Protein tyrosine phosphatase 1B inhibitors: a molecular level legitimate approach for the management of diabetes mellitus (Q34135843)

31 July 2017

Protein tyrosine phosphatase 1B inhibitors: a molecular level legitimate approach for the management of diabetes mellitus (English)

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31 July 2017

Suresh Thareja

1

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31 July 2017

Saurabh Aggarwal

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2

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31 July 2017

T R Bhardwaj

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3

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31 July 2017

Manoj Kumar

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4

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31 July 2017

2 September 2010

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Medicinal Research Reviews

31 July 2017

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31 July 2017

32

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31 July 2017

3

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31 July 2017

459-517

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A new orally active antidiabetic vanadyl complex--bis(alpha-furancarboxylato)oxovanadium(IV).

31 July 2017

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Global and societal implications of the diabetes epidemic

21 January 2018

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A new concept: the use of vanadium complexes in the treatment of diabetes mellitus

21 January 2018

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Aldose reductase inhibitors and diabetic complications

21 January 2018

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Redefining type 2 diabetes: 'diabesity' or 'obesity dependent diabetes mellitus'?

21 January 2018

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Globalization, coca-colonization and the chronic disease epidemic: can the Doomsday scenario be averted?

21 January 2018

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Global burden of diabetes, 1995-2025: prevalence, numerical estimates, and projections

21 January 2018

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Ameliorating effect of FK614, a novel nonthiazolidinedione peroxisome proliferator-activated receptor gamma agonist, on insulin resistance in Zucker fatty rat.

21 January 2018

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Redistribution of substrates to adipose tissue promotes obesity in mice with selective insulin resistance in muscle

21 January 2018

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Antidiabetic and hypolipidemic potential of DRF 2519--a dual activator of PPAR-alpha and PPAR-gamma

21 January 2018

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Banting lecture 1988. Role of insulin resistance in human disease

21 January 2018

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Stress-induced hyperglycemia

21 January 2018

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Antihyperglycemic activity of 2-methyl-3,4,5-triaryl-1H-pyrroles in SLM and STZ models

21 January 2018

1 reference

5,6-Diarylanthranilo-1,3-dinitriles as a new class of antihyperglycemic agents

21 January 2018

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Rosiglitazone in the treatment of type 2 diabetes mellitus: a critical review

21 January 2018

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The thiazolidinediones rosiglitazone and pioglitazone and the risk of coronary heart disease: a retrospective cohort study using a US health insurance database

21 January 2018

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Saxagliptin: a new dipeptidyl peptidase-4 inhibitor for the treatment of type 2 diabetes

21 January 2018

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DPP-4 inhibitor therapy: new directions in the treatment of type 2 diabetes.

21 January 2018

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Biology of incretins: GLP-1 and GIP

21 January 2018

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Glucagon-like peptide-1: the basis of a new class of treatment for type 2 diabetes.

21 January 2018

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The alpha-glucosidase inhibitor miglitol delays the development of diabetes and dysfunctional insulin secretion in pancreatic beta-cells in OLETF rats

21 January 2018

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New drugs for management of diabetes: insulin analogues, inhaled insulin, pramlintide, and novel peptides

21 January 2018

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Selective glycogen synthase kinase 3 inhibitors potentiate insulin activation of glucose transport and utilization in vitro and in vivo

21 January 2018

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Peroxisome proliferator-activated receptor alpha/gamma dual agonists for the treatment of type 2 diabetes

21 January 2018

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Glucose transporter and Na+/glucose cotransporter as molecular targets of anti-diabetic drugs

21 January 2018

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Hepatic dysfunction and insulin insensitivity in type 2 diabetes mellitus: a critical target for insulin-sensitizing agents

21 January 2018

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Inhibition of protein tyrosine phosphatase 1B as a potential treatment of diabetes and obesity

21 January 2018

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The transmembrane protein tyrosine phosphatase alpha dephosphorylates the insulin receptor in intact cells

21 January 2018

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Control of vesicle fusion by a tyrosine phosphatase

21 January 2018

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Redox modulation of tyrosine phosphorylation-dependent signal transduction pathways

21 January 2018

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Protein tyrosine phosphatases and their inhibitors

21 January 2018

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Oxidative inactivation of protein tyrosine phosphatase 1B by organic hydroperoxides

21 January 2018

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Signaling--2000 and beyond

21 January 2018

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Targeting the PTPome in human disease

21 January 2018

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Significance of protein tyrosine kinase/protein tyrosine phosphatase balance in the regulation of NF-kappaB signaling in the inflammatory process and aging.

21 January 2018

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Initial sequencing and analysis of the human genome

21 January 2018

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Protein-tyrosine phosphatases: biological function, structural characteristics, and mechanism of catalysis

21 January 2018

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Protein tyrosine phosphatases: prospects for therapeutics

21 January 2018

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PTP1B inhibitors as potential therapeutics in the treatment of type 2 diabetes and obesity

21 January 2018

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Role of protein tyrosine phosphatase-1B in diabetes and obesity

21 January 2018

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Molecular basis for the dephosphorylation of the activation segment of the insulin receptor by protein tyrosine phosphatase 1B

21 January 2018

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The ins and outs of leptin receptor activation

21 January 2018

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Mechanism of protein tyrosine phosphatase 1B-mediated inhibition of leptin signalling

21 January 2018

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Increased insulin sensitivity and obesity resistance in mice lacking the protein tyrosine phosphatase-1B gene

21 January 2018

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Increased energy expenditure, decreased adiposity, and tissue-specific insulin sensitivity in protein-tyrosine phosphatase 1B-deficient mice

21 January 2018

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Protein tyrosine phosphatase 1B reduction regulates adiposity and expression of genes involved in lipogenesis

21 January 2018

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Neuronal PTP1B regulates body weight, adiposity and leptin action.

21 January 2018

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Diet-induced obesity alters AMP kinase activity in hypothalamus and skeletal muscle.

21 January 2018

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Neuronal protein tyrosine phosphatase 1B deficiency results in inhibition of hypothalamic AMPK and isoform-specific activation of AMPK in peripheral tissues

21 January 2018

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Protein tyrosine phosphatase 1B inhibition: opportunities and challenges

21 January 2018

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Protein tyrosine phosphatase-1B in diabetes

21 January 2018

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Protein-tyrosine phosphatase 1B potentiates IRE1 signaling during endoplasmic reticulum stress

21 January 2018

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Liver-specific deletion of protein-tyrosine phosphatase 1B (PTP1B) improves metabolic syndrome and attenuates diet-induced endoplasmic reticulum stress

21 January 2018

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Protein-tyrosine phosphatase 1B expression is induced by inflammation in vivo

21 January 2018

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Protein-tyrosine phosphatase 1B-deficient myocytes show increased insulin sensitivity and protection against tumor necrosis factor-alpha-induced insulin resistance

21 January 2018

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Protein-tyrosine phosphatase 1B is required for HER2/Neu-induced breast cancer.

21 January 2018

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Protein tyrosine phosphatase 1B deficiency or inhibition delays ErbB2-induced mammary tumorigenesis and protects from lung metastasis

21 January 2018

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Activation of Src by protein tyrosine phosphatase 1B Is required for ErbB2 transformation of human breast epithelial cells

21 January 2018

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Inhibition of the protein tyrosine phosphatase PTP1B: potential therapy for obesity, insulin resistance and type-2 diabetes mellitus

21 January 2018

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Protein tyrosine phosphatases: their role in insulin action and potential as drug targets.

21 January 2018

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Orally active insulin mimics: where do we stand now?

21 January 2018

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Protein tyrosine phosphatase 1B interacts with the activated insulin receptor

21 January 2018

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Protein tyrosine phosphatase 1B inhibitors for diabetes

21 January 2018

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PTP1B: from the sidelines to the front lines!

21 January 2018

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Visualization of the cysteinyl-phosphate intermediate of a protein-tyrosine phosphatase by x-ray crystallography

21 January 2018

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A molecular dynamics study of WPD-loop flexibility in PTP1B.

21 January 2018

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Structural basis for inhibition of the protein tyrosine phosphatase 1B by phosphotyrosine peptide mimetics

21 January 2018

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Computational analysis of tyrosine phosphatase inhibitor selectivity for the virulence factors YopH and SptP.

21 January 2018

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Inhibition of protein tyrosine phosphatase-1B with antisense oligonucleotides improves insulin sensitivity and increases adiponectin concentrations in monkeys

21 January 2018

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5-Aryl thiazolidine-2,4-diones as selective PPARgamma agonists

21 January 2018

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Peroxisome proliferator-activated receptors: nuclear control of metabolism

21 January 2018

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An antidiabetic thiazolidinedione is a high affinity ligand for peroxisome proliferator-activated receptor gamma (PPAR gamma)

21 January 2018

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New oral therapies for type 2 diabetes mellitus: The glitazones or insulin sensitizers

21 January 2018

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Rosiglitazone ameliorates abnormal expression and activity of protein tyrosine phosphatase 1B in the skeletal muscle of fat-fed, streptozotocin-treated diabetic rats

21 January 2018

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Improved glucose homeostasis in mice with muscle-specific deletion of protein-tyrosine phosphatase 1B.

21 January 2018

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Structure-based optimization of benzoic acids as inhibitors of protein tyrosine phosphatase 1B and low molecular weight protein tyrosine phosphatase.

21 January 2018

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Thiazolidinedione derivatives as PTP1B inhibitors with antihyperglycemic and antiobesity effects

21 January 2018

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Self-organizing molecular field analysis of 2,4-thiazolidinediones: A 3D-QSAR model for the development of human PTP1B inhibitors

21 January 2018

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5-Arylidene-2-phenylimino-4-thiazolidinones as PTP1B and LMW-PTP inhibitors.

21 January 2018

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Residues distant from the active site influence protein-tyrosine phosphatase 1B inhibitor binding

21 January 2018

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Prodrugs of phosphates and phosphonates

21 January 2018

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Utilization of a peptide lead for the discovery of a novel PTP1B-binding motif

21 January 2018

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The difluoromethylenesulfonic acid group as a monoanionic phosphate surrogate for obtaining PTP1B inhibitors

21 January 2018

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Alpha,alpha-difluoro-beta-ketophosphonates as potent inhibitors of protein tyrosine phosphatase 1B.

21 January 2018

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Discovery and structure-activity relationships of novel sulfonamides as potent PTP1B inhibitors

21 January 2018

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PTP1B inhibitors: synthesis and evaluation of difluoro-methylenephosphonate bioisosteres on a sulfonamide scaffold

21 January 2018

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Structure-based design and discovery of protein tyrosine phosphatase inhibitors incorporating novel isothiazolidinone heterocyclic phosphotyrosine mimetics

21 January 2018

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Isothiazolidinone inhibitors of PTP1B containing imidazoles and imidazolines

21 January 2018

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Identification of a monoacid-Based, cell permeable, selective inhibitor of protein tyrosine phosphatase 1B

21 January 2018

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2-O-carboxymethylpyrogallol derivatives as PTP1B inhibitors with antihyperglycemic activity.

21 January 2018

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3D-QSAR CoMFA and CoMSIA on protein tyrosine phosphatase 1B inhibitors

21 January 2018

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Classification of inhibitors of protein tyrosine phosphatase 1B using molecular structure based descriptors

21 January 2018

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Mechanistic toxicogenomic analysis of WAY-144122 administration in Sprague-Dawley rats

21 January 2018

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Ertiprotafib improves glycemic control and lowers lipids via multiple mechanisms

21 January 2018

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2-(oxalylamino)-benzoic acid is a general, competitive inhibitor of protein-tyrosine phosphatases

21 January 2018

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The Cys(X)5Arg catalytic motif in phosphoester hydrolysis

21 January 2018

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Discovery and SAR of a novel selective and orally bioavailable nonpeptide classical competitive inhibitor class of protein-tyrosine phosphatase 1B.

21 January 2018

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Discovery and Structure−Activity Relationship of Oxalylarylaminobenzoic Acids as Inhibitors of Protein Tyrosine Phosphatase 1B

21 January 2018

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Potent, selective inhibitors of protein tyrosine phosphatase 1B

21 January 2018

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Bicyclic and tricyclic thiophenes as protein tyrosine phosphatase 1B inhibitors

21 January 2018

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Synthesis and PTP1B inhibition of 1,2-naphthoquinone derivatives as potent anti-diabetic agents

21 January 2018

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Discovery of a novel protein tyrosine phosphatase-1B inhibitor, KR61639: potential development as an antihyperglycemic agent

21 January 2018

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Formylchromone derivatives as a novel class of protein tyrosine phosphatase 1B inhibitors

21 January 2018

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Formylchromone derivatives as irreversible and selective inhibitors of human protein tyrosine phosphatase 1B. Kinetic and modeling studies

21 January 2018

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Synthesis and biological activity of a novel class of pyridazine analogues as non-competitive reversible inhibitors of protein tyrosine phosphatase 1B (PTP1B).

21 January 2018

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Mechanism of action of pyridazine analogues on protein tyrosine phosphatase 1B (PTP1B).

21 January 2018

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alpha-bromoacetophenone derivatives as neutral protein tyrosine phosphatase inhibitors: structure-Activity relationship

21 January 2018

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Synthesis of functionalized acetophenones as protein tyrosine phosphatase 1B inhibitors

21 January 2018

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Identification of a novel class of orally active pyrimido[5,4-3][1,2,4]triazine-5,7-diamine-based hypoglycemic agents with protein tyrosine phosphatase inhibitory activity

21 January 2018

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PTP-1B inhibitors: cyclopenta[d][1,2]-oxazine derivatives

21 January 2018

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Fragment screening and assembly: a highly efficient approach to a selective and cell active protein tyrosine phosphatase 1B inhibitor

21 January 2018

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Isoxazole carboxylic acids as protein tyrosine phosphatase 1B (PTP1B) inhibitors

21 January 2018

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Synthesis of triazole-linked beta-C-glycosyl dimers as inhibitors of PTP1B.

21 January 2018

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Synthesis of protein tyrosine phosphatase 1B inhibitors: model validation and docking studies

21 January 2018

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The evolving role of natural products in drug discovery

21 January 2018

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Natural PTP1B inhibitors from Broussonetia papyrifera

21 January 2018

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Effects of berberine on glucose metabolism in vitro

21 January 2018

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Insulin sensitizing and insulinotropic action of berberine from Cortidis rhizoma

21 January 2018

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Berberine stimulates glucose transport through a mechanism distinct from insulin.

21 January 2018

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Docking simulations and in vitro assay unveil potent inhibitory action of papaverine against protein tyrosine phosphatase 1B.

21 January 2018

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Isoprenylated flavonoids from the stem bark of Erythrina abyssinica

21 January 2018

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Flavanones from the stem bark of Erythrina abyssinica

21 January 2018

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Cinnamic acid, from the bark of Cinnamomum cassia, regulates glucose transport via activation of GLUT4 on L6 myotubes in a phosphatidylinositol 3-kinase-independent manner

21 January 2018

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Peptidyl aldehydes as reversible covalent inhibitors of protein tyrosine phosphatases

21 January 2018

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Protein tyrosine phosphatase 1B inhibitors from Morus root bark

21 January 2018

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PTP1B inhibitors from Ardisia japonica

21 January 2018

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Antidiabetic effects of extracts from Psidium guajava

21 January 2018

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Molecular design and biological activities of protein-tyrosine phosphatase inhibitors

21 January 2018

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Hyrtiosal, a PTP1B inhibitor from the marine sponge Hyrtios erectus, shows extensive cellular effects on PI3K/AKT activation, glucose transport, and TGFbeta/Smad2 signaling.

21 January 2018

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Dephostatin, a novel protein tyrosine phosphatase inhibitor produced by Streptomyces. I. Taxonomy,isolation, and characterization.

21 January 2018

1 reference

12 April 2024

https://opencitations.net/index/api/v1/citations/10.7164/ANTIBIOTICS.46.1342

Identifiers

DOI

10.1002/MED.20219

1 reference

31 July 2017

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