Regulation of constitutive p50/c-Rel activity via proteasome inhibitor-resistant IkappaBalpha degradation in B cells. (Q34182208)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15143182%20AND%20SRC:MED&resulttype=core&format=json

28 December 2019

title

Regulation of constitutive p50/c-Rel activity via proteasome inhibitor-resistant IkappaBalpha degradation in B cells (English)

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28 December 2019

3

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28 December 2019

author name string

Shelby O'Connor

1

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28 December 2019

Stuart D Shumway

2

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28 December 2019

Colleen E Hayes

4

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28 December 2019

Shigeki Miyamoto

5

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28 December 2019

language of work or name

English

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publication date

1 June 2004

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Molecular and Cellular Biology

28 December 2019

published in

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28 December 2019

volume

24

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28 December 2019

issue

11

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28 December 2019

page(s)

4895-4908

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A mechanistic insight into a proteasome-independent constitutive inhibitor kappaBalpha (IkappaBalpha) degradation and nuclear factor kappaB (NF-kappaB) activation pathway in WEHI-231 B-cells

28 December 2019

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5 July 2018

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Her-2/neu overexpression induces NF-kappaB via a PI3-kinase/Akt pathway involving calpain-mediated degradation of IkappaB-alpha that can be inhibited by the tumor suppressor PTEN.

5 July 2018

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NF-kappaB-inducing kinase regulates the processing of NF-kappaB2 p100

5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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A switch in distinct I kappa B alpha degradation mechanisms mediates constitutive NF-kappa B activation in mature B cells

5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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Signal-dependent degradation of IkappaBalpha is mediated by an inducible destruction box that can be transferred to NF-kappaB, bcl-3 or p53.

5 July 2018

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5 July 2018

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5 July 2018

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Constitutive nuclear factor-kappaB-RelA activation is required for proliferation and survival of Hodgkin's disease tumor cells

5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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Different mechanisms control signal-induced degradation and basal turnover of the NF-kappaB inhibitor IkappaB alpha in vivo

5 July 2018

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5 July 2018

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Constitutive phosphorylation of IkappaBalpha by casein kinase II occurs preferentially at serine 293: requirement for degradation of free IkappaBalpha

5 July 2018

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Casein kinase II phosphorylates I kappa B alpha at S-283, S-289, S-293, and T-291 and is required for its degradation

5 July 2018

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Autoregulation of I kappa B alpha activity

5 July 2018

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5 July 2018

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Enhanced I kappa B alpha degradation is responsible for constitutive NF-kappa B activity in mature murine B-cell lines

5 July 2018

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NF-kappa B controls expression of inhibitor I kappa B alpha: evidence for an inducible autoregulatory pathway

5 July 2018

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The ubiquitin-proteasome pathway is required for processing the NF-kappa B1 precursor protein and the activation of NF-kappa B

5 July 2018

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Sequential induction of NF-kappa B/Rel family proteins during B-cell terminal differentiation

5 July 2018

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A proteasome inhibitor prevents activation of NF-kappa B and stabilizes a newly phosphorylated form of I kappa B-alpha that is still bound to NF-kappa B

5 July 2018

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Human T-cell leukemia virus type I Tax activation of NF-kappa B/Rel involves phosphorylation and degradation of I kappa B alpha and RelA (p65)-mediated induction of the c-rel gene

5 July 2018

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The subunit composition of NF-kappa B complexes changes during B-cell development

5 July 2018

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Signal-induced site-specific phosphorylation targets I kappa B alpha to the ubiquitin-proteasome pathway

5 July 2018

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N- and C-terminal sequences control degradation of MAD3/I kappa B alpha in response to inducers of NF-kappa B activity

5 July 2018

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Multiple nuclear factors interact with the immunoglobulin enhancer sequences

5 July 2018

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c-rel activates but v-rel suppresses transcription from kappa B sites

5 July 2018

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NF-κB and IκBα Are Found in the Mitochondria

5 July 2018

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BAFF-induced NEMO-independent processing of NF-kappa B2 in maturing B cells.

28 October 2018

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Resolution of three nonproliferative immature splenic B cell subsets reveals multiple selection points during peripheral B cell maturation

28 October 2018

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An Essential Role for BAFF in the Normal Development of B Cells Through a BCMA-Independent Pathway

28 October 2018

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Bcmd decreases the life span of B-2 but not B-1 cells in A/WySnJ mice

28 October 2018

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12 December 2020

Constitutive nuclear translocation of NF-kappa B in B cells in the absence of I kappa B degradation

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12 December 2020

Expression of a dominant-negative mutant inhibitor-kappaBalpha of nuclear factor-kappaB in human head and neck squamous cell carcinoma inhibits survival, proinflammatory cytokine expression, and tumor growth in vivo

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12 December 2020

Genetic studies of B-lymphocyte deficiency and mastocytosis in strain A/WySnJ mice

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12 December 2020

Tyrosine phosphorylation of I kappa B-alpha activates NF-kappa B without proteolytic degradation of I kappa B-alpha

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12 December 2020

10.1128/MCB.24.11.4895-4908.2004

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15143182%20AND%20SRC:MED&resulttype=core&format=json

28 December 2019

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15143182%20AND%20SRC:MED&resulttype=core&format=json

28 December 2019

PubMed publication ID

15143182

1 reference