Malaria Parasite Liver Infection and Exoerythrocytic Biology (Q34552223)

3 August 2017

title

Malaria Parasite Liver Infection and Exoerythrocytic Biology (English)

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3 August 2017

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2

Stefan H I Kappe

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3 August 2017

1

Ashley M Vaughan

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3 August 2017

publication date

27 February 2017

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Cold Spring Harbor Perspectives in Medicine

3 August 2017

published in

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3 August 2017

volume

7

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3 August 2017

issue

6

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Host cell transcriptional profiling during malaria liver stage infection reveals a coordinated and sequential set of biological events

3 August 2017

cites work

1 reference

https://api.crossref.org/works/10.1101%2FCSHPERSPECT.A025486

Targeted deletion of SAP1 abolishes the expression of infectivity factors necessary for successful malaria parasite liver infection

21 January 2018

1 reference

https://api.crossref.org/works/10.1101%2FCSHPERSPECT.A025486

Two Plasmodium 6-Cys family-related proteins have distinct and critical roles in liver-stage development

21 January 2018

1 reference

https://api.crossref.org/works/10.1101%2FCSHPERSPECT.A025486

Robust expansion of human hepatocytes in Fah-/-/Rag2-/-/Il2rg-/- mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1101%2FCSHPERSPECT.A025486

Release of hepatic Plasmodium yoelii merozoites into the pulmonary microvasculature

21 January 2018

1 reference

https://api.crossref.org/works/10.1101%2FCSHPERSPECT.A025486

Two Plasmodium rhomboid proteases preferentially cleave different adhesins implicated in all invasive stages of malaria

21 January 2018

1 reference

https://api.crossref.org/works/10.1101%2FCSHPERSPECT.A025486

Cellular interactions of Plasmodium liver stage with its host mammalian cell.

21 January 2018

1 reference

https://api.crossref.org/works/10.1101%2FCSHPERSPECT.A025486

Sporozoite immunization of human volunteers under chemoprophylaxis induces functional antibodies against pre-erythrocytic stages of Plasmodium falciparum

21 January 2018

1 reference

https://api.crossref.org/works/10.1101%2FCSHPERSPECT.A025486

LAP-like process as an immune mechanism downstream of IFN-γ in control of the human malaria Plasmodium vivax liver stage

21 January 2018

1 reference

https://api.crossref.org/works/10.1101%2FCSHPERSPECT.A025486

A Plasmodium phospholipase is involved in disruption of the liver stage parasitophorous vacuole membrane

21 January 2018

1 reference

https://api.crossref.org/works/10.1101%2FCSHPERSPECT.A025486

Superior antimalarial immunity after vaccination with late liver stage-arresting genetically attenuated parasites

21 January 2018

1 reference

https://api.crossref.org/works/10.1101%2FCSHPERSPECT.A025486

Kinetic flux profiling elucidates two independent acetyl-CoA biosynthetic pathways in Plasmodium falciparum

21 January 2018

1 reference

https://api.crossref.org/works/10.1101%2FCSHPERSPECT.A025486

Clonal conditional mutagenesis in malaria parasites

21 January 2018

1 reference

https://api.crossref.org/works/10.1101%2FCSHPERSPECT.A025486

The malaria circumsporozoite protein has two functional domains, each with distinct roles as sporozoites journey from mosquito to mammalian host

21 January 2018

1 reference

https://api.crossref.org/works/10.1101%2FCSHPERSPECT.A025486

The Plasmodium circumsporozoite protein is proteolytically processed during cell invasion

21 January 2018

1 reference

https://api.crossref.org/works/10.1101%2FCSHPERSPECT.A025486

Heparan sulfate proteoglycans provide a signal to Plasmodium sporozoites to stop migrating and productively invade host cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1101%2FCSHPERSPECT.A025486

The cellular and molecular basis for malaria parasite invasion of the human red blood cell

21 January 2018

1 reference

https://api.crossref.org/works/10.1101%2FCSHPERSPECT.A025486

A Plasmodium yoelii Mei2-Like RNA Binding Protein Is Essential for Completion of Liver Stage Schizogony

21 January 2018

1 reference

https://api.crossref.org/works/10.1101%2FCSHPERSPECT.A025486

Autophagy in infection, inflammation, and immunity

21 January 2018

1 reference

https://api.crossref.org/works/10.1101%2FCSHPERSPECT.A025486

Correlates of protective immunity following whole sporozoite vaccination against malaria

21 January 2018

1 reference

https://api.crossref.org/works/10.1101%2FCSHPERSPECT.A025486

Genetically attenuated P36p-deficient Plasmodium berghei sporozoites confer long-lasting and partial cross-species protection.

21 January 2018

1 reference

https://api.crossref.org/works/10.1101%2FCSHPERSPECT.A025486

Features of autophagic cell death in Plasmodium liver-stage parasites

21 January 2018

1 reference

https://api.crossref.org/works/10.1101%2FCSHPERSPECT.A025486

Plasmodium sporozoite-host interactions from the dermis to the hepatocyte

21 January 2018

1 reference

https://api.crossref.org/works/10.1101%2FCSHPERSPECT.A025486

Shedding of TRAP by a rhomboid protease from the malaria sporozoite surface is essential for gliding motility and sporozoite infectivity

21 January 2018

1 reference

https://api.crossref.org/works/10.1101%2FCSHPERSPECT.A025486

Role of Plasmodium berghei cGMP-dependent protein kinase in late liver stage development

21 January 2018

1 reference

https://api.crossref.org/works/10.1101%2FCSHPERSPECT.A025486

A key role for lipoic acid synthesis during Plasmodium liver stage development

21 January 2018

1 reference

https://api.crossref.org/works/10.1101%2FCSHPERSPECT.A025486

Inhibition of development of exoerythrocytic forms of malaria parasites by gamma-interferon

21 January 2018

1 reference

https://api.crossref.org/works/10.1101%2FCSHPERSPECT.A025486

Vaccine-induced monoclonal antibodies targeting circumsporozoite protein prevent Plasmodium falciparum infection

21 January 2018

1 reference

https://api.crossref.org/works/10.1101%2FCSHPERSPECT.A025486

Anti-CD81 but not anti-SR-BI blocks Plasmodium falciparum liver infection in a humanized mouse model

21 January 2018

1 reference

https://api.crossref.org/works/10.1101%2FCSHPERSPECT.A025486

Malaria circumsporozoite protein binds to heparan sulfate proteoglycans associated with the surface membrane of hepatocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1101%2FCSHPERSPECT.A025486

Host cell entry by apicomplexa parasites requires actin polymerization in the host cell

21 January 2018

1 reference

https://api.crossref.org/works/10.1101%2FCSHPERSPECT.A025486

Hostile takeover by Plasmodium: reorganization of parasite and host cell membranes during liver stage egress

21 January 2018

1 reference

https://api.crossref.org/works/10.1101%2FCSHPERSPECT.A025486

The spatiotemporal dynamics and membranous features of the Plasmodium liver stage tubovesicular network

21 January 2018

1 reference

https://api.crossref.org/works/10.1101%2FCSHPERSPECT.A025486

Stress granules and Plasmodium liver stage infection

21 January 2018

1 reference

https://api.crossref.org/works/10.1101%2FCSHPERSPECT.A025486

Inactivation of a Plasmodium apicoplast protein attenuates formation of liver merozoites

21 January 2018

1 reference

https://api.crossref.org/works/10.1101%2FCSHPERSPECT.A025486

Parasite-induced ER stress response in hepatocytes facilitates Plasmodium liver stage infection

21 January 2018

1 reference

https://api.crossref.org/works/10.1101%2FCSHPERSPECT.A025486

Two proteins with 6-cys motifs are required for malarial parasites to commit to infection of the hepatocyte

21 January 2018

1 reference

https://api.crossref.org/works/10.1101%2FCSHPERSPECT.A025486

LISP1 is important for the egress of Plasmodium berghei parasites from liver cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1101%2FCSHPERSPECT.A025486

Host cell phosphatidylcholine is a key mediator of malaria parasite survival during liver stage infection.

21 January 2018

1 reference

https://api.crossref.org/works/10.1101%2FCSHPERSPECT.A025486

Metamorphosis of the malaria parasite in the liver is associated with organelle clearance

21 January 2018

1 reference

https://api.crossref.org/works/10.1101%2FCSHPERSPECT.A025486

Characterization of the ATG8-conjugation system in 2 Plasmodium species with special focus on the liver stage: possible linkage between the apicoplastic and autophagic systems?

21 January 2018

1 reference

https://api.crossref.org/works/10.1101%2FCSHPERSPECT.A025486

Genetically attenuated Plasmodium berghei liver stages induce sterile protracted protection that is mediated by major histocompatibility complex Class I-dependent interferon-gamma-producing CD8+ T cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1101%2FCSHPERSPECT.A025486

Transformation of Sporozoites into Early Exoerythrocytic Malaria Parasites Does Not Require Host Cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1101%2FCSHPERSPECT.A025486

Conservation of a gliding motility and cell invasion machinery in Apicomplexan parasites

21 January 2018

1 reference

https://api.crossref.org/works/10.1101%2FCSHPERSPECT.A025486

Malaria parasite liver stages render host hepatocytes susceptible to mitochondria-initiated apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1101%2FCSHPERSPECT.A025486

Suppression of host p53 is critical for Plasmodium liver-stage infection

21 January 2018

1 reference

https://api.crossref.org/works/10.1101%2FCSHPERSPECT.A025486

Malaria parasites target the hepatocyte receptor EphA2 for successful host infection

21 January 2018

1 reference

https://api.crossref.org/works/10.1101%2FCSHPERSPECT.A025486

Plasmodium yoelii sporozoites with simultaneous deletion of P52 and P36 are completely attenuated and confer sterile immunity against infection

21 January 2018

1 reference

https://api.crossref.org/works/10.1101%2FCSHPERSPECT.A025486

Plasmodium salvages cholesterol internalized by LDL and synthesized de novo in the liver

21 January 2018

1 reference

https://api.crossref.org/works/10.1101%2FCSHPERSPECT.A025486

Innate recognition of malarial parasites by mammalian hosts

21 January 2018

1 reference

https://api.crossref.org/works/10.1101%2FCSHPERSPECT.A025486

Host-cell sensors for Plasmodium activate innate immunity against liver-stage infection

21 January 2018

1 reference

https://api.crossref.org/works/10.1101%2FCSHPERSPECT.A025486

Enzymes involved in plastid-targeted phosphatidic acid synthesis are essential for Plasmodium yoelii liver-stage development

21 January 2018

1 reference

https://api.crossref.org/works/10.1101%2FCSHPERSPECT.A025486

The host endocytic pathway is essential for Plasmodium berghei late liver stage development.

21 January 2018

1 reference

https://api.crossref.org/works/10.1101%2FCSHPERSPECT.A025486

A microscale human liver platform that supports the hepatic stages of Plasmodium falciparum and vivax

21 January 2018

1 reference

https://api.crossref.org/works/10.1101%2FCSHPERSPECT.A025486

Cultivation of the liver forms of Plasmodium vivax in human hepatocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1101%2FCSHPERSPECT.A025486

Complete development of hepatic stages of Plasmodium falciparum in vitro

21 January 2018

1 reference

https://api.crossref.org/works/10.1101%2FCSHPERSPECT.A025486

Malaria parasites—discovery of the early liver form

21 January 2018

1 reference

https://api.crossref.org/works/10.1101%2FCSHPERSPECT.A025486

L-FABP is a critical host factor for successful malaria liver stage development.

21 January 2018

1 reference

https://api.crossref.org/works/10.1101%2FCSHPERSPECT.A025486

Disruption of the Plasmodium falciparum liver-stage antigen-1 locus causes a differentiation defect in late liver-stage parasites

21 January 2018

1 reference

https://api.crossref.org/works/10.1101%2FCSHPERSPECT.A025486

A next-generation genetically attenuated Plasmodium falciparum parasite created by triple gene deletion

21 January 2018

1 reference

https://api.crossref.org/works/10.1101%2FCSHPERSPECT.A025486

Plasmodium vivax liver stage development and hypnozoite persistence in human liver-chimeric mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1101%2FCSHPERSPECT.A025486

Plasmodium yoelii macrophage migration inhibitory factor is necessary for efficient liver-stage development

21 January 2018

1 reference

https://api.crossref.org/works/10.1101%2FCSHPERSPECT.A025486

Interferon-mediated innate immune responses against malaria parasite liver stages

21 January 2018

1 reference

https://api.crossref.org/works/10.1101%2FCSHPERSPECT.A025486

The human malaria parasite Pfs47 gene mediates evasion of the mosquito immune system

21 January 2018

1 reference

https://api.crossref.org/works/10.1101%2FCSHPERSPECT.A025486

Plasmodium liver stage developmental arrest by depletion of a protein at the parasite-host interface

21 January 2018

1 reference

https://api.crossref.org/works/10.1101%2FCSHPERSPECT.A025486

Genetically modified Plasmodium parasites as a protective experimental malaria vaccine

21 January 2018

1 reference

https://api.crossref.org/works/10.1101%2FCSHPERSPECT.A025486

A new approach to generate a safe double-attenuated Plasmodium liver stage vaccine

21 January 2018

1 reference

https://api.crossref.org/works/10.1101%2FCSHPERSPECT.A025486

Human iPSC-derived hepatocyte-like cells support Plasmodium liver-stage infection in vitro

21 January 2018

1 reference

https://api.crossref.org/works/10.1101%2FCSHPERSPECT.A025486

Protective Immunity produced by the Injection of X-irradiated Sporozoites of Plasmodium berghei

21 January 2018

1 reference

https://api.crossref.org/works/10.1101%2FCSHPERSPECT.A025486

Liver-specific protein 2: a Plasmodium protein exported to the hepatocyte cytoplasm and required for merozoite formation

21 January 2018

1 reference

https://api.crossref.org/works/10.1101%2FCSHPERSPECT.A025486

Plasmodium pyruvate dehydrogenase activity is only essential for the parasite's progression from liver infection to blood infection.

21 January 2018

1 reference

https://api.crossref.org/works/10.1101%2FCSHPERSPECT.A025486

Plasmodium berghei Δp52&p36 parasites develop independent of a parasitophorous vacuole membrane in Huh-7 liver cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1101%2FCSHPERSPECT.A025486

Proteins of the malaria parasite sexual stages: expression, function and potential for transmission blocking strategies

21 January 2018

1 reference

https://api.crossref.org/works/10.1101%2FCSHPERSPECT.A025486

Long-term live imaging reveals cytosolic immune responses of host hepatocytes against Plasmodium infection and parasite escape mechanisms

21 January 2018

1 reference

https://api.crossref.org/works/10.1101%2FCSHPERSPECT.A025486

Letter: Sporozoite induced immunity in man against an Ethiopian strain of Plasmodium falciparum

21 January 2018

1 reference

https://api.crossref.org/works/10.1101%2FCSHPERSPECT.A025486

Multidrug ATP-binding cassette transporters are essential for hepatic development of Plasmodium sporozoites

21 January 2018

1 reference

https://api.crossref.org/works/10.1101%2FCSHPERSPECT.A025486

CD81 is required for rhoptry discharge during host cell invasion by Plasmodium yoelii sporozoites

21 January 2018

1 reference

https://api.crossref.org/works/10.1101%2FCSHPERSPECT.A025486

Plasmodium falciparum infection and exoerythrocytic development in mice with chimeric human livers

21 January 2018

1 reference

https://api.crossref.org/works/10.1101%2FCSHPERSPECT.A025486

Model for in vivo assessment of humoral protection against malaria sporozoite challenge by passive transfer of monoclonal antibodies and immune serum

21 January 2018

1 reference

https://api.crossref.org/works/10.1101%2FCSHPERSPECT.A025486

Mechanisms of stage-transcending protection following immunization of mice with late liver stage-arresting genetically attenuated malaria parasites

21 January 2018

1 reference

https://api.crossref.org/works/10.1101%2FCSHPERSPECT.A025486

ZIPCO, a putative metal ion transporter, is crucial for Plasmodium liver-stage development

21 January 2018

1 reference

https://api.crossref.org/works/10.1101%2FCSHPERSPECT.A025486

The Plasmodium berghei sexual stage antigen PSOP12 induces anti-malarial transmission blocking immunity both in vivo and in vitro

21 January 2018

1 reference

https://api.crossref.org/works/10.1101%2FCSHPERSPECT.A025486

Protection against malaria by intravenous immunization with a nonreplicating sporozoite vaccine

21 January 2018

1 reference

https://api.crossref.org/works/10.1101%2FCSHPERSPECT.A025486

A sporozoite asparagine-rich protein controls initiation of Plasmodium liver stage development

21 January 2018

1 reference

https://api.crossref.org/works/10.1101%2FCSHPERSPECT.A025486

Hepatocyte CD81 is required for Plasmodium falciparum and Plasmodium yoelii sporozoite infectivity

21 January 2018

1 reference

https://api.crossref.org/works/10.1101%2FCSHPERSPECT.A025486

Cholesterol contributes to the organization of tetraspanin-enriched microdomains and to CD81-dependent infection by malaria sporozoites

21 January 2018

1 reference

https://api.crossref.org/works/10.1101%2FCSHPERSPECT.A025486

First-in-human evaluation of genetically attenuated Plasmodium falciparum sporozoites administered by bite of Anopheles mosquitoes to adult volunteers

21 January 2018

1 reference

https://api.crossref.org/works/10.1101%2FCSHPERSPECT.A025486

GFP-targeting allows visualization of the apicoplast throughout the life cycle of live malaria parasites

21 January 2018

1 reference

https://api.crossref.org/works/10.1101%2FCSHPERSPECT.A025486

Organelle segregation into Plasmodium liver stage merozoites

21 January 2018

1 reference

https://api.crossref.org/works/10.1101%2FCSHPERSPECT.A025486

Manipulation of host hepatocytes by the malaria parasite for delivery into liver sinusoids

21 January 2018

1 reference

https://api.crossref.org/works/10.1101%2FCSHPERSPECT.A025486

Alteration of the parasite plasma membrane and the parasitophorous vacuole membrane during exo-erythrocytic development of malaria parasites

21 January 2018

1 reference

https://api.crossref.org/works/10.1101%2FCSHPERSPECT.A025486

Cell Surface Expression of Major Histocompatibility Complex Class I Molecules Is Reduced in Hepatitis C Virus Subgenomic Replicon-Expressing Cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1101%2FCSHPERSPECT.A025486

Quantitative isolation and in vivo imaging of malaria parasite liver stages

21 January 2018

1 reference

https://api.crossref.org/works/10.1101%2FCSHPERSPECT.A025486

Protracted sterile protection with Plasmodium yoelii pre-erythrocytic genetically attenuated parasite malaria vaccines is independent of significant liver-stage persistence and is mediated by CD8+ T cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1101%2FCSHPERSPECT.A025486

A combined transcriptome and proteome survey of malaria parasite liver stages

21 January 2018

1 reference

https://api.crossref.org/works/10.1101%2FCSHPERSPECT.A025486

Identification of additional members define a Plasmodium falciparum gene superfamily which includes Pfs48/45 and Pfs230.

21 January 2018

1 reference

https://api.crossref.org/works/10.1101%2FCSHPERSPECT.A025486

Host PI(3,5)P2 activity is required for Plasmodium berghei growth during liver stage infection

21 January 2018

1 reference

https://api.crossref.org/works/10.1101%2FCSHPERSPECT.A025486

Preerythrocytic, live-attenuated Plasmodium falciparum vaccine candidates by design

21 January 2018

1 reference

https://api.crossref.org/works/10.1101%2FCSHPERSPECT.A025486

The liver stage of Plasmodium berghei inhibits host cell apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1101%2FCSHPERSPECT.A025486

Genetically attenuated, P36p-deficient malarial sporozoites induce protective immunity and apoptosis of infected liver cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1101%2FCSHPERSPECT.A025486

Three members of the 6-cys protein family of Plasmodium play a role in gamete fertility

21 January 2018

1 reference

https://api.crossref.org/works/10.1101%2FCSHPERSPECT.A025486

Gene disruption of Plasmodium falciparum p52 results in attenuation of malaria liver stage development in cultured primary human hepatocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1101%2FCSHPERSPECT.A025486

Type II fatty acid biosynthesis is essential for Plasmodium falciparum sporozoite development in the midgut of Anopheles mosquitoes

21 January 2018

1 reference

https://api.crossref.org/works/10.1101%2FCSHPERSPECT.A025486

A genetically attenuated malaria vaccine candidate based on P. falciparum b9/slarp gene-deficient sporozoites

21 January 2018

1 reference

https://api.crossref.org/works/10.1101%2FCSHPERSPECT.A025486

Type II fatty acid synthesis is essential only for malaria parasite late liver stage development

21 January 2018

1 reference

https://api.crossref.org/works/10.1101%2FCSHPERSPECT.A025486

Complete Plasmodium falciparum liver-stage development in liver-chimeric mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1101%2FCSHPERSPECT.A025486

Plasmodium falciparum genetic crosses in a humanized mouse model

21 January 2018

1 reference

https://api.crossref.org/works/10.1101%2FCSHPERSPECT.A025486

Scavenger receptor BI boosts hepatocyte permissiveness to Plasmodium infection

21 January 2018

1 reference

https://api.crossref.org/works/10.1101%2FCSHPERSPECT.A025486

The Fatty Acid Biosynthesis Enzyme FabI Plays a Key Role in the Development of Liver-Stage Malarial Parasites

21 January 2018

1 reference

https://api.crossref.org/works/10.1101%2FCSHPERSPECT.A025486

The cytoskeleton and motility in apicomplexan invasion

21 January 2018

1 reference

12 December 2020

Plasmodium ookinete invasion of the mosquito midgut

1 reference

12 December 2020

Establishment of a human hepatocyte line that supports in vitro development of the exo-erythrocytic stages of the malaria parasites Plasmodium falciparum and P. vivax.

1 reference

12 December 2020

Immunization of man against sporozite-induced falciparum malaria

1 reference

12 December 2020

Demonstration of hypnozoites in sporozoite-transmitted Plasmodium vivax infection.

1 reference

12 December 2020

10.1101/CSHPERSPECT.A025486

Identifiers

DOI

1 reference

3 August 2017

0 references

1 reference