Signaling through receptors and scaffolds: independent interactions reduce combinatorial complexity (Q34350920)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15923229%20AND%20SRC:MED&resulttype=core&format=json

12 January 2020

title

Signaling through receptors and scaffolds: independent interactions reduce combinatorial complexity (English)

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12 January 2020

4

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12 January 2020

Jan B. Hoek

series ordinal

3

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12 January 2020

author name string

Nikolay M Borisov

series ordinal

1

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12 January 2020

Nick I Markevich

series ordinal

2

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12 January 2020

language of work or name

English

0 references

publication date

27 May 2005

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12 January 2020

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12 January 2020

volume

89

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12 January 2020

issue

2

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12 January 2020

page(s)

951-966

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Signal processing at the Ras circuit: what shapes Ras activation patterns?

12 January 2020

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Signaling switches and bistability arising from multisite phosphorylation in protein kinase cascades

6 July 2018

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The complexity of complexes in signal transduction.

6 July 2018

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6 July 2018

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The role of Gab family scaffolding adapter proteins in the signal transduction of cytokine and growth factor receptors

6 July 2018

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Molecular Mechanism for a Role of SHP2 in Epidermal Growth Factor Receptor Signaling

6 July 2018

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6 July 2018

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Src phosphorylates Grb2-associated binder 1 upon hepatocyte growth factor stimulation

6 July 2018

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Growth factor receptor-binding protein 10 (Grb10) as a partner of phosphatidylinositol 3-kinase in metabolic insulin action

6 July 2018

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A computational model on the modulation of mitogen-activated protein kinase (MAPK) and Akt pathways in heregulin-induced ErbB signalling

6 July 2018

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Control, exploitation and tolerance of intracellular noise

6 July 2018

1 reference

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Structural biology of insulin and IGF1 receptors: implications for drug design

6 July 2018

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IRS proteins and the common path to diabetes

6 July 2018

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Receptor-specific regulation of phosphatidylinositol 3'-kinase activation by the protein tyrosine phosphatase Shp2.

6 July 2018

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Computational modeling of the dynamics of the MAP kinase cascade activated by surface and internalized EGF receptors

6 July 2018

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SHP-2 is involved in heterodimer specific loss of phosphorylation of Tyr771 in the PDGF beta-receptor

6 July 2018

1 reference

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Insulin signaling pathways in time and space.

6 July 2018

1 reference

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SH2 domains, interaction modules and cellular wiring

6 July 2018

1 reference

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STOCHSIM: modelling of stochastic biomolecular processes.

6 July 2018

1 reference

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Activation of the insulin receptor's kinase domain changes the rate-determining step of substrate phosphorylation

6 July 2018

1 reference

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Cell signaling by receptor tyrosine kinases

6 July 2018

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Molecular model of a lattice of signalling proteins involved in bacterial chemotaxis

6 July 2018

1 reference

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Mechanism of transmembrane signaling: insulin binding and the insulin receptor

6 July 2018

1 reference

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Identification of major tyrosine phosphorylation sites in the human insulin receptor substrate Gab-1 by insulin receptor kinase in vitro

6 July 2018

1 reference

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Scaffold proteins may biphasically affect the levels of mitogen-activated protein kinase signaling and reduce its threshold properties

6 July 2018

1 reference

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A novel positive feedback loop mediated by the docking protein Gab1 and phosphatidylinositol 3-kinase in epidermal growth factor receptor signaling

6 July 2018

1 reference

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Signaling--2000 and beyond

6 July 2018

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Internalized epidermal growth factor receptors participate in the activation of p21(ras) in fibroblasts

6 July 2018

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Effect of epidermal growth factor receptor internalization on regulation of the phospholipase C-gamma1 signaling pathway

6 July 2018

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The Gab1 protein is a docking site for multiple proteins involved in signaling by the B cell antigen receptor.

6 July 2018

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The IRS-signalling system: a network of docking proteins that mediate insulin action

6 July 2018

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Control analysis of metabolic systems involving quasi-equilibrium reactions

6 July 2018

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Mechanistic studies of the dual phosphorylation of mitogen-activated protein kinase

6 July 2018

1 reference

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YMXM motifs and signaling by an insulin receptor substrate 1 molecule without tyrosine phosphorylation sites

6 July 2018

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Interaction between the insulin receptor and its downstream effectors. Use of individually expressed receptor domains for structure/function analysis

6 July 2018

1 reference

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Metabolic regulation and mathematical models

6 July 2018

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Investigation of early events in Fc epsilon RI-mediated signaling using a detailed mathematical model

6 July 2018

1 reference

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The structural biology of growth factor receptor activation

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1366644

Temperature dependence of the epidermal growth factor receptor signaling network can be accounted for by a kinetic model

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1366644

The mechanism of dephosphorylation of extracellular signal-regulated kinase 2 by mitogen-activated protein kinase phosphatase 3.

27 October 2018

1 reference

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Phosphoinositide 3-kinase: the key switch mechanism in insulin signalling

27 October 2018

1 reference

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Predicting temporal fluctuations in an intracellular signalling pathway.

27 October 2018

1 reference

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Control theory of metabolic channelling.

27 October 2018

1 reference

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Localization of the insulin receptor binding sites for the SH2 domain proteins p85, Syp, and GAP.

27 October 2018

1 reference

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Gab1 is required for EGF receptor signaling and the transformation by activated ErbB2

27 October 2018

1 reference

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Presence of Oxidized Cholesterol in Caveolae Uncouples Active Platelet-derived Growth Factor Receptors from Tyrosine Kinase Substrates

27 October 2018

1 reference

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The kinetics of bivalent ligand-bivalent receptor aggregation: ring formation and the breakdown of the equivalent site approximation

9 December 2018

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12 December 2020

An evaluation of the cross-linking model for the interaction of insulin with its receptor

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12 December 2020

Quantification of Short Term Signaling by the Epidermal Growth Factor Receptor

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12 December 2020

Epidermal Growth Factor-induced DNA Synthesis

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12 December 2020

10.1529/BIOPHYSJ.105.060533

Identifiers

DOI

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12 January 2020

1 reference

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12 January 2020

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