Resveratrol potentiates glucose-stimulated insulin secretion in INS-1E beta-cells and human islets through a SIRT1-dependent mechanism. (Q34675695)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21163946%20AND%20SRC:MED&resulttype=core&format=json

18 January 2020

title

Resveratrol potentiates glucose-stimulated insulin secretion in INS-1E beta-cells and human islets through a SIRT1-dependent mechanism (English)

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18 January 2020

1 reference

5

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18 January 2020

author name string

Laurène Vetterli

1

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18 January 2020

Thierry Brun

2

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18 January 2020

Laurianne Giovannoni

3

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18 January 2020

Domenico Bosco

4

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18 January 2020

language of work or name

English

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publication date

16 December 2010

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Journal of Biological Chemistry

18 January 2020

published in

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18 January 2020

volume

286

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18 January 2020

issue

8

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18 January 2020

page(s)

6049-6060

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Silencing of the mitochondrial NADH shuttle component aspartate-glutamate carrier AGC1/Aralar1 in INS-1E cells and rat islets.

18 January 2020

cites work

1 reference

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7 July 2018

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Resveratrol enhances insulin secretion by blocking K(ATP) and K(V) channels of beta cells.

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7 July 2018

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Increasing uncoupling protein-2 in pancreatic beta cells does not alter glucose-induced insulin secretion but decreases production of reactive oxygen species.

7 July 2018

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Resveratrol improves mitochondrial function and protects against metabolic disease by activating SIRT1 and PGC-1alpha

7 July 2018

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Resveratrol improves health and survival of mice on a high-calorie diet

7 July 2018

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SIRT4 inhibits glutamate dehydrogenase and opposes the effects of calorie restriction in pancreatic beta cells

7 July 2018

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7 July 2018

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7 July 2018

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Sirt1 regulates insulin secretion by repressing UCP2 in pancreatic beta cells

7 July 2018

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Inhibition of SIRT1 catalytic activity increases p53 acetylation but does not alter cell survival following DNA damage

7 July 2018

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7 July 2018

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7 July 2018

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7 July 2018

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7 July 2018

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7 July 2018

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7 July 2018

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7 July 2018

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7 July 2018

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7 July 2018

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Glucose Sensitivity and Metabolism-Secretion Coupling Studied during Two-Year Continuous Culture in INS-1E Insulinoma Cells

7 July 2018

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7 July 2018

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Sir2 regulates skeletal muscle differentiation as a potential sensor of the redox state

7 July 2018

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The key role of anaplerosis and cataplerosis for citric acid cycle function.

7 July 2018

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Identification of a small molecule inhibitor of Sir2p

7 July 2018

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A transcription factor regulatory circuit in differentiated pancreatic cells

7 July 2018

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Loss of HNF-1alpha function in mice leads to abnormal expression of genes involved in pancreatic islet development and metabolism

7 July 2018

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Increased uncoupling protein-2 levels in beta-cells are associated with impaired glucose-stimulated insulin secretion: mechanism of action

7 July 2018

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Pdx1 level defines pancreatic gene expression pattern and cell lineage differentiation

7 July 2018

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7 July 2018

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7 July 2018

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7 July 2018

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7 July 2018

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7 July 2018

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7 July 2018

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7 July 2018

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7 July 2018

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7 July 2018

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7 July 2018

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Transcriptional activation of the GLUT2 gene by the IPF-1/STF-1/IDX-1 homeobox factor

7 July 2018

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Resveratrol inhibits electrical activity and insulin release from insulinoma cells by block of voltage-gated Ca+ channels and swelling-dependent Cl- currents.

7 July 2018

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Resveratrol, a red wine antioxidant, possesses an insulin-like effect in streptozotocin-induced diabetic rats

26 October 2018

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Increased dosage of mammalian Sir2 in pancreatic beta cells enhances glucose-stimulated insulin secretion in mice

26 October 2018

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Mitochondria-derived glutamate at the interplay between branched-chain amino acid and glucose-induced insulin secretion

26 October 2018

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Reduction in pancreatic transcription factor PDX-1 impairs glucose-stimulated insulin secretion

26 October 2018

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Mitochondrial glutamate acts as a messenger in glucose-induced insulin exocytosis.

26 October 2018

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Resveratrol inhibits insulin secretion from rat pancreatic islets

26 October 2018

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12 December 2020

Effects of adenoviral overexpression of uncoupling protein-2 and -3 on mitochondrial respiration in insulinoma cells

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12 December 2020

Uncoupling protein 2, in vivo distribution, induction upon oxidative stress, and evidence for translational regulation

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PDX-1 induces insulin and glucokinase gene expressions in alphaTC1 clone 6 cells in the presence of betacellulin

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12 December 2020

Identifiers

DOI

10.1074/JBC.M110.176842

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21163946%20AND%20SRC:MED&resulttype=core&format=json

18 January 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21163946%20AND%20SRC:MED&resulttype=core&format=json

18 January 2020

1 reference