A genetic screen identifies Tor as an interactor of VAPB in a Drosophila model of amyotrophic lateral sclerosis. (Q34515862)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25361581%20AND%20SRC:MED&resulttype=core&format=json

22 February 2020

title

A genetic screen identifies Tor as an interactor of VAPB in a Drosophila model of amyotrophic lateral sclerosis (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25361581%20AND%20SRC:MED&resulttype=core&format=json

amyotrophic lateral sclerosis

22 February 2020

main subject

Drosophila

0 references

0 references

Tsc1 Dmel_CG6147

1 reference

Transcriptional Adaptor 2b Dmel_CG9638

1 reference

Pickpocket 30 Dmel_CG18110

1 reference

Target of rapamycin Dmel_CG5092

1 reference

Nucleoporin 75kD Dmel_CG5733

1 reference

Uncharacterized protein Dmel_CG6048

1 reference

Thor Dmel_CG8846

1 reference

Ribosomal protein S6 kinase Dmel_CG10539

1 reference

Superoxide dismutase 1 Dmel_CG11793

1 reference

NADH dehydrogenase (ubiquinone) 20 kDa subunit Dmel_CG9172

1 reference

Senthilkumar Deivasigamani

author

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25361581%20AND%20SRC:MED&resulttype=core&format=json

22 February 2020

author name string

Hemant Kumar Verma

2

1 reference

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22 February 2020

Ryu Ueda

3

1 reference

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22 February 2020

Anuradha Ratnaparkhi

4

1 reference

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22 February 2020

Girish S Ratnaparkhi

5

1 reference

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22 February 2020

publication date

31 October 2014

1 reference

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22 February 2020

1 reference

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22 February 2020

volume

3

1 reference

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22 February 2020

issue

11

1 reference

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22 February 2020

page(s)

1127-1138

1 reference

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Creative Commons Attribution 3.0 Unported

22 February 2020

copyright license

start time

3 September 2020

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

0 references

cites work

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7 July 2018

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7 July 2018

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7 July 2018

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7 July 2018

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7 July 2018

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7 July 2018

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7 July 2018

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7 July 2018

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7 July 2018

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7 July 2018

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7 July 2018

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7 July 2018

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7 July 2018

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7 July 2018

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7 July 2018

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7 July 2018

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7 July 2018

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The amyotrophic lateral sclerosis 8 protein VAPB is cleaved, secreted, and acts as a ligand for Eph receptors

7 July 2018

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7 July 2018

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7 July 2018

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C. elegans model identifies genetic modifiers of alpha-synuclein inclusion formation during aging

7 July 2018

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7 July 2018

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7 July 2018

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A mutation in human VAP-B--MSP domain, present in ALS patients, affects the interaction with other cellular proteins

7 July 2018

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Huntingtin interacting proteins are genetic modifiers of neurodegeneration

7 July 2018

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7 July 2018

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Oxysterol-binding protein and vesicle-associated membrane protein-associated protein are required for sterol-dependent activation of the ceramide transport protein

7 July 2018

1 reference

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Differential regulation of endoplasmic reticulum structure through VAP-Nir protein interaction

7 July 2018

1 reference

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A mutation in the vesicle-trafficking protein VAPB causes late-onset spinal muscular atrophy and amyotrophic lateral sclerosis

7 July 2018

1 reference

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Inhibition of mTOR induces autophagy and reduces toxicity of polyglutamine expansions in fly and mouse models of Huntington disease

7 July 2018

1 reference

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7 July 2018

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Drosophila VAP-33A directs bouton formation at neuromuscular junctions in a dosage-dependent manner

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4232771

Mouse VAP33 is associated with the endoplasmic reticulum and microtubules

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4232771

Molecular cloning and characterization of mammalian homologues of vesicle-associated membrane protein-associated (VAMP-associated) proteins

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4232771

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7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4232771

A VAMP-binding protein from Aplysia required for neurotransmitter release

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4232771

Targets for Cell Cycle Arrest by the Immunosuppressant Rapamycin in Yeast

7 July 2018

1 reference

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ALS/FTLD-linked TDP-43 regulates neurite morphology and cell survival in differentiated neurons.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4232771

Investigating the contribution of VAPB/ALS8 loss of function in amyotrophic lateral sclerosis

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4232771

Tuberous sclerosis complex regulates Drosophila neuromuscular junction growth via the TORC2/Akt pathway

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4232771

Drosophila Vap-33 is required for axonal localization of Dscam isoforms.

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4232771

TOR is required for the retrograde regulation of synaptic homeostasis at the Drosophila neuromuscular junction.

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4232771

Rapamycin treatment augments motor neuron degeneration in SOD1(G93A) mouse model of amyotrophic lateral sclerosis.

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4232771

Amyotrophic lateral sclerosis mutant vesicle-associated membrane protein-associated protein-B transgenic mice develop TAR-DNA-binding protein-43 pathology.

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4232771

Evidence for a common pathway linking neurodegenerative diseases.

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4232771

Ablation of the UPR-mediator CHOP restores motor function and reduces demyelination in Charcot-Marie-Tooth 1B mice

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4232771

Small molecule enhancers of rapamycin-induced TOR inhibition promote autophagy, reduce toxicity in Huntington's disease models and enhance killing of mycobacteria by macrophages

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4232771

Drosophila immunity: a large-scale in vivo RNAi screen identifies five serine proteases required for Toll activation

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4232771

Kynurenine metabolism in plasma and in red blood cells in Parkinson's disease

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4232771

Amyotrophic lateral sclerosis

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4232771

A common founder for amyotrophic lateral sclerosis type 8 (ALS8) in the Brazilian population

9 December 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/25361581

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

A mutation in VAPB that causes amyotrophic lateral sclerosis also causes a nuclear envelope defect

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/25361581

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1242/BIO.201410066

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25361581%20AND%20SRC:MED&resulttype=core&format=json

22 February 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25361581%20AND%20SRC:MED&resulttype=core&format=json

22 February 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25361581%20AND%20SRC:MED&resulttype=core&format=json