Genetic manipulation of AML1-ETO-induced expansion of hematopoietic precursors in a Drosophila model (Q34374087)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20688956%20AND%20SRC:MED&resulttype=core&format=json

9 February 2020

title

Genetic manipulation of AML1-ETO-induced expansion of hematopoietic precursors in a Drosophila model (English)

1 reference

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9 February 2020

0 references

1

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9 February 2020

Matthew D Cheney

6

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9 February 2020

author name string

Tony Hung

2

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9 February 2020

Tatiana Moroz

3

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9 February 2020

Quynh-Minh Tran

4

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9 February 2020

Sohrab Sidhu

5

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9 February 2020

Nancy A Speck

7

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9 February 2020

Utpal Banerjee

8

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9 February 2020

language of work or name

English

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publication date

5 August 2010

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9 February 2020

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9 February 2020

volume

116

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9 February 2020

issue

22

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9 February 2020

page(s)

4612-4620

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Metabolism and the leukemic stem cell.

9 February 2020

cites work

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Targeting iron homeostasis induces cellular differentiation and synergizes with differentiating agents in acute myeloid leukemia

6 July 2018

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Hematopoietic stem cells in Drosophila

6 July 2018

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Reactive oxygen species prime Drosophila haematopoietic progenitors for differentiation

6 July 2018

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A Drosophila model identifies calpains as modulators of the human leukemogenic fusion protein AML1-ETO

6 July 2018

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Repression of Runx2 by androgen receptor (AR) in osteoblasts and prostate cancer cells: AR binds Runx2 and abrogates its recruitment to DNA

6 July 2018

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Identification of AML1-ETO modulators by chemical genomics

6 July 2018

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Sessile hemocytes as a hematopoietic compartment in Drosophila melanogaster

6 July 2018

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CBFbeta is critical for AML1-ETO and TEL-AML1 activity

6 July 2018

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RUNX1/AML1 DNA-binding domain and ETO/MTG8 NHR2-dimerization domain are critical to AML1-ETO9a leukemogenesis

6 July 2018

1 reference

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Disruption of the NHR4 domain structure in AML1-ETO abrogates SON binding and promotes leukemogenesis

6 July 2018

1 reference

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Modulation of Runx2 activity by estrogen receptor-alpha: implications for osteoporosis and breast cancer

6 July 2018

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Integration of metabolism and inflammation by lipid-activated nuclear receptors

6 July 2018

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FOXO animal models reveal a variety of diverse roles for FOXO transcription factors

6 July 2018

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FOXO-binding partners: it takes two to tango

6 July 2018

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FoxO transcription factors and stem cell homeostasis: insights from the hematopoietic system

6 July 2018

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AML1 mutations induced MDS and MDS/AML in a mouse BMT model

6 July 2018

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The hematopoietic stem cell and its niche: a comparative view

6 July 2018

1 reference

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Retinoic acid signaling in myelopoiesis

6 July 2018

1 reference

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Myeloid translocation gene family members associate with T-cell factors (TCFs) and influence TCF-dependent transcription

6 July 2018

1 reference

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RUNX genes in development and cancer: regulation of viral gene expression and the discovery of RUNX family genes

6 July 2018

1 reference

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Structural basis for recognition of SMRT/N-CoR by the MYND domain and its contribution to AML1/ETO's activity

6 July 2018

1 reference

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FoxOs are critical mediators of hematopoietic stem cell resistance to physiologic oxidative stress

6 July 2018

1 reference

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Ecdysone induction of MsrA protects against oxidative stress in Drosophila

6 July 2018

1 reference

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Melanotic mutants in Drosophila: pathways and phenotypes

6 July 2018

1 reference

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G-CSF induced reactive oxygen species involves Lyn-PI3-kinase-Akt and contributes to myeloid cell growth

6 July 2018

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Nuclear receptors--a perspective from Drosophila

6 July 2018

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Live imaging of wound inflammation in Drosophila embryos reveals key roles for small GTPases during in vivo cell migration

6 July 2018

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Deletion of an AML1-ETO C-terminal NcoR/SMRT-interacting region strongly induces leukemia development

6 July 2018

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Yantar, a conserved arginine-rich protein is involved in Drosophila hemocyte development.

6 July 2018

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6 July 2018

ETO interacting proteins

1 reference

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The 8;21 translocation in leukemogenesis

6 July 2018

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Core-binding factors in hematopoiesis and immune function

6 July 2018

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AML-associated translocation products block vitamin D(3)-induced differentiation by sequestering the vitamin D(3) receptor

6 July 2018

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Runx1 is required for zebrafish blood and vessel development and expression of a human RUNX1-CBF2T1 transgene advances a model for studies of leukemogenesis.

6 July 2018

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Differential control of gene activity by isoforms A, B1 and B2 of the Drosophila ecdysone receptor

6 July 2018

1 reference

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Postembryonic hematopoiesis in Drosophila

6 July 2018

1 reference

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Runt and Lozenge function in Drosophila development

6 July 2018

1 reference

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Specification of Drosophila hematopoietic lineage by conserved transcription factors

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2996118

Embryonic lethality and impairment of haematopoiesis in mice heterozygous for an AML1-ETO fusion gene.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2996118

The t(8;21) translocation in acute myeloid leukemia results in production of an AML1-MTG8 fusion transcript

6 July 2018

1 reference

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Targeted gene expression as a means of altering cell fates and generating dominant phenotypes

6 July 2018

1 reference

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Dual role of wingless signaling in stem-like hematopoietic precursor maintenance in Drosophila

6 July 2018

1 reference

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Constitutive activation of Akt by Flt3 internal tandem duplications is necessary for increased survival, proliferation, and myeloid transformation.

27 October 2018

1 reference

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Antagonistic actions of ecdysone and insulins determine final size in Drosophila.

27 October 2018

1 reference

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Evidence that nervy, the Drosophila homolog of ETO/MTG8, promotes mechanosensory organ development by enhancing Notch signaling

27 October 2018

1 reference

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The Drosophila lymph gland as a developmental model of hematopoiesis

27 October 2018

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The t(8;21) translocation converts AML1 into a constitutive transcriptional repressor

27 October 2018

1 reference

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Increased expression of Drosophila tetraspanin, Tsp68C, suppresses the abnormal proliferation of ytr-deficient and Ras/Raf-activated hemocytes

27 October 2018

1 reference

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The two origins of hemocytes in Drosophila.

27 October 2018

1 reference

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Catalase expression in Drosophila melanogaster is responsive to ecdysone and exhibits both transcriptional and post-transcriptional regulation.

27 October 2018

1 reference

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Expression of a knocked-in AML1-ETO leukemia gene inhibits the establishment of normal definitive hematopoiesis and directly generates dysplastic hematopoietic progenitors.

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2996118

Drosophila tissues with different metamorphic responses to ecdysone express different ecdysone receptor isoforms

27 October 2018

1 reference

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Analysis of genes under the downstream control of the t(8;21) fusion protein AML1-MTG8: overexpression of the TIS11b (ERF-1, cMG1) gene induces myeloid cell proliferation in response to G-CSF

27 October 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/20688956

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1182/BLOOD-2010-03-276998

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20688956%20AND%20SRC:MED&resulttype=core&format=json

9 February 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20688956%20AND%20SRC:MED&resulttype=core&format=json

9 February 2020

1 reference