Nuclear PRAS40 couples the Akt/mTORC1 signaling axis to the RPL11-HDM2-p53 nucleolar stress response pathway. (Q34437857)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24704832%20AND%20SRC:MED&resulttype=core&format=json

13 March 2020

title

Nuclear PRAS40 couples the Akt/mTORC1 signaling axis to the RPL11-HDM2-p53 nucleolar stress response pathway (English)

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13 March 2020

1

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13 March 2020

author name string

Z Li

2

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13 March 2020

D Cheng

3

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13 March 2020

J Peng

4

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13 March 2020

H Fu

5

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13 March 2020

language of work or name

English

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publication date

7 April 2014

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13 March 2020

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13 March 2020

volume

34

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issue

12

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13 March 2020

page(s)

1487-1498

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https://scigraph.springernature.com/pub.10.1038/onc.2014.91

13 March 2020

exact match

0 references

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6 July 2018

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6 July 2018

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6 July 2018

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6 July 2018

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6 July 2018

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6 July 2018

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6 July 2018

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6 July 2018

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6 July 2018

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6 July 2018

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PRAS40 is an insulin-regulated inhibitor of the mTORC1 protein kinase

6 July 2018

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6 July 2018

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6 July 2018

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Insulin-mediated phosphorylation of the proline-rich Akt substrate PRAS40 is impaired in insulin target tissues of high-fat diet-fed rats

6 July 2018

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6 July 2018

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6 July 2018

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Nutrient regulates Tor1 nuclear localization and association with rDNA promoter.

6 July 2018

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Modulation of proline-rich akt substrate survival signaling pathways by oxidative stress in mouse brains after transient focal cerebral ischemia

6 July 2018

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Redox regulation of the nutrient-sensitive raptor-mTOR pathway and complex

6 July 2018

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BRAFE600-associated senescence-like cell cycle arrest of human naevi

6 July 2018

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6 July 2018

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Essential role of ribosomal protein L11 in mediating growth inhibition-induced p53 activation

6 July 2018

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Neuroprotective role of a proline-rich Akt substrate in apoptotic neuronal cell death after stroke: relationships with nerve growth factor

6 July 2018

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Ribosomal Protein L11 Negatively Regulates Oncoprotein MDM2 and Mediates a p53-Dependent Ribosomal-Stress Checkpoint Pathway

6 July 2018

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6 July 2018

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6 July 2018

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Identification of a proline-rich Akt substrate as a 14-3-3 binding partner

6 July 2018

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6 July 2018

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Predominant nuclear localization of mammalian target of rapamycin in normal and malignant cells in culture

6 July 2018

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Evidence of p53-dependent cross-talk between ribosome biogenesis and the cell cycle: effects of nucleolar protein Bop1 on G(1)/S transition

6 July 2018

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14-3-3 proteins: structure, function, and regulation

6 July 2018

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A serine/threonine kinase gene defective in Peutz-Jeghers syndrome

6 July 2018

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Peutz-Jeghers syndrome is caused by mutations in a novel serine threonine kinase

6 July 2018

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Identification of the tuberous sclerosis gene TSC1 on chromosome 9q34

6 July 2018

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p53, the cellular gatekeeper for growth and division

6 July 2018

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6 July 2018

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PIM1-activated PRAS40 regulates radioresistance in non-small cell lung cancer cells through interplay with FOXO3a, 14-3-3 and protein phosphatases.

6 July 2018

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Cytoplasmic and nuclear distribution of the protein complexes mTORC1 and mTORC2: rapamycin triggers dephosphorylation and delocalization of the mTORC2 components rictor and sin1.

21 January 2018

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BRAF mutations are sufficient to promote nevi formation and cooperate with p53 in the genesis of melanoma.

21 January 2018

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Akt phosphorylation of BAD couples survival signals to the cell-intrinsic death machinery

21 January 2018

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Telomerase maintains telomere structure in normal human cells.

21 January 2018

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21 January 2018

Identifiers

DOI

10.1038/ONC.2014.91

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24704832%20AND%20SRC:MED&resulttype=core&format=json

Dimensions Publication ID

13 March 2020

0 references

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24704832%20AND%20SRC:MED&resulttype=core&format=json

13 March 2020

PubMed publication ID

24704832

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24704832%20AND%20SRC:MED&resulttype=core&format=json