DNA-damage-induced type I interferon promotes senescence and inhibits stem cell function (Q34474083)

2 August 2017

title

DNA-damage-induced type I interferon promotes senescence and inhibits stem cell function (English)

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2 August 2017

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Christopher J. Lengner

11

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2 August 2017

Qiujing Yu

1

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2 August 2017

Yuliya V Katlinskaya

2

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2 August 2017

Christopher J Carbone

3

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2 August 2017

Bin Zhao

4

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2 August 2017

Kanstantsin V Katlinski

5

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2 August 2017

Hui Zheng

6

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2 August 2017

Manti Guha

7

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2 August 2017

Ning Li

8

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2 August 2017

Qijun Chen

9

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2 August 2017

Ting Yang

10

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2 August 2017

Roger A Greenberg

12

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2 August 2017

F Brad Johnson

13

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2 August 2017

Serge Y Fuchs

14

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2 August 2017

publication date

23 April 2015

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2 August 2017

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2 August 2017

volume

11

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2 August 2017

issue

5

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2 August 2017

page(s)

785-797

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STING-Dependent Cytosolic DNA Sensing Promotes Radiation-Induced Type I Interferon-Dependent Antitumor Immunity in Immunogenic Tumors.

2 August 2017

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6 July 2018

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6 July 2018

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6 July 2018

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6 July 2018

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6 July 2018

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6 July 2018

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6 July 2018

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6 July 2018

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6 July 2018

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6 July 2018

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An interferon-related gene signature for DNA damage resistance is a predictive marker for chemotherapy and radiation for breast cancer

6 July 2018

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6 July 2018

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6 July 2018

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6 July 2018

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6 July 2018

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6 July 2018

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6 July 2018

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Senescence and tumour clearance is triggered by p53 restoration in murine liver carcinomas

6 July 2018

1 reference

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6 July 2018

1 reference

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6 July 2018

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Antiviral innate immunity pathways.

6 July 2018

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DNA damage signaling and p53-dependent senescence after prolonged beta-interferon stimulation

6 July 2018

1 reference

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ATM-dependent phosphorylation of ATF2 is required for the DNA damage response

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4426031

Induction of IFN-regulated factors and antitumoral surveillance by transfected placebo plasmid DNA.

6 July 2018

1 reference

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Telomere shortening exposes functions for the mouse Werner and Bloom syndrome genes

6 July 2018

1 reference

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Ageing, repetitive genomes and DNA damage

6 July 2018

1 reference

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Stability of homologue of Slimb F-box protein is regulated by availability of its substrate

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4426031

DNA damage foci at dysfunctional telomeres

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4426031

Integration of interferon-alpha/beta signalling to p53 responses in tumour suppression and antiviral defence.

6 July 2018

1 reference

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Viruses and interferon: a fight for supremacy

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4426031

Interferon regulatory factor-3 is an in vivo target of DNA-PK.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4426031

Activation of interferon regulatory factor 3 in response to DNA-damaging agents

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4426031

p53 deficiency rescues the adverse effects of telomere loss and cooperates with telomere dysfunction to accelerate carcinogenesis

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4426031

Virus-dependent phosphorylation of the IRF-3 transcription factor regulates nuclear translocation, transactivation potential, and proteasome-mediated degradation

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4426031

Essential role of mouse telomerase in highly proliferative organs

6 July 2018

1 reference

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Telomere shortening and tumor formation by mouse cells lacking telomerase RNA

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4426031

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4426031

Telomere reduction in human colorectal carcinoma and with ageing

6 July 2018

1 reference

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Cyclophosphamide induces a type I interferon-associated sterile inflammatory response signature in cancer patients' blood cells: implications for cancer chemoimmunotherapy.

6 July 2018

1 reference

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Quantitative assessment of markers for cell senescence.

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4426031

Interferon regulatory factor-2 protects quiescent hematopoietic stem cells from type I interferon-dependent exhaustion.

27 October 2018

1 reference

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IFNalpha activates dormant haematopoietic stem cells in vivo.

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4426031

Contribution of interferon-beta to the immune activation induced by double-stranded DNA.

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4426031

Telomere dysfunction induces environmental alterations limiting hematopoietic stem cell function and engraftment

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4426031

The mammalian UV response: mechanism of DNA damage induced gene expression

9 December 2018

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12 December 2020

Longevity, Stress Response, and Cancer in Aging Telomerase-Deficient Mice

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12 December 2020

Cdkn1a deletion improves stem cell function and lifespan of mice with dysfunctional telomeres without accelerating cancer formation

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12 December 2020

Alterations of the systemic environment are the primary cause of impaired B and T lymphopoiesis in telomere-dysfunctional mice

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12 December 2020

10.1016/J.CELREP.2015.03.069

Identifiers

DOI

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2 August 2017

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2 August 2017

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