothesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2010.07564.X

Aging renders the brain vulnerable to amyloid beta-protein neurotoxicity

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2010.07564.X

Chronic neuroinflammation in rats reproduces components of the neurobiology of Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2010.07564.X

Senescence-accelerated mouse (SAM) with special references to neurodegeneration models, SAMP8 and SAMP10 mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2010.07564.X

A mouse model for Down syndrome exhibits learning and behaviour deficits.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2010.07564.X

Alzheimer's disease abeta vaccine reduces central nervous system abeta levels in a non-human primate, the Caribbean vervet

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2010.07564.X

Microcebus murinus: a useful primate model for human cerebral aging and Alzheimer's disease?

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2010.07564.X

Cerebral amyloid-beta protein accumulation with aging in cotton-top tamarins: a model of early Alzheimer's disease?

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2010.07564.X

Alzheimer's Abeta vaccination of rhesus monkeys (Macaca mulatta).

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2010.07564.X

Tauopathy with paired helical filaments in an aged chimpanzee

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2010.07564.X

Age-associated inclusions in normal and transgenic mouse brain.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2010.07564.X

Accumulation of beta-amyloid fibrils in pancreas of transgenic mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2010.07564.X

Amyloid-beta deposition in skeletal muscle of transgenic mice: possible model of inclusion body myopathy

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2010.07564.X

Introduction and expression of the 400 kilobase amyloid precursor protein gene in transgenic mice [corrected]

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2010.07564.X

Abeta is targeted to the vasculature in a mouse model of hereditary cerebral hemorrhage with amyloidosis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2010.07564.X

Abeta42 is essential for parenchymal and vascular amyloid deposition in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2010.07564.X

A mutation in the amyloid precursor protein associated with hereditary Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2010.07564.X

Spectrum of amyloid β-protein immunoreactivity in hereditary Alzheimer disease with a guanine to thymine missence change at position 1924 of the APP gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2010.07564.X

Alzheimer-type neuropathology in transgenic mice overexpressing V717F β-amyloid precursor protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2010.07564.X

Amyloid precursor protein processing and A beta42 deposition in a transgenic mouse model of Alzheimer disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2010.07564.X

Neurofibrillary pathology in transgenic mice overexpressing V717F beta-amyloid precursor protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2010.07564.X

Unusual spectral energy distribution of a galaxy previously reported to be at redshift 6.68.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2010.07564.X

Dentate gyrus volume is reduced before onset of plaque formation in PDAPP mice: a magnetic resonance microscopy and stereologic analysis

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2010.07564.X

Early phenotypic changes in transgenic mice that overexpress different mutants of amyloid precursor protein in brain

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2010.07564.X

Prominent cerebral amyloid angiopathy in transgenic mice overexpressing the london mutant of human APP in neurons.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2010.07564.X

Clinical comparison of Alzheimer's disease in pedigrees with the codon 717 Val→Ile mutation in the amyloid precursor protein gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2010.07564.X

A pathogenic mutation for probable Alzheimer's disease in the APP gene at the N-terminus of beta-amyloid

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2010.07564.X

Release of excess amyloid beta protein from a mutant amyloid beta protein precursor.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2010.07564.X

Beta-secretase cleavage of Alzheimer's amyloid precursor protein by the transmembrane aspartic protease BACE

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2010.07564.X

Correlative Memory Deficits, Abeta Elevation, and Amyloid Plaques in Transgenic Mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2010.07564.X

The Swedish mutation causes early-onset Alzheimer's disease by beta-secretase cleavage within the secretory pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2010.07564.X

Endocytosis is required for synaptic activity-dependent release of amyloid-beta in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2010.07564.X

Chimeric prion protein expression in cultured cells and transgenic mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2010.07564.X

Augmented senile plaque load in aged female beta-amyloid precursor protein-transgenic mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2010.07564.X

Familial Alzheimer's disease-linked presenilin 1 variants elevate Abeta1-42/1-40 ratio in vitro and in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2010.07564.X

A vector for expressing foreign genes in the brains and hearts of transgenic mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2010.07564.X

Enhanced amyloidogenic processing of the beta-amyloid precursor protein in gene-targeted mice bearing the Swedish familial Alzheimer's disease mutations and a "humanized" Abeta sequence.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2010.07564.X

FAD mutant PS-1 gene-targeted mice: increased A beta 42 and A beta deposition without APP overproduction

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2010.07564.X

Alterations in beta-amyloid production and deposition in brain regions of two transgenic models.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2010.07564.X

Amyloid production and deposition in mutant amyloid precursor protein and presenilin-1 yeast artificial chromosome transgenic mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2010.07564.X

Two amyloid precursor protein transgenic mouse models with Alzheimer disease-like pathology

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2010.07564.X

Neuronal overexpression of mutant amyloid precursor protein results in prominent deposition of cerebrovascular amyloid

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2010.07564.X

Age-dependent cognitive decline in the APP23 model precedes amyloid deposition.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2010.07564.X

Early-onset amyloid deposition and cognitive deficits in transgenic mice expressing a double mutant form of amyloid precursor protein 695.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2010.07564.X

Abeta40 inhibits amyloid deposition in vivo.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2010.07564.X

Persistent amyloidosis following suppression of Abeta production in a transgenic model of Alzheimer disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2010.07564.X

Mutation of the Alzheimer's disease amyloid gene in hereditary cerebral hemorrhage, Dutch type.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2010.07564.X

Novel amyloid precursor protein mutation in an Iowa family with dementia and severe cerebral amyloid angiopathy

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2010.07564.X

Early-onset and robust cerebral microvascular accumulation of amyloid beta-protein in transgenic mice expressing low levels of a vasculotropic Dutch/Iowa mutant form of amyloid beta-protein precursor

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2010.07564.X

Early-onset subicular microvascular amyloid and neuroinflammation correlate with behavioral deficits in vasculotropic mutant amyloid beta-protein precursor transgenic mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2010.07564.X

Presenile dementia and cerebral haemorrhage linked to a mutation at codon 692 of the beta-amyloid precursor protein gene.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2010.07564.X

The 'Arctic' APP mutation (E693G) causes Alzheimer's disease by enhanced Abeta protofibril formation

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2010.07564.X

Constitutive and regulated alpha-secretase cleavage of Alzheimer's amyloid precursor protein by a disintegrin metalloprotease

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2010.07564.X

Behavioral disturbances without amyloid deposits in mice overexpressing human amyloid precursor protein with Flemish (A692G) or Dutch (E693Q) mutation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2010.07564.X

Clinical and neuropathological features of the arctic APP gene mutation causing early-onset Alzheimer disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2010.07564.X

The Arctic mutation interferes with processing of the amyloid precursor protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2010.07564.X

The Arctic Alzheimer mutation favors intracellular amyloid-beta production by making amyloid precursor protein less available to alpha-secretase

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2010.07564.X

Intracellular Abeta and cognitive deficits precede beta-amyloid deposition in transgenic arcAbeta mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2010.07564.X

The Arctic Alzheimer mutation facilitates early intraneuronal Abeta aggregation and senile plaque formation in transgenic mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2010.07564.X

Amyloid-beta protofibril levels correlate with spatial learning in Arctic Alzheimer's disease transgenic mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2010.07564.X

Aggressive amyloidosis in mice expressing human amyloid peptides with the Arctic mutation

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2010.07564.X

Increased amyloid-beta42(43) in brains of mice expressing mutant presenilin 1

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2010.07564.X

Accelerated amyloid deposition in the brains of transgenic mice coexpressing mutant presenilin 1 and amyloid precursor proteins.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2010.07564.X

Accelerated Alzheimer-type phenotype in transgenic mice carrying both mutant amyloid precursor protein and presenilin 1 transgenes

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2010.07564.X

Enhanced neurofibrillary degeneration in transgenic mice expressing mutant tau and APP.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2010.07564.X

Characterisation of cytoskeletal abnormalities in mice transgenic for wild-type human tau and familial Alzheimer's disease mutants of APP and presenilin-1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2010.07564.X

beta-amyloid peptides enhance alpha-synuclein accumulation and neuronal deficits in a transgenic mouse model linking Alzheimer's disease and Parkinson's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2010.07564.X

Co-expression of multiple transgenes in mouse CNS: a comparison of strategies.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2010.07564.X

Triple-transgenic model of Alzheimer's disease with plaques and tangles: intracellular Abeta and synaptic dysfunction

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2010.07564.X

Detailed immunohistochemical characterization of temporal and spatial progression of Alzheimer's disease-related pathologies in male triple-transgenic mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2010.07564.X

Reduction of soluble Abeta and tau, but not soluble Abeta alone, ameliorates cognitive decline in transgenic mice with plaques and tangles

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2010.07564.X

Abeta immunotherapy leads to clearance of early, but not late, hyperphosphorylated tau aggregates via the proteasome

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2010.07564.X

Intraneuronal beta-amyloid aggregates, neurodegeneration, and neuron loss in transgenic mice with five familial Alzheimer's disease mutations: potential factors in amyloid plaque formation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2010.07564.X

BACE1 gene deletion prevents neuron loss and memory deficits in 5XFAD APP/PS1 transgenic mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2010.07564.X

Massive CA1/2 neuronal loss with intraneuronal and N-terminal truncated Abeta42 accumulation in a novel Alzheimer transgenic model

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2010.07564.X

Plaque-associated disruption of CSF and plasma amyloid-beta (Abeta) equilibrium in a mouse model of Alzheimer's disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2010.07564.X

Structural and functional disruption of vascular smooth muscle cells in a transgenic mouse model of amyloid angiopathy

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2010.07564.X

Computer-assisted three-dimensional image analysis of cerebral amyloid angiopathy.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2010.07564.X

Exogenous induction of cerebral beta-amyloidogenesis is governed by agent and host

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2010.07564.X

Rapid appearance and local toxicity of amyloid-beta plaques in a mouse model of Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2010.07564.X

Characterizing the appearance and growth of amyloid plaques in APP/PS1 mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2010.07564.X

Plaque-induced neurite abnormalities: implications for disruption of neural networks in Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2010.07564.X

Dendritic spine abnormalities in amyloid precursor protein transgenic mice demonstrated by gene transfer and intravital multiphoton microscopy

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2010.07564.X

Intraneuronal pyroglutamate-Abeta 3-42 triggers neurodegeneration and lethal neurological deficits in a transgenic mouse model

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2010.07564.X

Lack of apolipoprotein E dramatically reduces amyloid beta-peptide deposition.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2010.07564.X

Human and murine ApoE markedly alters A beta metabolism before and after plaque formation in a mouse model of Alzheimer's disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2010.07564.X

Increased amyloid beta-peptide deposition in cerebral cortex as a consequence of apolipoprotein E genotype in late-onset Alzheimer disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2010.07564.X

Expression of human apolipoprotein E reduces amyloid-beta deposition in a mouse model of Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2010.07564.X

Clusterin promotes amyloid plaque formation and is critical for neuritic toxicity in a mouse model of Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2010.07564.X

ApoE and clusterin cooperatively suppress Abeta levels and deposition: evidence that ApoE regulates extracellular Abeta metabolism in vivo.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2010.07564.X

Immunochemical identification of the serine protease inhibitor alpha 1-antichymotrypsin in the brain amyloid deposits of Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2010.07564.X

Cognitive impairment in PDAPP mice depends on ApoE and ACT-catalyzed amyloid formation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2010.07564.X

Astroglial expression of human alpha(1)-antichymotrypsin enhances alzheimer-like pathology in amyloid protein precursor transgenic mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2010.07564.X

TGF-beta1 promotes microglial amyloid-beta clearance and reduces plaque burden in transgenic mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2010.07564.X

Amyloidogenic role of cytokine TGF-beta1 in transgenic mice and in Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2010.07564.X

Bone marrow-derived microglia play a critical role in restricting senile plaque formation in Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2010.07564.X

Invasion of hematopoietic cells into the brain of amyloid precursor protein transgenic mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2010.07564.X

Overexpression of monocyte chemotactic protein-1/CCL2 in beta-amyloid precursor protein transgenic mice show accelerated diffuse beta-amyloid deposition

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2010.07564.X

Ccr2 deficiency impairs microglial accumulation and accelerates progression of Alzheimer-like disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2010.07564.X

Contribution by synaptic zinc to the gender-disparate plaque formation in human Swedish mutant APP transgenic mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2010.07564.X

Estrogen decreases zinc transporter 3 expression and synaptic vesicle zinc levels in mouse brain

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2010.07564.X

Mapping genetic modulators of amyloid plaque deposition in TgCRND8 transgenic mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2010.07564.X

Generation of Abeta38 and Abeta42 is independently and differentially affected by familial Alzheimer disease-associated presenilin mutations and gamma-secretase modulation

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2010.07564.X

A highly insoluble state of Abeta similar to that of Alzheimer's disease brain is found in Arctic APP transgenic mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2010.07564.X

A beta peptide immunization reduces behavioural impairment and plaques in a model of Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2010.07564.X

A beta peptide vaccination prevents memory loss in an animal model of Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2010.07564.X

Immunization with amyloid-beta attenuates Alzheimer-disease-like pathology in the PDAPP mouse

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2010.07564.X

Subacute meningoencephalitis in a subset of patients with AD after Abeta42 immunization

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2010.07564.X

Abeta species removal after abeta42 immunization.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2010.07564.X

Peripherally administered antibodies against amyloid beta-peptide enter the central nervous system and reduce pathology in a mouse model of Alzheimer disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2010.07564.X

The effect of age on the cognate function of CD4+ T cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2010.07564.X

Peripheral anti-A beta antibody alters CNS and plasma A beta clearance and decreases brain A beta burden in a mouse model of Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2010.07564.X

An amyloid-beta protofibril-selective antibody prevents amyloid formation in a mouse model of Alzheimer's disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2010.07564.X

Safety, tolerability, and effects on plasma and cerebrospinal fluid amyloid-beta after inhibition of gamma-secretase

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2010.07564.X

Development of semagacestat (LY450139), a functional gamma-secretase inhibitor, for the treatment of Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2010.07564.X

Control of peripheral nerve myelination by the beta-secretase BACE1

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2010.07564.X

Skeletal and CNS defects in Presenilin-1-deficient mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2010.07564.X

Behavioral phenotyping strategies for mutant mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2010.07564.X

Use of multimetric statistical analysis to characterize and discriminate between the performance of four Alzheimer's transgenic mouse lines differing in Abeta deposition

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2010.07564.X

Place navigation impaired in rats with hippocampal lesions

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2010.07564.X

The hippocampus as a spatial map. Preliminary evidence from unit activity in the freely-moving rat

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2010.07564.X

Progressive, age-related behavioral impairments in transgenic mice carrying both mutant amyloid precursor protein and presenilin-1 transgenes

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2010.07564.X

A comparison of wild-caught wood mice and bank voles in the Intellicage: assessing exploration, daily activity patterns and place learning paradigms

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2010.07564.X

Behavioral phenotyping of a murine model of Alzheimer's disease in a seminaturalistic environment using RFID tracking.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2010.07564.X

Towards a transgenic model of Huntington's disease in a non-human primate

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2010.07564.X

The normal equilibrium between CSF and plasma amyloid beta levels is disrupted in Alzheimer's disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2010.07564.X

Neuron loss in APP transgenic mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2010.07564.X

10.1111/J.1742-4658.2010.07564.X

21 January 2018

Identifiers

DOI

1 reference

31 July 2017

1 reference