The role of IL-23 in the immunopathogenesis of psoriasis (Q34175490)

31 July 2017

title

The role of IL-23 in the immunopathogenesis of psoriasis (English)

1 reference

31 July 2017

1

Paola Di Meglio

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A20948793

3 August 2024

author name string

Frank O. Nestle

series ordinal

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A20948793

3 August 2024

language of work or name

1 reference

24 May 2010

1 reference

full work available at URL

31 July 2017

https://facultyopinions.com/prime/reports/b/2/40/pdf

file format

Portable Document Format

online access status

open access

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A20948793

https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/20948793/pdf/?tool=EBI

3 August 2024

file format

Portable Document Format

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A20948793

https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/20948793/?tool=EBI

3 August 2024

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A20948793

https://europepmc.org/articles/PMC2950033

3 August 2024

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A20948793

https://europepmc.org/articles/PMC2950033?pdf=render

3 August 2024

file format

Portable Document Format

online access status

open access

content deliverer

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A20948793

3 August 2024

published in

F1000 biology reports

1 reference

31 July 2017

volume

2

1 reference

Comparison of ustekinumab and etanercept for moderate-to-severe psoriasis

31 July 2017

cites work

1 reference

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CCR6 is required for IL-23-induced psoriasis-like inflammation in mice

5 July 2018

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IL-22-producing "T22" T cells account for upregulated IL-22 in atopic dermatitis despite reduced IL-17-producing TH17 T cells

5 July 2018

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The IL-23/Th17 axis in the immunopathogenesis of psoriasis

5 July 2018

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Th17 cytokines stimulate CCL20 expression in keratinocytes in vitro and in vivo: implications for psoriasis pathogenesis

5 July 2018

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The interleukin 23 receptor is essential for the terminal differentiation of interleukin 17-producing effector T helper cells in vivo

5 July 2018

1 reference

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Genome-wide scan reveals association of psoriasis with IL-23 and NF-kappaB pathways

5 July 2018

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Efficacy and safety of ustekinumab, a human interleukin-12/23 monoclonal antibody, in patients with psoriasis: 52-week results from a randomised, double-blind, placebo-controlled trial (PHOENIX 2)

5 July 2018

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Efficacy and safety of ustekinumab, a human interleukin-12/23 monoclonal antibody, in patients with psoriasis: 76-week results from a randomised, double-blind, placebo-controlled trial (PHOENIX 1)

5 July 2018

1 reference

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The differentiation of human T(H)-17 cells requires transforming growth factor-beta and induction of the nuclear receptor RORgammat

5 July 2018

1 reference

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IL-22 is required for Th17 cell-mediated pathology in a mouse model of psoriasis-like skin inflammation

5 July 2018

1 reference

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Development, cytokine profile and function of human interleukin 17-producing helper T cells

5 July 2018

1 reference

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A large-scale genetic association study confirms IL12B and leads to the identification of IL23R as psoriasis-risk genes

5 July 2018

1 reference

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Interleukin-22, a T(H)17 cytokine, mediates IL-23-induced dermal inflammation and acanthosis

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2950033

IL-23 stimulates epidermal hyperplasia via TNF and IL-20R2-dependent mechanisms with implications for psoriasis pathogenesis

5 July 2018

1 reference

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A genome-wide association study identifies IL23R as an inflammatory bowel disease gene

5 July 2018

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Interleukin-23 drives innate and T cell-mediated intestinal inflammation

5 July 2018

1 reference

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IL-23 drives a pathogenic T cell population that induces autoimmune inflammation

5 July 2018

1 reference

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Increased expression of interleukin 23 p19 and p40 in lesional skin of patients with psoriasis vulgaris

5 July 2018

1 reference

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Divergent pro- and antiinflammatory roles for IL-23 and IL-12 in joint autoimmune inflammation

5 July 2018

1 reference

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IL-23 production by cosecretion of endogenous p19 and transgenic p40 in keratin 14/p40 transgenic mice: evidence for enhanced cutaneous immunity

5 July 2018

1 reference

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Interleukin-23 rather than interleukin-12 is the critical cytokine for autoimmune inflammation of the brain

5 July 2018

1 reference

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A receptor for the heterodimeric cytokine IL-23 is composed of IL-12Rbeta1 and a novel cytokine receptor subunit, IL-23R

5 July 2018

1 reference

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Novel p19 protein engages IL-12p40 to form a cytokine, IL-23, with biological activities similar as well as distinct from IL-12

5 July 2018

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5 July 2018

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Sequence variants in the genes for the interleukin-23 receptor (IL23R) and its ligand (IL12B) confer protection against psoriasis.

28 October 2018

1 reference

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Differential activity of IL-12 and IL-23 in mucosal and systemic innate immune pathology.

28 October 2018

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In vitro and in situ expression of IL-23 by keratinocytes in healthy skin and psoriasis lesions: enhanced expression in psoriatic skin.

28 October 2018

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TNF Inhibition Rapidly Down-Regulates Multiple Proinflammatory Pathways in Psoriasis Plaques

28 October 2018

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12 December 2020

Psoriasis Vulgaris Lesions Contain Discrete Populations of Th1 and Th17 T Cells

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12 December 2020

A Phase I Study Evaluating the Safety, Pharmacokinetics, and Clinical Response of a Human IL-12 p40 Antibody in Subjects with Plaque Psoriasis

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12 December 2020

Clinical improvement in chronic plaque-type psoriasis lesions after narrow-band UVB therapy is accompanied by a decrease in the expression of IFN-gamma inducers -- IL-12, IL-18 and IL-23

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12 December 2020

Identifiers

DOI

10.3410/B2-40

1 reference

31 July 2017

1 reference

31 July 2017

1 reference