Ubiquitin C-terminal hydrolase L1 is required for pancreatic beta cell survival and function in lipotoxic conditions (Q34228778)

31 July 2017

Ubiquitin C-terminal hydrolase L1 is required for pancreatic beta cell survival and function in lipotoxic conditions (English)

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31 July 2017

K Y Chu

1

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31 July 2017

H Li

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2

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31 July 2017

K Wada

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3

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31 July 2017

J D Johnson

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4

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31 July 2017

25 October 2011

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31 July 2017

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31 July 2017

55

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31 July 2017

1

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31 July 2017

128-140

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https://scigraph.springernature.com/pub.10.1007/s00125-011-2323-1

31 July 2017

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cites work

Beta-cell deficit and increased beta-cell apoptosis in humans with type 2 diabetes

1 reference

https://api.crossref.org/works/10.1007%2FS00125-011-2323-1

Functional pancreatic beta-cell mass: involvement in type 2 diabetes and therapeutic intervention

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00125-011-2323-1

Basic Medical Research Award. The ubiquitin system.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00125-011-2323-1

Ubiquitination and deubiquitination: targeting of proteins for degradation by the proteasome

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00125-011-2323-1

Ubiquitinated-protein aggregates form in pancreatic beta-cells during diabetes-induced oxidative stress and are regulated by autophagy

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00125-011-2323-1

Essential role of ubiquitin-proteasome system in normal regulation of insulin secretion

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00125-011-2323-1

Degradation of cAMP-responsive element-binding protein by the ubiquitin-proteasome pathway contributes to glucotoxicity in beta-cells and human pancreatic islets

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00125-011-2323-1

The neuron-specific protein PGP 9.5 is a ubiquitin carboxyl-terminal hydrolase

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00125-011-2323-1

Substrate specificity of deubiquitinating enzymes: ubiquitin C-terminal hydrolases

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00125-011-2323-1

A genomic and functional inventory of deubiquitinating enzymes

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00125-011-2323-1

Ubiquitin carboxy-terminal hydrolase L1 binds to and stabilizes monoubiquitin in neuron

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00125-011-2323-1

The UCH-L1 gene encodes two opposing enzymatic activities that affect alpha-synuclein degradation and Parkinson's disease susceptibility

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00125-011-2323-1

Oxidative modifications and down-regulation of ubiquitin carboxyl-terminal hydrolase L1 associated with idiopathic Parkinson's and Alzheimer's diseases

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00125-011-2323-1

UCHL1 is a Parkinson's disease susceptibility gene.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00125-011-2323-1

Proteomic and histochemical analysis of proteins involved in the dying-back-type of axonal degeneration in the gracile axonal dystrophy (gad) mouse

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00125-011-2323-1

PGP 9.5--a new marker for vertebrate neurons and neuroendocrine cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00125-011-2323-1

Developmental pathways during in vitro progression of human islet neogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00125-011-2323-1

Expression of PGP9.5 in ductal cells of the rat pancreas during development and regeneration: can it be a marker for pancreatic progenitor cells?

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00125-011-2323-1

Hypertension, hypercholesterolemia, diabetes, and risk of Parkinson disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00125-011-2323-1

Prospective cohort study of type 2 diabetes and the risk of Parkinson's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00125-011-2323-1

Islet amyloid polypeptide and type 2 diabetes

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00125-011-2323-1

Carboxypeptidase E mediates palmitate-induced beta-cell ER stress and apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00125-011-2323-1

Low antioxidant enzyme gene expression in pancreatic islets compared with various other mouse tissues.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00125-011-2323-1

The role for endoplasmic reticulum stress in diabetes mellitus

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00125-011-2323-1

Endoplasmic reticulum dysfunction--a common denominator for cell injury in acute and degenerative diseases of the brain?

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00125-011-2323-1

Metals, oxidative stress and neurodegenerative disorders

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00125-011-2323-1

Endoplasmic reticulum stress links obesity, insulin action, and type 2 diabetes

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00125-011-2323-1

ATP-citrate lyase reduction mediates palmitate-induced apoptosis in pancreatic beta cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00125-011-2323-1

Gracile axonal dystrophy (GAD), a new neurological mutant in the mouse

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00125-011-2323-1

Nicotinic acid-adenine dinucleotide phosphate-sensitive calcium stores initiate insulin signaling in human beta cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00125-011-2323-1

Increased islet apoptosis in Pdx1+/- mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00125-011-2323-1

A multiubiquitin chain is confined to specific lysine in a targeted short-lived protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00125-011-2323-1

Inhibition of proteolysis and cell cycle progression in a multiubiquitination-deficient yeast mutant

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00125-011-2323-1

Interleukin-6 regulates pancreatic alpha-cell mass expansion

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00125-011-2323-1

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00125-011-2323-1

Staring, a novel E3 ubiquitin-protein ligase that targets syntaxin 1 for degradation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00125-011-2323-1

CSPα promotes SNARE-complex assembly by chaperoning SNAP-25 during synaptic activity.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00125-011-2323-1

β-cell dysfunctional ERAD/ubiquitin/proteasome system in type 2 diabetes mediated by islet amyloid polypeptide-induced UCH-L1 deficiency

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00125-011-2323-1

The role of PGP9.5 as a tumor suppressor gene in human cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00125-011-2323-1

Epigenetic identification of ubiquitin carboxyl-terminal hydrolase L1 as a functional tumor suppressor and biomarker for hepatocellular carcinoma and other digestive tumors.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00125-011-2323-1

Interaction and colocalization of PGP9.5 with JAB1 and p27(Kip1)

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00125-011-2323-1

Emerging roles for the ubiquitin-proteasome system and autophagy in pancreatic beta-cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00125-011-2323-1

Alpha-synuclein promotes SNARE-complex assembly in vivo and in vitro

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00125-011-2323-1

Evidence for a Role of the Ubiquitin-Proteasome Pathway in Pancreatic Islets

21 January 2018

1 reference

12 December 2020

Proteomic analysis of brain proteins in the gracile axonal dystrophy (gad) mouse, a syndrome that emanates from dysfunctional ubiquitin carboxyl-terminal hydrolase L-1, reveals oxidation of key proteins.

1 reference

12 December 2020

Tubular complexes as a source for islet neogenesis in the pancreas of diabetes-prone BB rats

1 reference

12 December 2020

A high concentration of fasting plasma non-esterified fatty acids is a risk factor for the development of NIDDM.

1 reference

12 December 2020

Serial analysis of gene expression in non-small cell lung cancer

1 reference

12 December 2020

Intragenic deletion in the gene encoding ubiquitin carboxy-terminal hydrolase in gad mice

1 reference

12 December 2020

Lipotoxicity in the pathogenesis of obesity-dependent NIDDM. Genetic and clinical implications.

1 reference

12 December 2020

PGP9.5 as a prognostic factor in pancreatic cancer

1 reference

12 December 2020

10.1007/S00125-011-2323-1

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Dimensions Publication ID

31 July 2017

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