Virtual optimization of nasal insulin therapy predicts immunization frequency to be crucial for diabetes protection (Q34355286)

1 August 2017

Virtual optimization of nasal insulin therapy predicts immunization frequency to be crucial for diabetes protection (English)

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1 August 2017

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1

Georgia Fousteri

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1 August 2017

8

Matthias von Herrath

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1 August 2017

Jason R Chan

2

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1 August 2017

Yanan Zheng

3

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1 August 2017

Chan Whiting

4

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1 August 2017

Amy Dave

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1 August 2017

Damien Bresson

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1 August 2017

Michael Croft

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1 August 2017

language of work or name

English

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publication date

23 September 2010

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1 August 2017

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1 August 2017

59

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12

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1 August 2017

3148-3158

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Creative Commons Attribution-NonCommercial-NoDerivs 3.0 Unported

1 August 2017

start time

28 August 2021

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April 2022 Public Data File from Crossref

copyright status

copyrighted

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cites work

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Autoantigen-specific regulatory T cells induced in patients with type 1 diabetes mellitus by insulin B-chain immunotherapy

6 July 2018

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Genetic-induced variations in the GAD65 T-cell repertoire governs efficacy of anti-CD3/GAD65 combination therapy in new-onset type 1 diabetes

6 July 2018

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Central role of defective interleukin-2 production in the triggering of islet autoimmune destruction

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Modulating the natural history of type 1 diabetes in children at high genetic risk by mucosal insulin immunization

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Innocuous IFNgamma induced by adjuvant-free antigen restores normoglycemia in NOD mice through inhibition of IL-17 production

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Mucosal exposure to antigen: cause or cure of type 1 diabetes?

6 July 2018

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Translational mini-review series on type 1 diabetes: Immune-based therapeutic approaches for type 1 diabetes

6 July 2018

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Translational mini-review series on type 1 diabetes: Systematic analysis of T cell epitopes in autoimmune diabetes

6 July 2018

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IL-10 is essential for disease protection following intranasal peptide administration in the C57BL/6 model of EAE

6 July 2018

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Prime role for an insulin epitope in the development of type 1 diabetes in NOD mice

6 July 2018

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Mature high-affinity immune responses to (pro)insulin anticipate the autoimmune cascade that leads to type 1 diabetes

6 July 2018

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Intranasal treatment with ovalbumin but not the major T cell epitope ovalbumin 323-339 generates interleukin-10 secreting T cells and results in the induction of allergen systemic tolerance.

6 July 2018

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Autoreactive T cell responses show proinflammatory polarization in diabetes but a regulatory phenotype in health

6 July 2018

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Disabling an integral CTL epitope allows suppression of autoimmune diabetes by intranasal proinsulin peptide

6 July 2018

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A disease-associated cellular immune response in type 1 diabetics to an immunodominant epitope of insulin

6 July 2018

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6 July 2018

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Kinetics of peptide uptake and tissue distribution following a single intranasal dose of peptide

6 July 2018

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Autoreactive CD4+ T cells protect from autoimmune diabetes via bystander suppression using the IL-4/Stat6 pathway.

6 July 2018

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Aerosol insulin induces regulatory CD8 gamma delta T cells that prevent murine insulin-dependent diabetes

6 July 2018

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Protection of nonobese diabetic mice from diabetes by intranasal or subcutaneous administration of insulin peptide B-(9-23)

6 July 2018

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6 July 2018

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Upregulating CD4+CD25+FOXP3+ regulatory T cells in pancreatic lymph nodes in diabetic NOD mice by adjuvant immunotherapy

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The virtual NOD mouse: applying predictive biosimulation to research in type 1 diabetes.

27 October 2018

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Effects of oral insulin in relatives of patients with type 1 diabetes: The Diabetes Prevention Trial--Type 1.

27 October 2018

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Pancreatic beta-cell function and immune responses to insulin after administration of intranasal insulin to humans at risk for type 1 diabetes

27 October 2018

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CD4+CD25+ regulatory T cells generated in response to insulin B:9-23 peptide prevent adoptive transfer of diabetes by diabetogenic T cells.

27 October 2018

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Nondepleting anti-CD4 monoclonal antibody prevents diabetes and blocks induction of insulin autoantibodies following insulin peptide B:9-23 immunization in the NOD mouse

27 October 2018

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Intranasally administered insulin intended for prevention of type 1 diabetes--a safety study in healthy adults

27 October 2018

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Immunological characterization and therapeutic activity of an altered-peptide ligand, NBI-6024, based on the immunodominant type 1 diabetes autoantigen insulin B-chain (9-23) peptide

27 October 2018

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Cutting edge: a critical role for IL-10 in induction of nasal tolerance in experimental autoimmune myocarditis

27 October 2018

1 reference

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Immunization with DNA encoding an immunodominant peptide of insulin prevents diabetes in NOD mice

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2992777

IL-17 Eliminates the Therapeutic Effects of Myelin Basic Protein-Induced Nasal Tolerance in Experimental Autoimmune Encephalomyelitis by Activating IL-6

27 October 2018

1 reference

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Induction of insulin autoantibodies and protection from diabetes with subcutaneous insulin B:9-23 peptide without adjuvant

9 December 2018

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12 December 2020

Nasal administration of CTB-insulin induces active tolerance against autoimmune diabetes in non-obese diabetic (NOD) mice

1 reference

12 December 2020

Induction of Autoimmune Diabetes by Oral Administration of Autoantigen

1 reference

12 December 2020

Intranasal vaccination with proinsulin DNA induces regulatory CD4+ T cells that prevent experimental autoimmune diabetes

1 reference

12 December 2020

Long-term prevention of diabetes and marked suppression of insulin autoantibodies and insulitis in mice lacking native insulin B9-23 sequence

1 reference

12 December 2020

Altered B:9-23 insulin, when administered intranasally with cholera toxin adjuvant, suppresses the expression of insulin autoantibodies and prevents diabetes

1 reference

12 December 2020

Nasal insulin to prevent type 1 diabetes in children with HLA genotypes and autoantibodies conferring increased risk of disease: a double-blind, randomised controlled trial

1 reference

12 December 2020

Identifiers

DOI

10.2337/DB10-0561

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1 August 2017

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1 August 2017

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